JP2018500287A5 - - Google Patents
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- JP2018500287A5 JP2018500287A5 JP2017523358A JP2017523358A JP2018500287A5 JP 2018500287 A5 JP2018500287 A5 JP 2018500287A5 JP 2017523358 A JP2017523358 A JP 2017523358A JP 2017523358 A JP2017523358 A JP 2017523358A JP 2018500287 A5 JP2018500287 A5 JP 2018500287A5
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- JP
- Japan
- Prior art keywords
- disease
- disorder
- compound
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072563P | 2014-10-30 | 2014-10-30 | |
| US62/072,563 | 2014-10-30 | ||
| PCT/US2015/058193 WO2016069974A1 (en) | 2014-10-30 | 2015-10-30 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018200608A Division JP6623270B2 (ja) | 2014-10-30 | 2018-10-25 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
| JP2020104927A Division JP2020180129A (ja) | 2014-10-30 | 2020-06-18 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500287A JP2018500287A (ja) | 2018-01-11 |
| JP2018500287A5 true JP2018500287A5 (enExample) | 2018-12-06 |
| JP6998204B2 JP6998204B2 (ja) | 2022-02-04 |
Family
ID=54754732
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523358A Expired - Fee Related JP6998204B2 (ja) | 2014-10-30 | 2015-10-30 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
| JP2018200608A Expired - Fee Related JP6623270B2 (ja) | 2014-10-30 | 2018-10-25 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
| JP2020104927A Withdrawn JP2020180129A (ja) | 2014-10-30 | 2020-06-18 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018200608A Expired - Fee Related JP6623270B2 (ja) | 2014-10-30 | 2018-10-25 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
| JP2020104927A Withdrawn JP2020180129A (ja) | 2014-10-30 | 2020-06-18 | Ｒｏｒγｔのモジュレーターとしてのトリフルオロメチルアルコール |
Country Status (40)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201803869A (zh) * | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為ＲＯＲγＴ調節劑之６－胺基吡啶－３－基噻唑 |
| US11230555B2 (en) | 2018-03-12 | 2022-01-25 | Escalier Biosciences B.V. | Bicyclic RORγ modulators |
| EP3765020A4 (en) | 2018-03-12 | 2021-09-22 | Escalier Biosciences B.V. | SPIROCYCLIC MMR-GAMMA MODULATORS |
| JP2021529161A (ja) | 2018-06-18 | 2021-10-28 | ヤンセン ファーマシューティカ エヌ．ベー． | ＲＯＲγｔのモジュレーターとしてのピリジニルピラゾール |
| JP2021528405A (ja) | 2018-06-18 | 2021-10-21 | ヤンセン ファーマシューティカ エヌ．ベー． | ＲＯＲγｔのモジュレータとしてのアミド置換チアゾール |
| CA3103770A1 (en) * | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | Phenyl and pyridinyl substituted imidazoles as modulators of roryt |
| WO2019244001A1 (en) | 2018-06-18 | 2019-12-26 | Janssen Pharmaceutica Nv | 6-aminopyridin-3-yl pyrazoles as modulators of roryt |
| WO2023232870A1 (en) | 2022-05-31 | 2023-12-07 | Immunic Ag | Rorg/rorgt modulators for the treatment of virus infections like covid-19 |
| WO2024089216A1 (en) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Novel sulfur-containing heteroaryl carboxamide compounds |
| CN119528866B (zh) * | 2024-11-28 | 2025-10-17 | 河南农业大学 | 一种含双三氟甲基的香豆素叔醇类化合物及其制备方法和应用 |
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| EA007933B1 (ru) | 2001-08-13 | 2007-02-27 | Янссен Фармацевтика Н.В. | 2,4,5-тризамещенные производные тиазолила и их противовоспалительная активность |
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| US8188128B2 (en) | 2005-05-12 | 2012-05-29 | The University Of Medicine And Dentistry Of New Jersey | Opioid receptor subtype-selective agents |
| GB0518237D0 (en) * | 2005-09-07 | 2005-10-19 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| WO2007087427A2 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Thiazole and thiadiazole compounds for inflammation and immune-related uses |
| WO2008064318A2 (en) | 2006-11-22 | 2008-05-29 | University Of Medicine And Dentistry Of New Jersey | Peripheral opioid receptor active compounds |
| WO2008064317A1 (en) | 2006-11-22 | 2008-05-29 | University Of Medicine And Dentistry Of New Jersey | Lipophilic opioid receptor active compounds |
| WO2009011850A2 (en) | 2007-07-16 | 2009-01-22 | Abbott Laboratories | Novel therapeutic compounds |
| EP2586311B1 (de) | 2008-07-17 | 2016-12-14 | Bayer CropScience AG | Heterocyclische Verbindungen als Schädlingsbekämpfungsmittel |
| WO2010118078A1 (en) * | 2009-04-08 | 2010-10-14 | Idenix Pharmaceuticals, Inc. | Macrocyclic serine protease inhibitors |
| AR079022A1 (es) | 2009-11-02 | 2011-12-21 | Sanofi Aventis | Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion |
| EP2368886A1 (en) * | 2010-03-01 | 2011-09-28 | Phenex Pharmaceuticals AG | Novel compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (ROR gamma, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune desease |
| EP3002008B8 (en) | 2010-03-11 | 2018-10-24 | New York University | Amido compounds as roryt modulators and uses thereof |
| WO2011112264A1 (en) | 2010-03-11 | 2011-09-15 | New York University | Compounds as rorϒt modulators and uses thereof |
| WO2011115892A1 (en) | 2010-03-15 | 2011-09-22 | Griffin Patrick R | Modulators of the retinoic acid receptor-related orphan receptors |
| WO2012027965A1 (en) | 2010-09-01 | 2012-03-08 | Glaxo Group Limited | Novel compounds |
| WO2012074547A2 (en) | 2010-11-29 | 2012-06-07 | New York University | STEROID COMPOUNDS AS RORγt MODULATORS AND USES THEREOF |
| KR101958699B1 (ko) | 2010-12-28 | 2019-03-15 | 라이온 가부시키가이샤 | 구강 상태의 판정 방법, 그리고 그것을 위해 사용되는 분석 용구, 장치, 및 프로그램 |
| WO2012129491A1 (en) | 2011-03-24 | 2012-09-27 | Abbott Laboratories | Trpv3 modulators |
| US9586928B2 (en) | 2011-05-16 | 2017-03-07 | The Scripps Research Institute | Modulators of the nuclear hormone receptor ROR |
| EP2738170B1 (en) | 2011-07-29 | 2017-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| JP2014528933A (ja) | 2011-09-09 | 2014-10-30 | ニューヨーク ユニバーシティ | ＲＯＲγｔモジュレーターとしてのアミド化合物およびその使用 |
| GB201116641D0 (en) * | 2011-09-27 | 2011-11-09 | Glaxo Group Ltd | Novel compounds |
| US9815851B2 (en) | 2011-12-02 | 2017-11-14 | Phenex Pharmaceuticals Ag | Pyrrolo carboxamides as modulators of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases |
| US20130190356A1 (en) | 2011-12-22 | 2013-07-25 | Genentech, Inc. | Benzyl sulfonamide derivatives as rorc modulators |
| UY34832A (es) * | 2012-05-31 | 2013-12-31 | Phenex Pharmaceuticals Ag | TIAZOLES SUSTITUIDOS POR CARBOXAMIDA O SULFONAMIDA Y DERIVADOS RELACIONADOS COMO MODULADORES PARA EL RECEPTOR NUCLEAR HUÉRFANO RORy (lambda) |
| JO3215B1 (ar) | 2012-08-09 | 2018-03-08 | Phenex Pharmaceuticals Ag | حلقات غير متجانسة بها 5 ذرات تحتوي على النيتروجين بها استبدال بكربوكساميد أو سلفوناميد كمعدلات لمستقبل نووي غير محمي RORy |
| WO2014062667A1 (en) * | 2012-10-16 | 2014-04-24 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of ror-gamma-t |
| US9624210B2 (en) * | 2012-12-12 | 2017-04-18 | Merck Sharp & Dohme Corp. | Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors |
| WO2014195321A1 (en) | 2013-06-04 | 2014-12-11 | Acturum Life Science AB | Triazole compounds and their use as gamma secretase modulators |
| CN103333168B (zh) * | 2013-07-23 | 2015-08-05 | 清华大学 | 一种酰胺类化合物及其制备方法与应用 |
| US9663469B2 (en) | 2013-09-09 | 2017-05-30 | Bristol-Myers Squibb Company | RORγ modulators |
| US20150072890A1 (en) | 2013-09-11 | 2015-03-12 | 20/20 Gene Systems, Inc. | Methods and compositions for aiding in the detection of lung cancer |
| CN105555768B (zh) | 2013-09-20 | 2018-10-16 | 百时美施贵宝公司 | RORγ调节剂 |
| WO2015057629A1 (en) * | 2013-10-15 | 2015-04-23 | Janssen Pharmaceutica Nv | ALKYL LINKED QUINOLINYL MODULATORS OF RORyt |
| WO2015057206A1 (en) * | 2013-10-15 | 2015-04-23 | Janssen Pharmaceutica Nv | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt |
| US9738600B2 (en) | 2013-12-05 | 2017-08-22 | Lead Pharma Cel Models Ip B.V. | ROR gamma (RORγ) modulators |
| CN106132931B (zh) | 2014-01-06 | 2019-08-02 | 百时美施贵宝公司 | 碳环砜RORγ调节剂 |
| US9637455B2 (en) | 2014-01-06 | 2017-05-02 | Bristol-Myers Squibb Company | Heterocyclic sulfone RORγ modulators |
| ES2704460T3 (es) | 2014-01-06 | 2019-03-18 | Bristol Myers Squibb Co | Moduladores de ROR gamma de ciclohexilsulfona |
| JP6530764B2 (ja) | 2014-01-06 | 2019-06-12 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ＲＯＲγ調節因子としてのピロリジニルスルホン誘導体およびその使用 |
| US11084784B2 (en) | 2014-03-27 | 2021-08-10 | Piramal Enterprises Limited | ROR-gamma modulators and uses thereof |
| KR20170075787A (ko) | 2014-10-30 | 2017-07-03 | 얀센 파마슈티카 엔.브이. | RORγt의 조절제로서의 아미드 치환된 티아졸 |
| LT3212641T (lt) | 2014-10-30 | 2019-02-11 | Janssen Pharmaceutica Nv | Tiazolai, kaip roryt moduliatoriai |
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2014
- 2014-10-30 JO JOP/2020/0117A patent/JOP20200117A1/ar unknown
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2015
- 2015-10-28 TW TW104135342A patent/TWI667230B/zh not_active IP Right Cessation
- 2015-10-28 TW TW108110613A patent/TWI705057B/zh not_active IP Right Cessation
- 2015-10-29 JO JOP/2015/0267A patent/JO3571B1/ar active
- 2015-10-29 MA MA40873A patent/MA40873B1/fr unknown
- 2015-10-30 CA CA2965512A patent/CA2965512C/en active Active
- 2015-10-30 LT LTEP15802227.7T patent/LT3212643T/lt unknown
- 2015-10-30 EA EA201790942A patent/EA033699B1/ru not_active IP Right Cessation
- 2015-10-30 HU HUE15802227A patent/HUE043624T2/hu unknown
- 2015-10-30 WO PCT/US2015/058193 patent/WO2016069974A1/en not_active Ceased
- 2015-10-30 ES ES18160676T patent/ES2858503T3/es active Active
- 2015-10-30 PT PT15802227T patent/PT3212643T/pt unknown
- 2015-10-30 SI SI201530677T patent/SI3212643T1/sl unknown
- 2015-10-30 CN CN201711211144.1A patent/CN107827841A/zh active Pending
- 2015-10-30 DK DK15802227.7T patent/DK3212643T3/da active
- 2015-10-30 RS RS20190495A patent/RS58613B1/sr unknown
- 2015-10-30 AR ARP150103522A patent/AR102480A1/es unknown
- 2015-10-30 PE PE2017002473A patent/PE20180250A1/es unknown
- 2015-10-30 CN CN201580071983.0A patent/CN107108599A/zh active Pending
- 2015-10-30 JP JP2017523358A patent/JP6998204B2/ja not_active Expired - Fee Related
- 2015-10-30 CR CR20170542A patent/CR20170542A/es unknown
- 2015-10-30 SM SM20190290T patent/SMT201900290T1/it unknown
- 2015-10-30 KR KR1020177032857A patent/KR20170127580A/ko not_active Ceased
- 2015-10-30 EP EP18160676.5A patent/EP3354651B1/en active Active
- 2015-10-30 BR BR122017023050A patent/BR122017023050A2/pt not_active Application Discontinuation
- 2015-10-30 UY UY0001036377A patent/UY36377A/es unknown
- 2015-10-30 MX MX2018004348A patent/MX369567B/es unknown
- 2015-10-30 HR HRP20190900TT patent/HRP20190900T1/hr unknown
- 2015-10-30 ME MEP-2019-118A patent/ME03426B/me unknown
- 2015-10-30 ES ES15802227T patent/ES2724556T3/es active Active
- 2015-10-30 US US14/927,499 patent/US9850236B2/en not_active Expired - Fee Related
- 2015-10-30 EA EA201891562A patent/EA035998B1/ru not_active IP Right Cessation
- 2015-10-30 SG SG10201805355YA patent/SG10201805355YA/en unknown
- 2015-10-30 PL PL15802227T patent/PL3212643T3/pl unknown
- 2015-10-30 KR KR1020177014519A patent/KR20170078750A/ko not_active Ceased
- 2015-10-30 AU AU2015339087A patent/AU2015339087B2/en not_active Ceased
- 2015-10-30 CN CN202110007104.5A patent/CN112979630A/zh active Pending
- 2015-10-30 TR TR2019/07763T patent/TR201907763T4/tr unknown
- 2015-10-30 PE PE2017000795A patent/PE20171649A1/es unknown
- 2015-10-30 MX MX2017005689A patent/MX367912B/es active IP Right Grant
- 2015-10-30 EP EP15802227.7A patent/EP3212643B1/en active Active
- 2015-10-30 SG SG11201703323PA patent/SG11201703323PA/en unknown
- 2015-10-30 CR CR20170166A patent/CR20170166A/es unknown
- 2015-10-30 BR BR112017008816A patent/BR112017008816A2/pt not_active Application Discontinuation
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2017
- 2017-04-23 IL IL251865A patent/IL251865A0/en unknown
- 2017-04-27 CL CL2017001042A patent/CL2017001042A1/es unknown
- 2017-04-27 PH PH12017500800A patent/PH12017500800A1/en unknown
- 2017-04-28 SV SV2017005429A patent/SV2017005429A/es unknown
- 2017-04-28 GT GT201700090A patent/GT201700090A/es unknown
- 2017-05-19 CO CONC2017/0005014A patent/CO2017005014A2/es unknown
- 2017-05-29 ZA ZA2017/03679A patent/ZA201703679B/en unknown
- 2017-05-30 EC ECIEPI201733054A patent/ECSP17033054A/es unknown
- 2017-07-31 US US15/664,673 patent/US10150762B2/en active Active
- 2017-11-08 AR ARP170103107A patent/AR110155A2/es unknown
- 2017-11-14 IL IL255648A patent/IL255648B/en active IP Right Grant
- 2017-11-20 PH PH12017502105A patent/PH12017502105A1/en unknown
- 2017-12-14 UY UY0001037517A patent/UY37517A/es unknown
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2018
- 2018-02-16 CL CL2018000436A patent/CL2018000436A1/es unknown
- 2018-08-31 ZA ZA201805860A patent/ZA201805860B/en unknown
- 2018-08-31 ZA ZA201805861A patent/ZA201805861B/en unknown
- 2018-10-25 JP JP2018200608A patent/JP6623270B2/ja not_active Expired - Fee Related
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2019
- 2019-01-14 AU AU2019200228A patent/AU2019200228B2/en not_active Ceased
- 2019-06-04 CL CL2019001514A patent/CL2019001514A1/es unknown
- 2019-06-14 CY CY20191100620T patent/CY1121716T1/el unknown
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2020
- 2020-06-18 JP JP2020104927A patent/JP2020180129A/ja not_active Withdrawn