EA201892762A1 - Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей - Google Patents

Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей

Info

Publication number
EA201892762A1
EA201892762A1 EA201892762A EA201892762A EA201892762A1 EA 201892762 A1 EA201892762 A1 EA 201892762A1 EA 201892762 A EA201892762 A EA 201892762A EA 201892762 A EA201892762 A EA 201892762A EA 201892762 A1 EA201892762 A1 EA 201892762A1
Authority
EA
Eurasian Patent Office
Prior art keywords
insecticidal proteins
scrapped
pests
toxic
inhibitor
Prior art date
Application number
EA201892762A
Other languages
English (en)
Inventor
Джеймс А. Баум
Томас А. Черрути
Кристал Л. Дарт
Ли Х. Инглиш
Сяожань Фу
Виктор М. Гузов
Эрлин Р. Хау
Джей П. Моргенстерн
Джеймс К. Робертс
Сара А. Сальвадор
Цзиньлин Ван
Станислав Фласинский
Original Assignee
Монсанто Текнолоджи Ллс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Монсанто Текнолоджи Ллс filed Critical Монсанто Текнолоджи Ллс
Publication of EA201892762A1 publication Critical patent/EA201892762A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal protein (delta-endotoxin)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Cell Biology (AREA)
  • Insects & Arthropods (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

Раскрыты нуклеотидные последовательности, которые кодируют новые химерные инсектицидные белки, проявляющие ингибирующую активность в отношении чешуекрылых. Конкретные варианты реализации изобретения обеспечивают композиции и трансформированные растения, части растений и семена, содержащие рекомбинантные молекулы нуклеиновой кислоты, кодирующие один или более химерных инсектицидных белков.
EA201892762A 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей EA201892762A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462064989P 2014-10-16 2014-10-16

Publications (1)

Publication Number Publication Date
EA201892762A1 true EA201892762A1 (ru) 2019-04-30

Family

ID=54608929

Family Applications (5)

Application Number Title Priority Date Filing Date
EA201790843A EA034918B1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892762A EA201892762A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892761A EA201892761A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892760A EA201892760A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892763A EA201892763A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201790843A EA034918B1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей

Family Applications After (3)

Application Number Title Priority Date Filing Date
EA201892761A EA201892761A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892760A EA201892760A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей
EA201892763A EA201892763A1 (ru) 2014-10-16 2015-10-15 Новые химерные инсектицидные белки, токсичные или ингибиторные в отношении чешуекрылых-вредителей

Country Status (29)

Country Link
US (7) US10233217B2 (ru)
EP (5) EP3715362A1 (ru)
JP (1) JP6626102B2 (ru)
KR (5) KR102208978B1 (ru)
CN (5) CN112142857A (ru)
AR (6) AR103129A1 (ru)
AU (6) AU2015332384B2 (ru)
BR (4) BR122020004891B1 (ru)
CA (3) CA2964776A1 (ru)
CL (5) CL2017000895A1 (ru)
CO (1) CO2017004807A2 (ru)
CR (3) CR20210268A (ru)
CU (5) CU24541B1 (ru)
EA (5) EA034918B1 (ru)
EC (1) ECSP17029551A (ru)
ES (1) ES2864657T3 (ru)
IL (1) IL251570B (ru)
MX (5) MX2017004919A (ru)
MY (1) MY181627A (ru)
NI (1) NI201700044A (ru)
NZ (5) NZ768149A (ru)
PE (5) PE20220375A1 (ru)
PH (5) PH12017500697A1 (ru)
SG (5) SG11201702749RA (ru)
SV (1) SV2017005422A (ru)
UA (3) UA123480C2 (ru)
UY (1) UY36360A (ru)
WO (1) WO2016061391A2 (ru)
ZA (6) ZA201702191B (ru)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR122021024287B1 (pt) * 2013-12-09 2022-10-11 Athenix Corp Constructo, vetor, célula hospedeira bacteriana, polipeptídeo, composição, método de controle e exterminação de praga lepidóptera, método de proteção de planta e método de produção de polipeptídeo com atividade pesticida
EP3715362A1 (en) 2014-10-16 2020-09-30 Monsanto Technology LLC Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
EP3207050A4 (en) 2014-10-16 2018-09-12 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having improved activity spectrum and uses thereof
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
US10647995B2 (en) 2015-06-16 2020-05-12 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
WO2017030808A1 (en) 2015-08-18 2017-02-23 Monsanto Technology Llc Novel insect inhibitory proteins
PE20180781A1 (es) 2015-08-27 2018-05-07 Monsanto Technology Llc Proteinas inhibidoras de insectos novedosas
US10572836B2 (en) 2015-10-15 2020-02-25 International Business Machines Corporation Automatic time interval metadata determination for business intelligence and predictive analytics
CN109312359A (zh) 2016-06-16 2019-02-05 先锋国际良种公司 用以防治昆虫有害生物的组合物和方法
US20210292778A1 (en) 2016-07-12 2021-09-23 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US11016730B2 (en) 2016-07-28 2021-05-25 International Business Machines Corporation Transforming a transactional data set to generate forecasting and prediction insights
CN116333071A (zh) * 2016-10-21 2023-06-27 先锋国际良种公司 来自植物的杀昆虫蛋白及其使用方法
MX2019006560A (es) 2016-12-12 2019-08-26 Syngenta Participations Ag Proteinas pesticidas modificadas y metodos para controlar plagas de plantas.
CN110022676B (zh) * 2017-01-04 2023-07-25 先正达参股股份有限公司 用于控制植物有害生物的组合物和方法
CR20190367A (es) * 2017-01-12 2019-09-25 Monsanto Technology Llc Proteínas toxinas pesticidas activas contra insectos lepidópteros
WO2019074598A1 (en) 2017-10-13 2019-04-18 Pioneer Hi-Bred International, Inc. VIRUS-INDUCED GENETIC SILENCING TECHNOLOGY FOR THE CONTROL OF INSECTS IN MAIZE
CN108148841B (zh) * 2017-12-14 2020-12-29 云南大学 氨基酸序列在用于使昆虫Dip3蛋白失活中的应用
EP4122947A1 (en) 2017-12-19 2023-01-25 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides and uses thereof
US11525144B2 (en) * 2018-03-14 2022-12-13 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
AU2019234562A1 (en) * 2018-03-14 2020-09-10 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
CA3104156A1 (en) * 2018-07-30 2020-02-06 Monsanto Technology Llc Corn transgenic event mon 95379 and methods for detection and uses thereof
CN109198845A (zh) * 2018-08-21 2019-01-15 广州杰赛科技股份有限公司 全自主甲面彩绘装置、方法、设备及存储介质
BR112021003797A2 (pt) 2018-08-29 2021-05-25 Pioneer Hi-Bred International, Inc. proteínas inseticidas e métodos para seu uso
CN111100208A (zh) * 2020-01-16 2020-05-05 黑龙江大鹏农业有限公司 一种人工合成的抗虫蛋白mCry1Ia2及其制备方法和应用
WO2022125639A1 (en) 2020-12-08 2022-06-16 Monsanto Technology Llc Modified plant-associated bacteria and methods of their use
WO2022140227A1 (en) 2020-12-21 2022-06-30 Monsanto Technolgy Llc Novel insect inhibitory proteins
UY39585A (es) 2020-12-23 2022-07-29 Monsanto Technology Llc Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas
CN116848250A (zh) 2020-12-31 2023-10-03 孟山都技术公司 新型昆虫抑制蛋白
TW202305130A (zh) 2021-03-26 2023-02-01 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 原核系統中環狀多核糖核苷酸之產生
AR125217A1 (es) 2021-03-26 2023-06-28 Flagship Pioneering Innovations Vii Llc Producción de polirribonucleótidos circulares en un sistema procariota
WO2022204464A1 (en) 2021-03-26 2022-09-29 Flagship Pioneering Innovations Vii, Llc Production of circular polyribonucleotides in a eukaryotic system
CN114134171B (zh) * 2021-10-29 2023-09-15 隆平生物技术(海南)有限公司 一种抑制或杀灭东方黏虫的方法及其应用
AU2022375817A1 (en) 2021-11-01 2024-05-09 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
CN114507673A (zh) * 2022-01-20 2022-05-17 隆平生物技术(海南)有限公司 一种抑制或杀灭小地老虎的方法及应用
WO2023141540A2 (en) 2022-01-20 2023-07-27 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
CN116063431B (zh) * 2022-09-19 2023-11-10 隆平生物技术(海南)有限公司 一种植物抗虫蛋白质及其应用

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587548T2 (de) 1984-12-28 1993-12-23 Plant Genetic Systems Nv Rekombinante DNA, die in pflanzliche Zellen eingebracht werden kann.
EP0218571B1 (en) 1985-08-07 1993-02-03 Monsanto Company Glyphosate-resistant plants
US5312910A (en) 1987-05-26 1994-05-17 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase
ATE206462T1 (de) 1989-02-24 2001-10-15 Monsanto Technology Llc Synthetische pflanzengene und verfahren zu ihrer herstellung
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
FR2673643B1 (fr) 1991-03-05 1993-05-21 Rhone Poulenc Agrochimie Peptide de transit pour l'insertion d'un gene etranger dans un gene vegetal et plantes transformees en utilisant ce peptide.
US5723758A (en) * 1991-09-13 1998-03-03 Mycogen Corporation Bacillus thuringiensis genes encoding lepidopteran-active toxins
US5322687A (en) 1993-07-29 1994-06-21 Ecogen Inc. Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
GB9318207D0 (en) 1993-09-02 1993-10-20 Sandoz Ltd Improvements in or relating to organic compounds
US5508264A (en) * 1994-12-06 1996-04-16 Mycogen Corporation Pesticidal compositions
US6063756A (en) * 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6017534A (en) 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
AP9901541A0 (en) * 1996-11-20 1999-06-30 Ecogen Inc Broad-spectrum delta-endotoxins.
US6713063B1 (en) 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US5942664A (en) 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
US6218188B1 (en) 1997-11-12 2001-04-17 Mycogen Corporation Plant-optimized genes encoding pesticidal toxins
US6489542B1 (en) 1998-11-04 2002-12-03 Monsanto Technology Llc Methods for transforming plants to express Cry2Ab δ-endotoxins targeted to the plastids
US6283613B1 (en) 1999-07-29 2001-09-04 Cooper Technologies Company LED traffic light with individual LED reflectors
AU6702300A (en) * 1999-08-19 2001-03-19 Syngenta Participations Ag Hybrid insecticidal toxins and nucleic acid sequences coding therefor
US6501009B1 (en) 1999-08-19 2002-12-31 Monsanto Technology Llc Expression of Cry3B insecticidal protein in plants
US6593293B1 (en) * 1999-09-15 2003-07-15 Monsanto Technology, Llc Lepidopteran-active Bacillus thuringiensis δ-endotoxin compositions and methods of use
AU2000269030A1 (en) * 2000-08-11 2002-02-25 Monsanto Technology Llc Broad-spectrum delta-endotoxins
ES2243543T3 (es) * 2000-08-25 2005-12-01 Syngenta Participations Ag Hibridos de proteinas cristalinas de bacillus thurigiensis.
AR035799A1 (es) * 2001-03-30 2004-07-14 Syngenta Participations Ag Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos.
CN101385467B (zh) * 2001-03-30 2014-11-05 辛根塔参与股份公司 新的杀虫毒素
CA2911801A1 (en) * 2002-03-22 2003-10-02 Greta Arnaut Novel bacillus thuringiensis insecticidal proteins
AU2003265637A1 (en) 2002-08-29 2004-03-19 Natalia N. Bogdanova Nucleotide sequences encoding cry1bb proteins for enhanced expression in plants
CA2693280C (en) 2004-04-09 2017-09-12 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants
CN101001957B (zh) 2004-06-09 2012-07-04 先锋高级育种国际公司 质体转运肽
US7674959B2 (en) 2005-04-01 2010-03-09 Athenix Corporation Axmi-027, axmi-036 and axmi-038, a family of delta-endotoxin genes and methods for their use
ES2400809T3 (es) 2005-08-31 2013-04-12 Monsanto Technology Llc Secuencias de nucleótidos que codifican proteínas insecticidas
MX2009000775A (es) 2006-07-21 2009-02-23 Du Pont Metodo para identificar genes novedosos.
US7521235B2 (en) 2006-07-21 2009-04-21 Pioneer Hi-Bred International, Inc. Unique novel Bacillus thuringiensis gene with Lepidopteran activity
CL2007003582A1 (es) 2006-12-08 2008-06-20 Pioneer Hi Bred Int Acidos nucleicos codificantes de polipeptidos cry1 de bacillus thuringiensis; vector y celula huesped que lo comprenden; dichos polipeptidos; y metodo para producir una planta con resistencia a insectos mejorada.
US8044260B2 (en) 2007-03-09 2011-10-25 Monsanto Technology Llc Method of meristem excision and transformation
AU2008232826B2 (en) 2007-03-28 2011-06-02 Syngenta Participations Ag Insecticidal proteins
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
BRPI0811727A2 (pt) 2007-05-08 2014-10-07 Monsanto Technology Llc Métodos para induzir calo embriogênico do algodão.
US7772465B2 (en) 2007-06-26 2010-08-10 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis gene with lepidopteran activity
BRPI0815980A2 (pt) 2007-08-31 2015-06-16 Monsanto Technology Llc Métodos e aparelhos para isolar substancialmente tecidos de planta
US8283524B2 (en) 2008-05-15 2012-10-09 Pioneer Hi-Bred International, Inc Bacillus thuringiensis gene with lepidopteran activity
US8129594B2 (en) * 2008-06-11 2012-03-06 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis gene with lepidopteran activity
US8129593B2 (en) 2008-06-11 2012-03-06 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis gene with lepidopteran activity
AU2009262153B2 (en) 2008-06-25 2014-02-27 BASF Agricultural Solutions Seed US LLC Toxin genes and methods for their use
EP2297190A2 (en) 2008-07-02 2011-03-23 Athenix Corporation Axmi-115, axmi-113, axmi-005, axmi-163 and axmi-184: vip3a insecticidal proteins from bacillus thuringiensis and methods for their use
US8445749B2 (en) 2008-09-19 2013-05-21 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
US20100077507A1 (en) 2008-09-22 2010-03-25 Pioneer Hi-Bred International, Inc. Novel Bacillus Thuringiensis Gene with Lepidopteran Activity
EP2361307B1 (en) 2008-12-22 2014-09-24 Athenix Corporation Pesticidal genes from Brevibacillus and methods for their use
BRPI0923159A2 (pt) 2008-12-23 2018-08-28 Athenix Corp gene de delta-endotoxina axmi-150 e métodos para sua utilização.
US8692065B2 (en) 2009-01-23 2014-04-08 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
HUE032178T2 (en) 2009-02-05 2017-09-28 Athenix Corp Variable Axmi-Rl delta-endotoxin genes and methods for their use
EP2957638B1 (en) 2009-02-27 2018-12-12 Athenix Corporation Pesticidal proteins and methods for their use
CA2754845A1 (en) 2009-03-11 2010-12-09 Athenix Corporation Axmi-030 insecticidal protein from bacillus thuringiensis and methods for use
AU2010236944B2 (en) * 2009-04-17 2016-07-21 Dow Agrosciences Llc DIG-3 insecticidal Cry toxins
CN103002744A (zh) 2009-06-16 2013-03-27 陶氏益农公司 Dig-11杀虫cry毒素
CA2765742A1 (en) 2009-06-16 2010-12-23 Justin Lira Dig-10 insecticidal cry toxins
EP2443140A4 (en) 2009-06-16 2013-04-03 Dow Agrosciences Llc INSECTICIDES DIG-5-CRY-TOXINE
EA035563B1 (ru) 2009-07-31 2020-07-08 Басф Агрикалчерал Солюшнс Сид Юс Ллк Молекула рекомбинантной нуклеиновой кислоты, кодирующей полипептид с пестицидной активностью против чешуекрылых, жесткокрылых или нематодных вредителей, ее получение и применение
CN102596988B (zh) * 2009-10-02 2016-07-13 先正达参股股份有限公司 杀虫蛋白
BR112012011222A2 (pt) 2009-11-12 2015-09-15 Pioneer Hi Bred Int molécula de ácido nucleico isolada, contruto de dna, célula hospedeira, planta transgênica, semente transformada, polipeptídeo isolado com atividade pesticida, composição e métodos para controlar uma população de praga de lepidópteros, para matar uma praga de lepidóptero e para proteger uma planta contra uma praga
DK2512222T3 (en) * 2009-12-16 2018-03-26 Dow Agrosciences Llc COMBINED USE OF CRY1CA AND CRY1FA PROTEINS FOR MANAGING INSECT RESISTANCE
US8586832B2 (en) 2009-12-21 2013-11-19 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with Lepidopteran activity
WO2011103248A2 (en) 2010-02-18 2011-08-25 Athenix Corp. AXMI221z, AXMI222z, AXMI223z, AXMI224z, AND AXMI225z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE
EP2536266A2 (en) 2010-02-18 2012-12-26 Athenix Corp. Axmi218, axmi219, axmi220, axmi226, axmi227, axmi228, axmi229, axmi230, and axmi231 delta-endotoxin genes and methods for their use
CN103154247A (zh) 2010-08-19 2013-06-12 先锋国际良种公司 对鳞翅目昆虫具有活性的新苏云金杆菌基因
BR112013015515A2 (pt) 2010-12-28 2018-04-24 Pioneer Hi Bred Int molécula de ácido nucleico isolada, construto de dna, célula hospedeira, planta transgênica, semente transformada da planta, polipeptídeo isolado com atividade pesticida, composição, método para controlar uma população de praga de lepidóptero, método para matar uma praga de lepidóptero, método para produzir um polipeptídeo com atividade pesticida, planta que tem incorporado de maneira estável em seu genoma um construto de dna, método para proteger uma planta contra uma praga
WO2012102999A1 (en) 2011-01-24 2012-08-02 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis genes with lepidopteran activity
US9328356B2 (en) * 2011-02-11 2016-05-03 Monsanto Technology Llc Pesticidal nucleic acids and proteins and uses thereof
WO2012109515A1 (en) 2011-02-11 2012-08-16 Pioneer Hi-Bred International, Inc. Synthetic insecticidal proteins active against corn rootworm
US8878007B2 (en) 2011-03-10 2014-11-04 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
US9321814B2 (en) 2011-03-30 2016-04-26 Athenix Corp. AXMI238 toxin gene and methods for its use
GB201105418D0 (en) 2011-03-31 2011-05-18 Univ Durham Pesticide
CN109097376B (zh) 2011-04-07 2022-09-09 孟山都技术公司 具有对抗半翅目和/或鳞翅目昆虫的活性的昆虫抑制毒素家族
UY34227A (es) 2011-07-28 2013-02-28 Athenix Corp Acido nucleico recombinante que codifica el gen de la toxina axmi270, vectores, células, plantas y sus métodos de empleo
BR112014001978B8 (pt) 2011-07-28 2022-07-05 Athenix Corp Molécula de ácido nucleico recombinante, célula hospedeira, polipeptídeo, composição, métodos para controle, para proteção e para exterminação de uma população de pragas de lepidópteros ou coleópteros, método para produção de um polipeptídeo com atividade pesticida e método para aumentar a produtividade de uma planta
AR087366A1 (es) 2011-07-29 2014-03-19 Athenix Corp Gen plaguicida axmi 279 y sus metodos de empleo
CN104302663B (zh) 2012-03-08 2018-03-27 阿森尼克斯公司 AXMI345 δ‑内毒素基因及其使用方法
NZ727213A (en) 2012-03-09 2020-03-27 Vestaron Corp Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
EP2834266B1 (en) 2012-04-06 2019-06-12 Monsanto Technology LLC Proteins toxic to hemipteran insect species
US9688730B2 (en) 2012-07-02 2017-06-27 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US9475847B2 (en) 2012-07-26 2016-10-25 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
AP2015008351A0 (en) * 2012-10-05 2015-04-30 Dow Agrosciences Llc Use of cry1ea in combinations for management of resistant fall armyworm insects
EP3715362A1 (en) 2014-10-16 2020-09-30 Monsanto Technology LLC Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests

Also Published As

Publication number Publication date
NZ768150A (en) 2023-12-22
US20160108428A1 (en) 2016-04-21
ZA201900217B (en) 2020-10-28
CU20180053A7 (es) 2018-07-05
EP3715361A1 (en) 2020-09-30
KR20190142455A (ko) 2019-12-26
JP2017533700A (ja) 2017-11-16
NZ768153A (en) 2023-12-22
WO2016061391A3 (en) 2016-07-21
SG11201702749RA (en) 2017-05-30
CU24571B1 (es) 2022-01-13
MX2017004919A (es) 2017-06-22
KR20170068567A (ko) 2017-06-19
US10669317B2 (en) 2020-06-02
EP3207049B1 (en) 2021-01-27
CR20210268A (es) 2021-07-14
PE20170895A1 (es) 2017-07-12
AU2019203025A1 (en) 2019-05-23
CL2019000112A1 (es) 2019-07-12
CU24456B1 (es) 2019-11-04
KR102208978B1 (ko) 2021-01-27
AR118892A2 (es) 2021-11-10
CR20170198A (es) 2017-06-29
PH12021500022A1 (en) 2021-12-13
AR118891A2 (es) 2021-11-10
PH12021500021A1 (en) 2021-12-13
EA201790843A1 (ru) 2017-08-31
AU2020202394C1 (en) 2021-01-07
JP6626102B2 (ja) 2019-12-25
UA123480C2 (uk) 2021-04-07
BR112017007794B1 (pt) 2024-01-30
ZA202001769B (en) 2021-09-29
EP3715362A1 (en) 2020-09-30
EP3715363A1 (en) 2020-09-30
CU20180052A7 (es) 2018-07-05
AR118893A2 (es) 2021-11-10
PH12021500019A1 (en) 2021-12-13
EP3207049A2 (en) 2017-08-23
AU2020202394A1 (en) 2020-04-30
US20180127774A1 (en) 2018-05-10
EA201892760A1 (ru) 2019-04-30
KR20190142453A (ko) 2019-12-26
EP3715364A1 (en) 2020-09-30
BR122020004897B1 (pt) 2024-01-30
US11267849B2 (en) 2022-03-08
KR102208984B1 (ko) 2021-01-27
PH12017500697A1 (en) 2017-10-09
AU2019203014A1 (en) 2019-05-23
US20180127775A1 (en) 2018-05-10
CL2019000110A1 (es) 2019-07-12
BR112017007794A2 (pt) 2018-01-16
CL2019000109A1 (es) 2019-07-12
KR102208985B1 (ko) 2021-01-27
CU20170049A7 (es) 2017-10-05
BR122020004891B1 (pt) 2024-01-30
AU2020202394B2 (en) 2020-10-01
CN112175093A (zh) 2021-01-05
SV2017005422A (es) 2018-03-01
AR103129A1 (es) 2017-04-19
MX2021009320A (es) 2021-09-08
CU24541B1 (es) 2021-08-06
UA123482C2 (uk) 2021-04-07
US20220306703A1 (en) 2022-09-29
KR20190142456A (ko) 2019-12-26
SG10201913859XA (en) 2020-03-30
AR118894A2 (es) 2021-11-10
AU2019203014B2 (en) 2020-03-12
AU2015332384A1 (en) 2017-04-20
AU2019203025B2 (en) 2020-03-12
NZ768149A (en) 2023-12-22
ES2864657T3 (es) 2021-10-14
ZA202001768B (en) 2021-09-29
US10494409B2 (en) 2019-12-03
CO2017004807A2 (es) 2017-10-20
MX2021009317A (es) 2021-09-08
UY36360A (es) 2016-06-01
CR20210269A (es) 2021-07-14
US20200277340A1 (en) 2020-09-03
SG10201913849RA (en) 2020-03-30
CA2964776A1 (en) 2016-04-21
KR20190142454A (ko) 2019-12-26
CN107074974A (zh) 2017-08-18
ZA202001770B (en) 2021-09-29
IL251570B (en) 2021-05-31
AU2019203021B2 (en) 2020-03-12
CA3151123A1 (en) 2016-04-21
AR118890A2 (es) 2021-11-10
WO2016061391A2 (en) 2016-04-21
CN107074974B (zh) 2022-01-11
EA201892761A1 (ru) 2019-04-30
CU20180051A7 (es) 2018-07-05
AU2019203021A1 (en) 2019-05-23
NZ730747A (en) 2023-07-28
PE20220375A1 (es) 2022-03-16
IL251570A0 (en) 2017-06-29
MY181627A (en) 2020-12-30
US20180127773A1 (en) 2018-05-10
PE20220374A1 (es) 2022-03-16
BR122020004875B1 (pt) 2024-01-30
KR102208980B1 (ko) 2021-01-27
NI201700044A (es) 2017-06-12
EA201892763A1 (ru) 2019-04-30
SG10201913879PA (en) 2020-03-30
PE20220940A1 (es) 2022-05-31
CU20180054A7 (es) 2018-07-05
ZA202001771B (en) 2021-09-29
CN112142857A (zh) 2020-12-29
MX2021009318A (es) 2021-09-08
PH12021500020A1 (en) 2021-12-13
NZ768151A (en) 2023-12-22
US10494408B2 (en) 2019-12-03
CU24551B1 (es) 2021-11-04
MX2021009319A (es) 2021-09-08
SG10201913870RA (en) 2020-03-30
CL2017000895A1 (es) 2017-10-20
AU2015332384B2 (en) 2019-02-07
PE20220372A1 (es) 2022-03-16
AU2019203015A1 (en) 2019-05-23
ECSP17029551A (es) 2018-01-31
AU2019203015B2 (en) 2020-03-12
CL2019001328A1 (es) 2019-07-12
CN112142858A (zh) 2020-12-29
CN112175094A (zh) 2021-01-05
US20180127772A1 (en) 2018-05-10
UA123481C2 (uk) 2021-04-07
CU24570B1 (es) 2022-01-13
CA3151125A1 (en) 2016-04-21
ZA201702191B (en) 2021-06-30
EA034918B1 (ru) 2020-04-07
US10611806B2 (en) 2020-04-07
KR102127553B1 (ko) 2020-06-29
US10233217B2 (en) 2019-03-19

Similar Documents

Publication Publication Date Title
PH12021500019A1 (en) Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
PH12017500696A1 (en) Lepidopteran-active cry1da1 amino acid sequence variant proteins