JP2018516853A5 - - Google Patents
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- JP2018516853A5 JP2018516853A5 JP2017551294A JP2017551294A JP2018516853A5 JP 2018516853 A5 JP2018516853 A5 JP 2018516853A5 JP 2017551294 A JP2017551294 A JP 2017551294A JP 2017551294 A JP2017551294 A JP 2017551294A JP 2018516853 A5 JP2018516853 A5 JP 2018516853A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding fragment
- seq
- antibody
- isolated antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562140913P | 2015-03-31 | 2015-03-31 | |
| US62/140,913 | 2015-03-31 | ||
| PCT/EP2016/056973 WO2016156440A1 (en) | 2015-03-31 | 2016-03-30 | A novel il33 form, mutated forms of il33, antibodies, assays and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020178437A Division JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018516853A JP2018516853A (ja) | 2018-06-28 |
| JP2018516853A5 true JP2018516853A5 (enExample) | 2019-05-16 |
| JP6862351B2 JP6862351B2 (ja) | 2021-04-21 |
Family
ID=55640748
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551294A Active JP6862351B2 (ja) | 2015-03-31 | 2016-03-30 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
| JP2020178437A Pending JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
| JP2023173336A Pending JP2024001166A (ja) | 2015-03-31 | 2023-10-05 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020178437A Pending JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
| JP2023173336A Pending JP2024001166A (ja) | 2015-03-31 | 2023-10-05 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US10668150B2 (enExample) |
| EP (3) | EP3733701A1 (enExample) |
| JP (3) | JP6862351B2 (enExample) |
| KR (1) | KR102261618B1 (enExample) |
| CN (1) | CN108064236B (enExample) |
| AU (3) | AU2016239331C1 (enExample) |
| CA (1) | CA2982400C (enExample) |
| CL (2) | CL2017002433A1 (enExample) |
| CO (1) | CO2017010753A2 (enExample) |
| CY (1) | CY1123925T1 (enExample) |
| DK (1) | DK3277717T3 (enExample) |
| ES (1) | ES2886114T3 (enExample) |
| HR (1) | HRP20210096T1 (enExample) |
| HU (1) | HUE053097T2 (enExample) |
| IL (2) | IL254551A0 (enExample) |
| LT (1) | LT3277717T (enExample) |
| MX (1) | MX387295B (enExample) |
| MY (1) | MY190209A (enExample) |
| NZ (1) | NZ736026A (enExample) |
| PL (1) | PL3277717T3 (enExample) |
| PT (1) | PT3277717T (enExample) |
| RS (1) | RS61438B1 (enExample) |
| RU (1) | RU2736299C2 (enExample) |
| SG (1) | SG11201707593UA (enExample) |
| SI (1) | SI3277717T1 (enExample) |
| SM (1) | SMT202100086T1 (enExample) |
| TW (1) | TWI721973B (enExample) |
| WO (1) | WO2016156440A1 (enExample) |
| ZA (1) | ZA201707355B (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3088517B1 (en) | 2013-12-26 | 2023-11-01 | Mitsubishi Tanabe Pharma Corporation | Human anti-il-33 neutralizing monoclonal antibody |
| AU2015346460A1 (en) | 2014-11-10 | 2017-03-23 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN107109494B (zh) | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| CN108064236B (zh) * | 2015-03-31 | 2021-12-10 | 免疫医疗有限公司 | 新颖的il33形式、il33的突变形式、抗体、测定及其使用方法 |
| RU2740309C2 (ru) | 2016-04-27 | 2021-01-13 | Пфайзер Инк. | Антитела против il-33, композиции, способы и их применение |
| JOP20190093A1 (ar) | 2016-10-28 | 2019-04-25 | Lilly Co Eli | أجسام مضادة لـ il-33 واستخداماتها |
| TWI857389B (zh) | 2016-12-01 | 2024-10-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| RS66900B1 (sr) | 2016-12-21 | 2025-07-31 | Cephalon Llc | Antitela koja se specifično vezuju za humani il-15 i njihova upotreba |
| JP7321939B2 (ja) | 2017-04-13 | 2023-08-07 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｉｌ３３及びｉｌ１ｒｌ１をコードする遺伝子にリスクアレルを有する患者の炎症性肺疾患の処置及び阻害 |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| AU2018325645C1 (en) | 2017-08-31 | 2025-01-30 | Hyogo College Of Medicine | IL-33 antagonist-containing therapeutic agent for endometriosis |
| CN107973849B (zh) * | 2017-11-30 | 2020-07-28 | 畜科生物工程有限公司 | 一种用于增强猪疫苗免疫效果的蛋白质及其应用 |
| WO2019183375A1 (en) * | 2018-03-22 | 2019-09-26 | Eureka Therapeutics, Inc. | Antibody agents specifically recognizing monocarboxylate transporter 4 and uses thereof |
| IL277890B2 (en) | 2018-04-11 | 2024-03-01 | Regeneron Pharma | Methods for quantifying il-33 |
| EP3851121A4 (en) * | 2018-09-14 | 2022-06-08 | Mitsubishi Tanabe Pharma Corporation | PHARMACEUTICAL COMPOSITION CONTAINING HUMAN MONOCLONAL ANTI-IL-33 ANTIBODIES |
| CN111434687B (zh) * | 2019-01-15 | 2022-03-11 | 南京赛新生物科技有限公司 | 一种抗体及其应用 |
| CN111434680B (zh) * | 2019-01-15 | 2021-11-23 | 南京赛新生物科技有限公司 | 一种与il33相关疾病的抗原表位肽及其应用 |
| CN112300265B (zh) * | 2019-07-29 | 2022-09-27 | 百奥赛图(北京)医药科技股份有限公司 | Il33基因人源化的非人动物的构建方法和应用 |
| CN110567861B (zh) * | 2019-09-09 | 2021-12-21 | 浙江普罗亭健康科技有限公司 | 基于质谱流式检测技术筛查具有免疫原性抗原肽的试剂盒及检测方法 |
| IL292443A (en) | 2019-11-04 | 2022-06-01 | Medimmune Ltd | Methods for using IL-33 antagonists |
| JP2023501316A (ja) * | 2019-11-04 | 2023-01-18 | メドイミューン・リミテッド | 腎機能障害を治療するための抗ｉｌ－３３治療薬 |
| JP7767298B2 (ja) | 2020-03-13 | 2025-11-11 | ジェネンテック， インコーポレイテッド | 抗インターロイキン－３３抗体及びその使用 |
| CN115315527A (zh) * | 2020-03-13 | 2022-11-08 | 免疫医疗有限公司 | 用于治疗il33中存在风险等位基因的受试者的治疗方法 |
| IL296853A (en) * | 2020-04-06 | 2022-11-01 | Medimmune Ltd | Treatment of acute respiratory distress syndrome with il-33 axis binding antagonists |
| EP4149521A1 (en) * | 2020-05-11 | 2023-03-22 | MedImmune Limited | Formulations of anti-il-33 antibodies |
| AU2021271960A1 (en) * | 2020-05-12 | 2023-02-02 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | ST2 antigen binding protein |
| CN111378037B (zh) * | 2020-06-01 | 2020-09-01 | 南京诺艾新生物技术有限公司 | 一种抗hIL-33人源化单抗及其应用 |
| WO2022175217A1 (en) | 2021-02-18 | 2022-08-25 | F. Hoffmann-La Roche Ag | Method for resolving complex, multistep antibody interactions |
| CN113234157B (zh) * | 2021-07-09 | 2021-09-21 | 上海普铭生物科技有限公司 | 亲和力成熟的人源化抗人il-33单克隆抗体及其应用 |
| IL310926B2 (en) * | 2021-08-27 | 2025-04-01 | Medimmune Ltd | Treatment of chronic obstructive pulmonary disease with anti-interleukin-33 antibody |
| JP2024544885A (ja) * | 2021-11-10 | 2024-12-05 | ジェネンテック， インコーポレイテッド | 抗インターロイキン－３３抗体及びその使用 |
| TW202402790A (zh) | 2022-03-25 | 2024-01-16 | 英商梅迪繆思有限公司 | 減少呼吸系統感染之方法 |
| IL319071A (en) | 2022-08-19 | 2025-04-01 | Medimmune Ltd | Treatment of acute respiratory failure |
| US20260056210A1 (en) | 2022-08-19 | 2026-02-26 | Medimmune Limited | Method of selecting patients for treatment with an il-33 axis antagonist |
| WO2024038187A1 (en) | 2022-08-19 | 2024-02-22 | Medimmune Limited | Assay for detection of il-33 |
| TW202423972A (zh) | 2022-08-26 | 2024-06-16 | 英商梅迪繆思有限公司 | 使用抗介白素－３３抗體的氣喘治療 |
| EP4694940A1 (en) | 2023-04-12 | 2026-02-18 | Astrazeneca AB | Steap2-targeted compounds and use thereof |
| TW202540170A (zh) * | 2023-11-27 | 2025-10-16 | 英商葛蘭素史密斯克藍智慧財產發展有限公司 | 抗原結合蛋白 |
| WO2025120567A1 (en) | 2023-12-07 | 2025-06-12 | Medimmune Limited | Method of treatment of asthma |
| WO2025210099A1 (en) | 2024-04-04 | 2025-10-09 | Medimmune Limited | Method of treatment and selecting a subject |
| WO2025242619A1 (en) | 2024-05-20 | 2025-11-27 | Medimmune Limited | Treatment for mucus plugging |
| WO2025242618A1 (en) | 2024-05-20 | 2025-11-27 | Medimmune Limited | Bronchiectasis treatment |
| WO2025252012A1 (en) * | 2024-06-03 | 2025-12-11 | Fbd Biologics Limited | Engineered il-7 variants and methods of use thereof |
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| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| DE3668186D1 (de) | 1985-04-01 | 1990-02-15 | Celltech Ltd | Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert. |
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| CN108064236B (zh) * | 2015-03-31 | 2021-12-10 | 免疫医疗有限公司 | 新颖的il33形式、il33的突变形式、抗体、测定及其使用方法 |
-
2016
- 2016-03-30 CN CN201680019480.3A patent/CN108064236B/zh active Active
- 2016-03-30 SM SM20210086T patent/SMT202100086T1/it unknown
- 2016-03-30 JP JP2017551294A patent/JP6862351B2/ja active Active
- 2016-03-30 EP EP20169253.0A patent/EP3733701A1/en not_active Ceased
- 2016-03-30 US US15/562,228 patent/US10668150B2/en active Active
- 2016-03-30 NZ NZ736026A patent/NZ736026A/en unknown
- 2016-03-30 EP EP23219513.1A patent/EP4374916A3/en active Pending
- 2016-03-30 SI SI201631069T patent/SI3277717T1/sl unknown
- 2016-03-30 SG SG11201707593UA patent/SG11201707593UA/en unknown
- 2016-03-30 MY MYPI2017703606A patent/MY190209A/en unknown
- 2016-03-30 PL PL16712353T patent/PL3277717T3/pl unknown
- 2016-03-30 WO PCT/EP2016/056973 patent/WO2016156440A1/en not_active Ceased
- 2016-03-30 KR KR1020177030936A patent/KR102261618B1/ko active Active
- 2016-03-30 RS RS20210171A patent/RS61438B1/sr unknown
- 2016-03-30 AU AU2016239331A patent/AU2016239331C1/en active Active
- 2016-03-30 LT LTEP16712353.8T patent/LT3277717T/lt unknown
- 2016-03-30 RU RU2017134909A patent/RU2736299C2/ru active
- 2016-03-30 PT PT167123538T patent/PT3277717T/pt unknown
- 2016-03-30 ES ES16712353T patent/ES2886114T3/es active Active
- 2016-03-30 HU HUE16712353A patent/HUE053097T2/hu unknown
- 2016-03-30 MX MX2017012616A patent/MX387295B/es unknown
- 2016-03-30 HR HRP20210096TT patent/HRP20210096T1/hr unknown
- 2016-03-30 EP EP16712353.8A patent/EP3277717B1/en active Active
- 2016-03-30 CA CA2982400A patent/CA2982400C/en active Active
- 2016-03-30 DK DK16712353.8T patent/DK3277717T3/da active
- 2016-03-31 TW TW105110432A patent/TWI721973B/zh active
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2017
- 2017-09-18 IL IL254551A patent/IL254551A0/en unknown
- 2017-09-27 CL CL2017002433A patent/CL2017002433A1/es unknown
- 2017-10-23 CO CONC2017/0010753A patent/CO2017010753A2/es unknown
- 2017-10-30 ZA ZA2017/07355A patent/ZA201707355B/en unknown
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2019
- 2019-10-17 AU AU2019250213A patent/AU2019250213B2/en active Active
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2020
- 2020-04-10 US US16/845,121 patent/US11738081B2/en active Active
- 2020-09-02 CL CL2020002269A patent/CL2020002269A1/es unknown
- 2020-10-23 JP JP2020178437A patent/JP2021038226A/ja active Pending
-
2021
- 2021-01-10 IL IL280045A patent/IL280045B/en unknown
- 2021-02-17 CY CY20211100134T patent/CY1123925T1/el unknown
- 2021-10-25 AU AU2021257881A patent/AU2021257881B2/en active Active
-
2023
- 2023-07-05 US US18/346,884 patent/US20240016929A1/en active Pending
- 2023-10-05 JP JP2023173336A patent/JP2024001166A/ja active Pending
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