|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
AU7642494A
(en)
|
1993-08-31 |
1995-03-22 |
Gliatech Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
EP0866805A1
(en)
|
1995-12-12 |
1998-09-30 |
Karolinska Innovations AB |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6043283A
(en)
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
US6071493A
(en)
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7588766B1
(en)
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
KR100767146B1
(ko)
|
2000-02-24 |
2007-10-15 |
워싱톤 유니버시티 |
Ａβ 펩티드를 격리시키는 인간화 항체
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2487528A1
(en)
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation
|
|
US9535076B2
(en)
|
2002-09-12 |
2017-01-03 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
JP2006512417A
(ja)
|
2002-12-24 |
2006-04-13 |
ニューロケム （インターナショナル） リミテッド |
β−アミロイド関連疾患の治療のための治療用製剤
|
|
DE602004027348D1
(de)
|
2003-02-10 |
2010-07-08 |
Applied Molecular Evolution |
Abeta-bindende moleküle
|
|
PE20050627A1
(es)
|
2003-05-30 |
2005-08-10 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
JP2007527865A
(ja)
|
2003-09-12 |
2007-10-04 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
種々の配列を有するタンパク質から形成されたアミロイドに共通の高分子量凝集中間体に特異的なモノクローナル抗体
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
CA2560618A1
(en)
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
AR052051A1
(es)
|
2004-12-15 |
2007-02-28 |
Neuralab Ltd |
Anticuerpos ab humanizados usados en mejorar la cognicion
|
|
EP1838854B1
(en)
|
2004-12-15 |
2012-10-31 |
Janssen Alzheimer Immunotherapy |
Antibodies that recognize Beta Amyloid Peptide
|
|
EP1676859A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
CA2609980C
(en)
|
2005-05-27 |
2015-10-13 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
JP2009516654A
(ja)
|
2005-11-10 |
2009-04-23 |
ロスキャンプ リサーチ， エルエルシー |
Ａ−ベータペプチドによる血管新生の調節
|
|
BRPI0619605B8
(pt)
|
2005-12-12 |
2021-05-25 |
Hoffmann La Roche |
composições compreendendo moléculas de anticorpos contra amilóide beta4 com glicosilação na região variável, usos das mesmas, método de preparação de uma molécula de anticorpo, e kit
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
CN101611054B
(zh)
|
2006-10-02 |
2013-12-25 |
Ac免疫有限公司 |
针对淀粉状蛋白β的人源化抗体
|
|
US20100081613A1
(en)
*
|
2006-10-11 |
2010-04-01 |
The Trustees Of Columbia University In The City Of New York |
Methods and compositions for enhancing memory
|
|
ES2535641T3
(es)
|
2007-01-18 |
2015-05-13 |
Eli Lilly & Company |
Amiloide beta Fab pegilado
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
SG182192A1
(en)
|
2007-06-12 |
2012-07-30 |
Ac Immune Sa |
Humanized antibodies to amyloid beta
|
|
JP5889529B2
(ja)
|
2007-07-27 |
2016-03-22 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
アミロイド原性疾患の処置
|
|
RU2542967C2
(ru)
|
2007-10-05 |
2015-02-27 |
Дженентек, Инк. |
Применение антитела против амилоида бета при глазных заболеваниях
|
|
AU2008311365B2
(en)
|
2007-10-05 |
2015-03-12 |
Ac Immune S.A. |
Humanized antibody
|
|
US20090246191A1
(en)
|
2007-10-11 |
2009-10-01 |
University Of Tennessee Research Foundation |
Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
ME01026B
(me)
*
|
2007-11-16 |
2012-10-20 |
Univ Rockefeller |
Antitijela specifična za protofibrilni oblik beta-amiloid proteina
|
|
AU2008345022B2
(en)
|
2007-12-28 |
2014-11-06 |
Prothena Biosciences Limited |
Treatment and prophylaxis of amyloidosis
|
|
AT506819B1
(de)
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
AT506820B1
(de)
|
2008-06-12 |
2011-07-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzine gegen alzheimer-krankheit
|
|
WO2009149487A2
(en)
|
2008-06-12 |
2009-12-17 |
Affiris Ag |
Compounds for treating symptoms associated with parkinson's disease
|
|
ES2397641T3
(es)
*
|
2008-07-01 |
2013-03-08 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vacuna contra el intermediario de plegado amiloide
|
|
CA2743361C
(en)
|
2008-10-06 |
2021-05-25 |
Neil R. Cashman |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
JP5812418B2
(ja)
|
2009-04-17 |
2015-11-11 |
イムナス・ファーマ株式会社 |
Ａβオリゴマーに特異的に結合する抗体およびその利用
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
JP5769316B2
(ja)
|
2009-08-06 |
2015-08-26 |
イムナス・ファーマ株式会社 |
Ａβオリゴマーに特異的に結合する抗体およびその利用
|
|
WO2011033046A1
(en)
|
2009-09-18 |
2011-03-24 |
Probiodrug Ag |
Novel assay for the detection of amyloid beta peptides
|
|
JP5894939B2
(ja)
|
2010-02-26 |
2016-03-30 |
バイオアークティック ニューロサイエンス アーベー |
プロトフィブリル結合抗体ならびにパーキンソン病、レビー小体型認知症および他のα−シヌクレイノパチーの治療および診断方法におけるこれらの使用
|
|
RU2644335C2
(ru)
|
2010-03-03 |
2018-02-08 |
Зе Юниверсити Оф Бритиш Коламбия |
Эпитоп, специфичный к олигомеру амилоида бета, и антитела
|
|
RU2603008C2
(ru)
|
2010-04-16 |
2016-11-20 |
Ац Иммуне С.А. |
Новые соединения для лечения заболеваний, связанных с амилоидными или амилоидоподобными белками
|
|
US20110256064A1
(en)
|
2010-04-16 |
2011-10-20 |
Ac Immune, S.A. |
Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
|
|
CA2817973C
(en)
|
2010-10-15 |
2019-06-25 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
FR2966827B1
(fr)
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
CA2855669A1
(en)
*
|
2011-11-10 |
2013-05-16 |
Cangene U.S., Incorporated |
Compositions and methods for treating alzheimer's disease
|
|
AU2013305848B2
(en)
|
2012-08-21 |
2020-10-15 |
Institute For Molecular Medicine, Inc. |
Compositions and methods related to diseases associated with deposits of amyloid, Tau, and alpha-synuclein
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
AU2014305658A1
(en)
|
2013-08-05 |
2016-02-11 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
PE20160674A1
(es)
|
2013-08-28 |
2016-07-21 |
Stemcentrx Inc |
Metodos de conjugacion de anticuerpos especificos de sitio y composiciones
|
|
WO2015113169A1
(en)
*
|
2014-02-03 |
2015-08-06 |
Cnj Holdings, Inc. |
Humanized beta-amyloid binding molecules and uses thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
JP2019505165A
(ja)
|
2015-11-09 |
2019-02-28 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータのｃ末端エピトープおよびそれに対する立体配座選択的抗体
|
|
US20180326027A1
(en)
|
2015-11-09 |
2018-11-15 |
The University Of British Columbia |
Epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
AU2016354688B2
(en)
|
2015-11-09 |
2021-12-16 |
The University Of British Columbia |
Epitopes in Amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
CA3004498A1
(en)
|
2015-11-09 |
2017-05-18 |
Neil R. Cashman |
Amyloid beta epitopes and antibodies thereto
|
|
CA3004593A1
(en)
|
2015-11-09 |
2017-05-18 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
EP3484919A4
(en)
|
2016-07-18 |
2020-03-04 |
The University of British Columbia |
ANTI-BETA-AMYLOID ANTIBODIES
|
|
US20180125920A1
(en)
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|
|
JP7330164B2
(ja)
|
2017-07-18 |
2023-08-21 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータに対する抗体
|