JP2021502984A5 - - Google Patents
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- Publication number
- JP2021502984A5 JP2021502984A5 JP2020526504A JP2020526504A JP2021502984A5 JP 2021502984 A5 JP2021502984 A5 JP 2021502984A5 JP 2020526504 A JP2020526504 A JP 2020526504A JP 2020526504 A JP2020526504 A JP 2020526504A JP 2021502984 A5 JP2021502984 A5 JP 2021502984A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- seq
- activation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025269754A JP2026040534A (ja) | 2017-11-15 | 2025-12-19 | Ｆｘ活性化を促進する第ｘ因子結合剤 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17201762 | 2017-11-15 | ||
| EP17201762.6 | 2017-11-15 | ||
| EP18174634.8 | 2018-05-28 | ||
| EP18174634 | 2018-05-28 | ||
| PCT/EP2018/081296 WO2019096874A1 (en) | 2017-11-15 | 2018-11-15 | Factor x binders enhancing fx activation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025269754A Division JP2026040534A (ja) | 2017-11-15 | 2025-12-19 | Ｆｘ活性化を促進する第ｘ因子結合剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021502984A JP2021502984A (ja) | 2021-02-04 |
| JP2021502984A5 true JP2021502984A5 (https=) | 2021-12-02 |
| JP7841846B2 JP7841846B2 (ja) | 2026-04-07 |
Family
ID=64426877
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526504A Active JP7841846B2 (ja) | 2017-11-15 | 2018-11-15 | Ｆｘ活性化を促進する第ｘ因子結合剤 |
| JP2025269754A Pending JP2026040534A (ja) | 2017-11-15 | 2025-12-19 | Ｆｘ活性化を促進する第ｘ因子結合剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025269754A Pending JP2026040534A (ja) | 2017-11-15 | 2025-12-19 | Ｆｘ活性化を促進する第ｘ因子結合剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11787874B2 (https=) |
| EP (2) | EP4667496A2 (https=) |
| JP (2) | JP7841846B2 (https=) |
| CN (2) | CN118745229A (https=) |
| ES (1) | ES3050257T3 (https=) |
| MA (1) | MA50893A (https=) |
| WO (1) | WO2019096874A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201709970D0 (en) | 2017-06-22 | 2017-08-09 | Kymab Ltd | Bispecific antigen-binding molecules |
| US11787874B2 (en) * | 2017-11-15 | 2023-10-17 | Novo Nordisk A/S | Factor X binders enhancing FX activation |
| PL3723858T3 (pl) | 2018-12-21 | 2022-03-07 | Kymab Limited | Przeciwciało dwuswoiste fixaxfx o wspólnym łańcuchu lekkim |
| WO2021061842A1 (en) | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for single domain antibodies |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| JP2023106635A (ja) | 2020-04-17 | 2023-08-02 | 中外製薬株式会社 | 二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法 |
| EP4314075A4 (en) * | 2021-03-24 | 2025-04-09 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CD3 |
| WO2023111018A1 (en) * | 2021-12-17 | 2023-06-22 | F. Hoffmann-La Roche Ag | Antibodies against coagulation factor x and uses thereof |
| WO2023225035A2 (en) * | 2022-05-16 | 2023-11-23 | Artisan Development Labs, Inc. | Compositions and methods for engineering cells |
| MA71385A (fr) * | 2022-07-08 | 2025-04-30 | Novo Nordisk A/S | Composés isvd hautement puissants capables de remplacer fviii(a) |
| AR129879A1 (es) * | 2022-07-08 | 2024-10-09 | Novo Nordisk As | Compuestos de isvd altamente potentes capaces de sustituir al fviii(a) |
| CN115960227A (zh) * | 2022-11-08 | 2023-04-14 | 河南赛诺特生物技术有限公司 | 一种抗人msh2的单克隆抗体及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| AU7214294A (en) | 1993-07-01 | 1995-01-24 | Dade International Inc. | Process for the preparation of factor x depleted plasma |
| WO2000007626A1 (en) | 1998-08-07 | 2000-02-17 | Smithkline Beecham Corporation | Use of anti-coagulation factor antibodies as long-lasting protective agents |
| US20060073141A1 (en) | 2001-06-28 | 2006-04-06 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| WO2005044858A1 (en) | 2003-11-07 | 2005-05-19 | Ablynx N.V. | Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor |
| CA2505316C (en) * | 2002-11-08 | 2014-08-05 | Ablynx N.V. | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| US7461263B2 (en) | 2003-01-23 | 2008-12-02 | Unspam, Llc. | Method and apparatus for a non-revealing do-not-contact list system |
| JP5490734B2 (ja) | 2003-10-10 | 2014-05-14 | 中外製薬株式会社 | 機能蛋白質を代替する二種特異性抗体 |
| AU2003271174A1 (en) | 2003-10-10 | 2005-04-27 | Chugai Seiyaku Kabushiki Kaisha | Double specific antibodies substituting for functional protein |
| US7563443B2 (en) | 2004-09-17 | 2009-07-21 | Domantis Limited | Monovalent anti-CD40L antibody polypeptides and compositions thereof |
| CA2603264C (en) | 2005-04-08 | 2017-03-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody substituting for function of blood coagulation factor viii |
| EP2057191A1 (en) | 2006-08-18 | 2009-05-13 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
| KR102069498B1 (ko) | 2007-09-28 | 2020-01-23 | 포톨라 파마슈티컬스, 인코포레이티드 | 인자 Ｘａ 저해제에 대한 안티도트 및 그것을 사용하는 방법 |
| PH12016502073B1 (en) | 2010-11-17 | 2024-04-05 | Chugai Pharmaceutical Co Ltd | Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii |
| TWI831106B (zh) | 2014-06-20 | 2024-02-01 | 日商中外製藥股份有限公司 | 用於因第viii凝血因子及/或活化的第viii凝血因子的活性降低或欠缺而發病及/或進展的疾病之預防及/或治療之醫藥組成物 |
| CA2978038A1 (en) | 2015-04-17 | 2016-10-20 | F. Hoffmann-La Roche Ag | Combination therapy with coagulation factors and multispecific antibodies |
| KR102591955B1 (ko) | 2016-07-29 | 2023-10-19 | 추가이 세이야쿠 가부시키가이샤 | 증강된 fviii 보인자 기능 대체 활성을 갖는 이중특이성 항체 |
| RU2766233C2 (ru) | 2016-09-06 | 2022-02-10 | Чугаи Сейяку Кабусики Кайся | Способы применения биспецифического антитела, которое распознает фактор свертывания ix и/или активированный фактор свертывания ix и фактор свертывания x и/или активированный фактор свертывания x |
| US20230192896A1 (en) | 2016-11-23 | 2023-06-22 | Bioverativ Therapeutics Inc. | Bispecific antibodies binding to coagulation factor ix and coagulation factor x |
| US11787874B2 (en) * | 2017-11-15 | 2023-10-17 | Novo Nordisk A/S | Factor X binders enhancing FX activation |
-
2018
- 2018-11-15 US US16/764,124 patent/US11787874B2/en active Active
- 2018-11-15 ES ES18807239T patent/ES3050257T3/es active Active
- 2018-11-15 EP EP25187342.8A patent/EP4667496A2/en active Pending
- 2018-11-15 WO PCT/EP2018/081296 patent/WO2019096874A1/en not_active Ceased
- 2018-11-15 JP JP2020526504A patent/JP7841846B2/ja active Active
- 2018-11-15 CN CN202411097090.0A patent/CN118745229A/zh active Pending
- 2018-11-15 CN CN201880073999.9A patent/CN111386285B/zh active Active
- 2018-11-15 EP EP18807239.1A patent/EP3710486B1/en active Active
- 2018-11-15 MA MA050893A patent/MA50893A/fr unknown
-
2023
- 2023-09-06 US US18/242,868 patent/US20230416404A1/en active Pending
-
2025
- 2025-12-19 JP JP2025269754A patent/JP2026040534A/ja active Pending
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