EP3122377A4 - Methods for diagnosing and treating inflammatory bowel disease - Google Patents
Methods for diagnosing and treating inflammatory bowel disease Download PDFInfo
- Publication number
- EP3122377A4 EP3122377A4 EP15768557.9A EP15768557A EP3122377A4 EP 3122377 A4 EP3122377 A4 EP 3122377A4 EP 15768557 A EP15768557 A EP 15768557A EP 3122377 A4 EP3122377 A4 EP 3122377A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diagnosing
- methods
- inflammatory bowel
- bowel disease
- treating inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461971379P | 2014-03-27 | 2014-03-27 | |
PCT/US2015/022762 WO2015148809A1 (en) | 2014-03-27 | 2015-03-26 | Methods for diagnosing and treating inflammatory bowel disease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3122377A1 EP3122377A1 (en) | 2017-02-01 |
EP3122377A4 true EP3122377A4 (en) | 2018-03-14 |
Family
ID=54196399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15768557.9A Pending EP3122377A4 (en) | 2014-03-27 | 2015-03-26 | Methods for diagnosing and treating inflammatory bowel disease |
Country Status (15)
Country | Link |
---|---|
US (4) | US10273542B2 (en) |
EP (1) | EP3122377A4 (en) |
JP (3) | JP7054990B2 (en) |
KR (2) | KR102397324B1 (en) |
CN (2) | CN106102767B (en) |
AR (1) | AR099856A1 (en) |
AU (3) | AU2015235986B2 (en) |
BR (1) | BR112016020053A2 (en) |
CA (1) | CA2939246A1 (en) |
IL (2) | IL247266B (en) |
MA (1) | MA39804A (en) |
MX (2) | MX2016012282A (en) |
RU (1) | RU2016136716A (en) |
SG (1) | SG11201607938UA (en) |
WO (1) | WO2015148809A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2723614C (en) * | 2008-05-16 | 2015-07-14 | Genentech, Inc. | Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists |
RU2016136716A (en) | 2014-03-27 | 2018-04-28 | Дженентек, Инк. | METHODS FOR DIAGNOSTIC AND TREATMENT OF INFLAMMATORY DISEASES OF THE GUT |
EP3978530A1 (en) * | 2015-02-26 | 2022-04-06 | F. Hoffmann-La Roche AG | Integrin beta7 antagonists and methods of treating crohn's disease |
GB201611738D0 (en) * | 2016-07-05 | 2016-08-17 | Cambridge Entpr Ltd | Biomarkers for inflammatory bowel disease |
CN107083423B (en) * | 2017-03-27 | 2022-01-28 | 北京极客基因科技有限公司 | Drug target prediction and drug full-range evaluation method |
MA52249A (en) | 2018-04-12 | 2021-05-05 | Morphic Therapeutic Inc | HUMAN INTEGRIN ANTAGONISTS (ALPHA4) (BETA7) |
US20220364171A1 (en) * | 2018-11-23 | 2022-11-17 | Katholieke Universiteit Leuven | Predicting a treatment response in inflammatory bowel disease |
EP3935581A4 (en) | 2019-03-04 | 2022-11-30 | Iocurrents, Inc. | Data compression and communication using machine learning |
KR20220102669A (en) | 2019-10-16 | 2022-07-20 | 모픽 테라퓨틱, 인코포레이티드 | Inhibition of human integrin α4β7 |
JP2023536158A (en) | 2020-07-31 | 2023-08-23 | ジェネンテック, インコーポレイテッド | Anti-integrin β7 antibody formulation and device |
WO2023061502A1 (en) * | 2021-10-15 | 2023-04-20 | 苏州生物医药转化工程中心 | Bispecific binding molecule |
CN114085908B (en) * | 2021-10-30 | 2023-08-08 | 中国人民解放军陆军军医大学第一附属医院 | Gene target combination for evaluating glioblastoma treatment effect and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009140684A2 (en) * | 2008-05-16 | 2009-11-19 | Genentech, Inc. | Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7integrin antagonists |
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-
2015
- 2015-03-26 RU RU2016136716A patent/RU2016136716A/en not_active Application Discontinuation
- 2015-03-26 CN CN201580016240.3A patent/CN106102767B/en active Active
- 2015-03-26 CA CA2939246A patent/CA2939246A1/en active Pending
- 2015-03-26 SG SG11201607938UA patent/SG11201607938UA/en unknown
- 2015-03-26 CN CN202110901698.4A patent/CN113604543A/en active Pending
- 2015-03-26 EP EP15768557.9A patent/EP3122377A4/en active Pending
- 2015-03-26 MA MA039804A patent/MA39804A/en unknown
- 2015-03-26 BR BR112016020053-5A patent/BR112016020053A2/en not_active Application Discontinuation
- 2015-03-26 WO PCT/US2015/022762 patent/WO2015148809A1/en active Application Filing
- 2015-03-26 AU AU2015235986A patent/AU2015235986B2/en active Active
- 2015-03-26 JP JP2016559188A patent/JP7054990B2/en active Active
- 2015-03-26 KR KR1020167026095A patent/KR102397324B1/en active IP Right Grant
- 2015-03-26 MX MX2016012282A patent/MX2016012282A/en unknown
- 2015-03-26 AR ARP150100901A patent/AR099856A1/en unknown
- 2015-03-26 KR KR1020227015554A patent/KR20220065091A/en not_active Application Discontinuation
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2016
- 2016-08-14 IL IL247266A patent/IL247266B/en active IP Right Grant
- 2016-09-21 US US15/271,687 patent/US10273542B2/en active Active
- 2016-09-22 MX MX2022010809A patent/MX2022010809A/en unknown
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2019
- 2019-03-07 US US16/295,536 patent/US10669587B2/en active Active
- 2019-11-21 JP JP2019210883A patent/JP2020062013A/en not_active Withdrawn
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2020
- 2020-04-10 US US16/845,575 patent/US11261493B2/en active Active
- 2020-08-05 IL IL276516A patent/IL276516A/en unknown
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2021
- 2021-01-28 AU AU2021200518A patent/AU2021200518B2/en active Active
- 2021-05-21 AU AU2021203296A patent/AU2021203296A1/en active Pending
- 2021-11-12 JP JP2021185176A patent/JP2022043033A/en active Pending
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2022
- 2022-01-20 US US17/580,357 patent/US20220186314A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009140684A2 (en) * | 2008-05-16 | 2009-11-19 | Genentech, Inc. | Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7integrin antagonists |
Non-Patent Citations (5)
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