|
US3472859A
(en)
|
1966-11-01 |
1969-10-14 |
Sterling Drug Inc |
1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
|
|
JPS4826772Y1
(enExample)
|
1969-04-04 |
1973-08-06 |
|
|
|
ATE27451T1
(de)
|
1981-03-24 |
1987-06-15 |
Ciba Geigy Ag |
Acyl-chinolinonderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische praeparate und ihre verwendung.
|
|
US4910327A
(en)
|
1982-05-25 |
1990-03-20 |
American Cyanamid Company |
Alkyl esters of substituted 2-methyl-3-quinolinecarboxylic acid and quinoline-2,3-dicarboxylic acid: dialkyl 3-(substituted)phenylaminobut-2-ene-dioates and methods for the preparation thereof
|
|
US4656283A
(en)
|
1982-05-25 |
1987-04-07 |
American Cyanamid Company |
Alkyl esters of substituted 2-methyl-3-quinolinecarboxylic acid and quinoline-2,3-dicarboxylic acid
|
|
PT79699B
(en)
|
1983-12-22 |
1986-12-10 |
Pfizer |
Process for preparing quinolone inotropic agents
|
|
FR2634483B2
(fr)
|
1987-12-29 |
1994-03-04 |
Esteve Labor Dr |
Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
|
|
CA2002864C
(en)
|
1988-11-29 |
1999-11-16 |
Eddy J. E. Freyne |
(1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
|
|
CA2102780C
(en)
|
1991-05-10 |
2007-01-09 |
Alfred P. Spada |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase
|
|
US5478832A
(en)
|
1992-05-08 |
1995-12-26 |
The Green Cross Corporation |
Quinoline compounds
|
|
JPH0826772A
(ja)
|
1994-07-22 |
1996-01-30 |
Sony Corp |
融着用ガラス、その製造方法及び製造装置、並びに磁気ヘッドの製造方法
|
|
DE69512495T2
(de)
|
1994-10-27 |
2000-02-03 |
Asahi Glass Co. Ltd., Tokio/Tokyo |
Verfahren zur Herstellung von Chinolin-2-yl-benzoesäure
|
|
GB9523267D0
(en)
|
1995-11-14 |
1996-01-17 |
Sandoz Ltd |
Organic compounds
|
|
EE03484B1
(et)
|
1995-12-08 |
2001-08-15 |
Janssen Pharmaceutica N.V. |
Farnesüülproteiintransferaasi inhibeerivad (5-imidasolüül)metüül-2-kinolinooni derivaadid ja nende kasutamine
|
|
JP2000511532A
(ja)
|
1996-05-20 |
2000-09-05 |
メルク エンド カンパニー インコーポレーテッド |
性腺刺激ホルモン放出ホルモンのアンタゴニスト
|
|
ATE222104T1
(de)
|
1997-06-02 |
2002-08-15 |
Janssen Pharmaceutica Nv |
(imidazol-5-yl)methyl-2-quinolinone derivativen als inhibitoren von proliferation der glatten muskelzellen
|
|
RU2220960C2
(ru)
|
1997-12-22 |
2004-01-10 |
Фармация Энд Апджон Компани |
4-гидрокси-3-хинолинкарбоксамиды и гидразиды, фармацевтическая композиция и способ лечения на их основе
|
|
FR2776388B1
(fr)
|
1998-03-20 |
2006-04-28 |
Lipha |
Utilisation de recepteurs de la famille ror pour le criblage de substances utiles pour le traitement de l'atherosclerose
|
|
US6399629B1
(en)
|
1998-06-01 |
2002-06-04 |
Microcide Pharmaceuticals, Inc. |
Efflux pump inhibitors
|
|
US6545020B1
(en)
|
1998-07-06 |
2003-04-08 |
Janssen Pharmaceutica, N.V. |
Farnesyl Protein transferase inhibitors with in vivo radiosensitizing properties
|
|
HRP20000904A2
(en)
*
|
1998-07-06 |
2001-12-31 |
Janssen Pharmaceutica Nv |
Farnesyl protein transferase inhibitors for treating arthropathies
|
|
JP2000169451A
(ja)
|
1998-09-30 |
2000-06-20 |
Kyorin Pharmaceut Co Ltd |
６，７―ジ置換キノリンカルボン酸誘導体とその付加塩及びそれらの製造方法
|
|
BR9916827A
(pt)
|
1998-12-23 |
2001-10-16 |
Janssen Pharmaceutica Nv |
Derivados de quinolina 1,2-anelados
|
|
US6248739B1
(en)
|
1999-01-08 |
2001-06-19 |
Pharmacia & Upjohn Company |
Quinolinecarboxamides as antiviral agents
|
|
US6248736B1
(en)
|
1999-01-08 |
2001-06-19 |
Pharmacia & Upjohn Company |
4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
|
|
KR20010102073A
(ko)
|
1999-02-11 |
2001-11-15 |
실버스타인 아써 에이. |
항암제로 유용한 헤테로아릴-치환된 퀴놀린-2-온 유도체
|
|
DE60008206T2
(de)
|
1999-11-30 |
2004-12-02 |
Pfizer Products Inc., Groton |
Chinolinderivate verwendbar zur Hemmung der Farnesyl-Protein Transferase
|
|
SI1255537T1
(sl)
|
2000-02-04 |
2006-10-31 |
Janssen Pharmaceutica Nv |
Inhibitorji farnezil protein transferaze za zdravljenje raka dojk
|
|
US6838467B2
(en)
|
2000-02-24 |
2005-01-04 |
Janssen Pharmaceutica N. V. |
Dosing regimen
|
|
US20030212008A1
(en)
|
2000-02-29 |
2003-11-13 |
Palmer Peter Albert |
Farnesyl protein transferase inhibitor combinations with further anti-cancer agents
|
|
EP1261348A2
(en)
|
2000-02-29 |
2002-12-04 |
Janssen Pharmaceutica N.V. |
Combinations of a farnesyl protein transferase inhibitor with nitrogen mustard or nitrosourea alkylating agents
|
|
WO2001064195A2
(en)
|
2000-02-29 |
2001-09-07 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
|
|
CA2397657A1
(en)
|
2000-02-29 |
2001-09-07 |
Janssen Pharmaceutica Inc. |
Farnesyl protein transferase inhibitor combinations with platinum compounds
|
|
JP2003525234A
(ja)
|
2000-02-29 |
2003-08-26 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
カンプトテシン化合物とのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
|
|
CA2397475A1
(en)
|
2000-02-29 |
2001-09-07 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations with vinca alkaloids
|
|
US20030181473A1
(en)
|
2000-02-29 |
2003-09-25 |
Palmer Peter Albert |
Farnesyl protein transferase inhibitor combinations with taxane compounds
|
|
AU2001239275A1
(en)
|
2000-02-29 |
2001-09-12 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives
|
|
CA2397253A1
(en)
|
2000-02-29 |
2001-09-07 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
|
|
US20030022918A1
(en)
|
2000-02-29 |
2003-01-30 |
Horak Ivan David |
Farnesyl protein transferase inhibitor combinations with an her2 antibody
|
|
EP1261342A2
(en)
|
2000-02-29 |
2002-12-04 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitor combinations
|
|
US6844357B2
(en)
|
2000-05-01 |
2005-01-18 |
Pfizer Inc. |
Substituted quinolin-2-one derivatives useful as antiproliferative agents
|
|
US6525049B2
(en)
|
2000-07-05 |
2003-02-25 |
Pharmacia & Upjohn Company |
Pyrroloquinolones as antiviral agents
|
|
PT1299395E
(pt)
|
2000-07-12 |
2005-01-31 |
Upjohn Co |
Oxazinoquinolonas uteis para o tratamento de infeccoes provocadas por virus
|
|
US6624159B2
(en)
|
2000-07-12 |
2003-09-23 |
Pharmacia & Upjohn Company |
Heterocycle carboxamides as antiviral agents
|
|
WO2002024686A2
(en)
|
2000-09-25 |
2002-03-28 |
Janssen Pharmaceutica N.V. |
Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives
|
|
JP4974439B2
(ja)
|
2000-09-25 |
2012-07-11 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
ファルネシルトランスフェラーゼを阻害する６−ヘテロシクリルメチルキノリノン誘導体
|
|
ATE321038T1
(de)
|
2000-09-25 |
2006-04-15 |
Janssen Pharmaceutica Nv |
Chinolin- und chinazolinderivate und deren verwendung als farnesyl transferase inhibitoren
|
|
IL155163A0
(en)
|
2000-10-02 |
2003-10-31 |
Janssen Pharmaceutica Nv |
Metabotropic glutamate receptor antagonists
|
|
WO2002043733A1
(en)
|
2000-11-28 |
2002-06-06 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitors for the treatment of inflammatory bowel disease
|
|
WO2002051835A1
(en)
|
2000-12-27 |
2002-07-04 |
Janssen Pharmaceutica N.V. |
Farnesyl transferase inhibiting 4-substituted quinoline and quinazoline derivatives
|
|
ES2318000T3
(es)
|
2001-02-15 |
2009-05-01 |
Janssen Pharmaceutica Nv |
Combinaciones de inhibidores de la farnesil-protein-transferasa con agentes antiestrogenos.
|
|
CA2433467A1
(en)
|
2001-03-01 |
2002-09-12 |
Joseph W. Strohbach |
Substituted quinolinecarboxamides as antiviral agents
|
|
EP1390033A1
(en)
|
2001-04-25 |
2004-02-25 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibitors for treating cachexia
|
|
EP1412367A4
(en)
|
2001-06-21 |
2006-05-03 |
Ariad Pharma Inc |
NEW CHINOLINE AND ITS USE
|
|
AR037940A1
(es)
|
2001-12-20 |
2004-12-22 |
Upjohn Co |
Compuestos antivirales de piridoquinoxalina
|
|
AU2002352882A1
(en)
|
2001-12-20 |
2003-07-09 |
Pharmacia And Upjohn Company |
Pyridoquinoxaline antivirals
|
|
UA78548C2
(en)
|
2002-03-29 |
2007-04-10 |
Janssen Pharmaceutica Nv |
Radiolabelled quinoline and quinolinone derivatives and use thereof as metabotropic ligands of glutamate receptor
|
|
DE60322920D1
(de)
|
2002-08-13 |
2008-09-25 |
Shionogi & Co |
Heterocyclische verbindungen mit hiv-integrase-hemmender wirkung
|
|
US20040186131A1
(en)
|
2002-08-30 |
2004-09-23 |
Wathen Michael W |
Method of preventing or treating atherosclerosis or restenosis
|
|
GB0222516D0
(en)
|
2002-09-27 |
2002-11-06 |
Karobio Ab |
Novel compounds
|
|
TWI335328B
(en)
|
2003-07-14 |
2011-01-01 |
Arena Pharm Inc |
Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related hereto
|
|
AU2004295058B9
(en)
|
2003-11-20 |
2011-06-30 |
Janssen Pharmaceutica N.V. |
6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors
|
|
EP1709012B1
(en)
|
2003-12-05 |
2015-07-29 |
Janssen Pharmaceutica NV |
6-substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose)polymerase inhibitors
|
|
WO2005058843A1
(en)
|
2003-12-10 |
2005-06-30 |
Janssen Pharmaceutica N.V. |
Substituted 6-cyclohexylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors
|
|
PE20050676A1
(es)
|
2003-12-12 |
2005-11-02 |
Wyeth Corp |
Quinolinas referidas a enfermedades cardiovasculares
|
|
ATE444068T1
(de)
|
2004-01-23 |
2009-10-15 |
Janssen Pharmaceutica Nv |
Chinolinderivate und ihre verwendung als mycobakterielle inhibitoren
|
|
MXPA06008596A
(es)
|
2004-01-29 |
2006-08-28 |
Janssen Pharmaceutica Nv |
Derivados de quinolina para uso como inhibidores micobacterianos.
|
|
JP2005225250A
(ja)
|
2004-02-10 |
2005-08-25 |
Murakami Corp |
車載用監視装置
|
|
WO2006003150A1
(en)
|
2004-06-30 |
2006-01-12 |
Janssen Pharmaceutica N.V. |
Substituted 2-alkyl quinazolinone derivatives as parp inhibitors
|
|
AU2005268166B2
(en)
|
2004-08-04 |
2011-10-20 |
Meiji Seika Pharma Co., Ltd. |
Quinoline derivative and insecticide containing same as active constituent
|
|
KR100686531B1
(ko)
|
2004-08-31 |
2007-02-23 |
한국화학연구원 |
히스톤 디아세틸라제 저해활성을 갖는 아릴아미노메틸프로페닐 벤즈하이드록시아마이드 유도체 및 그의 제조방법
|
|
EP1815247B1
(en)
|
2004-11-05 |
2013-02-20 |
Janssen Pharmaceutica NV |
Therapeutic use of farnesyltransferase inhibitors and methods of monitoring the efficacy thereof
|
|
JO2855B1
(en)
|
2005-08-03 |
2015-03-15 |
شركة جانسين فارماسوتيكا ان. في |
Quinoline derivatives acting as antibacterial agents
|
|
JO2952B1
(en)
|
2005-08-03 |
2016-03-15 |
جانسين فارماسوتيكا ان. في |
Quinoline derivatives acting as antibacterial agents
|
|
WO2007088978A1
(ja)
|
2006-02-03 |
2007-08-09 |
Meiji Seika Kaisha, Ltd. |
新規キノリン誘導体およびこれを有効成分として含有する農園芸用殺菌剤
|
|
US8389739B1
(en)
|
2006-10-05 |
2013-03-05 |
Orphagen Pharmaceuticals |
Modulators of retinoid-related orphan receptor gamma
|
|
KR101083177B1
(ko)
|
2006-10-23 |
2011-11-11 |
에스지엑스 파마슈티컬스, 인코포레이티드 |
트리아졸로-피리다진 단백질 키나제 조정제
|
|
JO3271B1
(ar)
|
2006-12-06 |
2018-09-16 |
Janssen Pharmaceutica Nv |
مشتقات الكوينولين المضادة للجراثيم
|
|
AR065093A1
(es)
|
2007-02-05 |
2009-05-13 |
Merck Frosst Canada Ltd |
Compuestos farmacéuticos inhibidores de la biosintesis de leucotrienos
|
|
UY30892A1
(es)
|
2007-02-07 |
2008-09-02 |
Smithkline Beckman Corp |
Inhibidores de la actividad akt
|
|
EP2155197A4
(en)
|
2007-03-09 |
2011-10-12 |
Link Medicine Corp |
TREATMENT OF LYSOSOMAL STORAGE DISEASES
|
|
KR101156845B1
(ko)
|
2007-05-21 |
2012-06-18 |
에스지엑스 파마슈티컬스, 인코포레이티드 |
헤테로시클릭 키나제 조절제
|
|
CN101143845B
(zh)
|
2007-10-15 |
2010-08-25 |
中国药科大学 |
取代喹啉甲酰胍衍生物、其制备方法及其医药用途
|
|
WO2009091735A1
(en)
|
2008-01-18 |
2009-07-23 |
Allergan.Inc |
Substitued-aryl-(imidazole)-methyl)-phenyl compounds as subtype selective modulators of alpha 2b and/or alpha 2c adrenergic receptors
|
|
CA2714232A1
(en)
|
2008-02-05 |
2009-08-13 |
Pfizer Inc. |
Pyridinyl amides for the treatment of cns and metabolic disorders
|
|
WO2009140138A1
(en)
|
2008-05-13 |
2009-11-19 |
Allergan, Inc. |
Quinolynylmethylimidizoles as therapeutic agents
|
|
WO2010068296A1
(en)
|
2008-12-11 |
2010-06-17 |
Stiefel Laboratories, Inc. |
Piperazine carboxamidines as antimicrobial agents
|
|
WO2010127208A1
(en)
|
2009-04-30 |
2010-11-04 |
Forest Laboratories Holdings Limited |
Inhibitors of acetyl-coa carboxylase
|
|
CN101899011B
(zh)
|
2009-05-26 |
2013-01-16 |
北京大学 |
氨基二硫代甲酸酯类化合物、其制备方法和应用
|
|
TWI428332B
(zh)
|
2009-06-09 |
2014-03-01 |
Hoffmann La Roche |
雜環抗病毒化合物
|
|
EA201270013A1
(ru)
|
2009-06-25 |
2012-06-29 |
Амген Инк. |
Гетероциклические соединения и их применение
|
|
MX2012002179A
(es)
|
2009-08-20 |
2012-03-16 |
Novartis Ag |
Compuestos heterociclicos de oxima.
|
|
EP2368886A1
(en)
|
2010-03-01 |
2011-09-28 |
Phenex Pharmaceuticals AG |
Novel compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (ROR gamma, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune desease
|
|
US9101600B2
(en)
|
2010-03-11 |
2015-08-11 |
New York University |
Compounds as RORγt modulators and uses thereof
|
|
WO2011130707A2
(en)
|
2010-04-15 |
2011-10-20 |
Chromocell Corporation |
Compounds, compositions, and methods for reducing or eliminating bitter taste
|
|
JP6063870B2
(ja)
*
|
2010-11-08 |
2017-01-18 |
ライセラ・コーポレイション |
ＲＯＲγ活性の阻害用のＮ−スルホニル化テトラヒドロキノリンおよび関連二環化合物および病気の治療
|
|
CA2826773C
(en)
|
2011-02-24 |
2019-07-16 |
Emory University |
Jab1 blocking compositions for ossification and methods related thereto
|
|
EP2927217B1
(en)
|
2011-04-28 |
2018-01-17 |
Japan Tobacco Inc. |
Amide compound and pharmaceutical application therefor
|
|
WO2012158784A2
(en)
|
2011-05-16 |
2012-11-22 |
Theodore Mark Kamenecka |
Modulators of the nuclear hormone receptor ror
|
|
GB201118652D0
(en)
|
2011-10-28 |
2011-12-07 |
Astex Therapeutics Ltd |
New compounds
|
|
WO2013064231A1
(en)
|
2011-10-31 |
2013-05-10 |
Phenex Pharmaceuticals Ag |
SEVEN-MEMBERED SULFONAMIDES AS MODULATORS OF RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORγ, NR1F3)
|
|
US9815851B2
(en)
|
2011-12-02 |
2017-11-14 |
Phenex Pharmaceuticals Ag |
Pyrrolo carboxamides as modulators of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases
|