JP2016512194A5 - - Google Patents

Download PDF

Info

Publication number
JP2016512194A5
JP2016512194A5 JP2015561540A JP2015561540A JP2016512194A5 JP 2016512194 A5 JP2016512194 A5 JP 2016512194A5 JP 2015561540 A JP2015561540 A JP 2015561540A JP 2015561540 A JP2015561540 A JP 2015561540A JP 2016512194 A5 JP2016512194 A5 JP 2016512194A5
Authority
JP
Japan
Prior art keywords
amino
bromophenyl
optionally substituted
carbamoyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015561540A
Other languages
English (en)
Japanese (ja)
Other versions
JP6196328B2 (ja
JP2016512194A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/020273 external-priority patent/WO2014138046A1/en
Publication of JP2016512194A publication Critical patent/JP2016512194A/ja
Publication of JP2016512194A5 publication Critical patent/JP2016512194A5/ja
Application granted granted Critical
Publication of JP6196328B2 publication Critical patent/JP6196328B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015561540A 2013-03-06 2014-03-04 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用 Expired - Fee Related JP6196328B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773778P 2013-03-06 2013-03-06
US61/773,778 2013-03-06
PCT/US2014/020273 WO2014138046A1 (en) 2013-03-06 2014-03-04 Use of agonists of formyl peptide receptor 2 for treating dermatological diseases

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2017157336A Division JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157337A Division JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Publications (3)

Publication Number Publication Date
JP2016512194A JP2016512194A (ja) 2016-04-25
JP2016512194A5 true JP2016512194A5 (enExample) 2017-04-13
JP6196328B2 JP6196328B2 (ja) 2017-09-13

Family

ID=50389505

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015561540A Expired - Fee Related JP6196328B2 (ja) 2013-03-06 2014-03-04 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157337A Expired - Fee Related JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157336A Expired - Fee Related JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2019043933A Expired - Fee Related JP6672499B2 (ja) 2013-03-06 2019-03-11 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2017157337A Expired - Fee Related JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157336A Expired - Fee Related JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2019043933A Expired - Fee Related JP6672499B2 (ja) 2013-03-06 2019-03-11 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Country Status (13)

Country Link
US (5) US20140256685A1 (enExample)
EP (1) EP2964214A1 (enExample)
JP (4) JP6196328B2 (enExample)
KR (2) KR102223384B1 (enExample)
CN (2) CN107714683A (enExample)
AR (1) AR095035A1 (enExample)
AU (3) AU2014226001B2 (enExample)
BR (2) BR112015021392B1 (enExample)
CA (3) CA2899804A1 (enExample)
HK (2) HK1219661A1 (enExample)
RU (1) RU2696487C2 (enExample)
TW (1) TW201446241A (enExample)
WO (1) WO2014138046A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE040145T2 (hu) * 2011-10-26 2019-02-28 Allergan Inc N-karbamid szubsztituált aminosavak amid származékai mint formilpeptidszerû receptor 1 (FPRL1) receptormodulátorok
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
EP2850058B1 (en) 2012-05-16 2016-07-13 Actelion Pharmaceuticals Ltd. 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists
MA37618B1 (fr) 2012-05-16 2017-08-31 Actelion Pharmaceuticals Ltd Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
AU2014226001B2 (en) * 2013-03-06 2018-12-06 Allergan, Inc. Use of agonists of Formyl peptide receptor 2 for treating dermatological diseases
AR096686A1 (es) 2013-06-25 2016-01-27 Actelion Pharmaceuticals Ltd Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx
KR102313757B1 (ko) * 2013-07-16 2021-10-18 알러간, 인코포레이티드 펩타이드 수용체 조절제로서의 n-우레아 치환된 아미노산의 유도체
BR112016001106A8 (pt) 2013-07-18 2017-12-26 Actelion Pharmaceuticals Ltd Derivados de espiro [2,4] heptano interligados piperazina substituídos como agonistas do receptor de alx
AR097279A1 (es) 2013-08-09 2016-03-02 Actelion Pharmaceuticals Ltd Derivados de benzimidazolil-metil urea como agonistas del receptor de alx
US9920013B2 (en) 2014-01-29 2018-03-20 Allergan, Inc. 2,5-dioxoimidazolidin-1-yl-3-urea derivatives as formyl peptide modulators
US9663457B2 (en) 2014-04-09 2017-05-30 Allergan, Inc. Carbamoyl hydrazine derivatives as formyl peptide modulators
KR20170005121A (ko) 2014-05-21 2017-01-11 알러간, 인코포레이티드 폼일 펩타이드 수용체 조절제로서의 이미다졸 유도체
US10717708B2 (en) * 2015-12-10 2020-07-21 Bristol-Myers Squibb Company Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists
AU2017241767B2 (en) * 2016-03-28 2021-07-22 Allergan, Inc. Phenyl urea derivatives as N-formyl peptide receptor modulators
WO2017180323A1 (en) * 2016-04-12 2017-10-19 Allergan, Inc. Phenyl urea derivatives as n-formyl peptide receptor modulators
TWI746660B (zh) * 2016-10-06 2021-11-21 日商第一三共股份有限公司 尿素衍生物及其用途
GB2561540A (en) * 2017-03-13 2018-10-24 Nodthera Ltd Chemical compounds
ES2799098B2 (es) * 2019-06-10 2021-12-10 Univ Madrid Carlos Iii Aptameros agonistas del receptor fpr2 y usos de los mismos

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521210A (en) 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
JPS63232846A (ja) 1987-03-20 1988-09-28 Haruo Ogura 新規な固定相担体
AU6909300A (en) * 1999-08-20 2001-03-19 Merck & Co., Inc. Substituted ureas as cell adhesion inhibitors
DE10005275A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Neuartige Glycokonjugate
EP1162194A1 (en) 2000-06-06 2001-12-12 Aventis Pharma Deutschland GmbH Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
DE10063008A1 (de) 2000-12-16 2002-06-20 Merck Patent Gmbh Carbonsäureamidderivate
CA2495284A1 (en) * 2002-09-05 2004-03-18 Neurosearch A/S Diarylurea derivatives and their use as chloride channel blockers
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
WO2005058823A1 (ja) 2003-12-17 2005-06-30 Takeda Pharmaceutical Company Limited ウレア誘導体、その製造法及び用途
WO2006065755A2 (en) 2004-12-13 2006-06-22 Glaxo Group Limited Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
WO2007076055A2 (en) * 2005-12-22 2007-07-05 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
KR20090121832A (ko) * 2008-05-23 2009-11-26 인제대학교 산학협력단 2-(2-히드록시벤조일)히드라진카르복시아미드 유도체 또는이의 약학적으로 허용가능한 염, 이의 제조방법, 및 이를유효 성분으로 함유하는 선택적 면역 억제용 약학적 조성물
WO2010056778A1 (en) * 2008-11-11 2010-05-20 Signum Biosciences, Inc. Isoprenyl compounds and methods thereof
WO2010104306A2 (ko) * 2009-03-07 2010-09-16 주식회사 메디젠텍 세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
WO2011073918A2 (en) * 2009-12-16 2011-06-23 Actelion Pharmaceuticals Ltd Peptides as modulators of fprl1 and/or fprl2
EP2585054A1 (en) * 2010-06-24 2013-05-01 Allergan, Inc. Derivatives of cycloalkyl- and cycloalkenyl-1,2-dicarboxylic acid compounds having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity
AU2011336973A1 (en) * 2010-12-03 2013-07-11 Allergan, Inc. Pharmaceutical compositions comprising 3,4- dihydroisoquinolin-2(1 H)-yl-3-phenylurea derivatives having formyl peptide receptor like-1 (FPRL-1) agonist or antagonist activity
WO2012109544A1 (en) 2011-02-11 2012-08-16 Allergan, Inc. Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators
US8653299B2 (en) 2011-03-17 2014-02-18 Allergan, Inc. Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
US20120329873A1 (en) 2011-06-17 2012-12-27 Li yong-xin D-serine for the treatment of visual system disorders
EP2731931A1 (en) 2011-07-11 2014-05-21 Allergan, Inc. Polycyclic pyrrolidine-2,5-dione derivatives as -formyl peptide receptor like-1 (fprl-1) receptor modulators
HUE040145T2 (hu) * 2011-10-26 2019-02-28 Allergan Inc N-karbamid szubsztituált aminosavak amid származékai mint formilpeptidszerû receptor 1 (FPRL1) receptormodulátorok
US8492556B2 (en) * 2011-11-10 2013-07-23 Allergan, Inc. 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators
US8541577B2 (en) * 2011-11-10 2013-09-24 Allergan, Inc. Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators
EP2814815A1 (en) 2012-02-16 2014-12-24 Allergan, Inc. Imidazolidine-2,4-dione derivatives as n-formyl peptide receptor 2 modulators
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
AU2014226001B2 (en) * 2013-03-06 2018-12-06 Allergan, Inc. Use of agonists of Formyl peptide receptor 2 for treating dermatological diseases
EP2964213B1 (en) * 2013-03-06 2020-11-04 Allergan, Inc. Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
KR102313757B1 (ko) * 2013-07-16 2021-10-18 알러간, 인코포레이티드 펩타이드 수용체 조절제로서의 n-우레아 치환된 아미노산의 유도체
US20150080466A1 (en) 2013-09-19 2015-03-19 Allergan, Inc. Diphenyl urea derivatives as formyl peptide receptor modulators
BR112016011417A8 (pt) 2013-11-21 2020-05-05 Allergan Inc derivados de fenilcarbamatos como moduladores do receptor de formil peptídeo, composição farmacêutica, e seus usos
KR20170005121A (ko) * 2014-05-21 2017-01-11 알러간, 인코포레이티드 폼일 펩타이드 수용체 조절제로서의 이미다졸 유도체

Similar Documents

Publication Publication Date Title
RU2015134778A (ru) Применение агонистов формилпептидного рецептора 2 для лечения дерматологических заболеваний
RU2015136774A (ru) Применение агонистов формилпептидного рецептора 2 для лечения воспалительных заболеваний глаз
JP2016512193A5 (enExample)
RU2424233C2 (ru) Производные бензимидазола, методы их получения, применение их в качестве агонистов фарнезоид-х-рецептора (fxr) и содержащие их фармацевтические препараты
KR101363278B1 (ko) 이미다졸계 lxr 변조제
RU2014120013A (ru) Амидные производные n-карбамид-замещенных аминокислот как модуляторы формилпептидного рецептора-1 (fprl-1)
RU2014122753A (ru) Производные 2,5-диоксоимидазолидин-1-ил-3-фенилмочевины в качестве модуляторов формилпептидного рецептора 1 (fprl-1)
RU2012117885A (ru) 2,3,5-тризамещенные пирролы, фармацевтическая композиция и лекарственное средство (варианты) на их основе, способ получения соединений (варианты)
JP2013506637A5 (enExample)
KR20050025189A (ko) 화학 화합물
AU2009217518A1 (en) 2-aminoimidazole beta-secretase inhibitors for the treatment of Alzheimer's disease
RU2011107227A (ru) Бензоимидазольные производные и ингибиторы гликоген-синтаза-киназы-3 бета, содержащие такие производные
EA200970604A1 (ru) Новое промежуточное соединение и способ, используемый для получения {2-[1-(3,5-бис-трифторметилбензил)-5-пиридин-4-ил-1н-[1,2,3]триазол-4-ил]пиридин-3-ил}-(2-хлорфенил)метанона
BG65858B1 (bg) 1,2-диарилбензимидазоли и фармацевтичното им използване
JP2006522820A5 (enExample)
HRP20170338T1 (hr) Fluorometil-supstituirani pirolkarboksamidi
AR068065A1 (es) Derivados de tetrahidroquinolinas, antagonistas de receptores de tsh, composiciones farmaceuticas que los contienen y usos de los mismos en enfermedades asociadas a desordenes tiroideos.
JP2001039870A (ja) 片頭痛治療のための組み合わせ療法
JP2010533185A5 (enExample)
JP2012528843A5 (enExample)
TH93934B (th) เกลือมาเอลเอต, ทอสิเลต, ฟิวมาเรต, และออกซาเลตของ5-(1(s)-อะมิโน-2-ไฮดรอกซีเอธิล)- -n-[(2,4-ไดฟลูออโร-เฟนิล)-เมธิล]-2-[8-เมธอกซี-2-(ไตรฟลูออโรเมธิล)-5-ควิโนลีน]-4-ออกซาโซลคาร์บอกซามีด และกระบวนการของการเตรียมเพื่อประสงค์อย่างนั้น