JP2018516853A5 - - Google Patents
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- Publication number
- JP2018516853A5 JP2018516853A5 JP2017551294A JP2017551294A JP2018516853A5 JP 2018516853 A5 JP2018516853 A5 JP 2018516853A5 JP 2017551294 A JP2017551294 A JP 2017551294A JP 2017551294 A JP2017551294 A JP 2017551294A JP 2018516853 A5 JP2018516853 A5 JP 2018516853A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding fragment
- seq
- antibody
- isolated antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562140913P | 2015-03-31 | 2015-03-31 | |
| US62/140,913 | 2015-03-31 | ||
| PCT/EP2016/056973 WO2016156440A1 (en) | 2015-03-31 | 2016-03-30 | A novel il33 form, mutated forms of il33, antibodies, assays and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020178437A Division JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018516853A JP2018516853A (ja) | 2018-06-28 |
| JP2018516853A5 true JP2018516853A5 (enExample) | 2019-05-16 |
| JP6862351B2 JP6862351B2 (ja) | 2021-04-21 |
Family
ID=55640748
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551294A Active JP6862351B2 (ja) | 2015-03-31 | 2016-03-30 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
| JP2020178437A Pending JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020178437A Pending JP2021038226A (ja) | 2015-03-31 | 2020-10-23 | 新規ｉｌ３３型、変異型のｉｌ３３、抗体、アッセイ及びそれらの使用方法 |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US10668150B2 (enExample) |
| EP (3) | EP3733701A1 (enExample) |
| JP (2) | JP6862351B2 (enExample) |
| KR (1) | KR102261618B1 (enExample) |
| CN (1) | CN108064236B (enExample) |
| AU (3) | AU2016239331C1 (enExample) |
| CA (1) | CA2982400C (enExample) |
| CL (2) | CL2017002433A1 (enExample) |
| CO (1) | CO2017010753A2 (enExample) |
| CY (1) | CY1123925T1 (enExample) |
| DK (1) | DK3277717T3 (enExample) |
| ES (1) | ES2886114T3 (enExample) |
| HR (1) | HRP20210096T1 (enExample) |
| HU (1) | HUE053097T2 (enExample) |
| IL (2) | IL254551A0 (enExample) |
| LT (1) | LT3277717T (enExample) |
| MX (1) | MX387295B (enExample) |
| MY (1) | MY190209A (enExample) |
| NZ (1) | NZ736026A (enExample) |
| PL (1) | PL3277717T3 (enExample) |
| PT (1) | PT3277717T (enExample) |
| RS (1) | RS61438B1 (enExample) |
| RU (1) | RU2736299C2 (enExample) |
| SG (1) | SG11201707593UA (enExample) |
| SI (1) | SI3277717T1 (enExample) |
| SM (1) | SMT202100086T1 (enExample) |
| TW (1) | TWI721973B (enExample) |
| WO (1) | WO2016156440A1 (enExample) |
| ZA (1) | ZA201707355B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE064292T2 (hu) | 2013-12-26 | 2024-03-28 | Mitsubishi Tanabe Pharma Corp | Humán anti-IL-33 semlegesítõ monoklonális antitest |
| US11708608B2 (en) | 2014-11-10 | 2023-07-25 | Genentech, Inc. | Therapeutic and diagnostic methods for IL-33-mediated disorders |
| JP6929771B2 (ja) | 2014-11-10 | 2021-09-01 | ジェネンテック， インコーポレイテッド | 抗インターロイキン−３３抗体及びその使用 |
| SG11201808693WA (en) | 2016-04-27 | 2018-11-29 | Pfizer | Anti-il-33 antibodies, compositions, methods and uses thereof |
| JOP20190093A1 (ar) | 2016-10-28 | 2019-04-25 | Lilly Co Eli | أجسام مضادة لـ il-33 واستخداماتها |
| TWI784988B (zh) | 2016-12-01 | 2022-12-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| HRP20250482T1 (hr) | 2016-12-21 | 2025-06-20 | Cephalon Llc | Protutijela koja se specifično vežu na ljudski il-15 i njihove uporabe |
| MX2019012171A (es) | 2017-04-13 | 2019-11-25 | Regeneron Pharma | Tratamiento e inhibicion de enfermedades pulmonares inflamatorias en pacientes que tienen alelos de riesgo en los genes que codifican la il33 e il1rl1. |
| WO2018231827A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| WO2019045075A1 (ja) | 2017-08-31 | 2019-03-07 | 田辺三菱製薬株式会社 | Ｉｌ－３３アンタゴニストを含む子宮内膜症治療剤 |
| CN107973849B (zh) * | 2017-11-30 | 2020-07-28 | 畜科生物工程有限公司 | 一种用于增强猪疫苗免疫效果的蛋白质及其应用 |
| WO2019183375A1 (en) * | 2018-03-22 | 2019-09-26 | Eureka Therapeutics, Inc. | Antibody agents specifically recognizing monocarboxylate transporter 4 and uses thereof |
| IL307286B2 (en) | 2018-04-11 | 2026-03-01 | Regeneron Pharma | Methods and compositions for quantifying il-33 |
| CN120267816A (zh) * | 2018-09-14 | 2025-07-08 | 田边三菱制药株式会社 | 含有人抗il-33单克隆抗体的医药用组合物 |
| CN111434687B (zh) * | 2019-01-15 | 2022-03-11 | 南京赛新生物科技有限公司 | 一种抗体及其应用 |
| CN111434680B (zh) * | 2019-01-15 | 2021-11-23 | 南京赛新生物科技有限公司 | 一种与il33相关疾病的抗原表位肽及其应用 |
| US20220272953A1 (en) * | 2019-07-29 | 2022-09-01 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric il33 |
| CN110567861B (zh) * | 2019-09-09 | 2021-12-21 | 浙江普罗亭健康科技有限公司 | 基于质谱流式检测技术筛查具有免疫原性抗原肽的试剂盒及检测方法 |
| KR20220092927A (ko) * | 2019-11-04 | 2022-07-04 | 메디뮨 리미티드 | 신장 장애를 치료하기 위한 항 il-33 치료제 |
| JP7843701B2 (ja) * | 2019-11-04 | 2026-04-10 | メディミューン リミテッド | Ｉｌ－３３アンタゴニストの使用方法 |
| JP2023516497A (ja) | 2020-03-13 | 2023-04-19 | メドイミューン・リミテッド | Ｉｌ３３にリスクアレルを有する対象を治療するための治療方法 |
| EP4118114A1 (en) | 2020-03-13 | 2023-01-18 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN115867575A (zh) * | 2020-04-06 | 2023-03-28 | 免疫医疗有限公司 | 用il-33轴结合拮抗剂治疗急性呼吸窘迫综合征 |
| WO2021228760A1 (en) * | 2020-05-11 | 2021-11-18 | Medimmune Limited | Formulations of anti-il-33 antibodies |
| CN121914272A (zh) * | 2020-05-12 | 2026-04-24 | 正大天晴药业集团股份有限公司 | St2抗原结合蛋白 |
| CN111378037B (zh) * | 2020-06-01 | 2020-09-01 | 南京诺艾新生物技术有限公司 | 一种抗hIL-33人源化单抗及其应用 |
| CN116888473A (zh) * | 2021-02-18 | 2023-10-13 | 豪夫迈·罗氏有限公司 | 用于解析复杂、多步骤抗体相互作用的方法 |
| CN113234157B (zh) * | 2021-07-09 | 2021-09-21 | 上海普铭生物科技有限公司 | 亲和力成熟的人源化抗人il-33单克隆抗体及其应用 |
| ES2991847T3 (es) | 2021-08-27 | 2024-12-05 | Medimmune Ltd | Tratamiento de enfermedad pulmonar obstructiva crónica con un anticuerpo anti-interleucina-33 |
| WO2023086807A1 (en) * | 2021-11-10 | 2023-05-19 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| TW202402790A (zh) | 2022-03-25 | 2024-01-16 | 英商梅迪繆思有限公司 | 減少呼吸系統感染之方法 |
| KR20250094657A (ko) | 2022-08-19 | 2025-06-25 | 메디뮨 리미티드 | 급성 호흡부전의 치료 |
| TW202423973A (zh) | 2022-08-19 | 2024-06-16 | 英商梅迪繆思有限公司 | 選擇患者以用ｉｌ—３３軸拮抗劑進行治療之方法 |
| CN119894926A (zh) | 2022-08-19 | 2025-04-25 | 免疫医疗有限公司 | 用于检测il-33的测定 |
| TW202423972A (zh) | 2022-08-26 | 2024-06-16 | 英商梅迪繆思有限公司 | 使用抗介白素－３３抗體的氣喘治療 |
| US20240350682A1 (en) | 2023-04-12 | 2024-10-24 | Fusion Pharmaceuticals Inc. | Steap2-targeted compounds and use thereof |
| AU2024392535A1 (en) * | 2023-11-27 | 2026-06-04 | Glaxosmithkline Intellectual Property Development Limited | Il-33 binding antibodies |
| CN122341639A (zh) | 2023-12-07 | 2026-07-03 | 免疫医疗有限公司 | 治疗哮喘的方法 |
| TW202540173A (zh) | 2024-04-04 | 2025-10-16 | 英商梅迪繆思有限公司 | 治療及選擇對象之方法 |
| WO2025242619A1 (en) | 2024-05-20 | 2025-11-27 | Medimmune Limited | Treatment for mucus plugging |
| WO2025242618A1 (en) | 2024-05-20 | 2025-11-27 | Medimmune Limited | Bronchiectasis treatment |
| WO2025252012A1 (en) * | 2024-06-03 | 2025-12-11 | Fbd Biologics Limited | Engineered il-7 variants and methods of use thereof |
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| US4714681A (en) | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| GB2183662B (en) | 1985-04-01 | 1989-01-25 | Celltech Ltd | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| WO1989012624A2 (en) | 1988-06-14 | 1989-12-28 | Cetus Corporation | Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom |
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| HUE052220T2 (hu) | 2006-09-08 | 2021-04-28 | Abbvie Bahamas Ltd | Interleukin-13 kötõfehérjék |
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| CN105859889B (zh) * | 2010-11-17 | 2020-01-07 | 中外制药株式会社 | 具有代替凝血因子viii的功能的功能的多特异性抗原结合分子 |
| US8790651B2 (en) * | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
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| JO3532B1 (ar) * | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
| SG11201605580RA (en) * | 2014-01-10 | 2016-10-28 | Anaptysbio Inc | Antibodies directed against interleukin-33 (il-33) |
-
2016
- 2016-03-30 MX MX2017012616A patent/MX387295B/es unknown
- 2016-03-30 RU RU2017134909A patent/RU2736299C2/ru active
- 2016-03-30 SM SM20210086T patent/SMT202100086T1/it unknown
- 2016-03-30 SG SG11201707593UA patent/SG11201707593UA/en unknown
- 2016-03-30 NZ NZ736026A patent/NZ736026A/en unknown
- 2016-03-30 AU AU2016239331A patent/AU2016239331C1/en active Active
- 2016-03-30 CA CA2982400A patent/CA2982400C/en active Active
- 2016-03-30 HR HRP20210096TT patent/HRP20210096T1/hr unknown
- 2016-03-30 US US15/562,228 patent/US10668150B2/en active Active
- 2016-03-30 WO PCT/EP2016/056973 patent/WO2016156440A1/en not_active Ceased
- 2016-03-30 PL PL16712353T patent/PL3277717T3/pl unknown
- 2016-03-30 PT PT167123538T patent/PT3277717T/pt unknown
- 2016-03-30 KR KR1020177030936A patent/KR102261618B1/ko active Active
- 2016-03-30 EP EP20169253.0A patent/EP3733701A1/en not_active Ceased
- 2016-03-30 JP JP2017551294A patent/JP6862351B2/ja active Active
- 2016-03-30 SI SI201631069T patent/SI3277717T1/sl unknown
- 2016-03-30 LT LTEP16712353.8T patent/LT3277717T/lt unknown
- 2016-03-30 RS RS20210171A patent/RS61438B1/sr unknown
- 2016-03-30 EP EP16712353.8A patent/EP3277717B1/en active Active
- 2016-03-30 DK DK16712353.8T patent/DK3277717T3/da active
- 2016-03-30 HU HUE16712353A patent/HUE053097T2/hu unknown
- 2016-03-30 CN CN201680019480.3A patent/CN108064236B/zh active Active
- 2016-03-30 EP EP23219513.1A patent/EP4374916A3/en active Pending
- 2016-03-30 MY MYPI2017703606A patent/MY190209A/en unknown
- 2016-03-30 ES ES16712353T patent/ES2886114T3/es active Active
- 2016-03-31 TW TW105110432A patent/TWI721973B/zh active
-
2017
- 2017-09-18 IL IL254551A patent/IL254551A0/en unknown
- 2017-09-27 CL CL2017002433A patent/CL2017002433A1/es unknown
- 2017-10-23 CO CONC2017/0010753A patent/CO2017010753A2/es unknown
- 2017-10-30 ZA ZA2017/07355A patent/ZA201707355B/en unknown
-
2019
- 2019-10-17 AU AU2019250213A patent/AU2019250213B2/en active Active
-
2020
- 2020-04-10 US US16/845,121 patent/US11738081B2/en active Active
- 2020-09-02 CL CL2020002269A patent/CL2020002269A1/es unknown
- 2020-10-23 JP JP2020178437A patent/JP2021038226A/ja active Pending
-
2021
- 2021-01-10 IL IL280045A patent/IL280045B/en unknown
- 2021-02-17 CY CY20211100134T patent/CY1123925T1/el unknown
- 2021-10-25 AU AU2021257881A patent/AU2021257881B2/en active Active
-
2023
- 2023-07-05 US US18/346,884 patent/US20240016929A1/en active Pending
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