JP2018507861A5 - - Google Patents
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- JP2018507861A5 JP2018507861A5 JP2017544878A JP2017544878A JP2018507861A5 JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5 JP 2017544878 A JP2017544878 A JP 2017544878A JP 2017544878 A JP2017544878 A JP 2017544878A JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- pharmaceutically acceptable
- acceptable salt
- compound according
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 C*C1CCNCC1 Chemical compound C*C1CCNCC1 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120671P | 2015-02-25 | 2015-02-25 | |
| US62/120,671 | 2015-02-25 | ||
| US201562200483P | 2015-08-03 | 2015-08-03 | |
| US62/200,483 | 2015-08-03 | ||
| PCT/US2016/019393 WO2016138158A1 (en) | 2015-02-25 | 2016-02-24 | Antiviral compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507861A JP2018507861A (ja) | 2018-03-22 |
| JP2018507861A5 true JP2018507861A5 (enExample) | 2019-04-25 |
| JP6716587B2 JP6716587B2 (ja) | 2020-07-01 |
Family
ID=56689780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017544878A Expired - Fee Related JP6716587B2 (ja) | 2015-02-25 | 2016-02-24 | 抗ウイルス化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358453B2 (enExample) |
| EP (1) | EP3262048A4 (enExample) |
| JP (1) | JP6716587B2 (enExample) |
| KR (2) | KR20170122775A (enExample) |
| CN (1) | CN107922427B (enExample) |
| AU (1) | AU2016222729B2 (enExample) |
| BR (1) | BR112017018022A2 (enExample) |
| CA (1) | CA2977150A1 (enExample) |
| EA (1) | EA038732B1 (enExample) |
| IL (1) | IL254011B (enExample) |
| MA (1) | MA41614A (enExample) |
| MX (1) | MX385571B (enExample) |
| PH (1) | PH12017501534A1 (enExample) |
| TW (1) | TWI704135B (enExample) |
| UA (1) | UA123393C2 (enExample) |
| WO (1) | WO2016138158A1 (enExample) |
Families Citing this family (34)
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| US9724351B2 (en) | 2012-08-23 | 2017-08-08 | Alios Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| GEP201706757B (en) | 2012-12-21 | 2017-10-25 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| PH12021550330A1 (en) | 2013-08-21 | 2022-09-28 | Janssen Biopharma Inc | Antiviral compounds |
| MY197231A (en) | 2015-07-22 | 2023-06-06 | Enanta Pharm Inc | Benzodiazepine derivatives as rsv inhibitors |
| US11554118B2 (en) * | 2017-03-22 | 2023-01-17 | Xibin Liao | Bruton's tyrosine kinase inhibitors |
| WO2018222774A1 (en) * | 2017-05-30 | 2018-12-06 | Alios Biopharma, Inc. | Methods for treating pneumoviruses |
| WO2019006295A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| WO2019067864A1 (en) | 2017-09-29 | 2019-04-04 | Enanta Pharmaceuticals, Inc. | PHARMACEUTICAL AGENTS IN COMBINATION AS INHIBITORS OF RSV |
| WO2020048827A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
| CN109280027A (zh) * | 2018-12-13 | 2019-01-29 | 康化（上海）新药研发有限公司 | 一种5,6-二甲氧基-2-吡啶甲酸的合成方法 |
| CA3133300A1 (en) | 2019-03-18 | 2020-09-24 | Enanta Pharmaceuticals, Inc. | Benzodiazepine derivatives as rsv inhibitors |
| IL291834B1 (en) * | 2019-10-04 | 2026-02-01 | Enanta Pharm Inc | Antiviral heterocyclic compounds |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| US20230148601A1 (en) | 2020-02-18 | 2023-05-18 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
| WO2021198981A1 (en) | 2020-04-01 | 2021-10-07 | Janssen Biopharma, Inc. | Antiviral compounds and uses thereof |
| AU2021260799A1 (en) * | 2020-04-21 | 2023-01-05 | Janssen Sciences Ireland Unlimited Company | RSV inhibiting 3-substituted quinoline and cinnoline derivatives |
| US11534439B2 (en) | 2020-07-07 | 2022-12-27 | Enanta Pharmaceuticals, Inc. | Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors |
| WO2022086840A1 (en) | 2020-10-19 | 2022-04-28 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| CN121021491A (zh) | 2020-10-28 | 2025-11-28 | 盐野义制药株式会社 | 具有抗病毒活性的酰胺衍生物 |
| IL305189A (en) | 2021-02-26 | 2023-10-01 | Enanta Pharm Inc | Heterocyclic antiviral compounds |
| US12612412B2 (en) | 2021-02-26 | 2026-04-28 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| WO2022211812A1 (en) * | 2021-04-01 | 2022-10-06 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| WO2023052593A1 (en) | 2021-10-01 | 2023-04-06 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting spiro bearing derivatives |
| AR129003A1 (es) | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| WO2023211997A1 (en) | 2022-04-27 | 2023-11-02 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2023237730A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo and spiro bearing derivatives |
| WO2023237732A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo bearing derivatives |
| CN115785080B (zh) * | 2022-12-16 | 2024-10-11 | 陕西盘龙药业集团股份有限公司 | 一种尿嘧啶母核类化合物及其制备方法和应用 |
| WO2025038786A1 (en) * | 2023-08-17 | 2025-02-20 | Merck Sharp & Dohme Llc | Inhibitors of human respiratory syncytial virus and metapneumovirus |
| US11964954B1 (en) | 2023-08-29 | 2024-04-23 | King Faisal University | N'-[(2-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound |
| US11912697B1 (en) | 2023-08-29 | 2024-02-27 | King Faisal University | 1,3-benzothiazol-2-yl-N′-[(pyridine-3-carbonyl)oxy]ethanimidamide as an antitumor and antimicrobial compound |
| CN119161297A (zh) * | 2024-09-18 | 2024-12-20 | 浙江工业大学 | 一种4-溴-6-氯烟酸甲酯的制备方法 |
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| MA26487A1 (fr) | 1997-04-29 | 2004-12-20 | Smithkline Beecham Corp | Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . |
| NZ526958A (en) | 1998-05-22 | 2004-12-24 | Smithkline Beecham Corp | Novel 2-alkyl substituted imidazole compounds |
| AR018915A1 (es) | 1998-06-24 | 2001-12-12 | Smithkline Beecham Corp | Inhibidores de proteasas diacilhidrazinicos, composicion farmaceutica que la comprenden, usos de los mismos para la manufactura de un medicamento, unprocedimiento de fabricacion de dichos compuestos |
| US6623741B1 (en) | 2000-02-29 | 2003-09-23 | Trimeris, Inc. | Methods and compositions for inhibition of membrane fusion-associated events including RSV transmission |
| US6878743B2 (en) | 2001-09-18 | 2005-04-12 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
| IL160990A0 (en) | 2001-10-01 | 2004-08-31 | Bristol Myers Squibb Co | Spiro-hydantoin compounds useful as anti-inflammatory agents |
| US20040071757A1 (en) * | 2001-11-20 | 2004-04-15 | David Rolf | Inhalation antiviral patch |
| CN100348569C (zh) | 2001-11-30 | 2007-11-14 | 伯哈姆学院 | 癌细胞中编程性细胞死亡的诱导 |
| AU2003267587B2 (en) * | 2002-09-20 | 2010-05-20 | Arrow Therapeutics Limited | Benzodiazepine derivatives and pharmaceutical compositions containing them |
| JP4449389B2 (ja) | 2003-09-26 | 2010-04-14 | パナソニック株式会社 | プラズマディスプレイ装置用蛍光体の製造方法 |
| DE10348023A1 (de) | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| US7323567B2 (en) | 2003-10-30 | 2008-01-29 | Boehringer Ingelheim (Canada) Ltd. | RSV polymerase inhibitors |
| CN1906192A (zh) * | 2003-11-14 | 2007-01-31 | 3M创新有限公司 | 羟胺取代的咪唑环化合物 |
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| CN103450159A (zh) * | 2003-12-18 | 2013-12-18 | 泰博特克药品有限公司 | 作为呼吸道合胞病毒复制的抑制剂的哌啶-氨基-苯并咪唑类衍生物 |
| CA2554120A1 (en) | 2004-01-30 | 2005-08-18 | Merck & Co., Inc. | N-benzyl-3,4-dihydroxypyridine-2-carboxamide and n-benzyl-2,3-dihydroxypyridine-4-carboxamide compounds useful as hiv integras inhibitors |
| GB0406280D0 (en) | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Chemical compounds |
| DE102005024245A1 (de) * | 2005-05-27 | 2006-11-30 | Merck Patent Gmbh | Thienopyridine |
| MX2007016537A (es) | 2005-06-20 | 2008-03-06 | Tibotec Pharm Ltd | 1,3-dihidro-benzoimidazol-onas 1-(2-amino-3-(alquilo sustituido)-3h-bencimidazolilmetil)-3-sustituidas con actividad sobre virus respiratorios sinciciales. |
| US7572810B2 (en) | 2006-06-08 | 2009-08-11 | Bristol-Myers Squibb Company | Alkene piperidine derivatives as antiviral agents |
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| WO2009114552A1 (en) | 2008-03-10 | 2009-09-17 | The Board Of Trustees Of The Leland Stanford Junior University | Heteroaryl compounds, compositions, and methods of use in cancer treatment |
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| HUE052510T2 (hu) * | 2009-05-27 | 2021-05-28 | Ptc Therapeutics Inc | Módszerek a rák és a nem daganatos állapotok kezelésére |
| KR101852204B1 (ko) | 2009-06-05 | 2018-04-26 | 아블린쓰 엔.브이. | 기도 감염의 예방 및/또는 치료를 위한 일가, 이가 및 삼가 항 인간 호흡기 세포융합 바이러스 (ｈｒｓｖ) 나노바디 구조물 |
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| WO2011097607A1 (en) | 2010-02-08 | 2011-08-11 | Southern Research Institute | Anti-viral treatment and assay to screen for anti-viral agent |
| GB201010193D0 (en) * | 2010-06-17 | 2010-07-21 | Respivert Ltd | Medicinal use |
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| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
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| EP2548877A1 (en) | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| JP5890522B2 (ja) * | 2011-08-05 | 2016-03-22 | ビオタ サイエンティフィック マネージメント ピーティーワイ リミテッド | 呼吸器合胞体ウイルス感染症処置用化合物 |
| AU2012311698B2 (en) | 2011-09-22 | 2017-06-22 | Merck Sharp & Dohme B.V. | N-piperidin-4-yl derivatives |
| CA2847071A1 (en) | 2011-10-11 | 2013-04-18 | F. Hoffmann-La Roche Ag | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease |
| WO2013059119A1 (en) | 2011-10-17 | 2013-04-25 | The Regents Of The University Of Michigan | Glucosylceramide synthase inhibitors and therapeutic methods using the same |
| BR112014010566A2 (pt) | 2011-11-04 | 2017-04-25 | Syngenta Participations Ag | compostos pesticidas |
| WO2013081400A2 (ko) | 2011-11-29 | 2013-06-06 | 주식회사 비보존 | 신규한 벤즈아마이드 유도체 및 그 용도 |
| JP6122868B2 (ja) | 2011-12-22 | 2017-04-26 | ギリアード サイエンシーズ， インコーポレイテッド | 抗ウイルス剤としてのピラゾロ［１，５−ａ］ピリミジン |
| KR102181318B1 (ko) | 2012-04-17 | 2020-11-20 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 치료를 위한 화합물 및 방법 |
| PL2864323T3 (pl) | 2012-06-15 | 2017-09-29 | Janssen Sciences Ireland Uc | Pochodne 1,3-dihydro-2h-benzoimidazol-2-onu podstawione heterocyklami jako środki przeciwwirusowe przeciwko wirusowi syncytium nabłonka oddechowego |
| CA2873925A1 (en) | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| EP2864299A1 (en) | 2012-06-15 | 2015-04-29 | Janssen Sciences Ireland UC | 4 - substituted 1, 3 - dihydro - 2h - benzimidazol - 2 - one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| CA2873921A1 (en) | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| JP2015522052A (ja) | 2012-07-10 | 2015-08-03 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 呼吸器合胞体ウイルス感染症の治療及び予防のための新規インダゾール |
| US9724351B2 (en) * | 2012-08-23 | 2017-08-08 | Alios Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| PH12021550330A1 (en) * | 2013-08-21 | 2022-09-28 | Janssen Biopharma Inc | Antiviral compounds |
| DK3290407T3 (da) | 2013-10-18 | 2020-03-23 | Celgene Quanticel Res Inc | Bromodomæneinhibitorer |
-
2016
- 2016-02-23 MA MA041614A patent/MA41614A/fr unknown
- 2016-02-24 WO PCT/US2016/019393 patent/WO2016138158A1/en not_active Ceased
- 2016-02-24 MX MX2017010933A patent/MX385571B/es unknown
- 2016-02-24 JP JP2017544878A patent/JP6716587B2/ja not_active Expired - Fee Related
- 2016-02-24 CA CA2977150A patent/CA2977150A1/en active Pending
- 2016-02-24 BR BR112017018022-7A patent/BR112017018022A2/pt not_active IP Right Cessation
- 2016-02-24 CN CN201680024046.4A patent/CN107922427B/zh not_active Expired - Fee Related
- 2016-02-24 AU AU2016222729A patent/AU2016222729B2/en not_active Ceased
- 2016-02-24 US US15/052,631 patent/US10358453B2/en active Active
- 2016-02-24 EP EP16756295.8A patent/EP3262048A4/en not_active Withdrawn
- 2016-02-24 UA UAA201709269A patent/UA123393C2/uk unknown
- 2016-02-24 EA EA201791886A patent/EA038732B1/ru unknown
- 2016-02-24 KR KR1020177026450A patent/KR20170122775A/ko not_active Withdrawn
- 2016-02-24 KR KR1020217006854A patent/KR20210028752A/ko not_active Ceased
- 2016-02-25 TW TW105105765A patent/TWI704135B/zh not_active IP Right Cessation
-
2017
- 2017-08-15 IL IL254011A patent/IL254011B/en unknown
- 2017-08-24 PH PH12017501534A patent/PH12017501534A1/en unknown
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