|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
AU584690B2
(en)
|
1985-03-11 |
1989-06-01 |
Teijin Limited |
E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
US5525491A
(en)
|
1991-02-27 |
1996-06-11 |
Creative Biomolecules, Inc. |
Serine-rich peptide linkers
|
|
ATE414768T1
(de)
|
1991-04-10 |
2008-12-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
MX9204374A
(es)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
US6420140B1
(en)
|
1996-10-11 |
2002-07-16 |
Abgenix, Inc. |
Production of multimeric protein by cell fusion method
|
|
WO1999004705A1
(en)
|
1997-07-25 |
1999-02-04 |
Tsui Ban C H |
Devices, systems and methods for determining proper placement of epidural catheters
|
|
US7112324B1
(en)
|
1998-04-21 |
2006-09-26 |
Micromet Ag |
CD 19×CD3 specific polypeptides and uses thereof
|
|
EP1666058B1
(en)
|
1998-11-25 |
2011-12-28 |
MCW Research Foundation, Incorporated |
Method of diagnosing a Pseudomonas aeruginosa infection
|
|
AU2001297872B2
(en)
|
2000-11-17 |
2006-11-09 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
US7083784B2
(en)
|
2000-12-12 |
2006-08-01 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
|
WO2002064161A2
(en)
*
|
2001-01-26 |
2002-08-22 |
Mcw Research Foundation, Inc. |
Method and compositions for immunization with the pseudomonas v antigen
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
US20020146753A1
(en)
*
|
2001-04-06 |
2002-10-10 |
Henrik Ditzel |
Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease
|
|
US7119172B2
(en)
|
2001-05-21 |
2006-10-10 |
The Brigham And Women's Hospital, Inc. |
P. aeruginosa mucoid exopolysaccharide specific binding peptides
|
|
US20030232387A1
(en)
*
|
2002-06-14 |
2003-12-18 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind alphaE integrin
|
|
NZ612578A
(en)
|
2005-08-19 |
2014-11-28 |
Abbvie Inc |
Dual variable domain immunoglobin and uses thereof
|
|
US20090215992A1
(en)
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US7790862B2
(en)
|
2006-06-13 |
2010-09-07 |
Zymogenetics, Inc. |
IL-17 and IL-23 antagonists and methods of using the same
|
|
JP2008133206A
(ja)
*
|
2006-11-28 |
2008-06-12 |
Yokohama City Univ |
緑膿菌に対して感染防御能を誘導できる医薬組成物
|
|
US7553936B2
(en)
|
2006-12-04 |
2009-06-30 |
The United States of America as represented by Secretary Department of Health and Human Services |
Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions
|
|
EP2102244A2
(en)
|
2006-12-19 |
2009-09-23 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
|
BRPI0819598A2
(pt)
*
|
2007-11-30 |
2017-05-09 |
Kalobios Pharmaceuticals Inc |
anticorpos para o antígeno pcrv da pseudomonas aeruginosa
|
|
EA020544B1
(ru)
*
|
2008-01-10 |
2014-12-30 |
Шионоги Энд Ко., Лтд. |
АНТИТЕЛА ПРОТИВ PcrV
|
|
BRPI0907046A2
(pt)
|
2008-01-18 |
2015-07-28 |
Medimmune Llc |
Anticorpo de cisteína engenheirada, ácido nucleico isolado, vetor, célula hospedeira, conjugado de anticorpo, composição farmacêutica, métodos de detecção de câncer, doenças ou distúrbios autoimunes, inflamatórios ou infecciosos em um indivíduo e de inibição de proliferação de uma célula alvo
|
|
RU2011126338A
(ru)
|
2008-11-28 |
2013-01-10 |
Эбботт Лэборетриз |
Стабильные композиции антител и способы их стабилизации
|
|
JO3672B1
(ar)
*
|
2008-12-15 |
2020-08-27 |
Regeneron Pharma |
أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
|
|
EP2679515B1
(en)
*
|
2008-12-31 |
2014-07-02 |
W.L. Gore & Associates GmbH |
Venting device
|
|
CA2751433A1
(en)
*
|
2009-02-04 |
2010-08-12 |
Kalobios Pharmaceuticals, Inc. |
Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
|
|
SG174225A1
(en)
*
|
2009-03-11 |
2011-10-28 |
Shionogi & Co |
Humanized pcrv antibody having anti-pseudomonal activity
|
|
EP2408475B1
(en)
*
|
2009-03-18 |
2017-11-15 |
Wake Forest University Health Sciences |
Flagellin fusion proteins and use thereof to induce immune responses against pseudomonas aeruginosa
|
|
CA2755336C
(en)
|
2009-03-20 |
2015-07-14 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
EP2417157A1
(en)
|
2009-04-09 |
2012-02-15 |
Kenta Biotech AG |
Human monoclonal antibody specific for lipolysaccarides (lps) of serotype lats 01 of pseudomonas aeruginosa
|
|
EP2711018A1
(en)
|
2009-06-22 |
2014-03-26 |
MedImmune, LLC |
Engineered Fc regions for site-specific conjugation
|
|
WO2011087799A1
(en)
|
2009-12-22 |
2011-07-21 |
Kalobios Pharmaceuticals, Inc. |
A method of treating a staphylococcus infection in a patient having a low-level pathogenic pseudomonas aeruginosa infection
|
|
PT2673373T
(pt)
*
|
2011-02-08 |
2018-12-05 |
Medimmune Llc |
Anticorpos que ligam especificamente a toxina alfa de staphylococcus aureus e métodos de utilização
|
|
WO2012145626A1
(en)
|
2011-04-22 |
2012-10-26 |
Ancora Pharmaceuticals Inc. |
Synthetic oligosaccharides for staphylococcus vaccine
|
|
RU2014100111A
(ru)
|
2011-06-10 |
2015-07-20 |
МЕДИММЬЮН, ЭлЭлСи |
МОЛЕКУЛЫ, СВЯЗЫВАЮЩИЕСЯ С Psl Pseudomonas, И ПУТИ ИХ ПРИМЕНЕНИЯ
|
|
HRP20201370T1
(hr)
*
|
2011-11-07 |
2020-11-27 |
Medimmune Limited |
Kombinacijske terapije koje koriste anti-pseudomonas psl i pcrv vezujuće molekule
|
|
US9580509B2
(en)
*
|
2011-11-07 |
2017-02-28 |
Medimmune, Llc |
Multispecific and multivalent binding proteins and uses thereof
|
|
EP2820043B1
(en)
*
|
2012-03-02 |
2020-01-15 |
Ablynx N.V. |
Biparatopic pseudomonas aeruginosa pcrv binding single variable domain antibodies
|
|
BR112015010125A2
(pt)
*
|
2012-11-06 |
2017-08-22 |
Medimmune Llc |
Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente
|
|
BR112015010240A2
(pt)
*
|
2012-11-06 |
2017-08-22 |
Medimmune Ltd |
Terapias de combinação através do uso de mo-léculas de ligação de psl e de pcrv anti-pseudomonas
|
|
KR20210083389A
(ko)
|
2012-11-06 |
2021-07-06 |
메디뮨 엘엘씨 |
에스.아우레우스 연관 질병의 치료 방법
|
|
EP3001838A4
(en)
|
2013-05-14 |
2017-02-08 |
Medlmmune, LLC |
Synthetic oligosaccharide subunits of the psl exopolysaccharide of pseudomonas aeruginosa and uses therof
|
|
WO2015171504A1
(en)
*
|
2014-05-05 |
2015-11-12 |
Medimmune, Llc |
Multi-specific anti-pseudomonas psl and pcrv binding molecules and uses thereof
|
|
TWI719938B
(zh)
*
|
2014-06-19 |
2021-03-01 |
美商麥迪紐有限責任公司 |
多重細菌感染之治療
|
|
WO2017095744A1
(en)
*
|
2015-11-30 |
2017-06-08 |
Medimmune, Llc |
Method for preventing or treating nosocomial pneumonia
|
|
SG11201809778TA
(en)
*
|
2016-05-05 |
2018-12-28 |
Univ Pennsylvania |
Dna antibody constructs for use against pseudomonas aeruginosa
|
|
EP3983015A1
(en)
*
|
2019-06-11 |
2022-04-20 |
Regeneron Pharmaceuticals, Inc. |
Anti-pcrv antibodies that bind pcrv, compositions comprising anti-pcrv antibodies, and methods of use thereof
|