AT280290B - Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen - Google Patents

Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Info

Publication number
AT280290B
AT280290B AT1064767A AT1064767A AT280290B AT 280290 B AT280290 B AT 280290B AT 1064767 A AT1064767 A AT 1064767A AT 1064767 A AT1064767 A AT 1064767A AT 280290 B AT280290 B AT 280290B
Authority
AT
Austria
Prior art keywords
diones
benzodiazepine
phenyl
alkyl
preparation
Prior art date
Application number
AT1064767A
Other languages
English (en)
Inventor
C H Boehringer Sohn
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to AT1064767A priority Critical patent/AT280290B/de
Priority to NL6815755A priority patent/NL6815755A/xx
Priority to SE15032/68A priority patent/SE356979B/xx
Priority to ES360410A priority patent/ES360410A1/es
Priority to DK566968AA priority patent/DK124950B/da
Priority to CH1742668A priority patent/CH523265A/de
Priority to BE724364A priority patent/BE724364A/fr
Priority to DE19681810423 priority patent/DE1810423B2/de
Priority to FR1593335D priority patent/FR1593335A/fr
Priority to CH280071A priority patent/CH510035A/de
Priority to IE1425/68A priority patent/IE32504B1/xx
Priority to BR204236/68A priority patent/BR6804236D0/pt
Priority to IL31146A priority patent/IL31146A/en
Priority to GB55844/68A priority patent/GB1173540A/en
Priority to FR183259A priority patent/FR8310M/fr
Application granted granted Critical
Publication of AT280290B publication Critical patent/AT280290B/de
Priority to ES378977A priority patent/ES378977A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT1064767A 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen AT280290B (de)

Priority Applications (16)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen
NL6815755A NL6815755A (de) 1967-11-24 1968-11-05
SE15032/68A SE356979B (de) 1967-11-24 1968-11-06
ES360410A ES360410A1 (es) 1967-11-24 1968-11-19 Procedimiento para la preparacion de 1-fenil - 4 - alcohil-3h-1,4-benzodiazepin-2,5 (1h, 4h)-dionas.
DK566968AA DK124950B (da) 1967-11-24 1968-11-20 Analogifremgangsmåde til fremstilling af 1-phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dioner.
BE724364A BE724364A (de) 1967-11-24 1968-11-22
CH1742668A CH523265A (de) 1967-11-24 1968-11-22 Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3 H-1,4-benzodiazepin-2,5 (1H, 4H)-dionen
DE19681810423 DE1810423B2 (de) 1967-11-24 1968-11-22 1-phenyl-4-alkyl-1,2,4,5-tetrahydro-3h-1,4-benzodiazepin-2,5-dionderivate
FR1593335D FR1593335A (de) 1967-11-24 1968-11-22
CH280071A CH510035A (de) 1967-11-24 1968-11-22 Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-(1H,4H)-dionen
IE1425/68A IE32504B1 (en) 1967-11-24 1968-11-22 Benzodiazepine derivatives
BR204236/68A BR6804236D0 (pt) 1967-11-24 1968-11-22 Processo para a obtencao de 1-fenil-4-alquil-3h 1 4-benzo-diazepin-2 5-1h 4h-dionas
IL31146A IL31146A (en) 1967-11-24 1968-11-24 1,2,4,5-Tetrahydro-H3-1,4-Benzodiazepine-2,5-Discussions, their preparation and pharmaceutical preparations containing them
GB55844/68A GB1173540A (en) 1967-11-24 1968-11-25 Benzodiazepine Derivatives
FR183259A FR8310M (de) 1967-11-24 1969-02-21
ES378977A ES378977A1 (es) 1967-11-24 1970-04-23 Procedimiento para la preparacion de 1-fenil-4-alcohil-3h--1,4-benzodiazepin-2,5 (1h,4h)-dionas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (1)

Publication Number Publication Date
AT280290B true AT280290B (de) 1970-04-10

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Country Status (13)

Country Link
AT (1) AT280290B (de)
BE (1) BE724364A (de)
BR (1) BR6804236D0 (de)
CH (1) CH523265A (de)
DE (1) DE1810423B2 (de)
DK (1) DK124950B (de)
ES (2) ES360410A1 (de)
FR (2) FR1593335A (de)
GB (1) GB1173540A (de)
IE (1) IE32504B1 (de)
IL (1) IL31146A (de)
NL (1) NL6815755A (de)
SE (1) SE356979B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
CA2372150C (en) 1999-04-30 2011-08-30 The Regents Of The University Of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
AU2006203946B2 (en) 2005-01-03 2009-07-23 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
EP1893218A4 (de) 2005-06-01 2011-01-12 Univ Michigan Ungelöste benzodiazepin-zusammensetzungen und verfahren
CA2628193C (en) 2005-11-01 2012-08-14 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
MX2008015488A (es) 2006-06-09 2009-02-12 Univ Michigan Composiciones y metodos relacionados con compuestos novedosos y objetivos de los mismos.
BRPI0808653A2 (pt) 2007-03-09 2014-08-19 Univ Michigan Composições e métodos referindo-se a novos compostos e alvos dos mesmos.
CN101686983A (zh) * 2007-05-10 2010-03-31 Amr科技公司 芳基和杂芳基取代的四氢苯并-1,4-二氮杂䓬及其阻断去甲肾上腺素、多巴胺和5-羟色胺重摄取的用途
ES2614498T3 (es) 2007-09-14 2017-05-31 The Regents Of The University Of Michigan Inhibidores de ATPasa F1F0 y métodos relacionados
AU2008323945B2 (en) 2007-11-06 2013-11-28 The Regents Of The University Of Michigan Benzodiazepinone compounds useful in the treatment of skin conditions
EP2352724B1 (de) 2008-09-11 2015-04-22 The Regents of the University of Michigan Arylguanidine-f1f0-aptase inhibitoren und deren therapeutischen verwendung
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
CA2780333C (en) 2009-11-17 2016-05-24 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
JP5856064B2 (ja) 2009-11-17 2016-02-09 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物
AU2014318748B2 (en) 2013-09-11 2019-02-28 Duquesne University Of The Holy Ghost Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
DE1810423B2 (de) 1973-03-22
IE32504B1 (en) 1973-08-22
SE356979B (de) 1973-06-12
DK124950B (da) 1972-12-11
NL6815755A (de) 1969-05-28
CH523265A (de) 1972-05-31
IL31146A (en) 1972-04-27
IE32504L (en) 1969-05-24
IL31146A0 (en) 1969-01-29
GB1173540A (en) 1969-12-10
BR6804236D0 (pt) 1973-02-08
ES378977A1 (es) 1973-01-16
BE724364A (de) 1969-05-22
FR8310M (de) 1970-11-23
DE1810423C3 (de) 1973-10-11
ES360410A1 (es) 1970-11-01
DE1810423A1 (de) 1969-10-09
FR1593335A (de) 1970-05-25

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