JO3571B1 - كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ror-gamma-t - Google Patents

كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ror-gamma-t

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Publication number
JO3571B1
JO3571B1 JOP/2015/0267A JOP20150267A JO3571B1 JO 3571 B1 JO3571 B1 JO 3571B1 JO P20150267 A JOP20150267 A JO P20150267A JO 3571 B1 JO3571 B1 JO 3571B1
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Jordan
Prior art keywords
ror
gamma
modulators
syndrome
disorder
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JOP/2015/0267A
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English (en)
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Goldberg Steven
Tanis Virginia
Gege Christian
Venkatesan Hariharan
Hoffmann Thomas
Kinzel Olaf
Steeneck Christoph
Kleymann Gerald
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Janssen Pharmaceutica Nv
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Abstract

يشتمل هذا الاختراع على مركبات بالصيغة<span dir="LTR">I</span>. الصيغة<span dir="LTR">I</span> <pre> <span dir="RTL"> حيث يشتمل الوصف على تعريف كل من</span>X<span dir="RTL">و </span>A1<span dir="RTL">و </span>A2<span dir="RTL">و </span>A3<span dir="RTL">و </span>A4<span dir="RTL">و </span>R1<span dir="RTL">و </span>R2<span dir="RTL">و </span>R3<span dir="RTL"> يتضمن هذا الاختراع أيضًا طريقة لمعالجة أو تحسين متلازمة أو اضطراب أو مرض،حيث تكون المتلازمة أو الاضطراب أوالمرض المذكور هو التهاب المفاصل الروماتويدي أوالصدفية. يتعلق الاختراع أيضا بطريقة لتعديل نشاط المستقبل</span><strong> ROR-GAMMA-T</strong> <span dir="RTL">لدى</span> <span dir="RTL">كائن ثدييّ وذلك بإعطائه كمية فعّالة علاجيًا من مركب واحد على الأقل بالصيغة لعنصرالحماية</span> 1</pre>
JOP/2015/0267A 2014-10-30 2015-10-29 كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ror-gamma-t JO3571B1 (ar)

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JOP/2015/0267A JO3571B1 (ar) 2014-10-30 2015-10-29 كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ror-gamma-t

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