|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
WO1995006477A1
(en)
|
1993-08-31 |
1995-03-09 |
Gliatech, Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
EP0866805A1
(en)
|
1995-12-12 |
1998-09-30 |
Karolinska Innovations AB |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6043283A
(en)
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
US6071493A
(en)
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7588766B1
(en)
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
EA006606B1
(ru)
|
2000-02-24 |
2006-02-24 |
Вашингтон Юниверсити |
Гуманизированное антитело и его фрагмент, взаимодействующие с бета-амилоидным пептидом, и способы их применения
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
AR038568A1
(es)
*
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
WO2004013172A2
(en)
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
WO2010011999A2
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2005025516A2
(en)
|
2003-09-12 |
2005-03-24 |
The Regents Of The University Of California |
Monoclonal antibodies specific for conformational epitopes of prefibrillar aggregates
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
KR20050101537A
(ko)
|
2002-12-24 |
2005-10-24 |
뉴로켐 (인터내셔널) 리미티드 |
베타-아밀로이드 관련 질환의 치료를 위한 치료 제제
|
|
ES2344645T3
(es)
|
2003-02-10 |
2010-09-02 |
Applied Molecular Evolution, Inc. |
Moleculas de union al abeta.
|
|
TWI306458B
(en)
|
2003-05-30 |
2009-02-21 |
Elan Pharma Int Ltd |
Humanized antibodies that recognize beta amyloid peptide
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
CA2560618A1
(en)
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
ES2396555T3
(es)
|
2004-12-15 |
2013-02-22 |
Janssen Alzheimer Immunotherapy |
Anticuerpos que reconocen péptido beta amiloide
|
|
EP1838348B1
(en)
|
2004-12-15 |
2013-06-26 |
Janssen Alzheimer Immunotherapy |
Humanized amyloid beta antibodies for use in improving cognition
|
|
EP1676859A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
JP2008545663A
(ja)
|
2005-05-27 |
2008-12-18 |
クイーンズ ユニバーシティ アット キングストン |
タンパク質フォールディング障害の治療
|
|
JP2009516654A
(ja)
|
2005-11-10 |
2009-04-23 |
ロスキャンプ リサーチ， エルエルシー |
Ａ−ベータペプチドによる血管新生の調節
|
|
CA2632828C
(en)
|
2005-12-12 |
2012-07-10 |
F. Hoffmann-La Roche Ag |
Antibodies against amyloid beta with glycosylation in the variable region
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
HUE033466T2
(en)
|
2006-10-02 |
2017-12-28 |
Ac Immune Sa |
Humanized antibody to beta-amyloid
|
|
US20100081613A1
(en)
*
|
2006-10-11 |
2010-04-01 |
The Trustees Of Columbia University In The City Of New York |
Methods and compositions for enhancing memory
|
|
WO2008088983A1
(en)
|
2007-01-18 |
2008-07-24 |
Eli Lilly And Company |
PEGYLATED Aβ FAB
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
HRP20150086T1
(xx)
|
2007-06-12 |
2015-02-27 |
Ac Immune S.A. |
Humanizirana antitijela za beta amiloid
|
|
ES2498040T3
(es)
|
2007-07-27 |
2014-09-24 |
Janssen Alzheimer Immunotherapy |
Tratamiento de enfermedades amiloidogénicas con anticuerpos anti-beta humanizados
|
|
AU2008311366B2
(en)
|
2007-10-05 |
2015-03-12 |
Ac Immune S.A. |
Use of anti-amyloid beta antibody in ocular diseases
|
|
CA2701788C
(en)
|
2007-10-05 |
2017-06-13 |
Genentech, Inc. |
Humanized beta-amyloid antibody for treating ocular diseases
|
|
WO2009048631A1
(en)
|
2007-10-11 |
2009-04-16 |
University Of Tennessee Research Foundation |
PREPARATION OF PURIFIED COVALENTYLY CROSS-LINKED A β OLIGOMERS AND USES THEREOF
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
AU2008322523B2
(en)
*
|
2007-11-16 |
2013-10-10 |
The Rockefeller University |
Antibodies specific for the protofibril form of beta-amyloid protein
|
|
WO2009086539A2
(en)
|
2007-12-28 |
2009-07-09 |
Elan Pharmaceuticals, Inc. |
Treatment and prophylaxis of amyloidosis
|
|
AT506820B1
(de)
|
2008-06-12 |
2011-07-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzine gegen alzheimer-krankheit
|
|
AT506819B1
(de)
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
CA2723995A1
(en)
|
2008-06-12 |
2009-12-17 |
Affiris Ag |
Compounds for treating symptoms associated with parkinson's disease
|
|
US9045555B2
(en)
*
|
2008-07-01 |
2015-06-02 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vaccine against amyloid folding intermediate
|
|
EP2342220B1
(en)
|
2008-10-06 |
2021-05-12 |
The University Of British Columbia |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
JP5812418B2
(ja)
|
2009-04-17 |
2015-11-11 |
イムナス・ファーマ株式会社 |
Ａβオリゴマーに特異的に結合する抗体およびその利用
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
WO2011016238A1
(en)
|
2009-08-06 |
2011-02-10 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to a beta oligomers and use thereof
|
|
SG10201405802UA
(en)
|
2009-09-18 |
2014-11-27 |
Probiodrug Ag |
Novel assay for the detection of amyloid beta peptides
|
|
CN110655573B
(zh)
|
2010-02-26 |
2023-07-18 |
生命北极神经科学公司 |
原细纤维结合抗体及其治疗和诊断帕金森氏症、路易体痴呆和其他α-共核蛋白病的应用
|
|
WO2013071267A1
(en)
|
2011-11-10 |
2013-05-16 |
Cangene U.S., Incorporated |
Compositions and methods for treating alzheimer's disease
|
|
EP2542571B1
(en)
*
|
2010-03-03 |
2016-05-25 |
The University of British Columbia |
Oligomer-specific amyloid beta epitope and antibodies
|
|
US20110256064A1
(en)
|
2010-04-16 |
2011-10-20 |
Ac Immune, S.A. |
Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
|
|
ES2734552T3
(es)
|
2010-04-16 |
2019-12-10 |
Ac Immune Sa |
Compuestos novedosos para el tratamiento de enfermedades asociadas a proteínas amiloides o de tipo amiloide
|
|
CA2817973C
(en)
|
2010-10-15 |
2019-06-25 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
FR2966827B1
(fr)
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
EP2887955B1
(en)
|
2012-08-21 |
2020-08-19 |
Institute for Molecular Medicine, Inc. |
Compositions and methods related to diseases associated with deposits of amyloid, tau, and alpha-synuclein
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
US9908933B2
(en)
|
2013-08-05 |
2018-03-06 |
St. Vincent's Institute Of Medical Research |
Antibody therapy for amyloid beta disease
|
|
JP2016531915A
(ja)
|
2013-08-28 |
2016-10-13 |
ステムセントリックス， インコーポレイテッド |
部位特異的抗体コンジュゲーション方法および組成物
|
|
CA2938129A1
(en)
*
|
2014-02-03 |
2015-08-06 |
Cangene Corporation |
Humanized beta-amyloid binding molecules and uses thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
EP3374380A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
C-terminal epitopes in amyloid-beta and conformation-sensitive antibodies
|
|
US10774120B2
(en)
|
2015-11-09 |
2020-09-15 |
The University Of British Columbia |
Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide
|
|
EP3374382A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES
|
|
KR102964291B1
(ko)
|
2015-11-09 |
2026-05-13 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
아밀로이드 베타 에피토프 및 이에 대한 항체
|
|
US11756650B2
(en)
|
2015-11-09 |
2023-09-12 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
KR102550991B1
(ko)
|
2016-07-18 |
2023-07-04 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
아밀로이드 베타에 대한 항체
|
|
US20180125920A1
(en)
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|
|
ES2984844T3
(es)
|
2017-07-18 |
2024-10-31 |
Univ British Columbia |
Anticuerpos contra beta amiloide
|