IL31146A - 1,2,4,5-Tetrahydro-H3-1,4-Benzodiazepine-2,5-Discussions, their preparation and pharmaceutical preparations containing them - Google Patents

1,2,4,5-Tetrahydro-H3-1,4-Benzodiazepine-2,5-Discussions, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL31146A
IL31146A IL31146A IL3114668A IL31146A IL 31146 A IL31146 A IL 31146A IL 31146 A IL31146 A IL 31146A IL 3114668 A IL3114668 A IL 3114668A IL 31146 A IL31146 A IL 31146A
Authority
IL
Israel
Prior art keywords
compounds
formula
effected
group
solvent
Prior art date
Application number
IL31146A
Other languages
English (en)
Hebrew (he)
Other versions
IL31146A0 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IL31146A0 publication Critical patent/IL31146A0/xx
Publication of IL31146A publication Critical patent/IL31146A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL31146A 1967-11-24 1968-11-24 1,2,4,5-Tetrahydro-H3-1,4-Benzodiazepine-2,5-Discussions, their preparation and pharmaceutical preparations containing them IL31146A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (2)

Publication Number Publication Date
IL31146A0 IL31146A0 (en) 1969-01-29
IL31146A true IL31146A (en) 1972-04-27

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
IL31146A IL31146A (en) 1967-11-24 1968-11-24 1,2,4,5-Tetrahydro-H3-1,4-Benzodiazepine-2,5-Discussions, their preparation and pharmaceutical preparations containing them

Country Status (13)

Country Link
AT (1) AT280290B (de)
BE (1) BE724364A (de)
BR (1) BR6804236D0 (de)
CH (1) CH523265A (de)
DE (1) DE1810423B2 (de)
DK (1) DK124950B (de)
ES (2) ES360410A1 (de)
FR (2) FR1593335A (de)
GB (1) GB1173540A (de)
IE (1) IE32504B1 (de)
IL (1) IL31146A (de)
NL (1) NL6815755A (de)
SE (1) SE356979B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
EP2359831A3 (de) * 1999-04-30 2012-02-01 The Regents of the University of Michigan Therapeutische Anwendungen proapoptotischer Benzodiazepine
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7144880B2 (en) 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
JP2008528448A (ja) 2005-01-03 2008-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 新規化合物に関連する組成物および方法、ならびにその標的
WO2007053193A2 (en) 2005-06-01 2007-05-10 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
EP1948191B1 (de) 2005-11-01 2013-01-16 The Regents of the University of Michigan Neuartige 1,4-benzodiazepin-2,5-dione mit therapeutischen eigenschaften
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2418206A3 (de) 2006-06-09 2012-06-27 The Regents of the University of Michigan Benzodiazepin-derivate zur behandlung von autoimmunerkrankungen
CA2680017C (en) 2007-03-09 2013-11-12 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US9096546B2 (en) * 2007-05-10 2015-08-04 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
EP2200977B1 (de) 2007-09-14 2016-11-09 The Regents of the University of Michigan F1f0-atpase-inhibitoren und damit in zusammenhang stehende verfahren
MX2010004857A (es) 2007-11-06 2010-07-28 Univ Michigan Compuestos de benzodiazepinona utiles en el tratamiento de afecciones de la piel.
EP2352724B1 (de) 2008-09-11 2015-04-22 The Regents of the University of Michigan Arylguanidine-f1f0-aptase inhibitoren und deren therapeutischen verwendung
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
CN102753544A (zh) 2009-11-17 2012-10-24 密执安大学评议会 具有治疗性能的1，4-苯并二氮杂*-2，5-二酮和相关化合物
WO2011062765A2 (en) 2009-11-17 2011-05-26 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
CA2923835C (en) * 2013-09-11 2022-11-29 The Administrators Of The Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
SE356979B (de) 1973-06-12
NL6815755A (de) 1969-05-28
IE32504L (en) 1969-05-24
BR6804236D0 (pt) 1973-02-08
IL31146A0 (en) 1969-01-29
AT280290B (de) 1970-04-10
ES360410A1 (es) 1970-11-01
DE1810423C3 (de) 1973-10-11
ES378977A1 (es) 1973-01-16
DE1810423B2 (de) 1973-03-22
CH523265A (de) 1972-05-31
BE724364A (de) 1969-05-22
FR1593335A (de) 1970-05-25
DK124950B (da) 1972-12-11
FR8310M (de) 1970-11-23
IE32504B1 (en) 1973-08-22
GB1173540A (en) 1969-12-10
DE1810423A1 (de) 1969-10-09

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