JP2017534572A5 - - Google Patents
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- JP2017534572A5 JP2017534572A5 JP2017512313A JP2017512313A JP2017534572A5 JP 2017534572 A5 JP2017534572 A5 JP 2017534572A5 JP 2017512313 A JP2017512313 A JP 2017512313A JP 2017512313 A JP2017512313 A JP 2017512313A JP 2017534572 A5 JP2017534572 A5 JP 2017534572A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- optionally substituted
- group
- independently
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020097823A JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462046450P | 2014-09-05 | 2014-09-05 | |
| US62/046,450 | 2014-09-05 | ||
| PCT/US2015/048640 WO2016037106A1 (en) | 2014-09-05 | 2015-09-04 | CaMKII INHIBITORS AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097823A Division JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534572A JP2017534572A (ja) | 2017-11-24 |
| JP2017534572A5 true JP2017534572A5 (enExample) | 2018-10-11 |
| JP6782227B2 JP6782227B2 (ja) | 2020-11-11 |
Family
ID=54150675
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512313A Active JP6782227B2 (ja) | 2014-09-05 | 2015-09-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
| JP2020097823A Expired - Fee Related JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020097823A Expired - Fee Related JP6918378B2 (ja) | 2014-09-05 | 2020-06-04 | ＣａＭＫＩＩ阻害剤及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10759792B2 (enExample) |
| EP (1) | EP3189052B1 (enExample) |
| JP (2) | JP6782227B2 (enExample) |
| CN (1) | CN107074856A (enExample) |
| AU (2) | AU2015311730A1 (enExample) |
| CA (1) | CA2960101C (enExample) |
| WO (1) | WO2016037106A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR110252A1 (es) | 2016-11-30 | 2019-03-13 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como inhibidores de la quinasa cam |
| WO2019049148A1 (en) * | 2017-09-10 | 2019-03-14 | Carmel Haifa University Economic Corporation Ltd. | METHOD OF TREATING DEPRESSION AND MAJOR DEPRESSIVE DISORDER |
| CN108218862B (zh) * | 2018-02-07 | 2020-06-23 | 贵州医科大学 | α-卡波林类衍生物在制备抗心肌缺氧复氧损伤药物中的应用 |
| JP7500426B2 (ja) | 2018-02-21 | 2024-06-17 | ブリストル－マイヤーズ スクイブ カンパニー | Ｃａｍｋ２ｄアンチセンスオリゴヌクレオチドおよびその使用 |
| CN108904532B (zh) * | 2018-08-20 | 2021-07-27 | 上海市第一人民医院 | 一种富勒烯C60纳米晶体联合CaMKII抑制剂的组合物的应用 |
| EP3887371B1 (en) * | 2018-11-27 | 2023-02-22 | F. Hoffmann-La Roche AG | Aryl compounds for the treatment and prophylaxis of bacterial infection |
| MX2023003610A (es) * | 2020-09-28 | 2023-07-20 | Cardurion Pharmaceuticals Inc | Compuestos de heteroarilo fusionado y su uso como inhibidores de proteína cinasa ii dependiente de calcio/calmodulina (camkii). |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1913124A (en) * | 1932-01-02 | 1933-06-06 | American Sundries Co Inc | Vaporizer |
| US2690441A (en) * | 1953-06-11 | 1954-09-28 | Searle & Co | 3-carboline derivatives |
| GB1268773A (en) * | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
| BE758991A (fr) * | 1969-11-18 | 1971-05-17 | Reeves Bros Inc | Procede de reticulation hydrodynamique d'une mousse de polyurethanne |
| PL80610B1 (enExample) * | 1970-03-12 | 1975-08-30 | ||
| GB8600651D0 (en) * | 1986-01-11 | 1986-02-19 | Beecham Group Plc | Compounds |
| DE4435477A1 (de) * | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
| ATE218854T1 (de) | 1997-01-31 | 2002-06-15 | Univ Leland Stanford Junior | Behandlung von herzrythmusstörungen durch hemmung einer multifunktionalen calcium/calmodulin- abhängigen protein kinase |
| IL161231A0 (en) | 2001-10-01 | 2004-09-27 | Univ Vanderbilt | Use of calmodulin kinase ii inhibitors to treat myocardial dysfunction in structural heart disease |
| WO2004058764A1 (en) | 2002-12-27 | 2004-07-15 | Bayer Healthcare Ag | 4-phenyl-pyrimido [4,5-b] indole derivatives |
| WO2006007422A2 (en) | 2004-06-16 | 2006-01-19 | The Trustees Fo Columbia University In The City Of New York | CaMKII/CALCIUM CHANNEL PHOSPHORYLATION-RELATED COMPOSITIONS AND METHODS |
| FR2876377B1 (fr) * | 2004-10-11 | 2007-03-16 | Univ Claude Bernard Lyon | Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes |
| WO2006049215A1 (ja) | 2004-11-02 | 2006-05-11 | Dainippon Sumitomo Pharma Co., Ltd. | 自己免疫疾患を治療するための併用薬 |
| CA2608333A1 (en) | 2005-05-16 | 2006-11-23 | Irm Llc | Pyrrolopyridine derivatives as protein kinase inhibitors |
| EP2354139A1 (en) | 2005-05-20 | 2011-08-10 | Vertex Pharmaceuticals Incorporated | Pyrrolopyridines useful as inhibitors of protein kinase |
| JP2008542433A (ja) * | 2005-06-09 | 2008-11-27 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＣＤＫ−１インヒビターとしてのα−カルボリン |
| WO2007005831A2 (en) | 2005-07-01 | 2007-01-11 | Texas A & M University System | Zinc oxide polymer nanocomposites and methods of producing zinc oxide polymer nanocomposites |
| US20070208053A1 (en) | 2006-01-19 | 2007-09-06 | Arnold Lee D | Fused heterobicyclic kinase inhibitors |
| CL2008001540A1 (es) | 2007-05-29 | 2009-05-22 | Sgx Pharmaceuticals Inc | Compuestos derivados de pirrolopiridinas y pirazolopiridinas; composicion farmaceutica; y uso en el tratamiento del cancer. |
| KR20100135235A (ko) * | 2008-02-14 | 2010-12-24 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | 신경학적 기능이상을 검출하기 위한 조영제 |
| MX2011000837A (es) | 2008-07-23 | 2011-04-05 | Vertex Pharma | Inhibidores de pirazolpiridina cinasa triciclica. |
| US20110136842A1 (en) | 2008-08-06 | 2011-06-09 | Duffy Joseph L | Substituted Dihydroisoquinolinone and Isoquinolinedione Derivatives as Calcium Channel Blockers |
| EP2161271A1 (en) | 2008-09-08 | 2010-03-10 | Università Degli Studi Di Milano - Bicocca | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl |
| WO2010051501A1 (en) | 2008-10-31 | 2010-05-06 | Medivation Technologies, Inc. | Pyrido (4,3-b) indoles containing rigid moieties |
| JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Ｅｇ５阻害剤 |
| US8440656B2 (en) | 2009-06-22 | 2013-05-14 | University Of Iowa Research Foundation | Methods of treating pulmonary diseases and disorders by modulating calcium/calmodulin dependent protein kinase II activity |
| US8685969B2 (en) | 2010-06-16 | 2014-04-01 | Bristol-Myers Squibb Company | Carboline carboxamide compounds useful as kinase inhibitors |
| EP3330269B1 (en) * | 2011-09-19 | 2023-06-07 | Kumar, Ajay | Heterocyclic compounds as inhibitors of fatty acid biosynthesis for bacterial infections |
| AU2013323360B2 (en) * | 2012-09-28 | 2017-09-07 | Cancer Research Technology Limited | Azaquinazoline inhibitors of atypical protein kinase C |
| AU2014225889B2 (en) | 2013-03-06 | 2018-12-06 | The Johns Hopkins University | CaMKII inhibitors and uses thereof |
-
2015
- 2015-09-04 US US15/506,501 patent/US10759792B2/en active Active
- 2015-09-04 JP JP2017512313A patent/JP6782227B2/ja active Active
- 2015-09-04 EP EP15766981.3A patent/EP3189052B1/en active Active
- 2015-09-04 WO PCT/US2015/048640 patent/WO2016037106A1/en not_active Ceased
- 2015-09-04 CA CA2960101A patent/CA2960101C/en active Active
- 2015-09-04 AU AU2015311730A patent/AU2015311730A1/en not_active Abandoned
- 2015-09-04 CN CN201580058739.0A patent/CN107074856A/zh active Pending
-
2020
- 2020-06-04 JP JP2020097823A patent/JP6918378B2/ja not_active Expired - Fee Related
- 2020-06-12 AU AU2020203927A patent/AU2020203927B9/en not_active Ceased
- 2020-08-24 US US17/000,644 patent/US11325908B2/en active Active
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