JP2016513669A5 - - Google Patents
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- JP2016513669A5 JP2016513669A5 JP2016502268A JP2016502268A JP2016513669A5 JP 2016513669 A5 JP2016513669 A5 JP 2016513669A5 JP 2016502268 A JP2016502268 A JP 2016502268A JP 2016502268 A JP2016502268 A JP 2016502268A JP 2016513669 A5 JP2016513669 A5 JP 2016513669A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- seq
- cys
- gly
- protein according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361780914P | 2013-03-13 | 2013-03-13 | |
| US61/780,914 | 2013-03-13 | ||
| PCT/US2014/026872 WO2014160507A1 (en) | 2013-03-13 | 2014-03-13 | Fusion proteins comprising pdgf and vegf binding portions and methods of using thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019017599A Division JP2019123711A (ja) | 2013-03-13 | 2019-02-04 | Ｐｄｇｆおよびｖｅｇｆ結合部分を含む融合タンパク質ならびにその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513669A JP2016513669A (ja) | 2016-05-16 |
| JP2016513669A5 true JP2016513669A5 (enExample) | 2017-03-30 |
| JP6561042B2 JP6561042B2 (ja) | 2019-08-14 |
Family
ID=50680144
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502268A Active JP6561042B2 (ja) | 2013-03-13 | 2014-03-13 | Ｐｄｇｆおよびｖｅｇｆ結合部分を含む融合タンパク質ならびにその使用方法 |
| JP2019017599A Pending JP2019123711A (ja) | 2013-03-13 | 2019-02-04 | Ｐｄｇｆおよびｖｅｇｆ結合部分を含む融合タンパク質ならびにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019017599A Pending JP2019123711A (ja) | 2013-03-13 | 2019-02-04 | Ｐｄｇｆおよびｖｅｇｆ結合部分を含む融合タンパク質ならびにその使用方法 |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US9637534B2 (enExample) |
| EP (1) | EP2968461B1 (enExample) |
| JP (2) | JP6561042B2 (enExample) |
| KR (1) | KR102228921B1 (enExample) |
| CN (1) | CN105188733B (enExample) |
| AR (1) | AR095437A1 (enExample) |
| AU (2) | AU2014243712B2 (enExample) |
| BR (1) | BR112015022208A8 (enExample) |
| CA (1) | CA2904623A1 (enExample) |
| DK (1) | DK2968461T3 (enExample) |
| ES (1) | ES2933558T3 (enExample) |
| FI (1) | FI2968461T3 (enExample) |
| HR (1) | HRP20221447T1 (enExample) |
| HU (1) | HUE060464T2 (enExample) |
| IL (2) | IL240950B (enExample) |
| LT (1) | LT2968461T (enExample) |
| MX (1) | MX363533B (enExample) |
| PL (1) | PL2968461T3 (enExample) |
| PT (1) | PT2968461T (enExample) |
| RS (1) | RS63820B1 (enExample) |
| RU (1) | RU2692652C2 (enExample) |
| SG (3) | SG11201506802SA (enExample) |
| SI (1) | SI2968461T1 (enExample) |
| TW (1) | TWI631133B (enExample) |
| UY (1) | UY35407A (enExample) |
| WO (1) | WO2014160507A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| HUE060464T2 (hu) | 2013-03-13 | 2023-03-28 | Genzyme Corp | PDGF- és VEGF-kötõrészeket tartalmazó fúziós fehérjék és eljárások azok alkalmazására |
| EP3010525A1 (en) * | 2013-06-20 | 2016-04-27 | Novartis AG | Use of a vegf antagonist in treating choroidal neovascularisation |
| JP6463361B2 (ja) | 2013-09-08 | 2019-01-30 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | 第ｖｉｉｉ因子両性イオンポリマーコンジュゲート |
| KR101844596B1 (ko) | 2014-03-18 | 2018-04-05 | 한국과학기술원 | 당화 vegf 디코이 수용체 융합 단백질을 포함하는 안질환 치료용 조성물 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2015200905A2 (en) * | 2014-06-28 | 2015-12-30 | Oligasis, Llc | Dual pdgf/vegf antagonists |
| JP6849590B2 (ja) | 2014-10-17 | 2021-03-24 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート |
| US11299531B2 (en) | 2015-03-11 | 2022-04-12 | Allgenesis Biotherapeutics Inc. | Fusion protein comprising a ligand binding domain of VEGF and PDGF |
| WO2017001990A1 (en) | 2015-06-28 | 2017-01-05 | Allgenesis Biotherapeutics Inc. | Fusion proteins for inhibiting angiogenesis |
| EP3377101A4 (en) * | 2015-11-19 | 2019-08-07 | Zhuhai Tairuishang Biopharm Ltd. | VEGF BINDING METHODS AND COMPOSITIONS |
| WO2017117464A1 (en) | 2015-12-30 | 2017-07-06 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| WO2017172853A1 (en) | 2016-03-30 | 2017-10-05 | Ab Biosciences, Inc. | Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use |
| KR101685532B1 (ko) * | 2016-04-26 | 2016-12-13 | 한국프라임제약주식회사 | 혈관내피성장인자 수용체 융합단백질 |
| JP6849390B2 (ja) * | 2016-10-28 | 2021-03-24 | 花王株式会社 | 関節のこわばり改善剤 |
| CN111601884A (zh) * | 2017-10-16 | 2020-08-28 | 维格内罗有限责任公司 | Aav载体 |
| KR102205830B1 (ko) * | 2017-10-26 | 2021-01-21 | 주식회사 큐로진생명과학 | 솔루블 VEGFR-1 변이체 cDNA를 함유하는 rAAV를 포함하는 황반변성 치료용 조성물 |
| WO2019083171A2 (ko) * | 2017-10-26 | 2019-05-02 | 주식회사 큐로진생명과학 | 솔루블 vegfr-1 변이체 cdna를 함유하는 raav를 포함하는 황반변성 치료용 조성물 |
| WO2019096226A1 (en) * | 2017-11-16 | 2019-05-23 | Chengdu Easton Biopharmaceuticals Co., Ltd. | Pasylated vegfr/pdgfr fusion proteins and their use in therapy |
| CN111406071B (zh) * | 2017-11-16 | 2024-01-16 | 成都硕德药业有限公司 | Pas化的vegfr/pdgfr融合蛋白及其在治疗中的用途 |
| US11524053B2 (en) * | 2018-01-26 | 2022-12-13 | The Regents Of The University Of California | Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents |
| BR112020017872A2 (pt) | 2018-03-02 | 2020-12-22 | Kodiak Sciences Inc. | Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| IL293131A (en) | 2019-11-25 | 2022-07-01 | Univ California | Long-acting vegf inhibitors for intraocular neovascularization |
| AU2020396699B2 (en) * | 2019-12-04 | 2024-07-18 | Cdmogen Co., Ltd | Composition for treating diabetic retinopathy, comprising rAAV containing soluble VEGFR-1 variant cDNA |
| CN111826400A (zh) * | 2020-07-21 | 2020-10-27 | 中科宝承生物医学科技有限公司 | 一种双特异性抗体nk细胞制备方法及其细胞和应用 |
| CN112961250B (zh) * | 2021-03-01 | 2023-06-06 | 长春金赛药业有限责任公司 | 抗体融合蛋白及其应用 |
| CN113105558A (zh) * | 2021-04-01 | 2021-07-13 | 芜湖英特菲尔生物制品产业研究院有限公司 | 一种酿酒酵母表达人rPDGF-HSA融合蛋白及其标准品的制备方法 |
| JP2024525186A (ja) * | 2021-06-18 | 2024-07-10 | イカロベック リミテッド | 網膜障害 |
| WO2023199951A1 (ja) * | 2022-04-13 | 2023-10-19 | 株式会社セルージョン | 抗ｖｅｇｆ機能を有する多能性幹細胞及びその分化細胞 |
| US11723955B1 (en) | 2022-05-13 | 2023-08-15 | Allgenesis Biotherapeutics Inc. | VEGFR fusion protein pharmaceutical composition |
| KR102764987B1 (ko) * | 2022-08-02 | 2025-02-12 | 주식회사 파노로스바이오사이언스 | 변형된 융합 단백질 및 이의 용도 |
| WO2025033876A1 (ko) * | 2023-08-04 | 2025-02-13 | 주식회사 파노로스바이오사이언스 | 변형된 융합 단백질과 scFv의 결합체 및 이의 용도 |
| WO2025042305A1 (ru) * | 2023-08-18 | 2025-02-27 | Общество с ограниченной ответственностью "Пальмира Биофарма" | Нуклеотидная последовательность, кодирующпя слитый белок pdgfra-hfc |
Family Cites Families (37)
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|---|---|---|---|---|
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4454151A (en) | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| US4952515A (en) | 1987-05-22 | 1990-08-28 | Polymer Technology International Corp. | Method of detection using a test strip having a non particulate dialyzed polymer layer |
| EP0435911B1 (en) | 1988-09-23 | 1996-03-13 | Cetus Oncology Corporation | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| US5328470A (en) | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| KR0185215B1 (ko) | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
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| US5178635A (en) | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
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| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
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| HUE060464T2 (hu) | 2013-03-13 | 2023-03-28 | Genzyme Corp | PDGF- és VEGF-kötõrészeket tartalmazó fúziós fehérjék és eljárások azok alkalmazására |
-
2014
- 2014-03-13 HU HUE14722439A patent/HUE060464T2/hu unknown
- 2014-03-13 SG SG11201506802SA patent/SG11201506802SA/en unknown
- 2014-03-13 PL PL14722439.8T patent/PL2968461T3/pl unknown
- 2014-03-13 MX MX2015011951A patent/MX363533B/es unknown
- 2014-03-13 EP EP14722439.8A patent/EP2968461B1/en active Active
- 2014-03-13 TW TW103109211A patent/TWI631133B/zh not_active IP Right Cessation
- 2014-03-13 CN CN201480026585.2A patent/CN105188733B/zh active Active
- 2014-03-13 US US14/210,354 patent/US9637534B2/en active Active
- 2014-03-13 SG SG10201707501TA patent/SG10201707501TA/en unknown
- 2014-03-13 AR ARP140100983A patent/AR095437A1/es unknown
- 2014-03-13 RS RS20221155A patent/RS63820B1/sr unknown
- 2014-03-13 DK DK14722439.8T patent/DK2968461T3/da active
- 2014-03-13 UY UY0001035407A patent/UY35407A/es not_active Application Discontinuation
- 2014-03-13 SG SG10201912956YA patent/SG10201912956YA/en unknown
- 2014-03-13 FI FIEP14722439.8T patent/FI2968461T3/fi active
- 2014-03-13 LT LTEPPCT/US2014/026872T patent/LT2968461T/lt unknown
- 2014-03-13 HR HRP20221447TT patent/HRP20221447T1/hr unknown
- 2014-03-13 SI SI201432005T patent/SI2968461T1/sl unknown
- 2014-03-13 BR BR112015022208A patent/BR112015022208A8/pt not_active IP Right Cessation
- 2014-03-13 ES ES14722439T patent/ES2933558T3/es active Active
- 2014-03-13 RU RU2015142999A patent/RU2692652C2/ru active
- 2014-03-13 CA CA2904623A patent/CA2904623A1/en not_active Abandoned
- 2014-03-13 KR KR1020157027849A patent/KR102228921B1/ko not_active Expired - Fee Related
- 2014-03-13 PT PT147224398T patent/PT2968461T/pt unknown
- 2014-03-13 JP JP2016502268A patent/JP6561042B2/ja active Active
- 2014-03-13 WO PCT/US2014/026872 patent/WO2014160507A1/en not_active Ceased
- 2014-03-13 AU AU2014243712A patent/AU2014243712B2/en active Active
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2015
- 2015-08-31 IL IL240950A patent/IL240950B/en active IP Right Grant
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2017
- 2017-03-28 US US15/471,725 patent/US10183983B2/en active Active
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2018
- 2018-11-20 US US16/197,194 patent/US11084864B2/en active Active
- 2018-12-12 AU AU2018278902A patent/AU2018278902A1/en not_active Abandoned
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2019
- 2019-02-04 JP JP2019017599A patent/JP2019123711A/ja active Pending
- 2019-05-19 IL IL266715A patent/IL266715A/en unknown
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2021
- 2021-07-02 US US17/367,027 patent/US20220064262A1/en not_active Abandoned