JP2023518596A5 - - Google Patents
Info
- Publication number
- JP2023518596A5 JP2023518596A5 JP2022558063A JP2022558063A JP2023518596A5 JP 2023518596 A5 JP2023518596 A5 JP 2023518596A5 JP 2022558063 A JP2022558063 A JP 2022558063A JP 2022558063 A JP2022558063 A JP 2022558063A JP 2023518596 A5 JP2023518596 A5 JP 2023518596A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- protein
- polynucleotide
- split
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20382236.6 | 2020-03-26 | ||
| EP20382236.6A EP3885440A1 (en) | 2020-03-26 | 2020-03-26 | Split inteins and their uses |
| PCT/EP2021/058016 WO2021191447A1 (en) | 2020-03-26 | 2021-03-26 | Split inteins and their uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023518596A JP2023518596A (ja) | 2023-05-02 |
| JP2023518596A5 true JP2023518596A5 (enExample) | 2024-04-05 |
Family
ID=70292931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022558063A Pending JP2023518596A (ja) | 2020-03-26 | 2021-03-26 | スプリットインテイン及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230116688A1 (enExample) |
| EP (2) | EP3885440A1 (enExample) |
| JP (1) | JP2023518596A (enExample) |
| KR (1) | KR20220160052A (enExample) |
| CN (1) | CN115698307A (enExample) |
| AU (1) | AU2021241899A1 (enExample) |
| BR (1) | BR112022019167A2 (enExample) |
| CA (1) | CA3175696A1 (enExample) |
| IL (1) | IL296712A (enExample) |
| WO (1) | WO2021191447A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019336245B2 (en) | 2018-09-07 | 2026-02-26 | Beam Therapeutics Inc. | Compositions and methods for delivering a nucleobase editing system |
| CA3152679A1 (en) * | 2019-08-28 | 2021-03-04 | The Trustees Of Princeton University | Atypical split inteins and uses thereof |
| CN116096905A (zh) | 2020-02-21 | 2023-05-09 | 阿库斯股份有限公司 | 用于治疗人受试者的非年龄相关性听力损伤的组合物和方法 |
| EP4424714A4 (en) * | 2021-10-29 | 2025-10-15 | Shanghai Sinobay Biotechnology Co Ltd | Condition-Controlled Splicable Chimeric Antigen Receptor Molecule and Its Use |
| EP4527933A4 (en) * | 2022-05-17 | 2025-12-24 | Eye & Ent Hospital Of Fudan Univ | DUAL-SUPPORT SYSTEM FOR THE TREATMENT OF HEARING LOSS, AND ITS USE |
| KR20250141200A (ko) * | 2023-02-01 | 2025-09-26 | 알렌 인스티튜트 | 전압-게이팅 나트륨 채널 기능의 인테인 매개 재구성 |
| WO2024251077A1 (zh) | 2023-06-07 | 2024-12-12 | 北京中因科技有限公司 | 表达盒组合及其应用 |
| WO2025038955A1 (en) * | 2023-08-16 | 2025-02-20 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Systems and methods for improving safety of split intein aav mediated gene therapy |
| AU2024338787A1 (en) | 2023-09-04 | 2026-03-19 | Splicebio, Sl | Use of split intein for the treatment of scn1a associated disease |
| WO2025153705A1 (en) | 2024-01-18 | 2025-07-24 | Splicebio, Sl | Use of split intein for the treatment of myo7a-associated disease |
| WO2025193938A1 (en) * | 2024-03-13 | 2025-09-18 | Oregon Health & Science University | Delivery of type iv collagen alpha chain using a split intein dual aav vector |
| WO2026013288A1 (en) | 2024-07-12 | 2026-01-15 | Splicebio, Sl | Split intein for use in the treatment of cep290-associated disease |
| WO2026057767A1 (en) | 2024-09-13 | 2026-03-19 | Splicebio, Sl | Use of split intein for the treatment of abca3-associated disease |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| WO2007127428A2 (en) | 2006-04-28 | 2007-11-08 | University Of Florida Research Foundation, Inc. | Double-stranded/self-complementary vectors with a truncated cba promoter and methods of gene delivery |
| US20180327779A1 (en) * | 2015-03-03 | 2018-11-15 | Fondazione Telethon (IT/IT) | Multiple vector system and uses thereof |
| US11203621B2 (en) * | 2015-06-19 | 2021-12-21 | Riken | PH-responsive proteolysis probe |
| WO2017132580A2 (en) * | 2016-01-29 | 2017-08-03 | The Trustees Of Princeton University | Split inteins with exceptional splicing activity |
| JP2022512718A (ja) * | 2018-10-15 | 2022-02-07 | フォンダッツィオーネ・テレソン | インテインタンパク質及びその使用 |
-
2020
- 2020-03-26 EP EP20382236.6A patent/EP3885440A1/en active Pending
-
2021
- 2021-03-26 JP JP2022558063A patent/JP2023518596A/ja active Pending
- 2021-03-26 IL IL296712A patent/IL296712A/en unknown
- 2021-03-26 KR KR1020227037261A patent/KR20220160052A/ko active Pending
- 2021-03-26 CA CA3175696A patent/CA3175696A1/en active Pending
- 2021-03-26 CN CN202180038835.4A patent/CN115698307A/zh active Pending
- 2021-03-26 US US17/914,212 patent/US20230116688A1/en active Pending
- 2021-03-26 AU AU2021241899A patent/AU2021241899A1/en active Pending
- 2021-03-26 BR BR112022019167A patent/BR112022019167A2/pt unknown
- 2021-03-26 EP EP21713447.7A patent/EP4127194A1/en active Pending
- 2021-03-26 WO PCT/EP2021/058016 patent/WO2021191447A1/en not_active Ceased
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