|
US6777217B1
(en)
|
1996-03-26 |
2004-08-17 |
President And Fellows Of Harvard College |
Histone deacetylases, and uses related thereto
|
|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
WO2001070675A2
(en)
|
2000-03-24 |
2001-09-27 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
JPWO2002074298A1
(ja)
|
2001-03-21 |
2004-07-08 |
小野薬品工業株式会社 |
Ｉｌ−６産生阻害剤
|
|
US7244853B2
(en)
|
2001-05-09 |
2007-07-17 |
President And Fellows Of Harvard College |
Dioxanes and uses thereof
|
|
ES2294190T3
(es)
|
2001-11-01 |
2008-04-01 |
Janssen Pharmaceutica N.V. |
Derivados de amida como inhibidores de la glucogeno sintasa quinasa 3-beta.
|
|
US7154002B1
(en)
|
2002-10-08 |
2006-12-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US7381825B2
(en)
|
2003-03-17 |
2008-06-03 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
WO2005007091A2
(en)
|
2003-07-07 |
2005-01-27 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
|
CN101010298A
(zh)
|
2004-04-05 |
2007-08-01 |
默克Hdac研究有限责任公司 |
组蛋白脱乙酰酶抑制剂前药
|
|
US8999289B2
(en)
|
2005-03-22 |
2015-04-07 |
President And Fellows Of Harvard College |
Treatment of protein degradation disorders
|
|
JP2009509923A
(ja)
|
2005-08-26 |
2009-03-12 |
メシルジーン、インコーポレイテッド |
ヒストンデアセチラーゼのベンゾジアゼピン及びベンゾピペラジン類似体阻害薬
|
|
US8222423B2
(en)
|
2006-02-14 |
2012-07-17 |
Dana-Farber Cancer Institute, Inc. |
Bifunctional histone deacetylase inhibitors
|
|
US8304451B2
(en)
|
2006-05-03 |
2012-11-06 |
President And Fellows Of Harvard College |
Histone deacetylase and tubulin deacetylase inhibitors
|
|
US20100278782A1
(en)
|
2006-06-12 |
2010-11-04 |
Vrije Universiteit Brussel |
Differentiation of rat liver epithelial cells into hepatocyte-like cells
|
|
ES2288802B1
(es)
|
2006-07-07 |
2008-12-16 |
Universidad De Granada |
Nuevos derivados de ftalimida como inhibidores de las histonas desacetilasas.
|
|
AU2007296743B2
(en)
|
2006-09-11 |
2012-02-16 |
Curis, Inc. |
Tyrosine kinase inhibitors containing a zinc binding moiety
|
|
KR101325374B1
(ko)
|
2008-02-19 |
2013-11-08 |
가부시키가이샤 오츠까 세이야꾸 고죠 |
신체 기능의 회복에 유용한 경구 또는 경장 조성물
|
|
AU2009274549B2
(en)
|
2008-07-23 |
2014-05-01 |
Dana-Farber Cancer Institute, Inc. |
Deacetylase inhibitors and uses thereof
|
|
EP2429987A4
(en)
|
2009-05-15 |
2012-10-03 |
Korea Res Inst Chem Tech |
AMIDE COMPOUND, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
|
|
WO2011019393A2
(en)
|
2009-08-11 |
2011-02-17 |
President And Fellows Of Harvard College |
Class- and isoform-specific hdac inhibitors and uses thereof
|
|
KR101445012B1
(ko)
*
|
2009-12-17 |
2014-09-26 |
머크 샤프 앤드 돔 코포레이션 |
Ｓｙｋ 억제제로서의 아미노피리미딘
|
|
US20130040998A1
(en)
|
2010-01-08 |
2013-02-14 |
Dana-Farber Cancer Institute, Inc. |
Fluorinated hdac inhibitors and uses thereof
|
|
PH12012501492B1
(en)
|
2010-01-22 |
2020-01-24 |
Acetylon Pharmaceuticals Inc |
Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
EP2571352A4
(en)
|
2010-05-21 |
2014-09-17 |
Sloan Kettering Inst Cancer |
SELECTIVE HDAC HEMMER
|
|
WO2012018499A2
(en)
|
2010-08-05 |
2012-02-09 |
Acetylon Pharmaceuticals |
Specific regulation of cytokine levels by hdac6 inhibitors
|
|
NZ610225A
(en)
|
2010-11-16 |
2015-08-28 |
Acetylon Pharmaceuticals Inc |
Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
EP2734500A4
(en)
|
2011-07-20 |
2015-04-08 |
Gen Hospital Corp |
SELECTIVE HISTONDEACETYLASE-6 INHIBITORS FOR THE TREATMENT OF BONE DISORDERS
|
|
EP2760843B1
(en)
*
|
2011-09-26 |
2016-03-02 |
Bristol-Myers Squibb Company |
Selective nr2b antagonists
|
|
JP5724851B2
(ja)
*
|
2011-11-30 |
2015-05-27 |
東レ株式会社 |
Ｎ−（ヨードフェニル）ピリミジニルアミン誘導体の製造方法
|
|
WO2013158984A1
(en)
|
2012-04-19 |
2013-10-24 |
Acetylon Pharmaceuticals, Inc. |
Biomarkers to identify patients that will respond to treatment and treating such patients
|
|
EP2906211A4
(en)
|
2012-10-12 |
2016-04-20 |
Univ Pennsylvania |
PYRIMIDINHYDROXY AMID COMPOUNDS AS A PROTEIN DEACETYLASE INHIBITOR AND METHOD OF USE THEREOF
|
|
US9145412B2
(en)
|
2012-11-02 |
2015-09-29 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC1 and HDAC2 inhibitors
|
|
US9139583B2
(en)
|
2013-02-01 |
2015-09-22 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC3 inhibitors
|
|
US9096549B2
(en)
|
2013-02-01 |
2015-08-04 |
Acetylon Pharmaceuticals, Inc. |
Selective HDAC3 inhibitors
|
|
US20140357512A1
(en)
|
2013-06-03 |
2014-12-04 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase (hdac) biomarkers in multiple myeloma
|
|
WO2015042418A1
(en)
|
2013-09-20 |
2015-03-26 |
Acetylon Pharmaceuticals, Inc. |
Treatment of diseases caused by abnormal lymphocyte function with an hdac6 inhibitor
|
|
WO2015054099A1
(en)
*
|
2013-10-08 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and either her2 inhibitors or pi3k inhibitors
|
|
US9278963B2
(en)
|
2013-10-10 |
2016-03-08 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
|
|
WO2015054197A1
(en)
|
2013-10-10 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Hdac inhibitors, alone or in combination with btk inhibitors, for treating non-hodgkin's lymphoma
|
|
ES2818933T3
(es)
|
2013-10-10 |
2021-04-14 |
Acetylon Pharmaceuticals Inc |
Inhibidores de la HDAC en combinación con los inhibidores de la pi3k, para el tratamiento del linfoma no Hodgkin
|
|
CA2926808A1
(en)
|
2013-10-11 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and immunomodulatory drugs
|
|
US10660890B2
(en)
|
2013-10-24 |
2020-05-26 |
National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs), U.S. Government Nih Division Of Extramural Inventions And Technology Resources (Deitr) |
Treatment of polycystic diseases with an HDAC6 inhibitor
|
|
WO2015084905A1
(en)
|
2013-12-03 |
2015-06-11 |
Acetylon Pharmaceuticals, Inc. |
Combinations of histone deacetylase inhibitors and immunomodulatory drugs
|
|
EP3084446B1
(en)
|
2013-12-20 |
2022-12-14 |
Acetylon Pharmaceuticals, Inc. |
Histone deacetylase 6 (hdac6) biomarkers in multiple myeloma
|
|
US9464073B2
(en)
|
2014-02-26 |
2016-10-11 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
|
|
US20150359794A1
(en)
|
2014-06-13 |
2015-12-17 |
Buck Institute For Research On Aging |
Impairment of the large ribosomal subunit protein rpl24 by depletion or acetylation
|
|
JP6952602B2
(ja)
|
2014-07-07 |
2021-10-20 |
アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
ヒストンデアセチラーゼ阻害剤による白血病の治療
|
|
US20160137630A1
(en)
|
2014-10-08 |
2016-05-19 |
Acetylon Pharmaceuticals, Inc. |
Induction of gata2 by hdac1 and hdac2 inhibitors
|
|
US20160158231A1
(en)
|
2014-12-05 |
2016-06-09 |
Vib Vzw |
Pyrimidine hydroxy amide compounds for treating peripheral neuropathy
|
|
US9937174B2
(en)
|
2014-12-05 |
2018-04-10 |
University of Modena and Reggio Emilia |
Combinations of histone deacetylase inhibitors and bendamustine
|
|
AU2015360270B9
(en)
|
2014-12-12 |
2019-12-05 |
Regenacy Pharmaceuticals, Llc |
Piperidine derivatives as HDAC1/2 inhibitors
|
|
US20160339022A1
(en)
|
2015-04-17 |
2016-11-24 |
Acetylon Pharmaceuticals Inc. |
Treatment of neuroblastoma with histone deacetylase inhibitors
|
|
US10272084B2
(en)
|
2015-06-01 |
2019-04-30 |
Regenacy Pharmaceuticals, Llc |
Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
|
|
EP3303306B1
(en)
|
2015-06-08 |
2020-02-12 |
Acetylon Pharmaceuticals, Inc. |
Crystalline forms of a histone deacetylase inhibitor
|
|
JP6873053B2
(ja)
|
2015-06-08 |
2021-05-19 |
アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
タンパク質脱アセチル化阻害剤の製造方法
|
|
ES2929032T3
(es)
|
2016-08-08 |
2022-11-24 |
Acetylon Pharmaceuticals Inc |
Combinaciones farmacéuticas de inhibidores de histona desacetilasa 6 y anticuerpos inhibidores de CD20 y usos de los mismos
|