|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
UA117466C2
(uk)
|
2012-12-13 |
2018-08-10 |
Мерк Шарп Енд Доме Корп. |
СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
TWI715587B
(zh)
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Tigit結合劑和彼之用途
|
|
EP3334757A4
(en)
*
|
2015-08-14 |
2019-04-03 |
Merck Sharp & Dohme Corp. |
ANTI-Tigit ANTIBODY
|
|
TWI781934B
(zh)
|
2016-05-27 |
2022-11-01 |
美商艾吉納斯公司 |
抗-tim-3抗體及其使用方法
|
|
KR102379464B1
(ko)
|
2016-06-20 |
2022-03-29 |
키맵 리미티드 |
항-pd-l1 항체
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
KR20260030924A
(ko)
|
2016-08-09 |
2026-03-06 |
키맵 리미티드 |
항-icos 항체
|
|
SG10201912663YA
(en)
|
2016-10-11 |
2020-03-30 |
Agenus Inc |
Anti-lag-3 antibodies and methods of use thereof
|
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
CN110662552A
(zh)
|
2016-11-30 |
2020-01-07 |
昂科梅德制药有限公司 |
包含tigit结合剂的癌症治疗方法
|
|
EP3589313A4
(en)
*
|
2017-02-28 |
2021-05-19 |
Seagen Inc. |
ANTI-TIGITE ANTIBODY
|
|
RS64576B1
(sr)
|
2017-05-01 |
2023-10-31 |
Agenus Inc |
Anti-tigit antitela i postupci njihove primene
|
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
|
AU2018263868A1
(en)
|
2017-05-02 |
2019-12-12 |
Merck Sharp & Dohme Llc |
Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
|
|
CN110799213A
(zh)
|
2017-06-01 |
2020-02-14 |
康姆普根有限公司 |
三联组合抗体疗法
|
|
WO2018229163A1
(en)
|
2017-06-14 |
2018-12-20 |
King's College London |
Methods of activating v delta 2 negative gamma delta t cells
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
IL272227B2
(en)
*
|
2017-07-27 |
2025-09-01 |
iTeos Belgium SA |
Anti-tigit antibodies
|
|
US11512129B2
(en)
|
2017-09-29 |
2022-11-29 |
Jiangsu Hengrui Medicine Co., Ltd. |
TIGIT antibody, antigen-binding fragment thereof, and medical use thereof
|
|
EP3728314A1
(en)
|
2017-12-19 |
2020-10-28 |
Kymab Limited |
Bispecific antibody for icos and pd-l1
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
TWI816729B
(zh)
|
2017-12-30 |
2023-10-01 |
英屬開曼群島商百濟神州有限公司 |
抗tigit抗體及其作為治療和診斷的用途
|
|
CA3086936C
(en)
|
2018-02-06 |
2022-11-29 |
I-Mab Biopharma Us Limited |
Antibodies to t cell immunoreceptor with ig and itim domains (tigit) and uses thereof
|
|
US20210024873A1
(en)
|
2018-03-27 |
2021-01-28 |
Bristol-Myers Squibb Company |
Real-time monitoring of protein concentration using ultraviolet signal
|
|
KR20210040827A
(ko)
|
2018-07-25 |
2021-04-14 |
이노벤트 바이오로직스 (쑤저우) 컴퍼니, 리미티드 |
항 tigit 항체 및 그 용도
|
|
JP2021534196A
(ja)
*
|
2018-08-23 |
2021-12-09 |
シージェン インコーポレイテッド |
抗tigit抗体
|
|
CN109384846B
(zh)
*
|
2018-09-25 |
2020-03-03 |
合肥瑞达免疫药物研究所有限公司 |
能够结合tigit的抗体或其抗原结合片段及用途
|
|
KR102885113B1
(ko)
|
2018-10-18 |
2025-11-13 |
머크 샤프 앤드 돔 엘엘씨 |
항-rsv 항체의 제제 및 그의 사용 방법
|
|
CN120842406A
(zh)
|
2018-10-31 |
2025-10-28 |
默沙东有限责任公司 |
抗人pd-1抗体晶体及其使用方法
|
|
CN113316458B
(zh)
|
2018-11-07 |
2024-08-02 |
默沙东有限责任公司 |
抗lag3抗体和抗pd-1抗体的共制剂
|
|
CN113614109A
(zh)
|
2018-12-21 |
2021-11-05 |
Ose免疫疗法公司 |
双功能抗pd-1/il-7分子
|
|
SG11202107474RA
(en)
*
|
2019-01-07 |
2021-08-30 |
iTeos Belgium SA |
Anti-tigit antibodies
|
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
|
WO2020172658A1
(en)
|
2019-02-24 |
2020-08-27 |
Bristol-Myers Squibb Company |
Methods of isolating a protein
|
|
CN109734806B
(zh)
*
|
2019-03-15 |
2022-07-01 |
安徽安科生物工程(集团)股份有限公司 |
一种全人源抗huTIGIT单克隆抗体及其应用
|
|
JP7645198B2
(ja)
|
2019-05-23 |
2025-03-13 |
ブリストル-マイヤーズ スクイブ カンパニー |
細胞培養培地をモニターする方法
|
|
CN114269782B
(zh)
*
|
2019-07-15 |
2023-12-29 |
上海君实生物医药科技股份有限公司 |
抗tigit抗体及其应用
|
|
JP7628111B2
(ja)
*
|
2019-09-03 |
2025-02-07 |
バイオ - テラ ソリューションズ、リミテッド |
抗tigit免疫阻害剤及び応用
|
|
AU2020378335A1
(en)
*
|
2019-11-05 |
2022-04-07 |
Merck Patent Gmbh |
Anti-TIGIT antibodies and uses thereof
|
|
BR112022009405A2
(pt)
*
|
2019-11-15 |
2022-08-09 |
Surface Oncology Inc |
Composições e métodos para imunoterapia
|
|
AU2020406083A1
(en)
|
2019-12-17 |
2022-06-16 |
Boehringer Ingelheim International Gmbh |
Bifunctional molecules comprising an IL-7 variant
|
|
WO2021141977A1
(en)
|
2020-01-07 |
2021-07-15 |
Board Of Regents, The University Of Texas System |
Improved human methyl thioadenosine/adenosine depleting enzyme variants for cancer therapy
|
|
AU2021211799A1
(en)
*
|
2020-01-21 |
2022-08-11 |
Innovent Biologics (Suzhou) Co., Ltd. |
Recombinant fully human anti-TIGIT monoclonal antibody preparations, preparation method therefor and use thereof
|
|
KR20220133238A
(ko)
|
2020-01-29 |
2022-10-04 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
Nrg1 융합체가 있는 암의 치료를 위한 포지오티닙의 용도
|
|
US20230112470A1
(en)
|
2020-01-29 |
2023-04-13 |
Board Of Regents, The University Of Texas System |
Use of egfr/her2 tyrosine kinase inhibitors and/or her2/her3 antibodies for the treatment of cancers with nrg1 fusions
|
|
AU2021232041A1
(en)
*
|
2020-03-06 |
2022-09-08 |
Regeneron Pharmaceuticals, Inc. |
Anti-GITR antibodies and uses thereof
|
|
KR20220154140A
(ko)
|
2020-03-13 |
2022-11-21 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Pvrig 결합 단백질 및 이의 의학적 용도
|
|
CA3176497A1
(en)
|
2020-05-07 |
2021-11-11 |
Fatima MECHTA-GRIGORIOU |
Antxr1 as a biomarker of immunosuppressive fibroblast populations and its use for predicting response to immunotherapy
|
|
CN111995681B
(zh)
*
|
2020-05-09 |
2022-03-08 |
华博生物医药技术(上海)有限公司 |
抗tigit的抗体、其制备方法和应用
|
|
CN115916348A
(zh)
|
2020-06-18 |
2023-04-04 |
基因泰克公司 |
使用抗tigit抗体和pd-1轴结合拮抗剂的治疗
|
|
WO2021258337A1
(en)
*
|
2020-06-24 |
2021-12-30 |
Huahui Health Ltd. |
Human monoclonal antibodies against tigit for immune related diseases
|
|
TW202216778A
(zh)
|
2020-07-15 |
2022-05-01 |
美商安進公司 |
Tigit及cd112r阻斷
|
|
WO2022044010A1
(en)
|
2020-08-26 |
2022-03-03 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Anti-t-cell immunoglobulin and itim domain (tigit) antibodies for the treatment of fungal infections
|
|
US20230374064A1
(en)
|
2020-10-05 |
2023-11-23 |
Bristol-Myers Squibb Company |
Methods for concentrating proteins
|
|
EP4238991A4
(en)
*
|
2020-11-23 |
2024-05-15 |
Guangdong Fapon Biopharma Inc. |
ANTI-TIGIT ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF
|
|
WO2022112198A1
(en)
|
2020-11-24 |
2022-06-02 |
Worldwide Innovative Network |
Method to select the optimal immune checkpoint therapies
|
|
KR20220082776A
(ko)
*
|
2020-12-10 |
2022-06-17 |
주식회사 유틸렉스 |
항-tigit 항체 및 이의 용도
|
|
WO2022148781A1
(en)
|
2021-01-05 |
2022-07-14 |
Institut Curie |
Combination of mcoln activators and immune checkpoint inhibitors
|
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
AU2022253351A1
(en)
|
2021-04-09 |
2023-10-12 |
Boehringer Ingelheim International Gmbh |
New scaffold for bifunctional molecules with improved properties
|
|
AR125753A1
(es)
|
2021-05-04 |
2023-08-09 |
Agenus Inc |
Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos
|
|
CN117916263B
(zh)
*
|
2021-05-10 |
2025-04-25 |
美帝马布生物公司 |
抗tigit抗体及其用途
|
|
CN118871463A
(zh)
|
2021-07-28 |
2024-10-29 |
基因泰克公司 |
用于治疗癌症的方法和组合物
|
|
KR20240039006A
(ko)
*
|
2021-07-28 |
2024-03-26 |
엘피사이언스 (쑤저우) 바이오파마, 엘티디. |
신규 항-sirpa 항체
|
|
JP2024535793A
(ja)
|
2021-09-15 |
2024-10-02 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
Pd-1に特異的に結合するタンパク質及びその医薬的使用
|
|
CN117858903A
(zh)
|
2021-09-15 |
2024-04-09 |
江苏恒瑞医药股份有限公司 |
一种含抗pvrig/tigit双特异性抗体的药物组合物
|
|
JP2024536133A
(ja)
|
2021-09-29 |
2024-10-04 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
抗hsp70抗体およびその治療的使用
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
|
CN118591557A
(zh)
*
|
2022-01-24 |
2024-09-03 |
原启生物科技(上海)有限责任公司 |
靶向tigit的抗原结合蛋白及其用途
|
|
JP2025509274A
(ja)
|
2022-03-09 |
2025-04-11 |
ブリストル-マイヤーズ スクイブ カンパニー |
治療用タンパク質の一過性発現
|
|
PE20251671A1
(es)
|
2022-03-15 |
2025-06-30 |
Compugen Ltd |
Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer
|
|
AU2023259126A1
(en)
*
|
2022-04-29 |
2024-10-31 |
Merck Sharp & Dohme Llc |
Stable formulations of anti-ilt4 antibodies or antigen-binding fragments thererof in combination with anti-pd-1 antibodies and methods of use thereof
|
|
EP4537107A2
(en)
|
2022-06-07 |
2025-04-16 |
Genentech, Inc. |
Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody
|
|
WO2024003360A1
(en)
|
2022-07-01 |
2024-01-04 |
Institut Curie |
Biomarkers and uses thereof for the treatment of neuroblastoma
|
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
|
WO2024041639A1
(en)
*
|
2022-08-26 |
2024-02-29 |
Nanjing Legend Biotech Co., Ltd. |
Antibodies targeting tigit and uses thereof
|
|
CN120693178A
(zh)
|
2023-03-15 |
2025-09-23 |
上海迈晋生物医药科技有限公司 |
一种含pd-1/pvrig/tigit结合蛋白的药物组合物及其医药用途
|
|
CN121358499A
(zh)
|
2023-03-30 |
2026-01-16 |
Ose免疫疗法 |
靶向活化的免疫细胞以表达免疫细胞增强分子的基于脂质的纳米粒及其用途
|
|
AU2024254671A1
(en)
|
2023-03-30 |
2025-10-02 |
Ose Immunotherapeutics |
Method of synthesis of targeted lipid nanoparticle and uses thereof
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Il—18bp拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025068461A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025068452A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025132831A1
(en)
|
2023-12-19 |
2025-06-26 |
Universite D'aix-Marseille |
N-heteroaryl derivatives and uses thereof for treating cancer
|
|
WO2025242835A1
(en)
|
2024-05-22 |
2025-11-27 |
Ose Immunotherapeutics |
Molecules comprising masking linkers and uses thereof for the treatment of cancer
|
|
WO2025242836A1
(en)
|
2024-05-22 |
2025-11-27 |
Ose Immunotherapeutics |
Molecules comprising masking linkers and uses thereof for the treatment of auto-immune or inflammatory diseases and disorders
|
|
WO2025262250A1
(en)
|
2024-06-20 |
2025-12-26 |
Negio Therapeutics |
Guanfacine derivatives and their uses
|
|
WO2026068705A1
(en)
|
2024-09-26 |
2026-04-02 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof
|