AR107494A1 - Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y “azd9291 anilina” o una sal de la misma - Google Patents

Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y “azd9291 anilina” o una sal de la misma

Info

Publication number
AR107494A1
AR107494A1 ARP170100246A ARP170100246A AR107494A1 AR 107494 A1 AR107494 A1 AR 107494A1 AR P170100246 A ARP170100246 A AR P170100246A AR P170100246 A ARP170100246 A AR P170100246A AR 107494 A1 AR107494 A1 AR 107494A1
Authority
AR
Argentina
Prior art keywords
azd9291
salt
aniline
preparation
formula
Prior art date
Application number
ARP170100246A
Other languages
English (en)
Spanish (es)
Inventor
Alexander Telford
Alistair John Boyd
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57984913&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR107494(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR107494A1 publication Critical patent/AR107494A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP170100246A 2016-02-01 2017-01-31 Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y “azd9291 anilina” o una sal de la misma AR107494A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662289390P 2016-02-01 2016-02-01

Publications (1)

Publication Number Publication Date
AR107494A1 true AR107494A1 (es) 2018-05-02

Family

ID=57984913

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170100246A AR107494A1 (es) 2016-02-01 2017-01-31 Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y “azd9291 anilina” o una sal de la misma

Country Status (18)

Country Link
US (1) US11180477B2 (enExample)
EP (1) EP3411038B1 (enExample)
JP (1) JP6812449B2 (enExample)
KR (1) KR102749892B1 (enExample)
CN (1) CN108495632B (enExample)
AR (1) AR107494A1 (enExample)
AU (1) AU2017214243B2 (enExample)
BR (1) BR112018014712B1 (enExample)
CA (1) CA3011809C (enExample)
CO (1) CO2018007008A2 (enExample)
ES (1) ES2834608T3 (enExample)
IL (1) IL260665B (enExample)
MX (1) MX378363B (enExample)
MY (1) MY185367A (enExample)
RU (1) RU2733376C2 (enExample)
TW (1) TWI745345B (enExample)
WO (1) WO2017134051A1 (enExample)
ZA (1) ZA201805790B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX383920B (es) 2016-05-26 2025-03-14 Recurium Ip Holdings Llc Compuestos inhibidores de egfr.
CN107556293B (zh) * 2017-09-19 2019-12-03 福建省微生物研究所 一种奥西替尼的合成工艺
WO2021111462A1 (en) * 2019-12-02 2021-06-10 Natco Pharma Limited An improved process for the preparation of osimertinib mesylate
US11780824B2 (en) * 2020-12-16 2023-10-10 Scinopharm Taiwan, Ltd. Process for preparing osimertinib or a salt thereof
JP2024530782A (ja) 2021-09-02 2024-08-23 シントン・ビー．ブイ． オシメルチニブの製造方法
WO2025124936A1 (en) 2023-12-15 2025-06-19 Synthon B.V. A process for making osimertinib

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070401A (en) * 1972-02-19 1978-01-24 Mitsui Toatsu Chemicals Inc. Method for the preparation of a halogenated aromatic amine
EP4119551A1 (en) * 2011-07-27 2023-01-18 Astrazeneca AB 2-(2,4,5-substituted-anilino)pyrimidine compounds
EP3778584A1 (en) * 2014-06-19 2021-02-17 ARIAD Pharmaceuticals, Inc. Production process of 2-chloro-4-heteroaryl-pyrimidine derivatives
CN104817541B (zh) * 2015-05-11 2017-06-16 苏州东南药业股份有限公司 一种抗肿瘤药物的合成方法

Also Published As

Publication number Publication date
JP6812449B2 (ja) 2021-01-13
RU2018130327A3 (enExample) 2020-03-26
MY185367A (en) 2021-05-11
CA3011809C (en) 2024-02-27
RU2733376C2 (ru) 2020-10-01
ZA201805790B (en) 2024-10-30
AU2017214243B2 (en) 2019-07-18
AU2017214243A1 (en) 2018-09-06
CA3011809A1 (en) 2017-08-10
CN108495632B (zh) 2021-12-31
EP3411038A1 (en) 2018-12-12
ES2834608T3 (es) 2021-06-18
TWI745345B (zh) 2021-11-11
WO2017134051A1 (en) 2017-08-10
MX378363B (es) 2025-03-10
KR102749892B1 (ko) 2025-01-07
CN108495632A (zh) 2018-09-04
TW201736364A (zh) 2017-10-16
EP3411038B1 (en) 2020-09-09
BR112018014712A2 (pt) 2018-12-11
US11180477B2 (en) 2021-11-23
CO2018007008A2 (es) 2018-07-19
IL260665B (en) 2021-08-31
JP2019508387A (ja) 2019-03-28
BR112018014712B1 (pt) 2023-10-31
KR20180101610A (ko) 2018-09-12
RU2018130327A (ru) 2020-03-04
MX2018008966A (es) 2018-09-03
US20210122734A1 (en) 2021-04-29

Similar Documents

Publication Publication Date Title
AR107494A1 (es) Proceso para la preparación de osimertinib (azd9291) o una sal del mismo, y “azd9291 anilina” o una sal de la misma
AR076027A1 (es) Metodos e intermediarios para la preparacion de agentes farmaceuticos
AR126445A2 (es) Metodo para preparar inhibidores de btk
AR093244A1 (es) Compuestos de benceno sustituidos utilizables en el tratamiento de trastornos mediados por ezh2
MX375970B (es) Compuestos de triazolopirimidina y usos de los mismos.
CO6630136A2 (es) Procedimiento para la preparación de 4-{4[({4-cloro-3-(trifluorometil) fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridina-2-carbocamida, sus sales y su monohidrato
AR074845A1 (es) Procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable
PE20180327A1 (es) Proceso para preparar 4-amino-piridazinas
MX381408B (es) Mejoras en o con relación a compuestos orgánicos.
BR112015029714A2 (pt) processo para preparar derivados de 4,6-bis(ariloxi)pirimidina
BR112012017994B8 (pt) composição líquida, uso de uma composição líquida, e, métodos para preparar uma composição líquida e para tratamento de um distúrbio
AR080921A1 (es) Proceso para la preparacion de amidas de acido pirazolcarboxilico
MX394430B (es) Proceso para la preparación de 5-fluoro-1h-pirazoles.
AR109248A1 (es) Procedimiento para la preparación de 4-fenilbutirato y sus usos
AR093787A1 (es) Derivados de aminociclobutano, su metodo de preparacion y su uso como medicamentos
AR101136A1 (es) Proceso para la preparación de ácidos 3-hidroxipicolínicos
MX2017006298A (es) Proceso para producir acido acetico introduciendo un compuesto de litio.
AR087345A1 (es) Metodos para la preparacion de compuestos de tiofeno
AR066054A1 (es) Proceso para preparar galantamina
MX2018004338A (es) Proceso para sintesis de pirfenidona.
MX383794B (es) Procedimiento para la preparacion de un derivado de furfural.
ES2531069T3 (es) Proceso para la producción de tartrato de L-carnitina
AR102980A1 (es) Un proceso para la fabricación de idalopirdina
AR106195A1 (es) Proceso para la preparación de ácido 1-(4-metanosulfonil-2-trifluorometil-bencil)-2-metil-1h-pirrolo[2,3-b]piridin-3-il-acético e intermediarios de dicha síntesis
AR093373A1 (es) Procedimiento de sintesis del (2e)-3-(3,4-dimetoxifenil)prop-2-enonitrilo y aplicacion a la sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable

Legal Events

Date Code Title Description
FG Grant, registration