JP2018507861A5 - - Google Patents
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- JP2018507861A5 JP2018507861A5 JP2017544878A JP2017544878A JP2018507861A5 JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5 JP 2017544878 A JP2017544878 A JP 2017544878A JP 2017544878 A JP2017544878 A JP 2017544878A JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5
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- Prior art keywords
- optionally substituted
- pharmaceutically acceptable
- acceptable salt
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- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 C*C1CCNCC1 Chemical compound C*C1CCNCC1 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120671P | 2015-02-25 | 2015-02-25 | |
| US62/120,671 | 2015-02-25 | ||
| US201562200483P | 2015-08-03 | 2015-08-03 | |
| US62/200,483 | 2015-08-03 | ||
| PCT/US2016/019393 WO2016138158A1 (en) | 2015-02-25 | 2016-02-24 | Antiviral compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507861A JP2018507861A (ja) | 2018-03-22 |
| JP2018507861A5 true JP2018507861A5 (enExample) | 2019-04-25 |
| JP6716587B2 JP6716587B2 (ja) | 2020-07-01 |
Family
ID=56689780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017544878A Expired - Fee Related JP6716587B2 (ja) | 2015-02-25 | 2016-02-24 | 抗ウイルス化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358453B2 (enExample) |
| EP (1) | EP3262048A4 (enExample) |
| JP (1) | JP6716587B2 (enExample) |
| KR (2) | KR20210028752A (enExample) |
| CN (1) | CN107922427B (enExample) |
| AU (1) | AU2016222729B2 (enExample) |
| BR (1) | BR112017018022A2 (enExample) |
| CA (1) | CA2977150A1 (enExample) |
| EA (1) | EA038732B1 (enExample) |
| IL (1) | IL254011B (enExample) |
| MA (1) | MA41614A (enExample) |
| MX (1) | MX385571B (enExample) |
| PH (1) | PH12017501534A1 (enExample) |
| TW (1) | TWI704135B (enExample) |
| UA (1) | UA123393C2 (enExample) |
| WO (1) | WO2016138158A1 (enExample) |
Families Citing this family (35)
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| KR20150046259A (ko) | 2012-08-23 | 2015-04-29 | 앨리오스 바이오파마 인크. | 파라믹소바이러스 바이러스성 감염의 치료용 화합물 |
| US9243022B2 (en) | 2012-12-21 | 2016-01-26 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| CA2921294C (en) | 2013-08-21 | 2023-05-16 | Alios Biopharma, Inc. | Antiviral compounds |
| MY197231A (en) | 2015-07-22 | 2023-06-06 | Enanta Pharm Inc | Benzodiazepine derivatives as rsv inhibitors |
| US11554118B2 (en) * | 2017-03-22 | 2023-01-17 | Xibin Liao | Bruton's tyrosine kinase inhibitors |
| WO2018222774A1 (en) * | 2017-05-30 | 2018-12-06 | Alios Biopharma, Inc. | Methods for treating pneumoviruses |
| WO2019006295A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| CN111386118B (zh) | 2017-09-29 | 2023-05-09 | 英安塔制药有限公司 | 作为rsv抑制剂的组合药物剂 |
| WO2020048827A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
| CN109280027A (zh) * | 2018-12-13 | 2019-01-29 | 康化（上海）新药研发有限公司 | 一种5,6-二甲氧基-2-吡啶甲酸的合成方法 |
| WO2020190935A1 (en) | 2019-03-18 | 2020-09-24 | Enanta Pharmaceuticals, Inc. | Benzodiazepine derivatives as rsv inhibitors |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| PH12022550783A1 (en) * | 2019-10-04 | 2023-07-31 | Enanta Pharm Inc | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| MX2022010059A (es) | 2020-02-18 | 2022-08-25 | Bayer Ag | Nuevos compuestos de heteroaril-triazol como pesticidas. |
| WO2021198981A1 (en) | 2020-04-01 | 2021-10-07 | Janssen Biopharma, Inc. | Antiviral compounds and uses thereof |
| AU2021260799A1 (en) * | 2020-04-21 | 2023-01-05 | Janssen Sciences Ireland Unlimited Company | RSV inhibiting 3-substituted quinoline and cinnoline derivatives |
| WO2022010882A1 (en) | 2020-07-07 | 2022-01-13 | Enanta Pharmaceuticals, Inc, | Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors |
| WO2022086840A1 (en) | 2020-10-19 | 2022-04-28 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| TWI839652B (zh) | 2020-10-28 | 2024-04-21 | 日商鹽野義製藥股份有限公司 | 具有抗病毒活性的醯胺衍生物 |
| US12612412B2 (en) | 2021-02-26 | 2026-04-28 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| MX2023009961A (es) | 2021-02-26 | 2023-09-05 | Enanta Pharm Inc | Compuestos heterociclicos antivirales. |
| WO2022211812A1 (en) * | 2021-04-01 | 2022-10-06 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| WO2023052593A1 (en) | 2021-10-01 | 2023-04-06 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting spiro bearing derivatives |
| AR129003A1 (es) * | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| WO2023211997A1 (en) | 2022-04-27 | 2023-11-02 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2023237730A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo and spiro bearing derivatives |
| WO2023237732A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo bearing derivatives |
| CN115785080B (zh) * | 2022-12-16 | 2024-10-11 | 陕西盘龙药业集团股份有限公司 | 一种尿嘧啶母核类化合物及其制备方法和应用 |
| US20240383891A1 (en) * | 2023-05-16 | 2024-11-21 | Springworks Therapeutics, Inc. | Benzimidazole and related analogs for inhibiting yap/taz-tead |
| US20250066323A1 (en) * | 2023-08-17 | 2025-02-27 | Merck Sharp & Dohme Llc | Inhibitors of human respiratory syncytial virus and metapneumovirus |
| US11964954B1 (en) | 2023-08-29 | 2024-04-23 | King Faisal University | N'-[(2-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound |
| US11912697B1 (en) | 2023-08-29 | 2024-02-27 | King Faisal University | 1,3-benzothiazol-2-yl-N′-[(pyridine-3-carbonyl)oxy]ethanimidamide as an antitumor and antimicrobial compound |
| CN119161297A (zh) * | 2024-09-18 | 2024-12-20 | 浙江工业大学 | 一种4-溴-6-氯烟酸甲酯的制备方法 |
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| MA26487A1 (fr) | 1997-04-29 | 2004-12-20 | Smithkline Beecham Corp | Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . |
| BR9910621A (pt) | 1998-05-22 | 2001-01-30 | Smithkline Beecham Corp | Novos compostos de imidazol 2-alquil substituìdos |
| AR018915A1 (es) | 1998-06-24 | 2001-12-12 | Smithkline Beecham Corp | Inhibidores de proteasas diacilhidrazinicos, composicion farmaceutica que la comprenden, usos de los mismos para la manufactura de un medicamento, unprocedimiento de fabricacion de dichos compuestos |
| US6623741B1 (en) | 2000-02-29 | 2003-09-23 | Trimeris, Inc. | Methods and compositions for inhibition of membrane fusion-associated events including RSV transmission |
| US6878743B2 (en) | 2001-09-18 | 2005-04-12 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
| DE60234264D1 (de) | 2001-10-01 | 2009-12-17 | Bristol Myers Squibb Co | Spiro-hydantoin-verbindungen, die sich als entzündungshemmende mittel eignen |
| US20040071757A1 (en) * | 2001-11-20 | 2004-04-15 | David Rolf | Inhalation antiviral patch |
| WO2003048101A1 (en) | 2001-11-30 | 2003-06-12 | The Burnham Institute | Induction of apoptosis in cancer cells |
| BR0314595A (pt) | 2002-09-20 | 2005-08-09 | Arrow Therapeutics Ltd | Uso de um derivado de benzodiazepina ou um sal farmaceuticamente aceitável deste, inalador ou nebulisador, produto, usos de um produto e de um composto ou sal farmaceuticamente aceitável deste, derivado de benzodiazepina, composto, e, composição farmacêutica |
| JP4449389B2 (ja) | 2003-09-26 | 2010-04-14 | パナソニック株式会社 | プラズマディスプレイ装置用蛍光体の製造方法 |
| DE10348023A1 (de) | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
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| ATE435222T1 (de) | 2003-12-18 | 2009-07-15 | Tibotec Pharm Ltd | Aminobenzimidazole und benzimidazole als inhibitoren der replikation von respiratory syncytial virus |
| TWI349007B (en) * | 2003-12-18 | 2011-09-21 | Tibotec Pharm Ltd | Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication |
| AU2005211349A1 (en) | 2004-01-30 | 2005-08-18 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | N-benzyl-3,4-dihyroxypyridine-2-carboxamide and N-benzyl-2,3-dihydroxypyridine-4-carboxamide compounds useful as HIV integrase inhibitors |
| GB0406280D0 (en) | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Chemical compounds |
| DE102005024245A1 (de) * | 2005-05-27 | 2006-11-30 | Merck Patent Gmbh | Thienopyridine |
| AU2006260969B2 (en) | 2005-06-20 | 2011-11-17 | Janssen Sciences Ireland Uc | 1- ( 2-amino-3- (substituted alkyl)-3H-benzimidazolylmethyl) -3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus |
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| US20110105436A1 (en) | 2008-03-10 | 2011-05-05 | Auckland Uniservices Limited | Heteroaryl compounds, compositions, and methods of use in cancer treatment |
| US9173706B2 (en) | 2008-08-25 | 2015-11-03 | Covidien Lp | Dual-band dipole microwave ablation antenna |
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| US20100184815A1 (en) | 2008-12-19 | 2010-07-22 | Luehr Gary W | Agonists of peroxisome proliferator activated receptor-alpha |
| US20100278835A1 (en) | 2009-03-10 | 2010-11-04 | Astrazeneca Uk Limited | Novel compounds 660 |
| US20110033393A1 (en) | 2009-05-12 | 2011-02-10 | Stein Philip | Hydrazone Compounds and Their Use |
| US8791299B2 (en) | 2009-05-20 | 2014-07-29 | Universite Laval | Compounds for the inhibition of herpes viruses |
| HUE052510T2 (hu) * | 2009-05-27 | 2021-05-28 | Ptc Therapeutics Inc | Módszerek a rák és a nem daganatos állapotok kezelésére |
| CN102459332B (zh) | 2009-06-05 | 2015-08-19 | 埃博灵克斯股份有限公司 | 用于预防和/或治疗呼吸道感染的单价、二价和三价抗人呼吸道合胞病毒(hrsv)纳米抗体构建体 |
| RU2012102094A (ru) | 2009-06-26 | 2013-08-10 | Панацеа Биотек Лтд. | Новые азабициклогексаны |
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| GB201010193D0 (en) * | 2010-06-17 | 2010-07-21 | Respivert Ltd | Medicinal use |
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| JP2014530225A (ja) | 2011-10-11 | 2014-11-17 | エフ．ホフマン−ラ ロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 呼吸器合胞体ウイルス疾患の処置および予防のための化合物 |
| US8961959B2 (en) | 2011-10-17 | 2015-02-24 | The Regents Of The University Of Michigan | Glucosylceramide synthase inhibitors and therapeutic methods using the same |
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| EA027855B1 (ru) | 2012-04-17 | 2017-09-29 | Гайлид Сайэнсиз, Инк. | Соединения и способы для противовирусной терапии |
| WO2013186334A1 (en) | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| CA2873920C (en) | 2012-06-15 | 2021-07-20 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| JP2015519385A (ja) | 2012-06-15 | 2015-07-09 | ヤンセン・アールアンドデイ・アイルランド | Ｒｓウイルス抗ウイルス薬としての、ベンゾイミダゾールによって置換された新規４−置換１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体 |
| JP2015519387A (ja) | 2012-06-15 | 2015-07-09 | ヤンセン・アールアンドデイ・アイルランド | Ｒｓウイルス抗ウイルス薬としての、複素環によって置換された新規４−置換１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体 |
| BR112015000392A2 (pt) | 2012-07-10 | 2017-06-27 | Hoffmann La Roche | novos indazóis para o tratamento e profilaxia da infecção por vírus sincicial respiratório |
| KR20150046259A (ko) | 2012-08-23 | 2015-04-29 | 앨리오스 바이오파마 인크. | 파라믹소바이러스 바이러스성 감염의 치료용 화합물 |
| CA2921294C (en) | 2013-08-21 | 2023-05-16 | Alios Biopharma, Inc. | Antiviral compounds |
| EP3290407B1 (en) | 2013-10-18 | 2020-01-01 | Celgene Quanticel Research, Inc | Bromodomain inhibitors |
-
2016
- 2016-02-23 MA MA041614A patent/MA41614A/fr unknown
- 2016-02-24 CA CA2977150A patent/CA2977150A1/en active Pending
- 2016-02-24 JP JP2017544878A patent/JP6716587B2/ja not_active Expired - Fee Related
- 2016-02-24 CN CN201680024046.4A patent/CN107922427B/zh not_active Expired - Fee Related
- 2016-02-24 BR BR112017018022-7A patent/BR112017018022A2/pt not_active IP Right Cessation
- 2016-02-24 MX MX2017010933A patent/MX385571B/es unknown
- 2016-02-24 UA UAA201709269A patent/UA123393C2/uk unknown
- 2016-02-24 KR KR1020217006854A patent/KR20210028752A/ko not_active Ceased
- 2016-02-24 EP EP16756295.8A patent/EP3262048A4/en not_active Withdrawn
- 2016-02-24 US US15/052,631 patent/US10358453B2/en active Active
- 2016-02-24 AU AU2016222729A patent/AU2016222729B2/en not_active Ceased
- 2016-02-24 WO PCT/US2016/019393 patent/WO2016138158A1/en not_active Ceased
- 2016-02-24 KR KR1020177026450A patent/KR20170122775A/ko not_active Withdrawn
- 2016-02-24 EA EA201791886A patent/EA038732B1/ru unknown
- 2016-02-25 TW TW105105765A patent/TWI704135B/zh not_active IP Right Cessation
-
2017
- 2017-08-15 IL IL254011A patent/IL254011B/en unknown
- 2017-08-24 PH PH12017501534A patent/PH12017501534A1/en unknown
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