JP2017533700A5 - - Google Patents
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- JP2017533700A5 JP2017533700A5 JP2017520352A JP2017520352A JP2017533700A5 JP 2017533700 A5 JP2017533700 A5 JP 2017533700A5 JP 2017520352 A JP2017520352 A JP 2017520352A JP 2017520352 A JP2017520352 A JP 2017520352A JP 2017533700 A5 JP2017533700 A5 JP 2017533700A5
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- insecticidal protein
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| US10572836B2 (en) | 2015-10-15 | 2020-02-25 | International Business Machines Corporation | Automatic time interval metadata determination for business intelligence and predictive analytics |
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| US11345925B2 (en) | 2016-10-21 | 2022-05-31 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
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| CA3044425A1 (en) | 2017-01-04 | 2018-07-12 | Syngenta Participations Ag | Compositions and methods for controlling plant pests |
| US10703782B2 (en) | 2017-01-12 | 2020-07-07 | Monsanto Technology Llc | Pesticidal toxin proteins active against lepidopteran insects |
| US20200165626A1 (en) | 2017-10-13 | 2020-05-28 | Pioneer Hi-Bred International, Inc. | Virus-induced gene silencing technology for insect control in maize |
| CN108148841B (zh) * | 2017-12-14 | 2020-12-29 | 云南大学 | 氨基酸序列在用于使昆虫Dip3蛋白失活中的应用 |
| EP4122947A1 (en) * | 2017-12-19 | 2023-01-25 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides and uses thereof |
| AU2019234562B2 (en) * | 2018-03-14 | 2024-08-01 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| CA3092078A1 (en) | 2018-03-14 | 2019-09-19 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| CR20210046A (es) * | 2018-07-30 | 2021-06-10 | Monsanto Technology Llc | Evento transgénico de maíz mon 95379 y métodos para su detección y usos |
| CN109198845A (zh) * | 2018-08-21 | 2019-01-15 | 广州杰赛科技股份有限公司 | 全自主甲面彩绘装置、方法、设备及存储介质 |
| WO2020046701A1 (en) | 2018-08-29 | 2020-03-05 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CN113179822A (zh) * | 2020-01-14 | 2021-07-30 | 先正达生物科技(中国)有限公司 | 棉铃虫的控制 |
| CN113179823B (zh) * | 2020-01-14 | 2025-10-28 | 先正达生物科技(中国)有限公司 | 小地老虎的控制 |
| CN111100208A (zh) * | 2020-01-16 | 2020-05-05 | 黑龙江大鹏农业有限公司 | 一种人工合成的抗虫蛋白mCry1Ia2及其制备方法和应用 |
| WO2022125639A1 (en) | 2020-12-08 | 2022-06-16 | Monsanto Technology Llc | Modified plant-associated bacteria and methods of their use |
| CN116670155A (zh) | 2020-12-21 | 2023-08-29 | 孟山都技术公司 | 新型昆虫抑制性蛋白质 |
| UY39585A (es) | 2020-12-23 | 2022-07-29 | Monsanto Technology Llc | Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas |
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| CN116848250A (zh) | 2020-12-31 | 2023-10-03 | 孟山都技术公司 | 新型昆虫抑制蛋白 |
| EP4314289A1 (en) | 2021-03-26 | 2024-02-07 | Flagship Pioneering Innovations VII, LLC | Production of circular polyribonucleotides in a prokaryotic system |
| WO2022204460A1 (en) | 2021-03-26 | 2022-09-29 | Flagship Pioneering Innovations Vii, Llc | Compositions and methods for producing circular polyribonucleotides |
| EP4314281A1 (en) | 2021-03-26 | 2024-02-07 | Flagship Pioneering Innovations VII, LLC | Production of circular polyribonucleotides in a eukaryotic system |
| AR125862A1 (es) * | 2021-05-21 | 2023-08-23 | Syngenta Crop Protection Ag | Composiciones y métodos para controlar insectos |
| WO2023283103A1 (en) | 2021-07-08 | 2023-01-12 | Monsanto Technology Llc | Novel insect inhibitory proteins |
| CN114134171B (zh) * | 2021-10-29 | 2023-09-15 | 隆平生物技术(海南)有限公司 | 一种抑制或杀灭东方黏虫的方法及其应用 |
| WO2023077118A1 (en) | 2021-11-01 | 2023-05-04 | Flagship Pioneering Innovations Vii, Llc | Polynucleotides for modifying organisms |
| CN114507673A (zh) * | 2022-01-20 | 2022-05-17 | 隆平生物技术(海南)有限公司 | 一种抑制或杀灭小地老虎的方法及应用 |
| KR20240135651A (ko) | 2022-01-20 | 2024-09-11 | 플래그쉽 파이어니어링 이노베이션스 Vii, 엘엘씨 | 유기체를 변형하기 위한 폴리뉴클레오티드 |
| CN116063431B (zh) * | 2022-09-19 | 2023-11-10 | 隆平生物技术(海南)有限公司 | 一种植物抗虫蛋白质及其应用 |
| CN120476134A (zh) * | 2022-11-04 | 2025-08-12 | 巴西农业研究公司-恩布拉帕 | 截短的嵌合杀虫蛋白 |
| EP4705474A2 (en) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Artificial tymovirales satellite rnas |
| CN121712898A (zh) | 2023-05-03 | 2026-03-20 | 旗舰创业创新第七有限责任公司 | 用于植物的内源核糖核酸病毒卫星rna扩增系统 |
| AR132591A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de secoviridae artificiales |
| AR132592A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de ghabrivirales artificiales |
| EP4705478A1 (en) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Artificial martellivirales satellite rnas |
| EP4705476A1 (en) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Artificial amalgavirus satellite rnas |
| CN121712897A (zh) | 2023-05-03 | 2026-03-20 | 旗舰创业创新第七有限责任公司 | 用于植物的分体病毒卫星rna扩增系统 |
| EP4705470A1 (en) | 2023-05-03 | 2026-03-11 | Flagship Pioneering Innovations VII, LLC | Artificial tombusviridae satellite rnas |
| AR132589A1 (es) | 2023-05-03 | 2025-07-16 | Flagship Pioneering Innovations Vii Llc | Arn satélite de solemoviridae artificiales |
| CN117144054B (zh) * | 2023-10-27 | 2024-06-11 | 莱肯生物科技(海南)有限公司 | 一种核酸检测方法及其应用 |
| CN120058883A (zh) * | 2023-11-28 | 2025-05-30 | 青岛清原种子科学有限公司 | 一种突变杀虫蛋白Vip3Aa及其应用 |
| WO2025195492A1 (zh) * | 2024-03-22 | 2025-09-25 | 莱肯生物科技(海南)有限公司 | 一种杀虫蛋白及其应用 |
| CN121249682B (zh) * | 2025-12-08 | 2026-03-17 | 中国农业科学院都市农业研究所 | 一种胃毒杀虫活性多肽及其制备方法与应用 |
Family Cites Families (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3587548T2 (de) | 1984-12-28 | 1993-12-23 | Bayer Ag | Rekombinante DNA, die in pflanzliche Zellen eingebracht werden kann. |
| CA1313830C (en) | 1985-08-07 | 1993-02-23 | Dilip Maganlal Shah | Glyphosate-resistant plants |
| US5312910A (en) | 1987-05-26 | 1994-05-17 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase |
| AU638438B2 (en) | 1989-02-24 | 1993-07-01 | Monsanto Technology Llc | Synthetic plant genes and method for preparation |
| PL295547A1 (https=) | 1990-04-26 | 1992-10-05 | Plant Genetic Systems Nv | |
| US5633435A (en) | 1990-08-31 | 1997-05-27 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases |
| FR2673643B1 (fr) | 1991-03-05 | 1993-05-21 | Rhone Poulenc Agrochimie | Peptide de transit pour l'insertion d'un gene etranger dans un gene vegetal et plantes transformees en utilisant ce peptide. |
| US5723758A (en) * | 1991-09-13 | 1998-03-03 | Mycogen Corporation | Bacillus thuringiensis genes encoding lepidopteran-active toxins |
| US5262324A (en) | 1991-11-06 | 1993-11-16 | Mycogen Corporation | Coleopteran-active Bacillus thuringiensis isolates and genes encoding coleopteran-active toxins |
| US5273746A (en) | 1992-01-29 | 1993-12-28 | Mycogen Corporation | Bacillus thuringiensis isolates active against phthiraptera pests |
| US5322687A (en) | 1993-07-29 | 1994-06-21 | Ecogen Inc. | Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects |
| GB9318207D0 (en) | 1993-09-02 | 1993-10-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5508264A (en) * | 1994-12-06 | 1996-04-16 | Mycogen Corporation | Pesticidal compositions |
| US6063756A (en) * | 1996-09-24 | 2000-05-16 | Monsanto Company | Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor |
| US6713063B1 (en) | 1996-11-20 | 2004-03-30 | Monsanto Technology, Llc | Broad-spectrum δ-endotoxins |
| AP9901541A0 (en) | 1996-11-20 | 1999-06-30 | Ecogen Inc | Broad-spectrum delta-endotoxins. |
| US6017534A (en) | 1996-11-20 | 2000-01-25 | Ecogen, Inc. | Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity |
| US5942664A (en) | 1996-11-27 | 1999-08-24 | Ecogen, Inc. | Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants |
| US6218188B1 (en) * | 1997-11-12 | 2001-04-17 | Mycogen Corporation | Plant-optimized genes encoding pesticidal toxins |
| US6489542B1 (en) | 1998-11-04 | 2002-12-03 | Monsanto Technology Llc | Methods for transforming plants to express Cry2Ab δ-endotoxins targeted to the plastids |
| US6283613B1 (en) | 1999-07-29 | 2001-09-04 | Cooper Technologies Company | LED traffic light with individual LED reflectors |
| AU6702300A (en) | 1999-08-19 | 2001-03-19 | Syngenta Participations Ag | Hybrid insecticidal toxins and nucleic acid sequences coding therefor |
| US6501009B1 (en) | 1999-08-19 | 2002-12-31 | Monsanto Technology Llc | Expression of Cry3B insecticidal protein in plants |
| US6593293B1 (en) * | 1999-09-15 | 2003-07-15 | Monsanto Technology, Llc | Lepidopteran-active Bacillus thuringiensis δ-endotoxin compositions and methods of use |
| WO2002014517A1 (en) * | 2000-08-11 | 2002-02-21 | Monsanto Technology Llc | BROAD-SPECTRUM δ-ENDOTOXINS |
| AU2001285900B2 (en) * | 2000-08-25 | 2005-02-17 | Syngenta Participations Ag | Novel insecticidal toxins derived from bacillus thuringiensis insecticidal crystal proteins |
| AR035799A1 (es) * | 2001-03-30 | 2004-07-14 | Syngenta Participations Ag | Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos. |
| CN101385467B (zh) * | 2001-03-30 | 2014-11-05 | 辛根塔参与股份公司 | 新的杀虫毒素 |
| ES2203310B1 (es) | 2001-12-28 | 2005-06-01 | Universidad Publica De Navarra | Nueva cepa de bacillus thuringiensis con multiples genes cry toxica contra lepidopteros plaga. |
| CN101508725B (zh) * | 2002-03-22 | 2013-08-07 | 拜尔作物科学公司 | 新的苏云金芽孢杆菌杀昆虫蛋白质 |
| WO2004020636A1 (en) * | 2002-08-29 | 2004-03-11 | Monsanto Technology, Llc | Nucleotide sequences encoding cry1bb proteins for enhanced expression in plants |
| AU2005244258B2 (en) | 2004-04-09 | 2010-07-01 | Monsanto Technology Llc | Compositions and methods for control of insect infestations in plants |
| ATE482281T1 (de) | 2004-06-09 | 2010-10-15 | Pioneer Hi Bred Int | Plastiden transit peptide |
| NZ562795A (en) | 2005-04-01 | 2009-07-31 | Athenix Corp | AXMI-036, a delta-endotoxin gene and methods for its use |
| EA015908B1 (ru) * | 2005-08-31 | 2011-12-30 | Монсанто Текнолоджи, Ллс | Инсектицидный белок в.thuringiensis cry1a.105, кодирующий его полинуклеотид и их применение |
| AU2012200658B2 (en) | 2005-08-31 | 2014-01-23 | Monsanto Technology Llc | "Controlling insect infestation" |
| AR062019A1 (es) | 2006-07-21 | 2008-08-10 | Pioneer Hi Bred Int | Gen de bacillus thuringiensis con actividad contra lepidopteros |
| US8148077B2 (en) | 2006-07-21 | 2012-04-03 | Pioneer Hi-Bred International, Inc. | Method for identifying novel genes |
| EA200970559A1 (ru) | 2006-12-08 | 2009-12-30 | Пайонир Хай-Бред Интернэшнл, Инк. | Новые кристаллические полипептиды из bacillus thuringiensis, кодирующие их полинуклеотиды и композиции этих соединений |
| EP2450448B1 (en) | 2007-03-09 | 2014-09-17 | Monsanto Technology LLC | Methods for plant transformation using spectinomycin selection |
| ES2601577T3 (es) | 2007-03-28 | 2017-02-15 | Syngenta Participations Ag | Proteínas insecticidas |
| US8609936B2 (en) * | 2007-04-27 | 2013-12-17 | Monsanto Technology Llc | Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis |
| AU2008248360B2 (en) | 2007-05-08 | 2013-05-23 | Monsanto Technology Llc | Methods for inducing cotton embryogenic callus |
| US7772465B2 (en) | 2007-06-26 | 2010-08-10 | Pioneer Hi-Bred International, Inc. | Bacillus thuringiensis gene with lepidopteran activity |
| BRPI0815980A2 (pt) | 2007-08-31 | 2015-06-16 | Monsanto Technology Llc | Métodos e aparelhos para isolar substancialmente tecidos de planta |
| US8283524B2 (en) | 2008-05-15 | 2012-10-09 | Pioneer Hi-Bred International, Inc | Bacillus thuringiensis gene with lepidopteran activity |
| US8129594B2 (en) * | 2008-06-11 | 2012-03-06 | Pioneer Hi-Bred International, Inc. | Bacillus thuringiensis gene with lepidopteran activity |
| WO2009151748A1 (en) | 2008-06-11 | 2009-12-17 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with lepidopteran activity |
| BRPI0914780B8 (pt) | 2008-06-25 | 2022-07-05 | Athenix Corp | Molécula de ácido nucleico isolada, vetor, célula hospedeira, composição, e métodos para o controle de uma população de pragas, matar uma praga proteção de uma planta de uma praga e produção de um polipeptídeo com atividade pesticida |
| JP2011526791A (ja) | 2008-07-02 | 2011-10-20 | アテニックス・コーポレーション | Bacillusthuringiensis由来のVip3A殺昆虫性タンパク質であるAXMI−115、AXMI−113、AXMI−005、AXMI−163およびAXMI−184並びにその使用法 |
| US8445749B2 (en) | 2008-09-19 | 2013-05-21 | Pioneer Hi Bred International Inc | Bacillus thuringiensis gene with lepidopteran activity |
| US20100077507A1 (en) | 2008-09-22 | 2010-03-25 | Pioneer Hi-Bred International, Inc. | Novel Bacillus Thuringiensis Gene with Lepidopteran Activity |
| EP2361307B1 (en) | 2008-12-22 | 2014-09-24 | Athenix Corporation | Pesticidal genes from Brevibacillus and methods for their use |
| EP2379724B1 (en) | 2008-12-23 | 2015-01-21 | Athenix Corporation | Axmi-150 delta-endotoxin gene and methods for its use |
| WO2010085295A2 (en) | 2009-01-23 | 2010-07-29 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with lepidopteran activity |
| BRPI1007915B1 (pt) | 2009-02-05 | 2019-05-14 | Athenix Corporation | Genes de variante axmi-r1 delta-endotoxina, vetor, célula hospedeira microbiana, polipeptídeo recombinante e seu método de produção, composição, e métodos para controlar e matar uma população de peste de coleópteros, 5 e para protegeruma planta de uma peste |
| CA3081727A1 (en) | 2009-02-27 | 2010-09-02 | BASF Agricultural Solutions Seed US LLC | Pesticidal proteins and methods for their use |
| US20100298211A1 (en) | 2009-03-11 | 2010-11-25 | Athenix Corporation | Axmi-001, axmi-002, axmi-030, axmi-035, and axmi-045: toxin genes and methods for their use |
| PL2419441T3 (pl) | 2009-04-17 | 2015-06-30 | Dow Agrosciences Llc | Owadzie toksyny Cry obejmujące DIG-3 |
| MX2011013674A (es) | 2009-06-16 | 2012-01-20 | Dow Agrosciences Llc | Toxinas cry dig-5 insecticidas. |
| JP2012532586A (ja) | 2009-06-16 | 2012-12-20 | ダウ アグロサイエンシィズ エルエルシー | Dig−11殺虫性cry毒素 |
| WO2010147879A1 (en) | 2009-06-16 | 2010-12-23 | Dow Agrosciences Llc | Dig-10 insecticidal cry toxins |
| CA2769643C (en) | 2009-07-31 | 2020-01-07 | Athenix Corp. | Axmi-192 family of pesticidal genes and methods for their use |
| CA2775582A1 (en) * | 2009-10-02 | 2011-04-07 | Syngenta Participations Ag | Insecticidal proteins |
| AR078964A1 (es) | 2009-11-12 | 2011-12-14 | Pioneer Hi Bred Int | Gen de bacillus thuringiensis que codifica polipeptido con actividad pesticida contra lepidoptera |
| BR112012014801B1 (pt) * | 2009-12-16 | 2024-03-05 | Dow Agrosciences Llc | Métodos para controlar o desenvolvimento da resistência de um inseto à uma proteína inseticida derivada de um bacillus thuringiensis, e para o controle de pragas de lepidópteros, bem como composição para o controle de pragas de lepidópteros |
| WO2011084324A2 (en) | 2009-12-21 | 2011-07-14 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with lepidopteran activity |
| CA2790023A1 (en) | 2010-02-18 | 2011-08-25 | Athenix Corp. | Axmi218, axmi219, axmi220, axmi226, axmi227, axmi228, axmi229, axmi230, and axmi231 delta-endotoxin genes and methods for their use |
| MX2012009632A (es) | 2010-02-18 | 2012-09-28 | Athenix Corp | Genes delta-endotoxinicos axmi221z, axmi222z, axmi223z, axmi224z, axmi225z y metodos para su uso. |
| WO2012024200A2 (en) | 2010-08-19 | 2012-02-23 | Pioneer Hi-Bred International, Inc. | Novel bacillus thuringiensis gene with lepidopteran activity |
| MX2013007532A (es) | 2010-12-28 | 2013-09-16 | Pioneer Hi Bred Int | Nuevo gen de bacillus thuringiensis con actividad contra el orden lepidoptera. |
| MX2013008392A (es) | 2011-01-24 | 2013-08-12 | Pioneer Hi Bred Int | Nuevos genes de bacillus thuringiensis con actividad lepidoptera. |
| US9328356B2 (en) | 2011-02-11 | 2016-05-03 | Monsanto Technology Llc | Pesticidal nucleic acids and proteins and uses thereof |
| CN103459601A (zh) | 2011-02-11 | 2013-12-18 | 先锋国际良种公司 | 具有对抗玉米根虫的活性的合成杀昆虫蛋白 |
| US8878007B2 (en) | 2011-03-10 | 2014-11-04 | Pioneer Hi Bred International Inc | Bacillus thuringiensis gene with lepidopteran activity |
| WO2012135436A1 (en) | 2011-03-30 | 2012-10-04 | Athenix Corp. | Axmi238 toxin gene and methods for its use |
| GB201105418D0 (en) | 2011-03-31 | 2011-05-18 | Univ Durham | Pesticide |
| CN109097376B (zh) | 2011-04-07 | 2022-09-09 | 孟山都技术公司 | 具有对抗半翅目和/或鳞翅目昆虫的活性的昆虫抑制毒素家族 |
| AR087367A1 (es) | 2011-07-28 | 2014-03-19 | Athenix Corp | Gen de la toxina axmi 270 y sus metodos de empleo |
| AR088746A1 (es) | 2011-07-28 | 2014-07-02 | Athenix Corp | Proteinas variantes de la toxina activa contra las larvas del gusano de la raiz del maiz del oeste (axmi205) |
| EP2737068A1 (en) | 2011-07-29 | 2014-06-04 | Athenix Corp. | Axmi279 pesticidal gene and methods for its use |
| UY34663A (es) | 2012-03-08 | 2013-10-31 | Athenix Corp | Acido nucleico y proteina recombinante del gen de la endotoxina axmi345, vectores, células, composiciones y métodos para proteger plantas |
| NZ727213A (en) | 2012-03-09 | 2020-03-27 | Vestaron Corp | Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides |
| BR112014024861B1 (pt) | 2012-04-06 | 2021-11-16 | Monsanto Technology Llc | Polipeptídeo inibidor de inseto, polinucleotídeo codificando o mesmo, célula hospedeira bacteriana, composição inibidora de inseto, mercadoria e métodos de controle de uma peste hemíptera e de produzir uma mercadoria |
| US9688730B2 (en) | 2012-07-02 | 2017-06-27 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| US9475847B2 (en) | 2012-07-26 | 2016-10-25 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| PY1346216A (es) * | 2012-10-05 | 2016-11-01 | Dow Agrosciences Llc | Uso de cry1ea en combinaciones para el control del insecto resistente gusano del ejército del otoño |
| US10487123B2 (en) | 2014-10-16 | 2019-11-26 | Monsanto Technology Llc | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests |
| JP6626102B2 (ja) | 2014-10-16 | 2019-12-25 | モンサント テクノロジー エルエルシー | 鱗翅目害虫に有毒または阻害性の新規キメラ殺虫性タンパク質 |
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