JP2017501197A5 - - Google Patents

Download PDF

Info

Publication number
JP2017501197A5
JP2017501197A5 JP2016543735A JP2016543735A JP2017501197A5 JP 2017501197 A5 JP2017501197 A5 JP 2017501197A5 JP 2016543735 A JP2016543735 A JP 2016543735A JP 2016543735 A JP2016543735 A JP 2016543735A JP 2017501197 A5 JP2017501197 A5 JP 2017501197A5
Authority
JP
Japan
Prior art keywords
compound
dmf
group
formula
alkylating agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016543735A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017501197A (ja
JP6585057B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/072569 external-priority patent/WO2015103144A1/en
Publication of JP2017501197A publication Critical patent/JP2017501197A/ja
Publication of JP2017501197A5 publication Critical patent/JP2017501197A5/ja
Application granted granted Critical
Publication of JP6585057B2 publication Critical patent/JP6585057B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016543735A 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法 Active JP6585057B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361922582P 2013-12-31 2013-12-31
US201361922572P 2013-12-31 2013-12-31
US61/922,582 2013-12-31
US61/922,572 2013-12-31
PCT/US2014/072569 WO2015103144A1 (en) 2013-12-31 2014-12-29 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019160781A Division JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Publications (3)

Publication Number Publication Date
JP2017501197A JP2017501197A (ja) 2017-01-12
JP2017501197A5 true JP2017501197A5 (https=) 2018-02-15
JP6585057B2 JP6585057B2 (ja) 2019-10-02

Family

ID=53480979

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016543746A Active JP6804297B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法
JP2016543735A Active JP6585057B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法
JP2019160781A Withdrawn JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016543746A Active JP6804297B2 (ja) 2013-12-31 2014-12-29 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019160781A Withdrawn JP2019218396A (ja) 2013-12-31 2019-09-04 ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法

Country Status (24)

Country Link
US (8) US20150183750A1 (https=)
EP (4) EP3862347A1 (https=)
JP (3) JP6804297B2 (https=)
CN (4) CN111217759A (https=)
AP (1) AP2016009342A0 (https=)
AU (2) AU2014373959B2 (https=)
BR (2) BR102014033010B1 (https=)
CA (2) CA2935594C (https=)
CL (1) CL2016001677A1 (https=)
CR (2) CR20160343A (https=)
DO (1) DOP2016000163A (https=)
EA (2) EA036389B1 (https=)
EC (1) ECSP16064249A (https=)
IL (3) IL246512B (https=)
MX (2) MX392211B (https=)
NI (1) NI201600094A (https=)
NZ (2) NZ722438A (https=)
PE (1) PE20161174A1 (https=)
PH (1) PH12016501284A1 (https=)
SG (2) SG11201605372QA (https=)
TW (2) TWI667229B (https=)
UA (2) UA129860C2 (https=)
UY (2) UY35942A (https=)
WO (2) WO2015103144A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2638556C2 (ru) 2012-12-28 2017-12-14 Адама Мактешим Лтд. Производные n-(замещенного)-5-фтор-4-имино-3-метил-2-оксо-3,4-дигидропиримидин-1(2н)-карбоксилата
CA2894510A1 (en) 2012-12-28 2014-07-03 Dow Agrosciences Llc N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxamide derivatives
AU2013370494B2 (en) 2012-12-31 2017-08-17 Adama Makhteshim Ltd. 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides
NZ722419A (en) 2013-12-31 2018-01-26 Adama Makhteshim Ltd Synergistic fungicidal mixtures and compositions for fungal control
CA2935594C (en) 2013-12-31 2022-05-03 Nakyen Choy 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation
UY36964A (es) 2015-10-27 2017-05-31 Bayer Cropscience Ag Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida
JP6922271B2 (ja) * 2016-03-11 2021-08-18 住友化学株式会社 植物病害防除組成物及び植物病害防除方法
EP3655396A1 (en) * 2017-07-17 2020-05-27 Adama Makhteshim Ltd. Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one
EP3876717A1 (en) * 2018-11-05 2021-09-15 Adama Makhteshim Ltd. Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof
IL321760A (en) 2019-07-22 2025-08-01 Adama Makhteshim Ltd Fungicidal combinations, mixtures and compositions and uses thereof
PY2057637A (es) * 2019-09-23 2021-10-05 Adama Makhteshim Ltd Proceso para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto
CN115776980A (zh) * 2020-03-09 2023-03-10 阿达玛马克西姆有限公司 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法
EP4146632A1 (en) * 2020-05-04 2023-03-15 Adama Makhteshim Ltd. Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof
CA3185119A1 (en) 2020-07-08 2022-01-13 Matteo CERNUSCHI Fungicidal mixtures
BR112023014997A2 (pt) 2021-01-27 2023-10-03 Adama Makhteshim Ltd 5-fluoro-4-imino-3-metil-1-tosil-3,4-di-hidropirimidin-2(1h)-ona para controle de doenças de plantas
US20240237649A1 (en) 2021-05-04 2024-07-18 Adama Makhteshim Ltd. Crystalline forms of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and mixtures, compositions and methods of use thereof
CN118139845A (zh) 2021-09-15 2024-06-04 安道麦马克西姆有限公司 用于制备5-氟-4-亚氨基-3-甲基-1-(甲苯-4-磺酰基)-3,4-二氢-1h-嘧啶-2-酮的方法
UY40172A (es) 2022-03-03 2023-10-13 Adama Makhteshim Ltd Combinaciones, mezclas y composiciones fungicidas y usos de las mismas
EP4609713A3 (en) 2022-05-26 2025-10-29 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
AU2023318916A1 (en) 2022-08-03 2025-02-20 Adama Makhteshim Ltd. 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1h)-one for fungicide-resistant fungus
AU2024233301A1 (en) 2023-03-09 2025-09-18 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
AU2024236967A1 (en) 2023-03-14 2025-09-25 Adama Makhteshim Ltd. Liquid compositions containing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1h)-one and derivatives thereof and a uv absorber
WO2024194833A1 (en) * 2023-03-23 2024-09-26 Adama Makhteshim Ltd. Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one
WO2025046581A1 (en) 2023-08-31 2025-03-06 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereo
IL308593A (en) 2023-11-15 2025-06-01 Adama Makhteshim Ltd Reducing environmental impact of fungicidal enhancement
PY24105707A (es) 2023-11-28 2025-06-25 Adama Makhteshim Ltd Combinaciones, mezclas y composiciones fungicidas y usos de las mismas
WO2025203024A1 (en) 2024-03-26 2025-10-02 Adama Makhteshim Ltd. Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one
WO2026038217A1 (en) 2024-08-15 2026-02-19 Adama Makhteshim Ltd. Mixtures and compositions comprising flumetylsulforim and methods of use thereof

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309359A (en) 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3368938A (en) 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine
US3635977A (en) 1969-11-03 1972-01-18 American Cyanamid Co Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil
US3868373A (en) 1970-01-27 1975-02-25 Hoffmann La Roche 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines
US4009272A (en) 1971-10-23 1977-02-22 Bayer Aktiengesellschaft Penicillins
CH579057A5 (https=) 1973-09-07 1976-08-31 Hoffmann La Roche
JPS601793B2 (ja) 1979-12-06 1985-01-17 松下電器産業株式会社 カラ−テレビジョン受像機の画質改善装置
FR2530636A1 (fr) 1982-07-23 1984-01-27 Rhone Poulenc Agrochimie Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides
GR80171B (en) 1983-08-29 1985-01-02 Ciba Geigy Ag N-(2-nitrophenyl)-4-aminopyrimidine derivatives process for the preparation thereof and use
US4845081A (en) 1984-10-18 1989-07-04 University Of Florida Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes
EP0230922A2 (de) 1986-01-21 1987-08-05 Boehringer Ingelheim Kg Verwendung von Peptiden zur Herstellung von Mitteln zur Behandlung von Coronarerkrankungen oder organischem Hirnsyndrom
EP0332579B1 (de) 1988-03-09 1994-08-10 Ciba-Geigy Ag Mittel zum Schutz von Pflanzen gegen Krankheiten
DE3821711A1 (de) 1988-06-28 1990-02-08 Bayer Ag Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
US5118816A (en) * 1990-12-26 1992-06-02 American Cyanamid Company 2-aryl-5-(trifluoromethyl)-2-pyrroline compounds useful in the manufacture of insecticidal, nematocidal and acaricidal arylpyrroles
JP3109012B2 (ja) 1992-06-18 2000-11-13 クミアイ化学工業株式会社 チアゾロ［５，４−ｄ］ピリミジン誘導体及び農園芸用殺菌剤
JP3217191B2 (ja) 1992-07-16 2001-10-09 ビーエーエスエフ アクチェンゲゼルシャフト ヘテロ芳香族化合物およびこれを含有する植物保護剤
BR9609613A (pt) 1995-07-05 1999-05-25 Du Pont Composto composição fungicida e método de controle de doenças de plantas
ATE216999T1 (de) 1996-03-11 2002-05-15 Syngenta Participations Ag Pyrimidin-4-on derivate als pestizidesmittel
HRP970239B1 (en) * 1997-05-09 2004-04-30 Inst Ru Er Bouekovic Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity
GT199900185A (es) 1998-11-06 2001-04-18 Novedosa pirimidin-4-enamina como fungicida.
AU1201502A (en) 2000-10-13 2002-04-22 Shire Biochem Inc Dioxolane analogs for improved inter-cellular delivery
US7914799B2 (en) 2001-08-27 2011-03-29 Immunitor USA, Inc. Anti-fungal composition
US20080269238A1 (en) 2004-04-01 2008-10-30 Takeda Pharmaceutical Company Limited Thiazolopyrimidine Derivative
CN101312649B (zh) 2005-11-22 2012-03-28 石原产业株式会社 农业园艺用杀菌剂组合物以及植物病害的防除方法
WO2008005303A2 (en) 2006-06-30 2008-01-10 Janssen Pharmaceutica N.V. Thiazolopyrimidine modulators of trpv1
US20100029483A1 (en) 2006-10-16 2010-02-04 Rhodia Inc. Agricultural adjuvant compositions, pesticide compositions, and methods for using such compositions
EP2077338B1 (en) 2006-10-20 2015-04-01 Nippon Steel & Sumitomo Metal Corporation Nickel material for chemical plant
WO2008083465A1 (en) 2007-01-08 2008-07-17 University Health Network Pyrimidine derivatives as anticancer agents
PT2562166E (pt) 2008-01-22 2015-10-28 Dow Agrosciences Llc Derivados de 5-fluoro-pirimidina como fungicidas
CN102215691B (zh) 2008-08-01 2015-02-04 陶氏益农公司 5-氟胞嘧啶作为杀真菌剂的用途
JP5550151B2 (ja) 2008-09-17 2014-07-16 エスアールアイ インターナショナル インドール−３−カルビノール類似体およびその感染に対する薬剤としての使用
WO2010085377A2 (en) 2009-01-23 2010-07-29 Crystal Biopharmaceutical Llc Hydroxamic acid derivatives
BR112012002807B1 (pt) 2009-08-07 2018-07-10 Adama Makhteshim Ltd. Derivados de 5-flúor-2-oxopirimidina-1(2h)- caboxilato, composição e processo para controle e prevenção de ataque fúngico em uma planta de ataque fúngico em uma planta
UA106889C2 (uk) 2009-08-07 2014-10-27 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні n1-ацил-5-фторпіримідинону
ES2471371T3 (es) 2009-08-07 2014-06-26 Dow Agrosciences Llc Derivados de N1-sulfonil-5-fluoropirimidinona
UA112284C2 (uk) * 2009-08-07 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні 5-фторпіримідинону
UA107671C2 (en) 2009-08-07 2015-02-10 Dow Agrosciences Llc N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives
NZ599124A (en) 2009-10-07 2014-03-28 Dow Agrosciences Llc Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals
PH12012502138B1 (en) * 2010-04-26 2019-09-25 Adama Makhteshim Ltd N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives
WO2013025795A1 (en) * 2011-08-17 2013-02-21 Dow Agrosciences Llc 5-fluoro-4-imino-3-(substituted)-3,4-dihydropyrimidin-2-(1h)-one derivatives
US9385377B2 (en) 2012-11-07 2016-07-05 Toyota Jidosha Kabushiki Kaisha Method for producing a catalyst for fuel cells
CA2894510A1 (en) 2012-12-28 2014-07-03 Dow Agrosciences Llc N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2h)-carboxamide derivatives
RU2638556C2 (ru) 2012-12-28 2017-12-14 Адама Мактешим Лтд. Производные n-(замещенного)-5-фтор-4-имино-3-метил-2-оксо-3,4-дигидропиримидин-1(2н)-карбоксилата
MX2015008443A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de 1-(benzoilo-sustituido) -5-fluoro-4-imino-3-metil-3, 4-dihidropirimidin-2 (1h)-ona.
AU2013370494B2 (en) * 2012-12-31 2017-08-17 Adama Makhteshim Ltd. 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides
CA2935594C (en) 2013-12-31 2022-05-03 Nakyen Choy 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation
NZ722419A (en) 2013-12-31 2018-01-26 Adama Makhteshim Ltd Synergistic fungicidal mixtures and compositions for fungal control
MA41272A (fr) 2014-12-23 2017-10-31 Adama Makhteshim Ltd 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences

Similar Documents

Publication Publication Date Title
JP2017501197A5 (https=)
JP2018193405A5 (https=)
JP2017502963A5 (https=)
JP2016518328A5 (https=)
JP2018024670A5 (https=)
JP2016516699A5 (https=)
JP2017514910A5 (https=)
JP2015536898A5 (https=)
JP2015057437A5 (https=)
JP2016503799A5 (https=)
JP2017122107A5 (https=)
JP2018520455A5 (https=)
JP2017505801A5 (https=)
EA201790343A1 (ru) Способ получения сульфамидных производных пиримидина
JP2017538712A5 (https=)
JP2014520901A5 (https=)
JP2015524407A5 (https=)
JP2013525265A5 (https=)
EA019521B1 (ru) Способ получения производных пиперазина
JP2015534542A5 (https=)
JP2014507386A5 (https=)
JP2013517320A5 (https=)
JP2016510719A5 (https=)
JP2014167003A5 (https=)
JP2017226652A5 (https=)