|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
SG48759A1
(en)
|
1990-01-12 |
2002-07-23 |
Abgenix Inc |
Generation of xenogenic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5562909A
(en)
|
1993-07-12 |
1996-10-08 |
Massachusetts Institute Of Technology |
Phosphazene polyelectrolytes as immunoadjuvants
|
|
AU7642494A
(en)
|
1993-08-31 |
1995-03-22 |
Gliatech Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
JPH11514333A
(ja)
|
1995-03-14 |
1999-12-07 |
プレーシス ファーマスーティカルズ インコーポレイテッド |
アミロイドの凝集の調節剤
|
|
WO1997021728A1
(en)
*
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6043283A
(en)
*
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
US6071493A
(en)
*
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US7179892B2
(en)
*
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20080050367A1
(en)
*
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
TWI239847B
(en)
*
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US6923964B1
(en)
*
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
US6761888B1
(en)
*
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7964192B1
(en)
*
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US7790856B2
(en)
*
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6913745B1
(en)
*
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7588766B1
(en)
*
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US6936252B2
(en)
*
|
1998-07-27 |
2005-08-30 |
Microbial Technics Limited |
Streptococcus pneumoniae proteins and nucleic acid molecules
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
WO2000068263A2
(en)
*
|
1999-05-05 |
2000-11-16 |
Neurochem, Inc. |
Stereoselective antifibrillogenic peptides and peptidomimetics thereof
|
|
UA81216C2
(en)
*
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
IL149924A0
(en)
|
1999-11-29 |
2002-11-10 |
Neurochem Inc |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
EP3150633A1
(en)
|
2000-02-24 |
2017-04-05 |
Washington University St. Louis |
Humanized antibodies that sequester amyloid beta peptide
|
|
US7700751B2
(en)
*
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
TWI255272B
(en)
*
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
ATE385811T1
(de)
|
2000-12-19 |
2008-03-15 |
Palatin Technologies Inc |
Identifizierung zielgerichteter faltungsstellen in peptiden und proteinen
|
|
DE10101430B4
(de)
*
|
2001-01-13 |
2008-10-02 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Lösliche cyclische Analoga zur Modulation der Amyloidogenese
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
US7314974B2
(en)
*
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
MY139983A
(en)
*
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2487528A1
(en)
*
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation
|
|
WO2010011999A2
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
CA2511606A1
(en)
|
2002-12-24 |
2004-07-15 |
Neurochem (International) Limited |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
ES2344645T3
(es)
|
2003-02-10 |
2010-09-02 |
Applied Molecular Evolution, Inc. |
Moleculas de union al abeta.
|
|
TWI306458B
(en)
*
|
2003-05-30 |
2009-02-21 |
Elan Pharma Int Ltd |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20070110750A1
(en)
|
2003-09-12 |
2007-05-17 |
The Regents Of The University Of California |
Monoclonal antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
CA2560618A1
(en)
*
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
PE20061329A1
(es)
*
|
2004-12-15 |
2006-12-08 |
Neuralab Ltd |
Anticuerpos ab humanizados para mejorar la cognicion
|
|
US7625560B2
(en)
*
|
2004-12-15 |
2009-12-01 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
EP1676859A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
CA2609980C
(en)
|
2005-05-27 |
2015-10-13 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
JP2009516654A
(ja)
|
2005-11-10 |
2009-04-23 |
ロスキャンプ リサーチ, エルエルシー |
A−ベータペプチドによる血管新生の調節
|
|
AU2006326301B2
(en)
|
2005-12-12 |
2011-04-21 |
F. Hoffmann-La Roche Ag |
Antibodies against amyloid beta 4 with glycosylated in the variable region
|
|
US8784810B2
(en)
*
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
RU2498999C2
(ru)
*
|
2006-07-14 |
2013-11-20 |
Ац Иммуне Са |
Гуманизированное антитело к амилоиду бета
|
|
DK2074145T5
(en)
|
2006-10-02 |
2017-10-16 |
Ac Immune Sa |
HUMANIZED ANTIBODY AGAINST AMYLOID BETA
|
|
ES2535641T3
(es)
|
2007-01-18 |
2015-05-13 |
Eli Lilly & Company |
Amiloide beta Fab pegilado
|
|
US8003097B2
(en)
*
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
TWI557136B
(zh)
|
2007-06-12 |
2016-11-11 |
Ac免疫公司 |
特異性結合β-類澱粉蛋白之抗體及相關核酸分子、表現載體、細胞、組合物、套組、方法及用途
|
|
TWI516500B
(zh)
*
|
2007-06-12 |
2016-01-11 |
Ac免疫公司 |
抗β類澱粉蛋白單株抗體
|
|
ES2498040T3
(es)
*
|
2007-07-27 |
2014-09-24 |
Janssen Alzheimer Immunotherapy |
Tratamiento de enfermedades amiloidogénicas con anticuerpos anti-beta humanizados
|
|
ES2609918T3
(es)
|
2007-10-05 |
2017-04-25 |
Genentech, Inc. |
Uso de anticuerpo anti-amiloide beta en enfermedades oculares
|
|
AU2008311365B2
(en)
|
2007-10-05 |
2015-03-12 |
Ac Immune S.A. |
Humanized antibody
|
|
WO2009048631A1
(en)
|
2007-10-11 |
2009-04-16 |
University Of Tennessee Research Foundation |
PREPARATION OF PURIFIED COVALENTYLY CROSS-LINKED A β OLIGOMERS AND USES THEREOF
|
|
JO3076B1
(ar)
*
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
ES2639016T3
(es)
|
2007-11-16 |
2017-10-25 |
The Rockefeller University |
Anticuerpos específicos para la forma protofibrilar de proteína beta-amiloide
|
|
EP2237803B1
(en)
|
2007-12-28 |
2015-07-01 |
Prothena Biosciences Limited |
Treatment and prophylaxis of amyloidosis
|
|
AT506819B1
(de)
*
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
AT509611B1
(de)
|
2008-06-12 |
2012-04-15 |
Affiris Forschungs-Und Entwicklungs Gmbh |
Vakzin
|
|
CN102123726A
(zh)
|
2008-06-12 |
2011-07-13 |
阿费里斯股份公司 |
用于治疗与帕金森氏病有关的症状的化合物
|
|
AU2009266552B2
(en)
|
2008-07-01 |
2014-01-23 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vaccine against amyloid folding intermediate
|
|
US9801865B2
(en)
|
2008-09-24 |
2017-10-31 |
The United States Of America As Represented By The Department Of Veteran Affairs |
Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
|
|
EP2172485A1
(en)
*
|
2008-10-01 |
2010-04-07 |
Pierre Fabre Medicament |
Novel anti CXCR4 antibodies and their use for the treatment of cancer
|
|
JP5898495B2
(ja)
|
2008-10-06 |
2016-04-06 |
ザ ユニヴァーシティ オブ ブリティッシュ コロンビア |
ミスフォールドタンパク質エピトープを予測するための方法およびシステム
|
|
US9067981B1
(en)
*
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
US20120047601A1
(en)
*
|
2009-02-17 |
2012-02-23 |
The Regents Of The University Of California |
Method of Reducing Acetylation in Plants to Improve Biofuel Production
|
|
DK2419447T3
(en)
|
2009-04-17 |
2017-09-25 |
Immunas Pharma Inc |
ANTIBODIES THAT SPECIFICALLY BIND TO A BETA OLIGOMER AND USE THEREOF
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
JP5769316B2
(ja)
|
2009-08-06 |
2015-08-26 |
イムナス・ファーマ株式会社 |
Aβオリゴマーに特異的に結合する抗体およびその利用
|
|
JP5554528B2
(ja)
*
|
2009-09-08 |
2014-07-23 |
国立大学法人 岡山大学 |
新規アミロイドβ凝集体結合性ペプチドおよび新規アミロイドβ凝集体結合性ペプチドを用いたアミロイド病の検査方法
|
|
CA2774134A1
(en)
|
2009-09-18 |
2011-03-24 |
Probiodrug Ag |
Novel assay for the detection of amyloid beta peptides
|
|
JP5894939B2
(ja)
|
2010-02-26 |
2016-03-30 |
バイオアークティック ニューロサイエンス アーベー |
プロトフィブリル結合抗体ならびにパーキンソン病、レビー小体型認知症および他のα−シヌクレイノパチーの治療および診断方法におけるこれらの使用
|
|
SG183854A1
(en)
*
|
2010-03-03 |
2012-10-30 |
Univ British Columbia |
Oligomer-specific amyloid beta epitope and antibodies
|
|
US20110256064A1
(en)
|
2010-04-16 |
2011-10-20 |
Ac Immune, S.A. |
Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
|
|
MX337548B
(es)
|
2010-04-16 |
2016-03-10 |
Ac Immune Sa |
Nuevos compuestos para tratamiento de enfermedades asociadas con proteinas amiloides o tipo amiloide.
|
|
US9320793B2
(en)
|
2010-07-14 |
2016-04-26 |
Acumen Pharmaceuticals, Inc. |
Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42
|
|
MY164579A
(en)
|
2010-07-30 |
2018-01-15 |
Ac Immune Sa |
Safe and functional humanized antibodies
|
|
US9062101B2
(en)
|
2010-08-14 |
2015-06-23 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
CA2817973C
(en)
|
2010-10-15 |
2019-06-25 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
FR2966827B1
(fr)
*
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
EP2511296A1
(en)
|
2011-04-12 |
2012-10-17 |
Araclón Biotech, S. L. |
Antibody, kit and method for determination of amyloid peptides
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
CN104093454A
(zh)
|
2011-11-10 |
2014-10-08 |
坎格尼美国股份有限公司 |
治疗阿耳茨海默氏病的组合物和方法
|
|
EP2659908A1
(en)
|
2012-05-01 |
2013-11-06 |
Affiris AG |
Compositions
|
|
WO2014031697A2
(en)
|
2012-08-21 |
2014-02-27 |
The Institute Of Molecular Medicine |
COMPOSITIONS AND METHODS RELATED TO DISEASES ASSOCIATED WITH DEPOSITS OF AMYLOID, TAU, AND α-SYNUCLEIN
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
WO2015017900A1
(en)
|
2013-08-05 |
2015-02-12 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
CN105848671B
(zh)
|
2013-08-28 |
2019-12-13 |
艾伯维施特姆森特克斯有限责任公司 |
位点特异性抗体缀合方法和组合物
|
|
EP3102611A4
(en)
|
2014-02-03 |
2017-08-23 |
Cangene Corporation |
Humanized beta-amyloid binding molecules and uses thereof
|
|
WO2016138525A1
(en)
*
|
2015-02-27 |
2016-09-01 |
University Of Washington |
Polypeptide assemblies and methods for the production thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
JP7448174B2
(ja)
*
|
2015-11-09 |
2024-03-12 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータ中間領域エピトープおよびそれに対する立体配座選択的抗体
|
|
US10772969B2
(en)
|
2015-11-09 |
2020-09-15 |
The University Of British Columbia |
N-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
US11756650B2
(en)
*
|
2015-11-09 |
2023-09-12 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
CN108350050A
(zh)
|
2015-11-09 |
2018-07-31 |
英属哥伦比亚大学 |
淀粉样蛋白β中的表位及其构象选择性抗体
|
|
EP3374380A4
(en)
*
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
C-terminal epitopes in amyloid-beta and conformation-sensitive antibodies
|
|
HK1259324A1
(zh)
*
|
2015-11-09 |
2019-11-29 |
英属哥伦比亚大学 |
淀粉样蛋白β表位及其抗体
|
|
CN116333108A
(zh)
|
2016-07-18 |
2023-06-27 |
英属哥伦比亚大学 |
淀粉样蛋白β的抗体
|
|
US20180125920A1
(en)
*
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|