|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
IL47062A
(en)
|
1975-04-10 |
1979-07-25 |
Yeda Res & Dev |
Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
|
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
|
FR2413974A1
(fr)
|
1978-01-06 |
1979-08-03 |
David Bernard |
Sechoir pour feuilles imprimees par serigraphie
|
|
US4256833A
(en)
|
1979-01-08 |
1981-03-17 |
Majid Ali |
Enzyme immunoassay for allergic disorders
|
|
US4665077A
(en)
|
1979-03-19 |
1987-05-12 |
The Upjohn Company |
Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4671958A
(en)
|
1982-03-09 |
1987-06-09 |
Cytogen Corporation |
Antibody conjugates for the delivery of compounds to target sites
|
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
DD266710A3
(de)
|
1983-06-06 |
1989-04-12 |
Ve Forschungszentrum Biotechnologie |
Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
|
US4879231A
(en)
|
1984-10-30 |
1989-11-07 |
Phillips Petroleum Company |
Transformation of yeasts of the genus pichia
|
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
US5204244A
(en)
|
1987-10-27 |
1993-04-20 |
Oncogen |
Production of chimeric antibodies by homologous recombination
|
|
IL85746A
(en)
|
1988-03-15 |
1994-05-30 |
Yeda Res & Dev |
Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases
|
|
FI891226L
(fi)
|
1988-04-28 |
1989-10-29 |
Univ Leland Stanford Junior |
Reseptordeterminanter i anti-t-celler foer behandling av autoimmunsjukdom.
|
|
WO1990003430A1
(en)
|
1988-09-23 |
1990-04-05 |
Cetus Corporation |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
WO1990008187A1
(en)
|
1989-01-19 |
1990-07-26 |
Dana Farber Cancer Institute |
Soluble two domain cd2 protein
|
|
CA2046909A1
(en)
|
1989-03-21 |
1990-09-22 |
Mark D. Howell |
Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
|
|
EP0402226A1
(en)
|
1989-06-06 |
1990-12-12 |
Institut National De La Recherche Agronomique |
Transformation vectors for yeast yarrowia
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
EP0739904A1
(en)
|
1989-06-29 |
1996-10-30 |
Medarex, Inc. |
Bispecific reagents for aids therapy
|
|
JP3072330B2
(ja)
|
1989-07-19 |
2000-07-31 |
ジ・イミューン・レスポンス・コーポレーション |
自己免疫疾患および悪性疾患の治療のためのｔ細胞リセプターペプチド
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
WO1992020373A1
(en)
|
1991-05-14 |
1992-11-26 |
Repligen Corporation |
Heteroconjugate antibodies for treatment of hiv infection
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
DE69233528T2
(de)
|
1991-11-25 |
2006-03-16 |
Enzon, Inc. |
Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
|
|
CA2372813A1
(en)
|
1992-02-06 |
1993-08-19 |
L.L. Houston |
Biosynthetic binding protein for cancer marker
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
DE69308573T2
(de)
|
1992-08-17 |
1997-08-07 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
US5534615A
(en)
|
1994-04-25 |
1996-07-09 |
Genentech, Inc. |
Cardiac hypertrophy factor and uses therefor
|
|
US6214388B1
(en)
|
1994-11-09 |
2001-04-10 |
The Regents Of The University Of California |
Immunoliposomes that optimize internalization into target cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
|
DE19544393A1
(de)
|
1995-11-15 |
1997-05-22 |
Hoechst Schering Agrevo Gmbh |
Synergistische herbizide Mischungen
|
|
US6458939B1
(en)
|
1996-03-15 |
2002-10-01 |
Millennium Pharmaceuticals, Inc. |
Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
|
|
HUP0104865A3
(en)
|
1999-01-15 |
2004-07-28 |
Genentech Inc |
Polypeptide variants with altered effector function
|
|
WO2001080884A1
(en)
|
2000-04-25 |
2001-11-01 |
Idec Pharmaceuticals Corporation |
Intrathecal administration of rituximab for treatment of central nervous system lymphomas
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
WO2005009339A2
(en)
*
|
2003-05-30 |
2005-02-03 |
Pathway Diagnostics Corporation, Inc. (a Delaware Corporation) |
Inflammatory bowel diseases
|
|
US20110152115A1
(en)
*
|
2003-09-03 |
2011-06-23 |
The United States of America, as represented by the Secretary, Department of Health and |
Methods for identifying, diagnosing, and predicting survival of lymphomas
|
|
ES2377979T3
(es)
|
2004-09-03 |
2012-04-03 |
Genentech, Inc. |
Antagonistas anti-beta7 humanizados y utilizaciones para los mismos
|
|
WO2006083390A2
(en)
*
|
2004-12-07 |
2006-08-10 |
Children's Hospital Medical Center |
Eotaxin-3 in eosinophilic esophagitis
|
|
CA2628401A1
(en)
*
|
2005-12-07 |
2007-06-14 |
Boehringer Ingelheim International Gmbh |
Treatment and diagnostics of inflammatory diseases
|
|
CN101490085A
(zh)
*
|
2006-06-12 |
2009-07-22 |
特鲁比昂药品公司 |
具有效应功能的单链多价结合蛋白
|
|
US20080293582A1
(en)
*
|
2006-08-30 |
2008-11-27 |
Xilin Li |
Markers and Methods for Assessing and Treating Ulcerative Colitis and Related Disorders Using a 43 Gene Panel
|
|
CA2675583A1
(en)
*
|
2007-01-16 |
2008-07-24 |
Wyeth |
Inflammation treatment, detection and monitoring via trem-1
|
|
MX2009009167A
(es)
*
|
2007-02-28 |
2009-09-04 |
Schering Corp |
Terapia de combinacion para el tratamiento de trastornos inmunes.
|
|
TW200848431A
(en)
*
|
2007-06-12 |
2008-12-16 |
Trubion Pharmaceuticals Inc |
Single-chain multivalent binding proteins with effector function
|
|
KR101620642B1
(ko)
*
|
2007-11-07 |
2016-05-12 |
제넨테크, 인크. |
항-ｃｄ４０ 항체를 사용한 치료에 대한 ｂ-세포 림프종의 반응성 평가를 위한 방법 및 조성물
|
|
HRP20150684T1
(hr)
*
|
2008-02-19 |
2015-09-11 |
The Children's Hospital Of Philadelphia, Abramson Pediatric Research Center, Office of Technology Transfer |
Identifikacija specifiäśnih mjesta nastanka - genetski loci - upalne bolesti crijeva kod djece i postupci njihove uporabe u takvoj dijagnozi te njihovo lijeäśenje
|
|
WO2009120877A2
(en)
*
|
2008-03-26 |
2009-10-01 |
The Johns Hopkins University |
Microrna-based diagnostic testing and therapies for inflammatory bowel disease and related diseases
|
|
WO2009140684A2
(en)
*
|
2008-05-16 |
2009-11-19 |
Genentech, Inc. |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7integrin antagonists
|
|
EP2347256A4
(en)
*
|
2008-10-09 |
2012-02-08 |
Alfagene Bioscience Inc |
USE AND IDENTIFY BIOMARKERS FOR STOMACH DISEASES
|
|
EP2352762A1
(en)
*
|
2008-11-03 |
2011-08-10 |
Schering Corporation |
Inflammatory bowel disease biomarkers and related methods of treatment
|
|
NZ619527A
(en)
*
|
2009-04-14 |
2015-06-26 |
Nestec Sa |
Inflammatory bowel disease prognostics
|
|
US20110033486A1
(en)
*
|
2009-07-20 |
2011-02-10 |
Abbas Alexander R |
Gene expression markers for crohn's disease
|
|
TW201138808A
(en)
*
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
US8766034B2
(en)
*
|
2010-09-22 |
2014-07-01 |
Cedars-Sinai Medical Center |
TL1A model of inflammation fibrosis and autoimmunity
|
|
EP2668287B1
(en)
*
|
2011-01-25 |
2017-09-06 |
TC LAND Expression |
Genes and genes combinations based on gene mknk1 predictive of early response or non response of subjects suffering from rheumatoid arthritis to tnf-alpha blocking monoclonal antibody
|
|
MX2013011130A
(es)
*
|
2011-03-31 |
2013-10-30 |
Genentech Inc |
Metodos de administracion de antagonistas de integrina beta7.
|
|
US20130040835A1
(en)
*
|
2011-05-05 |
2013-02-14 |
Exagen Diagnostics, Inc |
Genes predictive of anti-TNF response in inflammatory diseases
|
|
CN102876794B
(zh)
*
|
2012-09-29 |
2014-07-02 |
山东省皮肤病性病防治研究所 |
单核苷酸多态性rs6871626在检测麻风病易感基因中的应用
|
|
CN102876793B
(zh)
*
|
2012-09-29 |
2014-03-12 |
山东省皮肤病性病防治研究所 |
单核苷酸多态性rs2058660在检测麻风病易感基因中的应用
|
|
KR101850591B1
(ko)
|
2012-10-05 |
2018-04-19 |
제넨테크, 인크. |
염증성 장 질환의 진단 및 치료 방법
|
|
JP6615745B2
(ja)
|
2013-03-27 |
2019-12-04 |
ジェネンテック， インコーポレイテッド |
ベータ７インテグリンアンタゴニストによる胃腸炎症障害の治療を評価するためのバイオマーカーの使用
|
|
JP7054990B2
(ja)
*
|
2014-03-27 |
2022-04-15 |
ジェネンテック， インコーポレイテッド |
炎症性腸疾患の診断及び治療のための方法
|