JP2015533176A5 - - Google Patents
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- JP2015533176A5 JP2015533176A5 JP2015537018A JP2015537018A JP2015533176A5 JP 2015533176 A5 JP2015533176 A5 JP 2015533176A5 JP 2015537018 A JP2015537018 A JP 2015537018A JP 2015537018 A JP2015537018 A JP 2015537018A JP 2015533176 A5 JP2015533176 A5 JP 2015533176A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- ezh2
- pharmaceutically acceptable
- compound according
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261714145P | 2012-10-15 | 2012-10-15 | |
| US201261714140P | 2012-10-15 | 2012-10-15 | |
| US61/714,145 | 2012-10-15 | ||
| US61/714,140 | 2012-10-15 | ||
| US201361780703P | 2013-03-13 | 2013-03-13 | |
| US61/780,703 | 2013-03-13 | ||
| US201361786277P | 2013-03-14 | 2013-03-14 | |
| US61/786,277 | 2013-03-14 | ||
| PCT/US2013/065126 WO2014062732A1 (en) | 2012-10-15 | 2013-10-15 | Substituted benzene compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028891A Division JP2018087238A (ja) | 2012-10-15 | 2018-02-21 | 置換ベンゼン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015533176A JP2015533176A (ja) | 2015-11-19 |
| JP2015533176A5 true JP2015533176A5 (enExample) | 2016-12-01 |
| JP6461802B2 JP6461802B2 (ja) | 2019-01-30 |
Family
ID=50475881
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015537018A Expired - Fee Related JP6461802B2 (ja) | 2012-10-15 | 2013-10-15 | 置換ベンゼン化合物 |
| JP2015537019A Expired - Fee Related JP6461803B2 (ja) | 2012-10-15 | 2013-10-15 | 置換ベンゼン化合物 |
| JP2018028907A Active JP6559275B2 (ja) | 2012-10-15 | 2018-02-21 | 置換ベンゼン化合物 |
| JP2018028891A Withdrawn JP2018087238A (ja) | 2012-10-15 | 2018-02-21 | 置換ベンゼン化合物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015537019A Expired - Fee Related JP6461803B2 (ja) | 2012-10-15 | 2013-10-15 | 置換ベンゼン化合物 |
| JP2018028907A Active JP6559275B2 (ja) | 2012-10-15 | 2018-02-21 | 置換ベンゼン化合物 |
| JP2018028891A Withdrawn JP2018087238A (ja) | 2012-10-15 | 2018-02-21 | 置換ベンゼン化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (8) | US9006242B2 (enExample) |
| EP (4) | EP3628662A1 (enExample) |
| JP (4) | JP6461802B2 (enExample) |
| KR (2) | KR102057365B1 (enExample) |
| CN (3) | CN105102431B (enExample) |
| AR (1) | AR093244A1 (enExample) |
| AU (2) | AU2013331380B2 (enExample) |
| BR (2) | BR112015008480A2 (enExample) |
| CA (2) | CA2887562C (enExample) |
| CL (2) | CL2015000942A1 (enExample) |
| HK (2) | HK1213264A1 (enExample) |
| IL (4) | IL238135B (enExample) |
| MX (2) | MX353929B (enExample) |
| MY (1) | MY180311A (enExample) |
| NZ (2) | NZ706738A (enExample) |
| PE (2) | PE20150887A1 (enExample) |
| PH (2) | PH12015500800B1 (enExample) |
| RU (2) | RU2662436C2 (enExample) |
| SG (3) | SG11201502803VA (enExample) |
| TW (2) | TWI588131B (enExample) |
| UA (2) | UA119136C2 (enExample) |
| WO (2) | WO2014062733A2 (enExample) |
| ZA (2) | ZA201502526B (enExample) |
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| CA2887243C (en) | 2012-10-15 | 2024-04-09 | Epizyme, Inc. | Methods of treating cancer |
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| TWI627174B (zh) | 2013-03-14 | 2018-06-21 | 比利時商健生藥品公司 | P2x7調控劑 |
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| TWI644671B (zh) | 2013-03-14 | 2018-12-21 | 比利時商健生藥品公司 | P2x7調節劑 |
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| WO2015010049A1 (en) | 2013-07-19 | 2015-01-22 | Epizyme, Inc. | Substituted benzene compounds |
| EP3033334A1 (en) | 2013-08-15 | 2016-06-22 | Constellation Pharmaceuticals, Inc. | Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof |
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| JP6592510B2 (ja) | 2014-09-12 | 2019-10-16 | ヤンセン ファーマシューティカ エヌ.ベー. | P2x7調節因子 |
| EA201790600A1 (ru) | 2014-09-12 | 2017-07-31 | Янссен Фармацевтика Нв | Модулирующие p2x7 n-ацил-триазолопиразины |
| MX394629B (es) * | 2014-10-16 | 2025-03-24 | Epizyme Inc | Método para tratar el cáncer. |
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| EP3236962A2 (en) | 2014-12-23 | 2017-11-01 | University of Copenhagen | Treatment of cancer by inhibiting ezh2 activity |
| MX391720B (es) | 2015-04-20 | 2025-03-21 | Epizyme Inc | Terapia combinada para tratar cáncer. |
| CA2988816A1 (en) * | 2015-06-10 | 2016-12-15 | Epizyme, Inc. | Ezh2 inhibitors for treating lymphoma |
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| CA3039059A1 (en) | 2016-10-19 | 2018-04-26 | Constellation Pharmaceuticals, Inc. | Synthesis of inhibitors of ezh2 |
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| NZ766447A (en) | 2018-01-31 | 2021-12-24 | Mirati Therapeutics Inc | Prc2 inhibitors |
| EP3823671B1 (en) | 2018-07-09 | 2024-02-07 | Fondation Asile Des Aveugles | Inhibition of prc2 subunits to treat eye disorders |
| WO2020065614A1 (en) | 2018-09-28 | 2020-04-02 | Janssen Pharmaceutica Nv | Monoacylglycerol lipase modulators |
| CN113164459B (zh) | 2018-09-28 | 2024-09-03 | 詹森药业有限公司 | 单酰基甘油脂肪酶调节剂 |
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| JP7541538B2 (ja) | 2019-06-05 | 2024-08-28 | ミラティ セラピューティクス,インク. | 癌を処置するためのprc2阻害剤としてのイミダゾ[1,2-c]ピリミジン誘導体 |
| US20220298222A1 (en) | 2019-08-22 | 2022-09-22 | Juno Therapeutics, Inc. | Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods |
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