JP7054990B2 - 炎症性腸疾患の診断及び治療のための方法 - Google Patents

炎症性腸疾患の診断及び治療のための方法 Download PDF

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JP7054990B2
JP7054990B2 JP2016559188A JP2016559188A JP7054990B2 JP 7054990 B2 JP7054990 B2 JP 7054990B2 JP 2016559188 A JP2016559188 A JP 2016559188A JP 2016559188 A JP2016559188 A JP 2016559188A JP 7054990 B2 JP7054990 B2 JP 7054990B2
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JP2017511131A (ja
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ジェイソン エー． ハックニー，
メアリー キア，
ガイク ウェイ テュー，
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
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JP2016559188A 2014-03-27 2015-03-26 炎症性腸疾患の診断及び治療のための方法 Expired - Fee Related JP7054990B2 (ja)

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US201461971379P 2014-03-27 2014-03-27
US61/971,379 2014-03-27
PCT/US2015/022762 WO2015148809A1 (en) 2014-03-27 2015-03-26 Methods for diagnosing and treating inflammatory bowel disease

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JP2017511131A JP2017511131A (ja) 2017-04-20
JP2017511131A5 JP2017511131A5 (enExample) 2018-05-10
JP7054990B2 true JP7054990B2 (ja) 2022-04-15

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JP2019210883A Withdrawn JP2020062013A (ja) 2014-03-27 2019-11-21 炎症性腸疾患の診断及び治療のための方法
JP2021185176A Pending JP2022043033A (ja) 2014-03-27 2021-11-12 炎症性腸疾患の診断及び治療のための方法

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JP2021185176A Pending JP2022043033A (ja) 2014-03-27 2021-11-12 炎症性腸疾患の診断及び治療のための方法

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US (4) US10273542B2 (enExample)
EP (1) EP3122377A4 (enExample)
JP (3) JP7054990B2 (enExample)
KR (2) KR20220065091A (enExample)
CN (2) CN106102767B (enExample)
AR (1) AR099856A1 (enExample)
AU (3) AU2015235986B2 (enExample)
BR (1) BR112016020053A2 (enExample)
CA (1) CA2939246A1 (enExample)
IL (2) IL247266B (enExample)
MA (1) MA39804A (enExample)
MX (2) MX2016012282A (enExample)
RU (1) RU2016136716A (enExample)
SG (1) SG11201607938UA (enExample)
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CN106102767B (zh) 2014-03-27 2021-08-10 豪夫迈·罗氏有限公司 用于诊断和治疗炎症性肠病的方法
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CN107083423B (zh) * 2017-03-27 2022-01-28 北京极客基因科技有限公司 一种药物靶点预测和药物全方面评价方法
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JP2022523564A (ja) 2019-03-04 2022-04-25 アイオーカレンツ， インコーポレイテッド 機械学習を使用するデータ圧縮および通信
KR20220088529A (ko) 2019-05-14 2022-06-27 프로메테우스 바이오사이언시즈, 인크. Tl1a 환자 선택 방법, 시스템 및 장치
JP2022541125A (ja) 2019-06-27 2022-09-22 サイファー メディシン コーポレーション 患者を層別化するための分類子の開発
TWI775182B (zh) 2019-10-16 2022-08-21 美商莫菲克醫療股份有限公司 抑制人類整合素αβ
US12394524B2 (en) * 2020-07-22 2025-08-19 Iterative Scopes, Inc. Systems and methods for analysis of medical images for scoring of inflammatory bowel disease
JP2023536158A (ja) 2020-07-31 2023-08-23 ジェネンテック， インコーポレイテッド 抗インテグリンβ７抗体製剤及び装置
KR20240018404A (ko) * 2020-09-01 2024-02-13 사이퍼 메디슨 코퍼레이션 항-tnf 요법에 대한 반응을 예측하기 위한 방법 및 시스템
WO2023061502A1 (zh) * 2021-10-15 2023-04-20 苏州生物医药转化工程中心 一种双特异性结合分子
CN114085908B (zh) * 2021-10-30 2023-08-08 中国人民解放军陆军军医大学第一附属医院 用于评估胶质母细胞瘤治疗效果的基因靶点组合及其应用
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