JP2017522882A5 - - Google Patents
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- JP2017522882A5 JP2017522882A5 JP2017503918A JP2017503918A JP2017522882A5 JP 2017522882 A5 JP2017522882 A5 JP 2017522882A5 JP 2017503918 A JP2017503918 A JP 2017503918A JP 2017503918 A JP2017503918 A JP 2017503918A JP 2017522882 A5 JP2017522882 A5 JP 2017522882A5
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- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims description 58
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028664P | 2014-07-24 | 2014-07-24 | |
| US62/028,664 | 2014-07-24 | ||
| US201462044103P | 2014-08-29 | 2014-08-29 | |
| US62/044,103 | 2014-08-29 | ||
| US201562152575P | 2015-04-24 | 2015-04-24 | |
| US62/152,575 | 2015-04-24 | ||
| PCT/US2015/041722 WO2016014789A2 (en) | 2014-07-24 | 2015-07-23 | Bcma chimeric antigen receptors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522882A JP2017522882A (ja) | 2017-08-17 |
| JP2017522882A5 true JP2017522882A5 (OSRAM) | 2018-07-12 |
| JP6706244B2 JP6706244B2 (ja) | 2020-06-03 |
Family
ID=55163965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017503918A Active JP6706244B2 (ja) | 2014-07-24 | 2015-07-23 | Bcmaキメラ抗原受容体 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20170226216A1 (OSRAM) |
| EP (1) | EP3172231B1 (OSRAM) |
| JP (1) | JP6706244B2 (OSRAM) |
| KR (1) | KR102523934B1 (OSRAM) |
| CN (1) | CN106795217B (OSRAM) |
| AU (1) | AU2015292590B2 (OSRAM) |
| CA (1) | CA2956002C (OSRAM) |
| ES (1) | ES2878449T3 (OSRAM) |
| IL (1) | IL250202B (OSRAM) |
| MX (1) | MX2017001079A (OSRAM) |
| RU (1) | RU2747457C2 (OSRAM) |
| SG (2) | SG10201900455YA (OSRAM) |
| WO (1) | WO2016014789A2 (OSRAM) |
| ZA (1) | ZA201700730B (OSRAM) |
Families Citing this family (246)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3134432B1 (en) | 2014-04-25 | 2019-12-25 | Bluebird Bio, Inc. | Mnd promoter chimeric antigen receptors |
| RS60544B1 (sr) | 2014-04-25 | 2020-08-31 | Bluebird Bio Inc | Poboljšani metodi za proizvodnju adoptivnih ćelijskih terapija |
| CN106535925A (zh) | 2014-05-23 | 2017-03-22 | 佛罗里达大学研究基金会有限公司 | 基于car的免疫治疗 |
| US10479975B2 (en) | 2014-06-06 | 2019-11-19 | Bluebird Bio, Inc. | Methods of making T cell compositions |
| JP7054622B2 (ja) | 2014-07-21 | 2022-04-14 | ノバルティス アーゲー | ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置 |
| EP3172231B1 (en) | 2014-07-24 | 2021-05-05 | Bluebird Bio, Inc. | Bcma chimeric antigen receptors |
| EP3227432B1 (en) | 2014-12-05 | 2023-10-11 | Memorial Sloan Kettering Cancer Center | Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof |
| KR102701479B1 (ko) | 2014-12-05 | 2024-09-03 | 메모리얼 슬로안 케터링 캔서 센터 | B-세포 성숙화 항원을 표적화하는 항체 및 사용 방법 |
| LT3230321T (lt) | 2014-12-12 | 2019-12-10 | Bluebird Bio Inc | Bcma chimeriniai antigeno receptoriai |
| EP3256492A4 (en) * | 2015-02-09 | 2018-07-11 | University of Florida Research Foundation, Inc. | Bi-specific chimeric antigen receptor and uses thereof |
| EP3259352A4 (en) | 2015-02-19 | 2018-12-05 | University of Florida Research Foundation, Inc. | Chimeric antigen receptors and uses thereof |
| SG11201707089WA (en) | 2015-04-13 | 2017-10-30 | Pfizer | Chimeric antigen receptors targeting b-cell maturation antigen |
| DK3298033T4 (da) | 2015-05-18 | 2023-10-02 | Tcr2 Therapeutics Inc | Sammensætninger og medicinske anvendelser til tcr-reprogrammering under anvendelse af fusionsproteiner |
| CN106397592A (zh) * | 2015-07-31 | 2017-02-15 | 苏州康宁杰瑞生物科技有限公司 | 针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白 |
| CN105384825B (zh) | 2015-08-11 | 2018-06-01 | 南京传奇生物科技有限公司 | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 |
| MA45426A (fr) | 2015-10-22 | 2019-05-01 | Juno Therapeutics Gmbh | Procédés, kits, agents et appareils de transduction |
| US11479755B2 (en) | 2015-12-07 | 2022-10-25 | 2Seventy Bio, Inc. | T cell compositions |
| CN109072195A (zh) | 2015-12-30 | 2018-12-21 | 诺华股份有限公司 | 具有增强功效的免疫效应细胞疗法 |
| WO2017130223A2 (en) | 2016-01-29 | 2017-08-03 | Virocan Therapeutics Pvt. Ltd. | A chimeric antigen receptor specific to b-cell maturation antigen, a recombinant expression vector and a method thereof |
| KR20180118175A (ko) | 2016-03-04 | 2018-10-30 | 노파르티스 아게 | 다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도 |
| EP4286522A3 (en) * | 2016-03-23 | 2024-02-28 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins of pd-1 and 4-1bb |
| US11549099B2 (en) | 2016-03-23 | 2023-01-10 | Novartis Ag | Cell secreted minibodies and uses thereof |
| AR108067A1 (es) * | 2016-04-01 | 2018-07-11 | Kite Pharma Inc | Moléculas de unión y métodos de uso de los mismos |
| CA3177398A1 (en) | 2016-04-01 | 2017-10-05 | Kite Pharma, Inc. | Chimeric receptors and methods of use thereof |
| CN109328074A (zh) | 2016-04-01 | 2019-02-12 | 凯德药业股份有限公司 | 嵌合抗原和t细胞受体及使用的方法 |
| JP2019510503A (ja) * | 2016-04-07 | 2019-04-18 | ブルーバード バイオ, インコーポレイテッド | キメラ抗原受容体t細胞組成物 |
| JP7125351B2 (ja) | 2016-04-14 | 2022-08-24 | 2セブンティ バイオ インコーポレイテッド | サルベージキメラ抗原受容体システム |
| PL3443096T3 (pl) | 2016-04-15 | 2023-06-19 | Novartis Ag | Kompozycje i sposoby do selektywnej ekspresji chimerycznych receptorów antygenowych |
| US11634498B2 (en) | 2016-04-29 | 2023-04-25 | University Of Florida Research Foundation, Incorporated | Chimeric antigen receptors and uses thereof |
| AU2017276706B2 (en) | 2016-06-07 | 2024-08-15 | Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft | Chimeric antigen receptor and CAR-T cells that bind BCMA |
| JP2019527696A (ja) | 2016-08-01 | 2019-10-03 | ノバルティス アーゲー | プロm2マクロファージ分子の阻害剤と組み合わせてキメラ抗原受容体を用いる癌の処置 |
| JP7109789B2 (ja) * | 2016-08-02 | 2022-08-01 | ティーシーアール2 セラピューティクス インク. | 融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法 |
| EP3500696A4 (en) | 2016-08-16 | 2020-04-08 | Bluebird Bio, Inc. | VARIANTS OF IL-10 ALPHA RECEPTOR HOMING ENDONUCLEASE, COMPOSITIONS AND METHODS OF USE |
| WO2018064626A1 (en) * | 2016-09-30 | 2018-04-05 | Baylor College Of Medicine | Adaptive chimeric antigen receptor t-cell design |
| CA3036745A1 (en) | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
| AU2017355504C1 (en) | 2016-11-04 | 2024-06-20 | 2Seventy Bio, Inc. | Anti-BCMA CAR T cell compositions |
| CA3044593A1 (en) | 2016-11-22 | 2018-05-31 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| CN110177544A (zh) | 2016-11-29 | 2019-08-27 | 普尔泰克健康有限公司 | 用于递送治疗剂的外泌体 |
| KR20190098747A (ko) * | 2016-12-05 | 2019-08-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 치료법을 위한 조작된 세포의 제조방법 |
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2015
- 2015-07-23 EP EP15824299.0A patent/EP3172231B1/en active Active
- 2015-07-23 SG SG10201900455YA patent/SG10201900455YA/en unknown
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- 2015-07-23 ES ES15824299T patent/ES2878449T3/es active Active
- 2015-07-23 RU RU2017106025A patent/RU2747457C2/ru active
- 2015-07-23 SG SG11201700492SA patent/SG11201700492SA/en unknown
- 2015-07-23 KR KR1020177005065A patent/KR102523934B1/ko active Active
- 2015-07-23 WO PCT/US2015/041722 patent/WO2016014789A2/en not_active Ceased
- 2015-07-23 US US15/328,278 patent/US20170226216A1/en not_active Abandoned
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2019
- 2019-07-18 US US16/515,870 patent/US12006369B2/en active Active
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2024
- 2024-05-15 US US18/664,795 patent/US20240417481A1/en active Pending
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