JP2017524362A5 - - Google Patents

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Publication number
JP2017524362A5
JP2017524362A5 JP2017505099A JP2017505099A JP2017524362A5 JP 2017524362 A5 JP2017524362 A5 JP 2017524362A5 JP 2017505099 A JP2017505099 A JP 2017505099A JP 2017505099 A JP2017505099 A JP 2017505099A JP 2017524362 A5 JP2017524362 A5 JP 2017524362A5
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JP
Japan
Prior art keywords
antibody
binding fragment
seq
αklotho
cdr
Prior art date
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JP2017505099A
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English (en)
Japanese (ja)
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JP2017524362A (ja
JP6612324B2 (ja
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Priority claimed from PCT/CA2015/050728 external-priority patent/WO2016015162A1/en
Publication of JP2017524362A publication Critical patent/JP2017524362A/ja
Publication of JP2017524362A5 publication Critical patent/JP2017524362A5/ja
Application granted granted Critical
Publication of JP6612324B2 publication Critical patent/JP6612324B2/ja
Expired - Fee Related legal-status Critical Current
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JP2017505099A 2014-07-31 2015-07-31 αＫｌｏｔｈｏに対して高親和性を有する抗体 Expired - Fee Related JP6612324B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462031477P 2014-07-31 2014-07-31
US62/031,477 2014-07-31
PCT/CA2015/050728 WO2016015162A1 (en) 2014-07-31 2015-07-31 ANTIBODIES WITH HIGH AFFINITY FOR αKLOTHO

Publications (3)

Publication Number Publication Date
JP2017524362A JP2017524362A (ja) 2017-08-31
JP2017524362A5 true JP2017524362A5 (enExample) 2018-09-06
JP6612324B2 JP6612324B2 (ja) 2019-11-27

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ID=55216538

Family Applications (1)

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JP2017505099A Expired - Fee Related JP6612324B2 (ja) 2014-07-31 2015-07-31 αＫｌｏｔｈｏに対して高親和性を有する抗体

Country Status (5)

Country Link
US (2) US10228374B2 (enExample)
EP (1) EP3174986A4 (enExample)
JP (1) JP6612324B2 (enExample)
CA (1) CA2955039C (enExample)
WO (1) WO2016015162A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6682641B2 (ja) * 2016-02-03 2020-04-15 ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント αＫｌｏｔｈｏに対する抗体およびＥＬＩＳＡ
AU2017324983B2 (en) * 2016-09-07 2025-03-20 Saksin Lifesciences Pvt Ltd Synthetic antibodies against VEGF and their uses
EP3665705B1 (en) 2017-08-08 2024-12-18 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
JP7290340B2 (ja) * 2017-12-06 2023-06-13 クロトー セラピューティクス インコーポレイテッド クロトータンパク質レベルを評価および改善するための製品および方法
WO2019133665A2 (en) * 2017-12-29 2019-07-04 Yale University Methods for measuring renalase
EP3732204A4 (en) 2017-12-29 2022-01-19 Yale University ANTI-RENALASE ANTIBODIES TO TREAT AND PREVENT DISEASES AND DISORDERS
WO2020047505A1 (en) * 2018-08-30 2020-03-05 The Uab Research Foundation Production and detection of bioactive soluble klotho protein
CN117805395A (zh) * 2023-12-29 2024-04-02 上海药明合联生物技术有限公司 一种比较抗体偶联药物和抗体的亲和力的方法及其应用
CN120943965B (zh) * 2025-10-16 2026-02-06 广东医科大学附属医院 一种αKL蛋白抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2087997T3 (es) 1990-01-12 1996-08-01 Cell Genesys Inc Generacion de anticuerpos xenogenicos.
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO2013184218A1 (en) 2012-06-05 2013-12-12 Msm Protein Technologies Human monoclonal antibodies against human chemokine receptor ccr6
CN107614020A (zh) 2015-03-18 2018-01-19 免疫生化公司 靶向细胞内肿瘤相关抗原的用于治疗癌症的缀合物
JP6682641B2 (ja) 2016-02-03 2020-04-15 ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント αＫｌｏｔｈｏに対する抗体およびＥＬＩＳＡ

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