JP2012502111A5 - - Google Patents

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Publication number
JP2012502111A5
JP2012502111A5 JP2011526999A JP2011526999A JP2012502111A5 JP 2012502111 A5 JP2012502111 A5 JP 2012502111A5 JP 2011526999 A JP2011526999 A JP 2011526999A JP 2011526999 A JP2011526999 A JP 2011526999A JP 2012502111 A5 JP2012502111 A5 JP 2012502111A5
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JP
Japan
Prior art keywords
compound
alkyl
occurrence
haloalkyl
halogen
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JP2011526999A
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English (en)
Japanese (ja)
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JP2012502111A (ja
JP5567573B2 (ja
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Priority claimed from PCT/US2009/056675 external-priority patent/WO2010030891A2/en
Publication of JP2012502111A publication Critical patent/JP2012502111A/ja
Publication of JP2012502111A5 publication Critical patent/JP2012502111A5/ja
Application granted granted Critical
Publication of JP5567573B2 publication Critical patent/JP5567573B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011526999A 2008-09-11 2009-09-11 アリールグアニジンf1f0−atpアーゼ阻害剤およびそれと関連する方法 Expired - Fee Related JP5567573B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9618408P 2008-09-11 2008-09-11
US61/096,184 2008-09-11
PCT/US2009/056675 WO2010030891A2 (en) 2008-09-11 2009-09-11 Aryl guanidine f1f0-atpase inhibitors and related methods

Publications (3)

Publication Number Publication Date
JP2012502111A JP2012502111A (ja) 2012-01-26
JP2012502111A5 true JP2012502111A5 (enExample) 2012-10-25
JP5567573B2 JP5567573B2 (ja) 2014-08-06

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ID=42005765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011526999A Expired - Fee Related JP5567573B2 (ja) 2008-09-11 2009-09-11 アリールグアニジンf1f0−atpアーゼ阻害剤およびそれと関連する方法

Country Status (5)

Country Link
US (1) US8497307B2 (enExample)
EP (1) EP2352724B1 (enExample)
JP (1) JP5567573B2 (enExample)
AU (1) AU2009291632B2 (enExample)
WO (1) WO2010030891A2 (enExample)

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CN103458886B (zh) 2010-12-08 2016-06-08 莱斯拉公司 吡啶酮基胍f1f0-atp酶抑制剂及其治疗用途
US9169199B2 (en) 2010-12-08 2015-10-27 Lycera Corporation Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof
DK2648511T3 (en) 2010-12-08 2017-09-18 Lycera Corp PYRAZOLYLGUANIDINE-F1F0 ATPASE INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF
US9580391B2 (en) 2012-06-08 2017-02-28 Lycera Corporation Saturated acyl guanidine for inhibition of F1F0-ATPase
EP2866796A4 (en) * 2012-06-08 2015-11-25 Lycera Corp PYRAZOLYL GUANIDINE F1FO ATPASE HEMMER AND THERAPEUTIC USES THEREOF
US9221814B2 (en) 2012-06-08 2015-12-29 Lycera Corporation Heterocyclic guanidine F1F0-atpase inhibitors and therapeutic uses thereof
US9388126B2 (en) 2012-07-19 2016-07-12 Drexel University Sigma receptor ligands and methods of modulating cellular protein homeostasis using same
CN103396349B (zh) * 2013-07-19 2014-12-17 浙江工业大学 一种含1-甲基环己基的酰基硫脲类化合物、制备方法及其应用
CN103351360B (zh) * 2013-07-19 2015-03-25 浙江工业大学 一种含1,3,4-噻二唑基团的酰基硫脲类化合物、制备方法及其应用
WO2015089152A1 (en) * 2013-12-10 2015-06-18 Lycera Corporation N-substituted pyrazolyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof
WO2015089131A1 (en) 2013-12-10 2015-06-18 Lycera Corporation Alkylpyrazolyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof
BR112016013116A8 (pt) 2013-12-10 2020-05-12 Lycera Corp inibidores de trifluorometil pirazolil guanidina f1f0-atpase, seus usos, e composições farmacêuticas
WO2019089902A1 (en) 2017-11-01 2019-05-09 Drexel University Compounds, compositions, and methods for treating diseases

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