JP2018138049A5 - - Google Patents

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JP2018138049A5
JP2018138049A5 JP2018088729A JP2018088729A JP2018138049A5 JP 2018138049 A5 JP2018138049 A5 JP 2018138049A5 JP 2018088729 A JP2018088729 A JP 2018088729A JP 2018088729 A JP2018088729 A JP 2018088729A JP 2018138049 A5 JP2018138049 A5 JP 2018138049A5
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JP6603964B2 (ja
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JP2018088729A 2011-04-26 2018-05-02 組織再生を誘導するためのペプチドとその利用 Active JP6603964B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2011098270 2011-04-26
JP2011098270 2011-04-26
JP2011219454 2011-10-03
JP2011219454 2011-10-03

Related Parent Applications (1)

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JP2016214996A Division JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用

Related Child Applications (1)

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JP2019175276A Division JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用

Publications (3)

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JP2018138049A JP2018138049A (ja) 2018-09-06
JP2018138049A5 true JP2018138049A5 (enExample) 2018-12-13
JP6603964B2 JP6603964B2 (ja) 2019-11-13

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JP2013511983A Active JP6069191B2 (ja) 2011-04-26 2012-04-03 組織再生を誘導するためのペプチドとその利用
JP2016214996A Active JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用
JP2018088729A Active JP6603964B2 (ja) 2011-04-26 2018-05-02 組織再生を誘導するためのペプチドとその利用
JP2019175276A Pending JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用
JP2021129955A Pending JP2021191271A (ja) 2011-04-26 2021-08-06 組織再生を誘導するためのペプチドとその利用
JP2023084251A Pending JP2023106525A (ja) 2011-04-26 2023-05-23 組織再生を誘導するためのペプチドとその利用

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JP2013511983A Active JP6069191B2 (ja) 2011-04-26 2012-04-03 組織再生を誘導するためのペプチドとその利用
JP2016214996A Active JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用

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JP2019175276A Pending JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用
JP2021129955A Pending JP2021191271A (ja) 2011-04-26 2021-08-06 組織再生を誘導するためのペプチドとその利用
JP2023084251A Pending JP2023106525A (ja) 2011-04-26 2023-05-23 組織再生を誘導するためのペプチドとその利用

Country Status (12)

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US (4) US10364276B2 (enExample)
EP (2) EP2703487B1 (enExample)
JP (6) JP6069191B2 (enExample)
KR (2) KR102113809B1 (enExample)
CN (3) CN103687946B (enExample)
AU (4) AU2012248676B2 (enExample)
CA (1) CA2834255C (enExample)
DK (2) DK2703487T3 (enExample)
ES (2) ES2788394T3 (enExample)
PL (2) PL3358011T3 (enExample)
PT (2) PT2703487T (enExample)
WO (1) WO2012147470A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110017371A (ko) 2008-04-30 2011-02-21 가부시키가이샤 제노믹스 생체내 기능적 세포의 고효율 채취법
KR20120135190A (ko) 2009-10-28 2012-12-12 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제
PL2913058T3 (pl) 2012-10-25 2018-04-30 Genomix Co., Ltd. Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1
CN104955470B (zh) 2012-10-25 2017-06-16 吉诺米克斯股份有限公司 利用了hmgb1片段的针对脊髄损伤的新型治疗方法
CN113648323A (zh) * 2013-06-05 2021-11-16 再生疗法有限公司 用于哺乳动物物种中诱导性组织再生的组合物和方法
CN107530451A (zh) 2015-05-07 2018-01-02 南佛罗里达大学 用于天使人综合征的基因治疗方法的修饰的ube3a基因
EP3387112A4 (en) 2015-12-07 2019-08-21 BioTime, Inc. METHOD FOR RECONNECTING BROWN FAT CELLS DERIVED FROM VARIOUS PLURIPOTENT STEM CELLS
CN106995796A (zh) * 2016-01-26 2017-08-01 李建业 基于细胞因子的细胞处理方法、试剂盒及冻干粉
WO2017189988A1 (en) * 2016-04-29 2017-11-02 Araim Pharmaceuticals, Inc. Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage
KR20190059297A (ko) 2016-09-21 2019-05-30 스티븐 에이치. 쏜 고-이동성 군 박스 1 돌연변이체
BR112019014921A2 (pt) 2017-01-27 2020-03-31 StemRIM Inc. Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica
CN110621331A (zh) * 2017-04-07 2019-12-27 斯特姆里姆有限公司 纤维化疾病的治疗药物
CA3059544A1 (en) 2017-04-25 2018-11-01 Shionogi & Co., Ltd. Peptide for inducing regeneration of tissue, and use thereof
JPWO2019107530A1 (ja) * 2017-12-01 2020-11-26 株式会社ステムリム 炎症性腸疾患の治療薬
US12421498B2 (en) 2017-12-01 2025-09-23 StemRIM Inc. Ectodermal mesenchymal stem cells and method for producing same
WO2019156137A1 (ja) 2018-02-08 2019-08-15 株式会社ステムリム 乾癬の治療薬
US20220009976A1 (en) * 2018-10-05 2022-01-13 StemRIM Inc. Peptide Possessing Mesenchymal-Stem-Cell Mobilizing Activity
US12304933B2 (en) 2018-10-05 2025-05-20 StemRIM Inc. Disease treatment drug based on mesenchymal-stem-cell mobilization
EP3865179B1 (en) 2018-10-25 2025-07-23 The University of Osaka Hmgb1 derived peptide for treating or preventing a cartilage disorder
US20220175940A1 (en) * 2019-03-26 2022-06-09 Niigata University Peptide and use thereof
CN109957015A (zh) * 2019-04-01 2019-07-02 中国人民解放军海军军医大学国家肝癌科学中心 一种hmgb1封闭性抗体的制备方法及其应用
WO2021094983A1 (en) * 2019-11-12 2021-05-20 Oxford University Innovation Limited Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof
IL296982B1 (en) * 2020-04-03 2025-12-01 Stemrim Inc Peptide having mesenchymal stem cell mobilizing activity
EP4147711A4 (en) * 2020-04-20 2024-04-24 Shionogi & Co., Ltd Formulation containing hmgb1 partial peptide
EP4138878A4 (en) * 2020-04-22 2024-03-20 Chulalongkorn University A composition and a method of rejuvenating dna and preventing dna damage
EP4257703A4 (en) * 2020-12-07 2025-06-04 Samsung Life Public Welfare Foundation Method for selecting mesenchymal stem cells with improved self-sustainability and thereby selected mesenchymal stem cells
WO2022243932A1 (en) * 2021-05-19 2022-11-24 Oxford University Innovation Limited Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof
KR20240070640A (ko) 2021-09-30 2024-05-21 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 지방간 및 비알코올성 지방간염의 치료약
CN116983471B (zh) * 2023-06-07 2024-03-08 华中科技大学同济医学院附属协和医院 一种基于α-螺旋双亲性多肽的超分子共组装凝胶的制备方法及应用

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5238680B2 (enExample) 1972-12-27 1977-09-30
US4732155A (en) 1985-08-27 1988-03-22 The Children's Medical Center Corporation Implantable chemoattractant system
US5658894A (en) 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5661127A (en) 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
JP3018313B2 (ja) 1996-02-23 2000-03-13 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
US20040031072A1 (en) 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
DE60042828D1 (de) 1999-07-28 2009-10-08 Univ R Nicotinrezeptoragonisten in stammzellen und vorlaüferzellinduktion
WO2001032129A2 (en) 1999-11-05 2001-05-10 Gerigene Medical Corporation Augmentation and repair of age-related soft tissue defects
EP1114862A3 (de) 1999-11-17 2003-08-06 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen
AU4328801A (en) 2000-02-24 2001-09-03 Xcyte Therapies Inc Simultaneous stimulation and concentration of cells
JP3421741B2 (ja) 2000-05-18 2003-06-30 筑波大学長 人工骨髄、血球細胞の増殖方法
US20040191246A1 (en) 2003-02-26 2004-09-30 Connelly Patrick R. Process for in vivo treatment of specific biological targets in bodily fluid
US7754217B2 (en) 2001-03-16 2010-07-13 Bio3 Research Srl HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
DE10121254A1 (de) 2001-04-30 2002-11-07 Switch Biotech Ag MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind
EP1390058A2 (en) 2001-04-30 2004-02-25 Switch Biotech Aktiengesellschaft Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
HUP0500042A3 (en) 2001-05-15 2010-01-28 Long Island Jewish Res Inst Use of hmg fragments as anti-inflammatory agents
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
US20040265971A1 (en) 2001-11-19 2004-12-30 Hidetaka Sato Drug mobilizing pluripotent stem cells from tissue into peripheral blood
KR100930139B1 (ko) 2001-12-07 2009-12-07 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
FR2833609B1 (fr) 2001-12-19 2004-12-03 Natural Implant Dispositif de prelevement cellulaire ou tissulaire en phase active et utilisations
JP2005537253A (ja) 2002-07-03 2005-12-08 フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール 組織損傷の治療におけるおよび/または組織修復を促進するためのhmgb1の使用
DE60327075D1 (de) 2002-07-05 2009-05-20 Univ Laval Der entzündungsreaktionen
GB0226251D0 (en) 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
US20040156851A1 (en) 2002-11-20 2004-08-12 Critical Therapeutics, Inc. HMGB1 combination therapies
JP2006510619A (ja) 2002-11-20 2006-03-30 クリティカル セラピューティクス,インコーポレイテッド 抗炎症剤としてのhmgb断片の使用
EP1579221A2 (de) 2003-01-03 2005-09-28 Alcedo Biotech GmbH Verwendungen von hmgb, hmgn, hmga proteinen
DE602004017148D1 (de) 2003-03-28 2008-11-27 Univ Laval S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung
CN1193092C (zh) 2003-03-28 2005-03-16 浙江大学 骨髓间充质干细胞分离和体外扩增培养方法
US20090069227A9 (en) 2003-04-29 2009-03-12 Capogrossi Maurizio C Use of HMGB1 to promote stem cell migration and/or proliferation
US20050014255A1 (en) 2003-05-29 2005-01-20 Board Of Regents, The University Of Texas System Stem cells for clinical and commercial uses
WO2005025604A2 (en) 2003-09-10 2005-03-24 The General Hospital Corporation Use of hmgb and hmgb fragments to decrease specific immune response
CA2882022A1 (en) 2003-09-11 2005-03-24 Walter Newman Monoclonal antibodies against hmgb1
ITRM20040058A1 (it) 2004-02-03 2004-05-03 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali.
CA2574548A1 (en) 2004-07-20 2006-01-26 Fondazione Centro San Raffaele Del Monte Tabor Use of hmgb1 for wound healing
MX2007001155A (es) 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
KR101249287B1 (ko) * 2004-09-03 2013-04-01 크리어빌리스 쎄라퓨틱스 에스.피.에이. 인간 및 비­인간 hmgb1 box­a의 단백질분해효소내성 돌연변이 및 그들의 치료/진단 용도
CN101132811B (zh) * 2004-10-22 2012-05-30 米迪缪尼有限公司 抗hmgb1的高亲和力抗体及其用法
KR100593397B1 (ko) 2004-10-27 2006-06-28 한국원자력연구소 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제
WO2006047820A1 (en) 2004-11-01 2006-05-11 Newsouth Innovations Pty Limited Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation
ITRM20050032A1 (it) 2005-01-21 2006-07-22 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.
US9782439B2 (en) 2005-01-27 2017-10-10 Japan Health Sciences Foundation Cell sheet containing mesenchymal stem cells
CN101146559B (zh) 2005-03-23 2012-09-05 生物安全股份有限公司 用于再生医学的收集、处理和移植包括成人干细胞的细胞亚群的集成系统
KR100775958B1 (ko) * 2005-03-30 2007-11-13 김정문 조직재생 기능을 가지는 비활성 폴리펩티드 및 그 제조방법
WO2006114805A2 (en) 2005-04-28 2006-11-02 Fondazione Centro San Raffaele Del Monte Tabor Use of hmgb2 and hmgb3 proteins for medical applications
US20100280493A1 (en) 2005-06-23 2010-11-04 Asha Nayak Methods and Systems for Treating Injured Cardiac Tissue
WO2007015546A1 (ja) 2005-08-04 2007-02-08 Genomix Co., Ltd 間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法
WO2007031100A1 (en) 2005-09-14 2007-03-22 Ostini, Marco Active immunotherapy of life-threatening systemic inflammation
WO2007061762A2 (en) * 2005-11-18 2007-05-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt And Human Services Non-viral gene delivery complex
WO2007130725A2 (en) 2006-02-06 2007-11-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of hmgb1 for protection against ischemia reperfusion injury
JP4982739B2 (ja) 2006-06-01 2012-07-25 国立大学法人 東京医科歯科大学 ポリグルタミン病の予防・治療剤
ES2396220T3 (es) 2006-08-11 2013-02-20 Ono Pharmaceutical Co., Ltd. Anticuerpos monoclonales frente al factor 1 derivado del estroma (SDF-1)
CA2663300C (en) 2006-09-15 2014-10-07 Creabilis Therapeutics S.P.A. Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1
SI2068935T1 (sl) * 2006-09-15 2011-07-29 Creabilis Therapeutics S R L Polimerni konjugati od Box-A od HMGB1 in Box-A variante od HMGB1
AU2007315073A1 (en) 2006-10-30 2008-05-08 Genomix Co., Ltd. Pharmaceuticals that promote functional regeneration of damaged tissues
CA2629652A1 (en) 2007-04-24 2008-10-24 Yaojiong Wu Compositions for preventing or treating skin defects and methods of use thereof
US8114668B2 (en) 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
AU2009240885A1 (en) 2008-04-30 2009-11-05 Genomix Co., Ltd. Pharmaceutical agent for promoting the functional regeneration of damaged tissue
KR20110017371A (ko) * 2008-04-30 2011-02-21 가부시키가이샤 제노믹스 생체내 기능적 세포의 고효율 채취법
WO2009133939A1 (ja) 2008-04-30 2009-11-05 株式会社ジェノミックス 末梢循環への骨髄由来多能性幹細胞動員薬
CA2777663A1 (en) 2009-10-16 2011-04-21 University Of Medicine And Dentistry Of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
KR20120135190A (ko) 2009-10-28 2012-12-12 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제
CN102443064A (zh) 2011-11-03 2012-05-09 刘誉 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用
CN104955470B (zh) 2012-10-25 2017-06-16 吉诺米克斯股份有限公司 利用了hmgb1片段的针对脊髄损伤的新型治疗方法
PL2913058T3 (pl) 2012-10-25 2018-04-30 Genomix Co., Ltd. Nowy sposób leczenia zawału mięśnia sercowego przy użyciu fragmentu HMGB1

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