JP2018046872A5 - - Google Patents
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- JP2018046872A5 JP2018046872A5 JP2018000123A JP2018000123A JP2018046872A5 JP 2018046872 A5 JP2018046872 A5 JP 2018046872A5 JP 2018000123 A JP2018000123 A JP 2018000123A JP 2018000123 A JP2018000123 A JP 2018000123A JP 2018046872 A5 JP2018046872 A5 JP 2018046872A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- antigen
- domain
- protein according
- antigen binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36990910P | 2010-08-02 | 2010-08-02 | |
| US61/369,909 | 2010-08-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016009916A Division JP2016054746A (ja) | 2010-08-02 | 2016-01-21 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018212094A Division JP6759303B2 (ja) | 2010-08-02 | 2018-11-12 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018046872A JP2018046872A (ja) | 2018-03-29 |
| JP2018046872A5 true JP2018046872A5 (https=) | 2018-12-20 |
| JP7078400B2 JP7078400B2 (ja) | 2022-05-31 |
Family
ID=44543797
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523258A Active JP6146913B2 (ja) | 2010-08-02 | 2011-08-02 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2016009916A Withdrawn JP2016054746A (ja) | 2010-08-02 | 2016-01-21 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2018000123A Active JP7078400B2 (ja) | 2010-08-02 | 2018-01-04 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2018212094A Active JP6759303B2 (ja) | 2010-08-02 | 2018-11-12 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2020023076A Active JP7110257B2 (ja) | 2010-08-02 | 2020-02-14 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2021084769A Pending JP2021119792A (ja) | 2010-08-02 | 2021-05-19 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523258A Active JP6146913B2 (ja) | 2010-08-02 | 2011-08-02 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2016009916A Withdrawn JP2016054746A (ja) | 2010-08-02 | 2016-01-21 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018212094A Active JP6759303B2 (ja) | 2010-08-02 | 2018-11-12 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2020023076A Active JP7110257B2 (ja) | 2010-08-02 | 2020-02-14 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
| JP2021084769A Pending JP2021119792A (ja) | 2010-08-02 | 2021-05-19 | Ｖｌドメインを含む結合タンパク質を作製するマウス |
Country Status (27)
| Country | Link |
|---|---|
| US (8) | US9516868B2 (https=) |
| EP (3) | EP3960865A1 (https=) |
| JP (6) | JP6146913B2 (https=) |
| KR (4) | KR102434557B1 (https=) |
| CN (4) | CN103154255B (https=) |
| AU (1) | AU2011285919C1 (https=) |
| BR (1) | BR112013002695B1 (https=) |
| CA (2) | CA3250882A1 (https=) |
| CY (1) | CY1118562T1 (https=) |
| DK (1) | DK2601298T3 (https=) |
| ES (1) | ES2612459T3 (https=) |
| HK (1) | HK1217511A1 (https=) |
| HR (1) | HRP20170322T1 (https=) |
| HU (1) | HUE031903T2 (https=) |
| IL (4) | IL271804B2 (https=) |
| LT (1) | LT2601298T (https=) |
| MX (5) | MX350591B (https=) |
| MY (1) | MY172618A (https=) |
| NZ (2) | NZ606824A (https=) |
| PL (1) | PL2601298T3 (https=) |
| PT (1) | PT2601298T (https=) |
| RS (1) | RS55495B1 (https=) |
| RU (2) | RU2750219C2 (https=) |
| SG (3) | SG10201912639SA (https=) |
| SI (1) | SI2601298T1 (https=) |
| SM (2) | SMT201700023T1 (https=) |
| WO (1) | WO2012018764A1 (https=) |
Families Citing this family (89)
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| SI2501817T2 (sl) | 2010-02-08 | 2021-09-30 | Regeneron Pharmaceuticals, Inc. | Miš z navadno lahko verigo |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| JP6482757B2 (ja) | 2010-07-26 | 2019-03-13 | トリアンニ インコーポレイテッドＴｒｉａｎｎｉ，Ｉｎｃ． | トランスジェニック動物および使用方法 |
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| RS59728B1 (sr) | 2011-08-05 | 2020-02-28 | Regeneron Pharma | Humanizovani miševi univerzalnog lakog lanca |
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| BR112014006394A2 (pt) | 2011-09-19 | 2017-03-28 | Kymab Ltd | manipulação de diversidade genética de imunoglobulina e terapêuticos multi-anticorpos |
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| KR20160098514A (ko) | 2011-10-17 | 2016-08-18 | 리제너론 파아마슈티컬스, 인크. | 제한된 면역글로불린 중쇄 마우스 |
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| RU2664181C2 (ru) | 2011-12-20 | 2018-08-15 | Регенерон Фармасьютикалз, Инк. | Мыши с гуманизированной легкой цепью |
| RS62023B1 (sr) * | 2012-02-01 | 2021-07-30 | Regeneron Pharma | Humanizovani glodari koji eksprimiraju teške lance koji sadrže vl domene |
| EP2825653A4 (en) | 2012-03-14 | 2016-01-20 | Innovative Targeting Solutions Inc | PRODUCTION OF TARGETED SEQUENCE DIVERSITY IN FUSION PROTEINS |
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| US10251377B2 (en) | 2012-03-28 | 2019-04-09 | Kymab Limited | Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies |
| PT3597037T (pt) | 2012-06-12 | 2021-06-01 | Regeneron Pharma | Animais não humanos humanizados com lócus de cadeia pesada de imunoglobulina restrito |
| US20150203591A1 (en) | 2012-08-02 | 2015-07-23 | Regeneron Pharmaceuticals, Inc. | Mutivalent antigen-binding proteins |
| EP2840892B1 (en) | 2013-02-20 | 2018-04-18 | Regeneron Pharmaceuticals, Inc. | Non-human animals with modified immunoglobulin heavy chain sequences |
| WO2014160202A1 (en) * | 2013-03-13 | 2014-10-02 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| MX379256B (es) | 2013-03-15 | 2025-03-10 | Regeneron Pharma | Moleculas biologicamente activas, conjugados de las mismas, y usos terapeuticos. |
| US9788534B2 (en) | 2013-03-18 | 2017-10-17 | Kymab Limited | Animal models and therapeutic molecules |
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| US11707056B2 (en) | 2013-05-02 | 2023-07-25 | Kymab Limited | Animals, repertoires and methods |
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| JP2020146318A (ja) * | 2019-03-14 | 2020-09-17 | 株式会社三洋物産 | 遊技機 |
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