JP2017531634A5 - - Google Patents
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- Publication number
- JP2017531634A5 JP2017531634A5 JP2017517121A JP2017517121A JP2017531634A5 JP 2017531634 A5 JP2017531634 A5 JP 2017531634A5 JP 2017517121 A JP2017517121 A JP 2017517121A JP 2017517121 A JP2017517121 A JP 2017517121A JP 2017531634 A5 JP2017531634 A5 JP 2017531634A5
- Authority
- JP
- Japan
- Prior art keywords
- rebaudioside
- udp
- glucose
- reaction mixture
- glycosyltransferase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059498P | 2014-10-03 | 2014-10-03 | |
| US62/059,498 | 2014-10-03 | ||
| US201462098929P | 2014-12-31 | 2014-12-31 | |
| US62/098,929 | 2014-12-31 | ||
| PCT/US2015/053777 WO2016054540A1 (en) | 2014-10-03 | 2015-10-02 | Non-caloric sweeteners and methods for synthesizing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531634A JP2017531634A (ja) | 2017-10-26 |
| JP2017531634A5 true JP2017531634A5 (https=) | 2018-10-18 |
| JP6883512B2 JP6883512B2 (ja) | 2021-06-09 |
Family
ID=55631622
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517085A Active JP6774945B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017516928A Expired - Fee Related JP6854238B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017517349A Active JP6722177B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017517121A Expired - Fee Related JP6883512B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517085A Active JP6774945B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017516928A Expired - Fee Related JP6854238B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017517349A Active JP6722177B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (22) | US10023604B2 (https=) |
| EP (4) | EP3200615B1 (https=) |
| JP (4) | JP6774945B2 (https=) |
| KR (4) | KR102557670B1 (https=) |
| CN (7) | CN106715451B (https=) |
| AU (4) | AU2015327858B2 (https=) |
| BR (3) | BR112017006139B1 (https=) |
| CA (4) | CA2958105C (https=) |
| DK (3) | DK3200615T3 (https=) |
| ES (3) | ES2693371T3 (https=) |
| HU (2) | HUE045992T2 (https=) |
| MX (4) | MX378831B (https=) |
| MY (4) | MY179680A (https=) |
| WO (4) | WO2016054534A1 (https=) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201505597SA (en) | 2013-02-06 | 2015-08-28 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US9522929B2 (en) | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| US10264811B2 (en) | 2014-05-19 | 2019-04-23 | Epc Natural Products Co., Ltd. | Stevia sweetener with improved solubility |
| DK3200615T3 (da) | 2014-10-03 | 2019-08-19 | Conagen Inc | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
| EP3232817A4 (en) | 2014-12-17 | 2018-10-10 | Cargill, Incorporated | Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility |
| SG11201705606PA (en) | 2015-01-30 | 2017-08-30 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| EP3718417B1 (en) | 2015-04-03 | 2025-09-03 | DSM IP Assets B.V. | Steviol glycosides |
| JP6793957B2 (ja) | 2015-04-14 | 2020-12-02 | コナゲン インコーポレイテッド | 改変された全細胞触媒を用いたノンカロリー甘味料の生成 |
| US20190203244A1 (en) * | 2015-08-20 | 2019-07-04 | Pepsico, Inc. | Preparation of rebaudioside m in a single reaction vessel |
| US10982249B2 (en) | 2016-04-13 | 2021-04-20 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| MX2018015534A (es) | 2016-06-15 | 2019-03-14 | Codexis Inc | Beta-glucosidasas dise?adas y metodos de glucosilacion. |
| JP2019517812A (ja) * | 2016-06-17 | 2019-06-27 | カーギル インコーポレイテッド | 経口摂取または経口使用のためのステビオールグリコシド組成物 |
| AU2017308143B2 (en) | 2016-08-12 | 2022-04-07 | Amyris, Inc. | UDP-dependent glycosyltransferase for high efficiency production of rebaudiosides |
| CN110191643B (zh) * | 2016-10-14 | 2023-06-06 | 科纳根公司 | 甜菊醇糖苷的生物合成生产及其工艺 |
| BR112019008048A2 (pt) | 2016-10-21 | 2019-07-02 | Pepsico Inc | método para preparar rebaudiosídeo n com o uso de método enzimático |
| US11359222B2 (en) | 2016-10-21 | 2022-06-14 | Pepsico, Inc. | Enzymatic method for preparing Rebaudioside j |
| WO2018093196A1 (ko) * | 2016-11-17 | 2018-05-24 | 서울대학교산학협력단 | 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체 |
| BR112019011200B1 (pt) | 2016-12-01 | 2021-12-28 | Arvinas Operations, Inc | Derivados de tetrahidronaftaleno e tetrahidroisoquinolina como degradadores do receptor de estrogênio |
| CA3175070A1 (en) | 2017-02-03 | 2018-08-09 | Codexis, Inc. | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
| ES3042101T3 (en) * | 2017-04-25 | 2025-11-18 | Coca Cola Co | Sweetness and taste improvement of steviol glycoside and mogroside sweeteners with dihydrochalcones |
| CN107164435B (zh) * | 2017-05-27 | 2020-03-31 | 中国药科大学 | 一种莱鲍迪苷ka的制备方法 |
| WO2018225817A1 (ja) | 2017-06-08 | 2018-12-13 | サントリーホールディングス株式会社 | 甘味の増大した飲食品 |
| MX2019015404A (es) | 2017-06-30 | 2020-07-20 | Conagen Inc | Hidrólisis de glucósidos de esteviol por beta-glucosidasa. |
| CN111868252B (zh) | 2018-03-12 | 2025-06-03 | 科纳根公司 | 甜菊糖苷莱苞迪苷j和莱苞迪苷n的生物合成生产 |
| CN112135527B (zh) * | 2018-05-08 | 2023-08-15 | 伊比西(北京)植物药物技术有限公司 | 具有改善风味的甜菊醇糖甙组合物 |
| CN109021038B (zh) * | 2018-06-11 | 2021-07-27 | 江西师范大学 | 一种甜菊糖苷的制备方法 |
| WO2020028039A1 (en) * | 2018-07-30 | 2020-02-06 | Codexis, Inc. | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
| JP6887025B2 (ja) * | 2018-08-17 | 2021-06-16 | 邦泰生物工程（深▲セン▼）有限公司 | 安定型ニコチンアミドリボシド組成物及びその調製方法 |
| CN111073923A (zh) * | 2018-10-22 | 2020-04-28 | 山东三元生物科技股份有限公司 | 一种莱鲍迪苷m的酶法制备方法 |
| CN113302298B (zh) | 2018-11-09 | 2025-02-25 | 银杏生物制品公司 | 罗汉果甙的生物合成 |
| EP3892107A4 (en) * | 2018-12-07 | 2022-09-14 | Suntory Holdings Limited | COFFEE BEVERAGE WITH IMPROVED TASTE QUALITY PROVIDED BY SUGAR AND SWEETENER |
| WO2020116664A1 (en) * | 2018-12-07 | 2020-06-11 | Suntory Holdings Limited | Composition |
| CN113163789A (zh) * | 2018-12-07 | 2021-07-23 | 三得利控股株式会社 | 糖及甜味剂所呈现的味质得到改善的咖啡饮料 |
| SG11202105335UA (en) * | 2018-12-07 | 2021-06-29 | Suntory Holdings Ltd | Composition |
| MX2021006986A (es) * | 2018-12-12 | 2021-08-16 | Conagen Inc | Produccion biosintetica de variantes de glucosidos de esteviol. |
| CN109750072B (zh) * | 2019-01-31 | 2022-04-19 | 南京工业大学 | 一种酶法制备莱鲍迪苷e的方法 |
| EP3799057A1 (en) | 2019-09-25 | 2021-03-31 | Koninklijke Philips N.V. | Prediction tool for patient immune response to a therapy |
| EP4044823A4 (en) * | 2019-10-16 | 2024-04-24 | Sweegen, Inc. | STEVIOL GLYCOSIDE FORMULATIONS FOR FOOD AND BEVERAGES |
| CN110846363B (zh) * | 2019-11-11 | 2023-02-17 | 天津大学 | 一锅法生产莱鲍迪苷d的方法 |
| CN110872586B (zh) * | 2019-11-11 | 2024-01-30 | 天津大学 | 固定化葡萄糖基转移酶及制备方法及催化生产莱鲍迪苷d的方法 |
| CN110734944B (zh) * | 2019-11-11 | 2023-02-21 | 中化健康产业发展有限公司 | 一步法合成莱鲍迪苷m的方法 |
| CN110846305B (zh) * | 2019-11-11 | 2023-11-28 | 中化健康产业发展有限公司 | 一种固定化糖基转移酶催化莱鲍迪苷a生成莱鲍迪苷m的方法 |
| CA3171399A1 (en) * | 2020-03-13 | 2021-09-16 | Stanley W. HERRMANN | Rebaudioside m sweetener compositions |
| KR20230005877A (ko) * | 2020-04-20 | 2023-01-10 | 더 코카콜라 컴파니 | 향미가 증강된 시아메노사이드 i를 포함하는 음료 |
| US20250320470A1 (en) * | 2020-12-23 | 2025-10-16 | Samyang Corporation | Glycosyltransferase and steviol glucoside preparation method using same |
| JP7210626B2 (ja) * | 2021-02-18 | 2023-01-23 | ペプシコ・インク | 酵素的方法を使用してレバウディオサイドｊを調製するための方法 |
| WO2023121426A1 (ko) * | 2021-12-24 | 2023-06-29 | 주식회사 삼양사 | 레바우디오사이드의 생산 |
| WO2023183832A1 (en) | 2022-03-23 | 2023-09-28 | Sweegen, Inc. | Sweetener comprising rebaudiose m and brazzein |
| CN114921434B (zh) * | 2022-05-27 | 2024-02-20 | 中化健康产业发展有限公司 | 催化Reb A生产Reb M的重组糖基转移酶 |
| DE202022103252U1 (de) | 2022-06-09 | 2022-07-01 | Wal Ankita | Eine natürliche Süßstoffzusammensetzung als Süßungsmittel für Diabetes |
| CN116076694B (zh) * | 2022-10-12 | 2024-06-28 | 四川盈嘉合生科技有限公司 | 一种甜菊糖苷甜味剂及其制备方法 |
| CN121465226A (zh) * | 2023-09-15 | 2026-02-06 | 郑州大学 | 呈味肽及其筛选 |
| WO2025143773A1 (ko) * | 2023-12-26 | 2025-07-03 | 주식회사 삼양사 | 수크로우스 합성효소 변이체, udp-글루코실트랜스퍼라제 변이체 및 이들의 스테비올 배당체 생산 용도 |
| KR102777875B1 (ko) * | 2024-10-22 | 2025-03-13 | 대한민국 | 신규 페디오코커스 속 균주 및 그의 용도 |
| CN119842657B (zh) * | 2025-03-18 | 2025-05-27 | 青岛奔月生物技术有限公司 | 蔗糖合酶突变体及其应用 |
| CN120813686A (zh) * | 2025-05-07 | 2025-10-17 | 邦泰生物工程(深圳)有限公司 | 一种udp-葡萄糖基转移酶突变体及其制备莱鲍迪苷d的方法 |
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| US17804A (en) * | 1857-07-14 | Improvement in locks | ||
| US4612942A (en) | 1984-03-08 | 1986-09-23 | Stevia Company, Inc. | Flavor enhancing and modifying materials |
| JPH04149191A (ja) * | 1990-10-09 | 1992-05-22 | Nakano Vinegar Co Ltd | ステビオサイド糖転移化合物及びその製造方法 |
| US20090183270A1 (en) | 2002-10-02 | 2009-07-16 | Adams Thomas R | Transgenic plants with enhanced agronomic traits |
| US9107436B2 (en) | 2011-02-17 | 2015-08-18 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| US20100092638A1 (en) | 2006-10-24 | 2010-04-15 | Chad Allen Hansen | Consumables |
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| US8277862B2 (en) | 2007-03-14 | 2012-10-02 | Concentrate Manufacturing Company Of Ireland | Beverage products having steviol glycosides and at least one acid |
| CN107033200A (zh) * | 2008-10-03 | 2017-08-11 | 守田化学工业株式会社 | 新的甜菊醇糖苷 |
| US8501261B2 (en) * | 2010-05-21 | 2013-08-06 | Purecircle Sdn Bhd | High-purity Rebaudioside C and process for purification of the same |
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| CA2819253A1 (en) * | 2010-11-30 | 2012-06-07 | Massachusetts Institute Of Technology | Microbial production of natural sweeteners, diterpenoid steviol glycosides |
| CN108396044A (zh) | 2011-08-08 | 2018-08-14 | 埃沃尔瓦公司 | 甜菊醇糖苷类的重组生产 |
| EP3009010B1 (en) * | 2011-12-19 | 2020-02-05 | PureCircle SDN BHD | Methods for purifying steviol glycosides |
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| BR112014028819A2 (pt) * | 2012-05-22 | 2017-07-25 | Purecircle Sdn Bhd | glicosídeos de esteviol de pureza elevada |
| CN103710318B (zh) * | 2012-09-29 | 2017-01-18 | 中国科学院上海生命科学研究院 | 利用微生物生产甜菊糖苷类化合物的方法 |
| SG11201505597SA (en) | 2013-02-06 | 2015-08-28 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| CA2900882A1 (en) | 2013-02-11 | 2014-08-14 | Evolva Sa | Efficient production of steviol glycosides in recombinants hosts |
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| TWI657746B (zh) | 2013-06-19 | 2019-05-01 | 美商科納根股份有限公司 | 含有甜葉菊苷ｅ之可食用產品及使用其製備和強化可食用產品之甜味的方法 |
| EP3021689B1 (en) | 2013-07-15 | 2021-03-24 | DSM IP Assets B.V. | Diterpene production |
| CN103397064B (zh) * | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
| ES2709439T3 (es) | 2013-11-01 | 2019-04-16 | Conagen Inc | Producción recombinante de glucósidos de esteviol |
| EP3508584A1 (en) | 2014-01-28 | 2019-07-10 | PepsiCo, Inc. | Method for preparing rebaudioside m by using enzyme method |
| US9522929B2 (en) * | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| EP3202269B1 (en) * | 2014-09-30 | 2020-04-08 | Suntory Holdings Limited | Carbonated beverage, syrup to be used for preparing carbonated beverage, method for manufacturing carbonated beverage, and method for suppressing generation of bubbles in carbonated beverage |
| DK3200615T3 (da) | 2014-10-03 | 2019-08-19 | Conagen Inc | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
| JP6793957B2 (ja) * | 2015-04-14 | 2020-12-02 | コナゲン インコーポレイテッド | 改変された全細胞触媒を用いたノンカロリー甘味料の生成 |
| JP2019517812A (ja) * | 2016-06-17 | 2019-06-27 | カーギル インコーポレイテッド | 経口摂取または経口使用のためのステビオールグリコシド組成物 |
| CN110191643B (zh) * | 2016-10-14 | 2023-06-06 | 科纳根公司 | 甜菊醇糖苷的生物合成生产及其工艺 |
| MX2021006986A (es) * | 2018-12-12 | 2021-08-16 | Conagen Inc | Produccion biosintetica de variantes de glucosidos de esteviol. |
| EP4044823A4 (en) * | 2019-10-16 | 2024-04-24 | Sweegen, Inc. | STEVIOL GLYCOSIDE FORMULATIONS FOR FOOD AND BEVERAGES |
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2015
- 2015-10-02 DK DK15846977.5T patent/DK3200615T3/da active
- 2015-10-02 MX MX2017004246A patent/MX378831B/es unknown
- 2015-10-02 US US14/873,476 patent/US10023604B2/en active Active
- 2015-10-02 CN CN201580052182.XA patent/CN106715451B/zh active Active
- 2015-10-02 AU AU2015327858A patent/AU2015327858B2/en not_active Ceased
- 2015-10-02 ES ES15847221.7T patent/ES2693371T3/es active Active
- 2015-10-02 WO PCT/US2015/053767 patent/WO2016054534A1/en not_active Ceased
- 2015-10-02 KR KR1020177008543A patent/KR102557670B1/ko active Active
- 2015-10-02 CN CN201580051860.0A patent/CN106714578B/zh active Active
- 2015-10-02 CA CA2958105A patent/CA2958105C/en active Active
- 2015-10-02 BR BR112017006139-2A patent/BR112017006139B1/pt active IP Right Grant
- 2015-10-02 AU AU2015327862A patent/AU2015327862B2/en not_active Ceased
- 2015-10-02 MX MX2017004245A patent/MX367090B/es active IP Right Grant
- 2015-10-02 CN CN202210685584.5A patent/CN114908135B/zh active Active
- 2015-10-02 CA CA2958093A patent/CA2958093C/en active Active
- 2015-10-02 HU HUE15846977A patent/HUE045992T2/hu unknown
- 2015-10-02 ES ES15847668T patent/ES2869823T3/es active Active
- 2015-10-02 EP EP15846977.5A patent/EP3200615B1/en active Active
- 2015-10-02 EP EP15847668.9A patent/EP3201351B1/en active Active
- 2015-10-02 KR KR1020177008544A patent/KR102521967B1/ko active Active
- 2015-10-02 MY MYPI2017701154A patent/MY179680A/en unknown
- 2015-10-02 AU AU2015327854A patent/AU2015327854B2/en not_active Ceased
- 2015-10-02 KR KR1020177008546A patent/KR102536036B1/ko active Active
- 2015-10-02 JP JP2017517085A patent/JP6774945B2/ja active Active
- 2015-10-02 MY MYPI2017701156A patent/MY183062A/en unknown
- 2015-10-02 CN CN201580052483.2A patent/CN106795547B/zh active Active
- 2015-10-02 US US14/873,470 patent/US9850270B2/en not_active Expired - Fee Related
- 2015-10-02 CA CA2958437A patent/CA2958437C/en active Active
- 2015-10-02 HU HUE15847668A patent/HUE053331T2/hu unknown
- 2015-10-02 MY MYPI2017701146A patent/MY190567A/en unknown
- 2015-10-02 WO PCT/US2015/053782 patent/WO2016054544A1/en not_active Ceased
- 2015-10-02 WO PCT/US2015/053789 patent/WO2016054548A1/en not_active Ceased
- 2015-10-02 WO PCT/US2015/053777 patent/WO2016054540A1/en not_active Ceased
- 2015-10-02 US US14/873,481 patent/US9783566B2/en active Active
- 2015-10-02 US US14/873,474 patent/US9567619B2/en active Active
- 2015-10-02 JP JP2017516928A patent/JP6854238B2/ja not_active Expired - Fee Related
- 2015-10-02 JP JP2017517349A patent/JP6722177B2/ja active Active
- 2015-10-02 MX MX2017004248A patent/MX389979B/es unknown
- 2015-10-02 CN CN201580053379.5A patent/CN106795195B/zh active Active
- 2015-10-02 EP EP15845748.1A patent/EP3201211B1/en active Active
- 2015-10-02 CA CA2958434A patent/CA2958434C/en active Active
- 2015-10-02 ES ES15846977T patent/ES2741741T3/es active Active
- 2015-10-02 AU AU2015327940A patent/AU2015327940B2/en not_active Ceased
- 2015-10-02 BR BR112017006163-5A patent/BR112017006163B1/pt active IP Right Grant
- 2015-10-02 BR BR112017006155-4A patent/BR112017006155A2/pt not_active Application Discontinuation
- 2015-10-02 EP EP15847221.7A patent/EP3201212B1/en active Active
- 2015-10-02 JP JP2017517121A patent/JP6883512B2/ja not_active Expired - Fee Related
- 2015-10-02 MY MYPI2017701153A patent/MY182725A/en unknown
- 2015-10-02 CN CN202110535948.7A patent/CN113603736A/zh active Pending
- 2015-10-02 CN CN202211009324.2A patent/CN115918884B/zh active Active
- 2015-10-02 DK DK15847668.9T patent/DK3201351T3/da active
- 2015-10-02 DK DK15847221.7T patent/DK3201212T3/en active
- 2015-10-02 KR KR1020177008545A patent/KR102526446B1/ko active Active
- 2015-10-02 MX MX2017004247A patent/MX368414B/es active IP Right Grant
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2016
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2017
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2018
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2020
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2021
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2022
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