JP2021530251A5 - - Google Patents

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Publication number
JP2021530251A5
JP2021530251A5 JP2021526401A JP2021526401A JP2021530251A5 JP 2021530251 A5 JP2021530251 A5 JP 2021530251A5 JP 2021526401 A JP2021526401 A JP 2021526401A JP 2021526401 A JP2021526401 A JP 2021526401A JP 2021530251 A5 JP2021530251 A5 JP 2021530251A5
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JP
Japan
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JP2021526401A
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Japanese (ja)
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JP2021530251A (ja
JPWO2020018852A5 (https=
JP7513605B2 (ja
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Priority claimed from PCT/US2019/042493 external-priority patent/WO2020018852A2/en
Publication of JP2021530251A publication Critical patent/JP2021530251A/ja
Publication of JPWO2020018852A5 publication Critical patent/JPWO2020018852A5/ja
Publication of JP2021530251A5 publication Critical patent/JP2021530251A5/ja
Priority to JP2024103530A priority Critical patent/JP2024133536A/ja
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JP2021526401A 2018-07-18 2019-07-18 新規な抗体ならびにそれを調製および使用するための方法 Active JP7513605B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024103530A JP2024133536A (ja) 2018-07-18 2024-06-27 新規な抗体ならびにそれを調製および使用するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862700174P 2018-07-18 2018-07-18
US62/700,174 2018-07-18
US201962792798P 2019-01-15 2019-01-15
US62/792,798 2019-01-15
PCT/US2019/042493 WO2020018852A2 (en) 2018-07-18 2019-07-18 Novel antibodies and methods for making and using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024103530A Division JP2024133536A (ja) 2018-07-18 2024-06-27 新規な抗体ならびにそれを調製および使用するための方法

Publications (4)

Publication Number Publication Date
JP2021530251A JP2021530251A (ja) 2021-11-11
JPWO2020018852A5 JPWO2020018852A5 (https=) 2023-03-10
JP2021530251A5 true JP2021530251A5 (https=) 2023-03-10
JP7513605B2 JP7513605B2 (ja) 2024-07-09

Family

ID=69165232

Family Applications (2)

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JP2021526401A Active JP7513605B2 (ja) 2018-07-18 2019-07-18 新規な抗体ならびにそれを調製および使用するための方法
JP2024103530A Pending JP2024133536A (ja) 2018-07-18 2024-06-27 新規な抗体ならびにそれを調製および使用するための方法

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JP2024103530A Pending JP2024133536A (ja) 2018-07-18 2024-06-27 新規な抗体ならびにそれを調製および使用するための方法

Country Status (5)

Country Link
US (2) US11505618B2 (https=)
EP (1) EP3824096A4 (https=)
JP (2) JP7513605B2 (https=)
CN (1) CN112513093B (https=)
WO (1) WO2020018852A2 (https=)

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US11505618B2 (en) * 2018-07-18 2022-11-22 Askgene Pharma Inc. Antibodies and methods for making and using the same
CA3128502A1 (en) 2019-02-01 2020-08-06 Novarock Biotherapeutics, Ltd. Anti-claudin 18 antibodies and methods of use thereof
WO2021160154A1 (zh) * 2020-02-10 2021-08-19 上海诗健生物科技有限公司 Cldn18.2抗体及其用途
IL298184A (en) * 2020-05-15 2023-01-01 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Antibody drug conjugate, preparation method therefor and use thereof
WO2022012559A1 (zh) * 2020-07-13 2022-01-20 上海君实生物医药科技股份有限公司 抗cldn-18.2抗体及其用途
CN113929780A (zh) * 2020-07-13 2022-01-14 北京凯因科技股份有限公司 一种结合密蛋白的用于治疗癌症的人源化抗体
CN111704669B (zh) * 2020-07-13 2022-05-13 北京凯因科技股份有限公司 一种用于治疗晚期胃癌的抗cldn18全人源化抗体
US20240034784A1 (en) * 2020-09-30 2024-02-01 Nanjing GenScript Biotech Co., Ltd. Antibodies targeting human claudin 18.2 and uses thereof
CN114504642B (zh) * 2020-11-17 2026-03-27 江苏奥赛康生物医药有限公司 一种含抗cldn18.2抗体的液体药物组合物
WO2022122709A1 (en) 2020-12-07 2022-06-16 Sotio Biotech A.S. Antibody-drug conjugates based on humanized cldn18.2 antibodies
CA3199830A1 (en) 2020-12-23 2022-06-30 Lukas BAMMERT Tumor-specific claudin 18.2 antibody-drug conjugates
CN114805571B (zh) * 2021-01-28 2023-08-25 广西鹭港生物医药科技有限公司 抗cldn18.2抗体及其应用
EP4299593A4 (en) * 2021-04-02 2025-12-10 Oricell Therapeutics Co Ltd CLDN18.2 ANTIGEN-BINDING PROTEIN AND ITS USE
CN115611983A (zh) * 2021-07-14 2023-01-17 三优生物医药(上海)有限公司 Cldn18.2结合分子及其用途
WO2024137619A1 (en) 2022-12-20 2024-06-27 Bolt Biotherapeutics, Inc. Anti-claudin, bis-benzimid azole sting agonist immunoconjugates, and uses thereof
KR20250129814A (ko) 2023-01-18 2025-08-29 타이리간드 바이오사이언스 (상하이) 리미티드 항체-약물 접합체 및 이의 용도
WO2024173387A1 (en) 2023-02-14 2024-08-22 Bolt Biotherapeutics, Inc. Aza-benzazepine immunoconjugates, and uses thereof
EP4716702A2 (en) * 2023-05-22 2026-04-01 SystImmune, Inc. Anti-claudin18.2 antibody and method of making and using thereof
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025076127A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025082356A1 (zh) * 2023-10-16 2025-04-24 江苏奥赛康生物医药有限公司 Cldn18_2抗体与化学治疗药物的组合及其应用
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2026050213A1 (en) 2024-08-27 2026-03-05 Usbolt Biotherapeutics, Inc. Tlr agonist immunoconjugates and uses thereof

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
EP1790664A1 (en) * 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
WO2013167153A1 (en) * 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
WO2013174404A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014127785A1 (en) * 2013-02-20 2014-08-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014146672A1 (en) * 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2016165762A1 (en) * 2015-04-15 2016-10-20 Ganymed Pharmaceuticals Ag Drug conjugates comprising antibodies against claudin 18.2
WO2018026742A1 (en) * 2016-08-01 2018-02-08 Askgene Pharma Inc. Novel antibody-albumin-drug conjugates (aadc) and methods for using them
WO2018054484A1 (en) * 2016-09-23 2018-03-29 Biontech Ag Bispecific trivalent antibodies binding to claudin 6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases
WO2019173832A2 (en) * 2018-03-09 2019-09-12 AskGene Pharma, Inc. Novel cytokine prodrugs
US11505618B2 (en) * 2018-07-18 2022-11-22 Askgene Pharma Inc. Antibodies and methods for making and using the same

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