JP2021522162A5 - - Google Patents
Info
- Publication number
- JP2021522162A5 JP2021522162A5 JP2020556851A JP2020556851A JP2021522162A5 JP 2021522162 A5 JP2021522162 A5 JP 2021522162A5 JP 2020556851 A JP2020556851 A JP 2020556851A JP 2020556851 A JP2020556851 A JP 2020556851A JP 2021522162 A5 JP2021522162 A5 JP 2021522162A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- domain
- ror
- binding molecule
- sequences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023172867A JP2023168551A (ja) | 2018-04-18 | 2023-10-04 | 抗ｒｏｒ抗体構築物 |
| JP2025117193A JP2025137618A (ja) | 2018-04-18 | 2025-07-11 | 抗ｒｏｒ抗体構築物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862659635P | 2018-04-18 | 2018-04-18 | |
| US62/659,635 | 2018-04-18 | ||
| PCT/US2019/028051 WO2019204564A1 (en) | 2018-04-18 | 2019-04-18 | Anti-ror antibody constructs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023172867A Division JP2023168551A (ja) | 2018-04-18 | 2023-10-04 | 抗ｒｏｒ抗体構築物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021522162A JP2021522162A (ja) | 2021-08-30 |
| JP2021522162A5 true JP2021522162A5 (https=) | 2022-04-25 |
Family
ID=68239890
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020556851A Pending JP2021522162A (ja) | 2018-04-18 | 2019-04-18 | 抗ｒｏｒ抗体構築物 |
| JP2023172867A Withdrawn JP2023168551A (ja) | 2018-04-18 | 2023-10-04 | 抗ｒｏｒ抗体構築物 |
| JP2025117193A Pending JP2025137618A (ja) | 2018-04-18 | 2025-07-11 | 抗ｒｏｒ抗体構築物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023172867A Withdrawn JP2023168551A (ja) | 2018-04-18 | 2023-10-04 | 抗ｒｏｒ抗体構築物 |
| JP2025117193A Pending JP2025137618A (ja) | 2018-04-18 | 2025-07-11 | 抗ｒｏｒ抗体構築物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US12084496B2 (https=) |
| EP (1) | EP3797122A4 (https=) |
| JP (3) | JP2021522162A (https=) |
| KR (1) | KR20200143470A (https=) |
| CN (1) | CN112384533A (https=) |
| AU (1) | AU2019256431B2 (https=) |
| BR (1) | BR112020021269A2 (https=) |
| CA (1) | CA3097704A1 (https=) |
| EA (1) | EA202092202A1 (https=) |
| IL (2) | IL316574A (https=) |
| MX (4) | MX2020010881A (https=) |
| MY (1) | MY207121A (https=) |
| PH (1) | PH12020551716A1 (https=) |
| SG (1) | SG11202010235QA (https=) |
| WO (1) | WO2019204564A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110177805B (zh) * | 2016-10-19 | 2024-04-02 | 英温拉公司 | 抗体构建体 |
| EP4200336A4 (en) * | 2020-08-24 | 2024-09-25 | Epimab Biotherapeutics (HK) Limited | Anti-ror1 antibodies and related bispecific binding proteins |
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| CN118103070A (zh) * | 2021-08-09 | 2024-05-28 | 默克专利有限公司 | 解偶联t细胞介导的肿瘤细胞毒性与促炎细胞因子释放的蛋白质 |
| IL312204A (en) | 2021-10-28 | 2024-06-01 | Lyell Immunopharma Inc | Methods for culturing cells expressing ror1-binding protein |
| US20230295276A1 (en) * | 2022-03-18 | 2023-09-21 | Novascope Biochips Inc. | Antibody for porcine reproductive and respiratory syndrome virus and uses thereof |
| CA3259758A1 (en) * | 2022-06-30 | 2024-01-04 | Sutro Biopharma, Inc. | Anti-ROR1 antibodies and antibody conjugates, compositions comprising anti-ROR1 antibodies or antibody conjugates, and methods of manufacturing and using anti-ROR1 antibodies and antibody conjugates |
| WO2024207177A1 (en) * | 2023-04-04 | 2024-10-10 | Genequantum Healthcare (Suzhou) Co., Ltd. | Antibody, linkers, payload, conjugates and applications thereof |
| KR20240016216A (ko) * | 2022-07-26 | 2024-02-06 | (주)에임드바이오 | 항-ror1 항체 및 이의 용도 |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| GB202216284D0 (en) * | 2022-11-02 | 2022-12-14 | Ucl Business Ltd | Self-regulation |
| AU2023409023A1 (en) * | 2022-12-20 | 2025-07-31 | Ho'ola Therapeutics Inc. | Combination therapies for the treatment of cancer |
| WO2025019791A1 (en) * | 2023-07-20 | 2025-01-23 | Exelixis, Inc. | Activatable ror binding agents and uses thereof |
| AU2024292307A1 (en) * | 2023-07-20 | 2026-01-29 | Exelixis, Inc. | Tyrosine-protein kinase membrane receptor 1 (ror1) antibody-drug conjugates and uses thereof |
| WO2025019780A1 (en) * | 2023-07-20 | 2025-01-23 | Exelixis, Inc. | Activatable tyrosine-protein kinase membrane receptor (ror) antibody-drug conjugates and uses thereof |
| WO2025132812A1 (en) * | 2023-12-20 | 2025-06-26 | Antalgenics, S.L. | Phospholipase c inhibitor peptides and uses thereof |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7112324B1 (en) | 1998-04-21 | 2006-09-26 | Micromet Ag | CD 19×CD3 specific polypeptides and uses thereof |
| US7985783B2 (en) | 2006-09-21 | 2011-07-26 | The Regents Of The University Of California | Aldehyde tags, uses thereof in site-specific protein modification |
| CA2759733C (en) * | 2009-04-23 | 2019-09-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-human ror1 antibodies |
| US9150647B2 (en) | 2009-12-18 | 2015-10-06 | Kancera Ab | Biological inhibitors of ROR1 capable of inducing cell death |
| US9242014B2 (en) * | 2010-06-15 | 2016-01-26 | The Regents Of The University Of California | Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof |
| EP3828205A1 (en) | 2010-10-01 | 2021-06-02 | Oxford BioTherapeutics Ltd | Anti-ror1 antibodies |
| ES2657970T3 (es) * | 2010-12-01 | 2018-03-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anticuerpos contra ROR1 de conejo/ser humano quiméricos |
| ES2702315T3 (es) * | 2012-08-24 | 2019-02-28 | Univ California | Anticuerpos y vacunas para su uso en tratar cánceres ROR1 e inhibir metástasis |
| EP2789630A1 (en) * | 2013-04-09 | 2014-10-15 | EngMab AG | Bispecific antibodies against CD3e and ROR1 |
| EA035419B9 (ru) | 2014-05-29 | 2020-08-07 | Мэкроудженикс, Инк. | Триспецифичные связывающие молекулы и способы их применения |
| CA2963696A1 (en) * | 2014-10-09 | 2016-04-14 | Engmab Ag | Bispecific antibodies against cd3epsilon and ror1 for use in the treatment of ovarian cancer |
| EP3204415B1 (en) | 2014-10-09 | 2020-06-17 | EngMab Sàrl | Bispecific antibodies against cd3epsilon and ror1 |
| WO2016087650A1 (en) | 2014-12-05 | 2016-06-09 | Merck Patent Gmbh | Domain-exchanged antibody |
| WO2016094873A2 (en) | 2014-12-12 | 2016-06-16 | Emergent Product Development Seattle, Llc | Receptor tyrosine kinase-like orphan receptor 1 binding proteins and related compositions and methods |
| ES2818103T3 (es) | 2015-01-16 | 2021-04-09 | Juno Therapeutics Inc | Anticuerpos y receptores de antígenos quiméricos específicos para ROR1 |
| US11673957B2 (en) * | 2015-03-10 | 2023-06-13 | Eureka Therapeutics, Inc. | Anti-ROR2 antibodies |
| WO2016187220A2 (en) | 2015-05-18 | 2016-11-24 | Five Prime Therapeutics, Inc. | Anti-ror1 antibodies |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| SG11201806121PA (en) * | 2016-01-20 | 2018-08-30 | Scripps Research Inst | Ror2 antibody compositions and related methods |
| TW201734049A (zh) | 2016-01-22 | 2017-10-01 | 健生生物科技公司 | 抗－ｒｏｒ１抗體、ｒｏｒ１ ｘ ｃｄ３雙特異性抗體及使用其之方法 |
| WO2017142928A1 (en) | 2016-02-17 | 2017-08-24 | Macrogenics, Inc. | Ror1-binding molecules, and methods of use thereof |
| CN110177805B (zh) | 2016-10-19 | 2024-04-02 | 英温拉公司 | 抗体构建体 |
| WO2019148445A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
-
2019
- 2019-04-18 SG SG11202010235QA patent/SG11202010235QA/en unknown
- 2019-04-18 US US17/048,549 patent/US12084496B2/en active Active
- 2019-04-18 KR KR1020207032901A patent/KR20200143470A/ko active Pending
- 2019-04-18 WO PCT/US2019/028051 patent/WO2019204564A1/en not_active Ceased
- 2019-04-18 BR BR112020021269-5A patent/BR112020021269A2/pt unknown
- 2019-04-18 EA EA202092202A patent/EA202092202A1/ru unknown
- 2019-04-18 MY MYPI2020005435A patent/MY207121A/en unknown
- 2019-04-18 MX MX2020010881A patent/MX2020010881A/es unknown
- 2019-04-18 CA CA3097704A patent/CA3097704A1/en active Pending
- 2019-04-18 AU AU2019256431A patent/AU2019256431B2/en active Active
- 2019-04-18 IL IL316574A patent/IL316574A/en unknown
- 2019-04-18 CN CN201980040982.8A patent/CN112384533A/zh active Pending
- 2019-04-18 JP JP2020556851A patent/JP2021522162A/ja active Pending
- 2019-04-18 EP EP19789299.5A patent/EP3797122A4/en active Pending
-
2020
- 2020-10-14 MX MX2025001902A patent/MX2025001902A/es unknown
- 2020-10-14 MX MX2025001906A patent/MX2025001906A/es unknown
- 2020-10-14 IL IL278061A patent/IL278061A/en unknown
- 2020-10-14 MX MX2025001900A patent/MX2025001900A/es unknown
- 2020-10-16 PH PH12020551716A patent/PH12020551716A1/en unknown
-
2023
- 2023-10-04 JP JP2023172867A patent/JP2023168551A/ja not_active Withdrawn
-
2024
- 2024-08-12 US US18/801,013 patent/US20240392002A1/en active Pending
-
2025
- 2025-07-11 JP JP2025117193A patent/JP2025137618A/ja active Pending
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