JP2017534572A5 - - Google Patents
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- JP2017534572A5 JP2017534572A5 JP2017512313A JP2017512313A JP2017534572A5 JP 2017534572 A5 JP2017534572 A5 JP 2017534572A5 JP 2017512313 A JP2017512313 A JP 2017512313A JP 2017512313 A JP2017512313 A JP 2017512313A JP 2017534572 A5 JP2017534572 A5 JP 2017534572A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- optionally substituted
- group
- independently
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020097823A JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462046450P | 2014-09-05 | 2014-09-05 | |
| US62/046,450 | 2014-09-05 | ||
| PCT/US2015/048640 WO2016037106A1 (en) | 2014-09-05 | 2015-09-04 | CaMKII INHIBITORS AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097823A Division JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534572A JP2017534572A (ja) | 2017-11-24 |
| JP2017534572A5 true JP2017534572A5 (enExample) | 2018-10-11 |
| JP6782227B2 JP6782227B2 (ja) | 2020-11-11 |
Family
ID=54150675
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512313A Expired - Fee Related JP6782227B2 (ja) | 2014-09-05 | 2015-09-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
| JP2020097823A Expired - Fee Related JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097823A Expired - Fee Related JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10759792B2 (enExample) |
| EP (1) | EP3189052B1 (enExample) |
| JP (2) | JP6782227B2 (enExample) |
| CN (1) | CN107074856A (enExample) |
| AU (2) | AU2015311730A1 (enExample) |
| CA (1) | CA2960101C (enExample) |
| WO (1) | WO2016037106A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR110252A1 (es) | 2016-11-30 | 2019-03-13 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como inhibidores de la quinasa cam |
| WO2019049148A1 (en) * | 2017-09-10 | 2019-03-14 | Carmel Haifa University Economic Corporation Ltd. | METHOD OF TREATING DEPRESSION AND MAJOR DEPRESSIVE DISORDER |
| CN108218862B (zh) * | 2018-02-07 | 2020-06-23 | 贵州医科大学 | α-卡波林类衍生物在制备抗心肌缺氧复氧损伤药物中的应用 |
| WO2019165067A1 (en) | 2018-02-21 | 2019-08-29 | Bristol-Myers Squibb Company | Camk2d antisense oligonucleotides and uses thereof |
| CN108904532B (zh) * | 2018-08-20 | 2021-07-27 | 上海市第一人民医院 | 一种富勒烯C60纳米晶体联合CaMKII抑制剂的组合物的应用 |
| EP3887371B1 (en) * | 2018-11-27 | 2023-02-22 | F. Hoffmann-La Roche AG | Aryl compounds for the treatment and prophylaxis of bacterial infection |
| JP7824282B2 (ja) * | 2020-09-28 | 2026-03-04 | カーデュリオン・ファーマシューティカルズ・インコーポレイテッド | 縮合ヘテロアリール化合物およびＣａＭＫＩＩ阻害剤としてのその使用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1913124A (en) * | 1932-01-02 | 1933-06-06 | American Sundries Co Inc | Vaporizer |
| US2690441A (en) * | 1953-06-11 | 1954-09-28 | Searle & Co | 3-carboline derivatives |
| GB1268773A (en) * | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
| BE758991A (fr) * | 1969-11-18 | 1971-05-17 | Reeves Bros Inc | Procede de reticulation hydrodynamique d'une mousse de polyurethanne |
| PL80610B1 (enExample) * | 1970-03-12 | 1975-08-30 | ||
| GB8600651D0 (en) * | 1986-01-11 | 1986-02-19 | Beecham Group Plc | Compounds |
| DE4435477A1 (de) * | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
| JP2001509808A (ja) | 1997-01-31 | 2001-07-24 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 多機能性カルシウム／カルモジュリン−依存性プロテインキナーゼの阻害による不整脈の処置 |
| MXPA04003040A (es) | 2001-10-01 | 2004-07-15 | Vanderbil University | Uso de inhibidores de calmodulin quinasa ii para tratar la disfuncion miocardica en la enfermedad de corazon estructural. |
| AU2003300522A1 (en) | 2002-12-27 | 2004-07-22 | Bayer Healthcare Ag | 4-phenyl-pyrimido (4,5-b) indole derivatives |
| US20060057639A1 (en) | 2004-06-16 | 2006-03-16 | Pitt Geoffrey S | CaMKII/calcium channel phosphorylation-related compositions and methods |
| FR2876377B1 (fr) * | 2004-10-11 | 2007-03-16 | Univ Claude Bernard Lyon | Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes |
| US20080255121A1 (en) | 2004-11-02 | 2008-10-16 | Dainippon Sumitomo Pharma Co., Ltd. | Combination Drug for Treating Autoimmune Disease |
| AU2006247322A1 (en) | 2005-05-16 | 2006-11-23 | Irm Llc | Pyrrolopyridine derivatives as protein kinase inhibitors |
| JP2008545660A (ja) | 2005-05-20 | 2008-12-18 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼ阻害剤として有用なピロロピリジン化合物 |
| US20070004684A1 (en) * | 2005-06-09 | 2007-01-04 | Boehringer Ingelheim International Gmbh | Alpha-Carbolines as CDK-1 inhibitors |
| WO2007005831A2 (en) | 2005-07-01 | 2007-01-11 | Texas A & M University System | Zinc oxide polymer nanocomposites and methods of producing zinc oxide polymer nanocomposites |
| WO2007084667A2 (en) | 2006-01-19 | 2007-07-26 | Osi Pharmaceutical, Inc. | Fused heterobicyclic kinase inhibitors |
| TW200908968A (en) | 2007-05-29 | 2009-03-01 | Sgx Pharmaceuticals Inc | Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators |
| EP2599763A1 (en) * | 2008-02-14 | 2013-06-05 | Siemens Molecular Imaging, Inc. | Novel imaging agents for detecting neurological dysfunction |
| MX2011000837A (es) | 2008-07-23 | 2011-04-05 | Vertex Pharma | Inhibidores de pirazolpiridina cinasa triciclica. |
| WO2010017048A1 (en) | 2008-08-06 | 2010-02-11 | Merck & Co., Inc. | Substituted dihydroisoquinolinone and isoquinolinedione derivatives as calcium channel blockers |
| EP2161271A1 (en) | 2008-09-08 | 2010-03-10 | Università Degli Studi Di Milano - Bicocca | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl |
| AR073923A1 (es) | 2008-10-31 | 2010-12-09 | Medivation Technologies Inc | Pirido( 4,3-b) indoles que contienen restos rigidos |
| JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Ｅｇ５阻害剤 |
| US8440656B2 (en) | 2009-06-22 | 2013-05-14 | University Of Iowa Research Foundation | Methods of treating pulmonary diseases and disorders by modulating calcium/calmodulin dependent protein kinase II activity |
| US8685969B2 (en) | 2010-06-16 | 2014-04-01 | Bristol-Myers Squibb Company | Carboline carboxamide compounds useful as kinase inhibitors |
| EP2758376A4 (en) * | 2011-09-19 | 2015-04-29 | Vitas Pharma Res Private Ltd | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FATTY ACID BIOSYNTHESIS FOR BACTERIAL INFECTIONS |
| JP6535430B2 (ja) * | 2012-09-28 | 2019-06-26 | イグニタ、インク． | 非定型プロテインキナーゼｃのアザキナゾリン阻害薬 |
| CN105517549B (zh) | 2013-03-06 | 2018-11-23 | 阿略斯泰罗斯医疗公司 | CaMKII抑制剂和其用途 |
-
2015
- 2015-09-04 CA CA2960101A patent/CA2960101C/en active Active
- 2015-09-04 WO PCT/US2015/048640 patent/WO2016037106A1/en not_active Ceased
- 2015-09-04 AU AU2015311730A patent/AU2015311730A1/en not_active Abandoned
- 2015-09-04 EP EP15766981.3A patent/EP3189052B1/en active Active
- 2015-09-04 US US15/506,501 patent/US10759792B2/en active Active
- 2015-09-04 JP JP2017512313A patent/JP6782227B2/ja not_active Expired - Fee Related
- 2015-09-04 CN CN201580058739.0A patent/CN107074856A/zh active Pending
-
2020
- 2020-06-04 JP JP2020097823A patent/JP6918378B2/ja not_active Expired - Fee Related
- 2020-06-12 AU AU2020203927A patent/AU2020203927B9/en not_active Ceased
- 2020-08-24 US US17/000,644 patent/US11325908B2/en active Active
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