JP2022502369A5 - - Google Patents

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Publication number
JP2022502369A5
JP2022502369A5 JP2021516452A JP2021516452A JP2022502369A5 JP 2022502369 A5 JP2022502369 A5 JP 2022502369A5 JP 2021516452 A JP2021516452 A JP 2021516452A JP 2021516452 A JP2021516452 A JP 2021516452A JP 2022502369 A5 JP2022502369 A5 JP 2022502369A5
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JP
Japan
Prior art keywords
cdr
sequence
seq
amino acid
acid sequence
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Application number
JP2021516452A
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English (en)
Japanese (ja)
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JP7719713B2 (ja
JP2022502369A (ja
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Priority claimed from PCT/CA2019/051434 external-priority patent/WO2020073121A1/en
Publication of JP2022502369A publication Critical patent/JP2022502369A/ja
Publication of JP2022502369A5 publication Critical patent/JP2022502369A5/ja
Application granted granted Critical
Publication of JP7719713B2 publication Critical patent/JP7719713B2/ja
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JP2021516452A 2018-10-07 2019-10-07 α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法 Active JP7719713B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862742408P 2018-10-07 2018-10-07
US62/742,408 2018-10-07
US201862780599P 2018-12-17 2018-12-17
US62/780,599 2018-12-17
US201962820701P 2019-03-19 2019-03-19
US62/820,701 2019-03-19
US201962864060P 2019-06-20 2019-06-20
US62/864,060 2019-06-20
PCT/CA2019/051434 WO2020073121A1 (en) 2018-10-07 2019-10-07 Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof

Publications (3)

Publication Number Publication Date
JP2022502369A JP2022502369A (ja) 2022-01-11
JP2022502369A5 true JP2022502369A5 (enExample) 2022-10-20
JP7719713B2 JP7719713B2 (ja) 2025-08-06

Family

ID=70163645

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021516452A Active JP7719713B2 (ja) 2018-10-07 2019-10-07 α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法

Country Status (6)

Country Link
US (2) US12404321B2 (enExample)
EP (1) EP3861015A4 (enExample)
JP (1) JP7719713B2 (enExample)
AU (1) AU2019356804B2 (enExample)
CA (1) CA3148562A1 (enExample)
WO (1) WO2020073121A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3051839A1 (en) 2017-02-17 2018-08-23 Bristol-Myers Squibb Company Antibodies to alpha-synuclein and uses thereof
WO2025236075A1 (en) * 2024-05-07 2025-11-20 The University Of British Columbia Immunogenic compositions for synucleinopathies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358331B2 (en) 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
AT506535B1 (de) 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
CN102112488A (zh) 2008-07-01 2011-06-29 由卫生福利和体育大臣代表的荷兰王国 抗淀粉样折叠中间体的疫苗
HRP20160385T1 (hr) * 2009-03-09 2016-05-06 Ramot At Tel-Aviv University Ltd. Pripravci za prevenciju i liječenje neurodegenerativnih bolesti
JP2013500326A (ja) * 2009-07-30 2013-01-07 ファイザー バクシーンズ エルエルシー 抗原性タウペプチドおよびその使用
JP6190113B2 (ja) * 2010-03-03 2017-08-30 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア オリゴマー特異アミロイドベータエピトープおよび抗体
CN102504016B (zh) * 2011-12-08 2014-05-28 清华大学 淀粉样蛋白纤维性寡聚体构象型抗原表位多肽及其应用
US9534044B2 (en) 2013-02-28 2017-01-03 United Arab Emirates University Alpha-synuclein antibodies and uses thereof
CA3004493A1 (en) * 2015-11-09 2017-05-18 The University Of British Columiba C-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
EP3448874A4 (en) * 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
CN109476729A (zh) * 2016-07-18 2019-03-15 英属哥伦比亚大学 淀粉样蛋白β的抗体
US10364286B2 (en) 2016-12-22 2019-07-30 H. Lundbeck A/S Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation

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