JP2018526323A5 - - Google Patents

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JP2018526323A5
JP2018526323A5 JP2017561962A JP2017561962A JP2018526323A5 JP 2018526323 A5 JP2018526323 A5 JP 2018526323A5 JP 2017561962 A JP2017561962 A JP 2017561962A JP 2017561962 A JP2017561962 A JP 2017561962A JP 2018526323 A5 JP2018526323 A5 JP 2018526323A5
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methylation
chr9
antibody
medium
levels
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JP2018526323A (ja
JP6884111B2 (ja
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Priority claimed from PCT/US2016/034856 external-priority patent/WO2016196381A1/en
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JP2017561962A 2015-05-29 2016-05-27 癌におけるpd−l1プロモーターのメチル化 Active JP6884111B2 (ja)

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JP2021036418A JP2021102621A (ja) 2015-05-29 2021-03-08 癌におけるpd−l1プロモーターのメチル化

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US201562168668P 2015-05-29 2015-05-29
US62/168,668 2015-05-29
PCT/US2016/034856 WO2016196381A1 (en) 2015-05-29 2016-05-27 Pd-l1 promoter methylation in cancer

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JP2018526323A JP2018526323A (ja) 2018-09-13
JP2018526323A5 true JP2018526323A5 (enExample) 2020-09-10
JP6884111B2 JP6884111B2 (ja) 2021-06-09

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JP2021036418A Pending JP2021102621A (ja) 2015-05-29 2021-03-08 癌におけるpd−l1プロモーターのメチル化

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US (1) US11254987B2 (enExample)
EP (2) EP3303619B1 (enExample)
JP (2) JP6884111B2 (enExample)
KR (1) KR20180013881A (enExample)
CN (1) CN108064170B (enExample)
AR (1) AR105618A1 (enExample)
AU (1) AU2016271142A1 (enExample)
CA (1) CA2984638A1 (enExample)
ES (1) ES2810700T3 (enExample)
HK (1) HK1255200A1 (enExample)
IL (1) IL255375A0 (enExample)
MX (1) MX388405B (enExample)
PL (1) PL3303619T3 (enExample)
WO (1) WO2016196381A1 (enExample)

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CN108112254B (zh) 2015-03-13 2022-01-28 西托姆克斯治疗公司 抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法
MX2018001507A (es) 2015-08-03 2018-09-18 Enb Therapeutics Llc Composiciones y metodos para tratar cánceres asociados con la activacion del etbr.
AR107303A1 (es) 2016-01-08 2018-04-18 Hoffmann La Roche Métodos de tratamiento de cánceres positivos para ace utilizando antagonistas de unión a eje pd-1 y anticuerpos biespecíficos anti-ace / anti-cd3, uso, composición, kit
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BR112019025188A2 (pt) 2017-06-01 2020-06-23 Cytomx Therapeutics, Inc. Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos
US11560431B2 (en) * 2017-06-25 2023-01-24 Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. Anti-PD-L1 antibodies and methods of making and using thereof
CN111886010A (zh) 2018-01-12 2020-11-03 Enb治疗公司 用于治疗与etbr激活相关的癌症的氘化化合物、组合物和方法
KR102708681B1 (ko) 2018-02-13 2024-09-26 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
UA126421C2 (uk) 2018-07-13 2022-09-28 Гіліад Сайєнсіз, Інк. Інгібітори pd-1/pd-l1
CN109355381A (zh) * 2018-09-14 2019-02-19 深圳市太空科技南方研究院 用于预测pd1/l1抑制剂疗效的生物标记物和方法
CN111035758A (zh) * 2018-10-11 2020-04-21 江苏康缘药业股份有限公司 药物组合物及其应用、无菌容器和试剂盒
EP3899019A4 (en) * 2018-12-21 2022-10-05 Agency for Science, Technology and Research METHOD OF PREDICTING THE BENEFITS OF IMMUNE CHECKPOINT INHIBITION THERAPY
WO2021035172A1 (en) * 2019-08-21 2021-02-25 H. Lee Moffitt Cancer Center And Research Institute, Inc. Diagnostics and methods for prognosing response to immunotherapy based on the methylation status of immune synapse gene signature
CN112735513B (zh) * 2021-01-04 2021-11-19 江苏先声医疗器械有限公司 基于dna甲基化谱的肿瘤免疫检查点抑制剂治疗有效性评估模型的构建方法
CN121532528A (zh) * 2023-06-30 2026-02-13 夸登特健康公司 用于癌症早期检测的方法

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