JP2020522475A5 - - Google Patents
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- JP2020522475A5 JP2020522475A5 JP2019565224A JP2019565224A JP2020522475A5 JP 2020522475 A5 JP2020522475 A5 JP 2020522475A5 JP 2019565224 A JP2019565224 A JP 2019565224A JP 2019565224 A JP2019565224 A JP 2019565224A JP 2020522475 A5 JP2020522475 A5 JP 2020522475A5
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- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- chain variable
- variable region
- Prior art date
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762512647P | 2017-05-30 | 2017-05-30 | |
| US62/512,647 | 2017-05-30 | ||
| US201762570582P | 2017-10-10 | 2017-10-10 | |
| US62/570,582 | 2017-10-10 | ||
| US201762595866P | 2017-12-07 | 2017-12-07 | |
| US62/595,866 | 2017-12-07 | ||
| PCT/CA2018/050634 WO2018218352A1 (en) | 2017-05-30 | 2018-05-30 | Epitopes in the rna recognition motif 1 (rrm1) of tdp-43 and misfolding-selective antibodies thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020522475A JP2020522475A (ja) | 2020-07-30 |
| JP2020522475A5 true JP2020522475A5 (enExample) | 2021-07-26 |
| JP7761373B2 JP7761373B2 (ja) | 2025-10-28 |
Family
ID=64454301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565224A Active JP7761373B2 (ja) | 2017-05-30 | 2018-05-30 | Ｔｄｐ－４３のｒｎａ認識モチーフ１（ｒｒｍ１）中のエピトープ、およびそれらに対するミスフォールディング選択的抗体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11214613B2 (enExample) |
| EP (1) | EP3634987A4 (enExample) |
| JP (1) | JP7761373B2 (enExample) |
| CA (1) | CA3064785A1 (enExample) |
| WO (1) | WO2018218352A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114008073B (zh) * | 2019-05-23 | 2025-08-12 | Ac免疫有限公司 | 抗tdp-43结合分子及其用途 |
| EP3976793A4 (en) * | 2019-05-27 | 2023-06-21 | The University of British Columbia | CONFORMATION-SPECIFIC EPITOPES IN TAU, ANTIBODIES AGAINST IT AND METHODS RELATED THERETO |
| US20240050529A1 (en) | 2019-10-07 | 2024-02-15 | University Of Virginia Patent Foundation | Modulating lymphatic vessels in neurological disease |
| US20230067811A1 (en) | 2020-01-24 | 2023-03-02 | University Of Virginia Patent Foundation | Modulating lymphatic vessels in neurological disease |
| CA3231484A1 (en) | 2021-10-01 | 2023-04-06 | Qinwen Mao | Pathologic tdp-43 as a biomarker for the diagnosis of tdp-43 proteinopathy |
| IL316153A (en) * | 2022-04-08 | 2024-12-01 | Ac Immune Sa | Anti-tdp-43 binding molecules |
| WO2025035133A1 (en) * | 2023-08-10 | 2025-02-13 | Board Of Regents, The University Of Texas System | Bmp-7 antibody compositions & methods for treating cancer |
| WO2026132413A1 (en) | 2024-12-20 | 2026-06-25 | Bioarctic Ab | Antibody against tdp-43 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997012975A1 (en) | 1995-10-02 | 1997-04-10 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | An epithelial protein and dna thereof for use in early cancer detection |
| US6472367B1 (en) * | 1998-05-05 | 2002-10-29 | Adherex Technologies, Inc. | Compounds and methods for modulating OB-cadherin mediated cell adhesion |
| AT506819B1 (de) * | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| EP2342220B1 (en) | 2008-10-06 | 2021-05-12 | The University Of British Columbia | Methods and systems for predicting misfolded protein epitopes |
| GB0922435D0 (en) | 2009-12-22 | 2010-02-03 | Ucb Pharma Sa | Method |
| EP3453717A1 (en) * | 2010-07-21 | 2019-03-13 | Eastern Virginia Medical School | Peptide compounds to regulate the complement system |
| CA2853412C (en) | 2011-10-28 | 2021-05-04 | University Of Zurich | Tdp-43 specific binding molecules |
| US9428575B2 (en) * | 2012-12-31 | 2016-08-30 | Development Center For Biotechnology | Anti-granulysin antibodies and methods of use thereof |
| WO2016053610A1 (en) | 2014-10-03 | 2016-04-07 | Academia Sinica | Antibodies against pathological forms of tdp-43 and uses thereof |
| CA2874083C (en) | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| US11756650B2 (en) | 2015-11-09 | 2023-09-12 | The University Of British Columbia | Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing |
| US20180125920A1 (en) * | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
-
2018
- 2018-05-30 JP JP2019565224A patent/JP7761373B2/ja active Active
- 2018-05-30 CA CA3064785A patent/CA3064785A1/en active Pending
- 2018-05-30 EP EP18810255.2A patent/EP3634987A4/en active Pending
- 2018-05-30 WO PCT/CA2018/050634 patent/WO2018218352A1/en not_active Ceased
- 2018-05-30 US US16/616,832 patent/US11214613B2/en active Active
-
2021
- 2021-12-03 US US17/541,812 patent/US20220162293A1/en active Pending
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