JP2016531108A5 - - Google Patents
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- Publication number
- JP2016531108A5 JP2016531108A5 JP2016528587A JP2016528587A JP2016531108A5 JP 2016531108 A5 JP2016531108 A5 JP 2016531108A5 JP 2016528587 A JP2016528587 A JP 2016528587A JP 2016528587 A JP2016528587 A JP 2016528587A JP 2016531108 A5 JP2016531108 A5 JP 2016531108A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- branched
- linear
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1357277A FR3008978A1 (fr) | 2013-07-23 | 2013-07-23 | "nouveaux derives d'indole et de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent" |
| FR13/57277 | 2013-07-23 | ||
| PCT/FR2014/051884 WO2015011396A1 (fr) | 2013-07-23 | 2014-07-22 | Nouveaux derives d'indole et de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531108A JP2016531108A (ja) | 2016-10-06 |
| JP2016531108A5 true JP2016531108A5 (enExample) | 2017-08-24 |
| JP6458028B2 JP6458028B2 (ja) | 2019-01-23 |
Family
ID=49911607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528587A Expired - Fee Related JP6458028B2 (ja) | 2013-07-23 | 2014-07-22 | インドール及びピロールの新規な誘導体、その製造方法及びそれを含む医薬組成物 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US9765056B2 (enExample) |
| EP (2) | EP3027602B1 (enExample) |
| JP (1) | JP6458028B2 (enExample) |
| KR (1) | KR102337149B1 (enExample) |
| CN (1) | CN105408321B (enExample) |
| AR (1) | AR099914A1 (enExample) |
| AU (1) | AU2014294866B2 (enExample) |
| BR (1) | BR112016001333B1 (enExample) |
| CA (1) | CA2917965C (enExample) |
| CY (1) | CY1120475T1 (enExample) |
| DK (1) | DK3027602T3 (enExample) |
| EA (1) | EA028609B1 (enExample) |
| ES (1) | ES2687475T3 (enExample) |
| FR (1) | FR3008978A1 (enExample) |
| HK (1) | HK1218753A1 (enExample) |
| HR (1) | HRP20181333T1 (enExample) |
| HU (1) | HUE039507T2 (enExample) |
| LT (1) | LT3027602T (enExample) |
| MX (1) | MX364479B (enExample) |
| NZ (1) | NZ715847A (enExample) |
| PL (1) | PL3027602T3 (enExample) |
| PT (1) | PT3027602T (enExample) |
| RS (1) | RS57545B1 (enExample) |
| RU (1) | RU2693404C2 (enExample) |
| SG (1) | SG11201600004SA (enExample) |
| SI (1) | SI3027602T1 (enExample) |
| TW (1) | TW201504224A (enExample) |
| UA (1) | UA117020C2 (enExample) |
| UY (1) | UY35653A (enExample) |
| WO (1) | WO2015011396A1 (enExample) |
| ZA (1) | ZA201600415B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105237509A (zh) * | 2015-11-20 | 2016-01-13 | 江苏瑞邦农药厂有限公司 | 一种2,2-二氟-1,3-苯并二恶茂的合成方法 |
| CN121974842A (zh) | 2016-05-10 | 2026-05-05 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| JP6928096B2 (ja) | 2017-01-10 | 2021-09-01 | イーティーエイチ・チューリッヒ | 細胞保護化合物及びそれらの使用 |
| WO2018181866A1 (ja) | 2017-03-31 | 2018-10-04 | 国立大学法人東京大学 | ノロウイルス抗体 |
| EP4717317A3 (en) | 2017-06-20 | 2026-06-03 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| CN108409580A (zh) * | 2018-02-01 | 2018-08-17 | 浙江工业大学 | 一种苄胺类化合物的合成方法 |
| EP3897631A4 (en) | 2018-12-20 | 2022-11-23 | C4 Therapeutics, Inc. | TARGETED PROTEIN BREAKDOWN |
| KR20230160303A (ko) * | 2021-03-24 | 2023-11-23 | 르 라보레또레 쎄르비에르 | ５－｛５－클로로－２－[(3s)－３－[(모르폴린－４－일)메틸]－３,４－디하이드로이소퀴놀린－２(１ｈ)－카르보닐]페닐｝－１,２－디메틸－１ｈ－피롤－３－카르복실산 유도체의 신규한 합성 방법 및 약학적 화합물의 생산을 위한 이의 용도 |
| IL317101A (en) | 2022-05-20 | 2025-01-01 | Novartis Ag | Antibody-drug conjugates of anticancer compounds and methods of using them |
| AR134424A1 (es) | 2023-11-22 | 2026-01-14 | Novartis Ag | Conjugados de anticuerpo anti-cd7-fármaco y métodos de uso de los mismos |
| UY40985A (es) | 2023-11-22 | 2025-06-30 | Servier Lab | Conjugados de anticuerpo anti-cd74-fármaco y métodos de uso de los mismos |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1675832B1 (en) | 2003-10-24 | 2008-02-20 | Glaxo Group Limited | Heterocyclyl compounds |
| TW200533398A (en) * | 2004-03-29 | 2005-10-16 | Bristol Myers Squibb Co | Novel therapeutic agents for the treatment of migraine |
| BRPI0514504A (pt) * | 2004-08-20 | 2008-06-10 | Univ Michigan | pequenas moléculas inibidoras de membros da famìlia bcl-2 anti-apoptóticos e os usos das mesmas |
| GB0522908D0 (en) | 2005-11-10 | 2005-12-21 | Merck Sharp & Dohme | Therapeutic agents |
| CN103732589B (zh) * | 2011-05-25 | 2016-03-30 | 百时美施贵宝公司 | 可用作抗细胞凋亡bcl抑制剂的取代的磺酰胺 |
| CA2859873A1 (en) * | 2011-12-23 | 2013-06-27 | Novartis Ag | Compounds for inhibiting the interaction of bcl2 with binding partners |
| AU2012355613A1 (en) * | 2011-12-23 | 2014-07-17 | Novartis Ag | Compounds for inhibiting the interaction of BCL2 with binding partners |
| EA201491265A1 (ru) * | 2011-12-23 | 2014-11-28 | Новартис Аг | Соединения для ингибирования взаимодействия bcl-2 с партнерами по связыванию |
| AU2012355623A1 (en) * | 2011-12-23 | 2014-07-17 | Novartis Ag | Compounds for inhibiting the interaction of BCL2 with binding partners |
| AU2012355624A1 (en) * | 2011-12-23 | 2014-07-17 | Novartis Ag | Compounds for inhibiting the interaction of BCL2 with binding partners |
| FR2986002B1 (fr) * | 2012-01-24 | 2014-02-21 | Servier Lab | Nouveaux derives d'indolizine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2013
- 2013-07-23 FR FR1357277A patent/FR3008978A1/fr not_active Withdrawn
-
2014
- 2014-07-08 UY UY35653A patent/UY35653A/es unknown
- 2014-07-21 AR ARP140102679A patent/AR099914A1/es unknown
- 2014-07-22 PL PL14758604T patent/PL3027602T3/pl unknown
- 2014-07-22 RU RU2016106002A patent/RU2693404C2/ru active
- 2014-07-22 HU HUE14758604A patent/HUE039507T2/hu unknown
- 2014-07-22 JP JP2016528587A patent/JP6458028B2/ja not_active Expired - Fee Related
- 2014-07-22 SI SI201430784T patent/SI3027602T1/en unknown
- 2014-07-22 WO PCT/FR2014/051884 patent/WO2015011396A1/fr not_active Ceased
- 2014-07-22 CN CN201480041559.7A patent/CN105408321B/zh not_active Expired - Fee Related
- 2014-07-22 LT LTEP14758604.4T patent/LT3027602T/lt unknown
- 2014-07-22 NZ NZ715847A patent/NZ715847A/en not_active IP Right Cessation
- 2014-07-22 ES ES14758604.4T patent/ES2687475T3/es active Active
- 2014-07-22 SG SG11201600004SA patent/SG11201600004SA/en unknown
- 2014-07-22 EA EA201600121A patent/EA028609B1/ru unknown
- 2014-07-22 US US14/905,877 patent/US9765056B2/en not_active Expired - Fee Related
- 2014-07-22 PT PT147586044T patent/PT3027602T/pt unknown
- 2014-07-22 BR BR112016001333-6A patent/BR112016001333B1/pt not_active IP Right Cessation
- 2014-07-22 DK DK14758604.4T patent/DK3027602T3/en active
- 2014-07-22 MX MX2016000900A patent/MX364479B/es active IP Right Grant
- 2014-07-22 TW TW103125162A patent/TW201504224A/zh unknown
- 2014-07-22 UA UAA201601398A patent/UA117020C2/uk unknown
- 2014-07-22 HK HK16106759.0A patent/HK1218753A1/zh unknown
- 2014-07-22 RS RS20180839A patent/RS57545B1/sr unknown
- 2014-07-22 AU AU2014294866A patent/AU2014294866B2/en not_active Ceased
- 2014-07-22 HR HRP20181333TT patent/HRP20181333T1/hr unknown
- 2014-07-22 KR KR1020167004577A patent/KR102337149B1/ko not_active Expired - Fee Related
- 2014-07-22 CA CA2917965A patent/CA2917965C/fr active Active
- 2014-07-22 EP EP14758604.4A patent/EP3027602B1/fr active Active
- 2014-07-22 EP EP16201228.0A patent/EP3168217A1/fr not_active Withdrawn
-
2016
- 2016-01-12 ZA ZA2016/00415A patent/ZA201600415B/en unknown
-
2017
- 2017-08-14 US US15/676,154 patent/US10662173B2/en active Active
-
2018
- 2018-07-19 CY CY20181100757T patent/CY1120475T1/el unknown
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