JP2019508387A5 - - Google Patents
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- Publication number
- JP2019508387A5 JP2019508387A5 JP2018538156A JP2018538156A JP2019508387A5 JP 2019508387 A5 JP2019508387 A5 JP 2019508387A5 JP 2018538156 A JP2018538156 A JP 2018538156A JP 2018538156 A JP2018538156 A JP 2018538156A JP 2019508387 A5 JP2019508387 A5 JP 2019508387A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- process according
- palladium
- platinum
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662289390P | 2016-02-01 | 2016-02-01 | |
| US62/289,390 | 2016-02-01 | ||
| PCT/EP2017/052050 WO2017134051A1 (en) | 2016-02-01 | 2017-01-31 | Improved process for the preparation of osimertinib (azd9291) or a salt thereof, and "azd9291 aniline" or a salt thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019508387A JP2019508387A (ja) | 2019-03-28 |
| JP2019508387A5 true JP2019508387A5 (enExample) | 2020-01-30 |
| JP6812449B2 JP6812449B2 (ja) | 2021-01-13 |
Family
ID=57984913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018538156A Active JP6812449B2 (ja) | 2016-02-01 | 2017-01-31 | オシメルチニブ（ａｚｄ９２９１）またはその塩、および「ａｚｄ９２９１アニリン」またはその塩を製造するための向上したプロセス |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11180477B2 (enExample) |
| EP (1) | EP3411038B1 (enExample) |
| JP (1) | JP6812449B2 (enExample) |
| KR (1) | KR102749892B1 (enExample) |
| CN (1) | CN108495632B (enExample) |
| AR (1) | AR107494A1 (enExample) |
| AU (1) | AU2017214243B2 (enExample) |
| BR (1) | BR112018014712B1 (enExample) |
| CA (1) | CA3011809C (enExample) |
| CO (1) | CO2018007008A2 (enExample) |
| ES (1) | ES2834608T3 (enExample) |
| IL (1) | IL260665B (enExample) |
| MX (1) | MX378363B (enExample) |
| MY (1) | MY185367A (enExample) |
| RU (1) | RU2733376C2 (enExample) |
| TW (1) | TWI745345B (enExample) |
| WO (1) | WO2017134051A1 (enExample) |
| ZA (1) | ZA201805790B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109311858B (zh) | 2016-05-26 | 2021-12-03 | 里科瑞尔姆Ip控股有限责任公司 | Egfr抑制剂化合物 |
| CN107556293B (zh) * | 2017-09-19 | 2019-12-03 | 福建省微生物研究所 | 一种奥西替尼的合成工艺 |
| WO2021111462A1 (en) * | 2019-12-02 | 2021-06-10 | Natco Pharma Limited | An improved process for the preparation of osimertinib mesylate |
| US11780824B2 (en) * | 2020-12-16 | 2023-10-10 | Scinopharm Taiwan, Ltd. | Process for preparing osimertinib or a salt thereof |
| AU2022340897A1 (en) | 2021-09-02 | 2024-03-14 | Synthon B.V. | A process for making osimertinib |
| WO2025124936A1 (en) | 2023-12-15 | 2025-06-19 | Synthon B.V. | A process for making osimertinib |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070401A (en) * | 1972-02-19 | 1978-01-24 | Mitsui Toatsu Chemicals Inc. | Method for the preparation of a halogenated aromatic amine |
| EP2736895B1 (en) * | 2011-07-27 | 2016-01-06 | Astrazeneca AB | 2-(2,4,5-substituted-anilino) pyrimidine derivatives as egfr modulators useful for treating cancer |
| PE20170268A1 (es) * | 2014-06-19 | 2017-04-21 | Ariad Pharma Inc | Compuestos de heteroarilo para la inhibicion de cinasa |
| CN104817541B (zh) * | 2015-05-11 | 2017-06-16 | 苏州东南药业股份有限公司 | 一种抗肿瘤药物的合成方法 |
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2017
- 2017-01-26 TW TW106103351A patent/TWI745345B/zh active
- 2017-01-31 RU RU2018130327A patent/RU2733376C2/ru active
- 2017-01-31 AR ARP170100246A patent/AR107494A1/es unknown
- 2017-01-31 US US16/074,119 patent/US11180477B2/en active Active
- 2017-01-31 BR BR112018014712-5A patent/BR112018014712B1/pt active IP Right Grant
- 2017-01-31 CN CN201780007929.9A patent/CN108495632B/zh active Active
- 2017-01-31 WO PCT/EP2017/052050 patent/WO2017134051A1/en not_active Ceased
- 2017-01-31 MY MYPI2018702645A patent/MY185367A/en unknown
- 2017-01-31 MX MX2018008966A patent/MX378363B/es unknown
- 2017-01-31 CA CA3011809A patent/CA3011809C/en active Active
- 2017-01-31 KR KR1020187025038A patent/KR102749892B1/ko active Active
- 2017-01-31 AU AU2017214243A patent/AU2017214243B2/en active Active
- 2017-01-31 EP EP17703696.9A patent/EP3411038B1/en active Active
- 2017-01-31 JP JP2018538156A patent/JP6812449B2/ja active Active
- 2017-01-31 ES ES17703696T patent/ES2834608T3/es active Active
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2018
- 2018-07-04 CO CONC2018/0007008A patent/CO2018007008A2/es unknown
- 2018-07-19 IL IL260665A patent/IL260665B/en unknown
- 2018-08-29 ZA ZA2018/05790A patent/ZA201805790B/en unknown