|
JPS59186924A
(ja)
|
1983-04-08 |
1984-10-23 |
Kureha Chem Ind Co Ltd |
ヒト免疫グロブリン結合抗腫瘍剤
|
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
|
US5395855A
(en)
|
1990-05-07 |
1995-03-07 |
Ciba-Geigy Corporation |
Hydrazones
|
|
US5484612A
(en)
|
1993-09-22 |
1996-01-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
|
|
US6011069A
(en)
|
1995-12-26 |
2000-01-04 |
Nisshin Flour Milling Co., Ltd. |
Multidrug resistance inhibitors
|
|
US20020077461A1
(en)
|
1996-04-24 |
2002-06-20 |
Soren Bjorn |
Pharmaceutical formulation
|
|
ES2263178T3
(es)
|
1996-06-27 |
2006-12-01 |
Chugai Seiyaku Kabushiki Kaisha |
Remedios para mieloma para ser utilizados junto con agentes antitumorales de mostaza nitrogenada.
|
|
US6121245A
(en)
|
1997-01-29 |
2000-09-19 |
Firshein; Richard N. |
Method of treating cancer using alkylglycerols in conjunction with chemotherapy
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US20040072889A1
(en)
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
|
EP1019034A2
(en)
|
1997-07-01 |
2000-07-19 |
Atherogenics, Inc. |
Antioxidant enhancement of therapy for hyperproliferative conditions
|
|
GB9721069D0
(en)
|
1997-10-03 |
1997-12-03 |
Pharmacia & Upjohn Spa |
Polymeric derivatives of camptothecin
|
|
US6100254A
(en)
|
1997-10-10 |
2000-08-08 |
Board Of Regents, The University Of Texas System |
Inhibitors of protein tyrosine kinases
|
|
AU4543899A
(en)
|
1998-06-08 |
1999-12-30 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
|
DE69929440T2
(de)
|
1998-07-09 |
2006-08-17 |
Cephalon, Inc. |
Zusammensetzungen zur behandlung chronischer lymphatischer leukämie
|
|
EP1107964B8
(en)
|
1998-08-11 |
2010-04-07 |
Novartis AG |
Isoquinoline derivatives with angiogenesis inhibiting activity
|
|
US6326390B1
(en)
|
1998-08-25 |
2001-12-04 |
King Pharmaceuticals Reseach And Development, Inc. |
Use of adenosine A3 receptor antagonists to inhibit tumor growth
|
|
EP1165085B1
(en)
|
1999-03-30 |
2006-06-14 |
Novartis AG |
Phthalazine derivatives for treating inflammatory diseases
|
|
US8791081B2
(en)
|
1999-08-13 |
2014-07-29 |
Case Western Reserve University |
MGMT inhibitor combination for the treatment of neoplastic disorders
|
|
US7811981B2
(en)
|
1999-08-30 |
2010-10-12 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Methods of and compositions for inhibiting the proliferation of mammalian cells
|
|
AR030557A1
(es)
|
2000-04-14 |
2003-08-27 |
Jagotec Ag |
Una tableta en multicapa de liberacion controlada y metodo de tratamiento
|
|
EP1160826A3
(en)
|
2000-05-30 |
2006-12-13 |
Ebara Corporation |
Coating, modification and etching of substrate surface with particle beam irradiation
|
|
US20030072794A1
(en)
|
2000-06-09 |
2003-04-17 |
Teni Boulikas |
Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes
|
|
US6613736B2
(en)
|
2000-06-16 |
2003-09-02 |
Thomas T. Aoki |
System and method for treating eye and nerve diseases in diabetic and non-diabetic patients
|
|
ATE465756T1
(de)
|
2000-06-23 |
2010-05-15 |
Mitsubishi Tanabe Pharma Corp |
Antitumoreffekt-verstärker
|
|
AU2001296871A1
(en)
|
2000-09-15 |
2002-03-26 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US7473691B2
(en)
|
2000-09-15 |
2009-01-06 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US6660731B2
(en)
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US6610677B2
(en)
|
2000-09-15 |
2003-08-26 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
CN1116875C
(zh)
|
2000-10-19 |
2003-08-06 |
南京振中生物工程有限公司 |
紫杉醇脂质组合物及其制备方法
|
|
US6503914B1
(en)
|
2000-10-23 |
2003-01-07 |
Board Of Regents, The University Of Texas System |
Thienopyrimidine-based inhibitors of the Src family
|
|
CN101317825A
(zh)
|
2000-10-30 |
2008-12-10 |
欧罗赛铁克股份有限公司 |
控释氢可酮制剂
|
|
US7619005B2
(en)
|
2000-11-01 |
2009-11-17 |
Cognition Pharmaceuticals Llc |
Methods for treating cognitive impairment in humans with Multiple Sclerosis
|
|
US20020155565A1
(en)
|
2000-11-10 |
2002-10-24 |
Pilar Garin-Chesa |
FAP-activated anti-tumor compounds
|
|
HUP0400639A3
(en)
|
2000-12-21 |
2010-03-29 |
Vertex Pharma |
Pyrazole compounds useful as protein kinase inhibitors and pharmaceutical compositions containing them
|
|
US20100098691A1
(en)
|
2001-01-24 |
2010-04-22 |
S'bio Pte Ltd |
Combination of benzimidazole anti-cancer agent and a second anti-cancer agent
|
|
IL159048A0
(en)
|
2001-06-21 |
2004-05-12 |
Genentech Inc |
Sustained release formulation
|
|
US7005445B2
(en)
|
2001-10-22 |
2006-02-28 |
The Research Foundation Of State University Of New York |
Protein kinase and phosphatase inhibitors and methods for designing them
|
|
US20030158118A1
(en)
|
2001-11-26 |
2003-08-21 |
Weidner Morten Sloth |
Combination of cimetidine and cysteine derivatives for treating cancer
|
|
UA76810C2
(uk)
|
2001-12-10 |
2006-09-15 |
Мерк Енд Ко., Інк. |
Фармацевтична композиція антагоніста рецептора тахікініну у формі наночастинок
|
|
US7045534B2
(en)
|
2002-02-12 |
2006-05-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of reducing angiogenesis
|
|
EP2138575B8
(en)
|
2002-02-20 |
2013-07-24 |
Mersana Therapeutics, Inc. |
Conjugates comprising a biodegradable polymer and uses therefor
|
|
US7101576B2
(en)
|
2002-04-12 |
2006-09-05 |
Elan Pharma International Limited |
Nanoparticulate megestrol formulations
|
|
WO2004037814A1
(en)
|
2002-10-25 |
2004-05-06 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
|
TW200413381A
(en)
|
2002-11-04 |
2004-08-01 |
Hoffmann La Roche |
Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
|
|
US7129351B2
(en)
|
2002-11-04 |
2006-10-31 |
Hoffmann-La Roche Inc. |
Pyrimido compounds having antiproliferative activity
|
|
DK2284266T3
(da)
|
2002-11-14 |
2014-01-13 |
Thermo Fisher Scient Biosciences Inc |
sIRNA-MOLEKYLE MOD TP53
|
|
US7276519B2
(en)
|
2002-11-25 |
2007-10-02 |
Wyeth |
Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors
|
|
CL2003002287A1
(es)
|
2002-11-25 |
2005-01-14 |
Wyeth Corp |
COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS
|
|
ATE449081T1
(de)
|
2002-12-30 |
2009-12-15 |
Celgene Corp |
Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen
|
|
DK1603570T5
(da)
|
2003-02-26 |
2013-12-09 |
Sugen Inc |
Aminoheteroarylforbindelser som proteinkinaseinhibitorer
|
|
US20070207952A1
(en)
|
2003-03-24 |
2007-09-06 |
Sequoia Pharmaceuticals |
Long Acting Biologically Active Conjugates
|
|
TW200502236A
(en)
|
2003-03-28 |
2005-01-16 |
Hoffmann La Roche |
Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
|
|
US7220706B1
(en)
|
2003-05-14 |
2007-05-22 |
Praxair S.T. Technology, Inc. |
Enhanced melt-textured growth
|
|
WO2004103958A2
(en)
|
2003-05-19 |
2004-12-02 |
Michigan State University |
Preparation of hymenialdisine derivatives and use thereof
|
|
US7842835B2
(en)
|
2003-07-07 |
2010-11-30 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
|
US20050009891A1
(en)
|
2003-07-09 |
2005-01-13 |
Lee Francis Y. |
Combination of SRC Kinase inhibitors and chemotherapeutic agents for the treatment of proliferative diseases
|
|
AR045731A1
(es)
|
2003-08-06 |
2005-11-09 |
Vertex Pharma |
Compuestos de aminotriazol utiles como inhibidores de quinasas de proteinas
|
|
ES2317047T3
(es)
|
2003-08-07 |
2009-04-16 |
Schering Corporation |
Nuevos inhibidores de la farnesil proteina transferasa como agentes antitumorales.
|
|
CA2540343A1
(en)
|
2003-10-02 |
2005-04-14 |
Cephalon, Inc. |
Indole derivatives
|
|
HUP0303313A2
(hu)
|
2003-10-09 |
2005-07-28 |
Richter Gedeon Vegyészeti Gyár Rt. |
Transzdermális gyógyszerkészítmények
|
|
US7169781B2
(en)
|
2003-10-17 |
2007-01-30 |
Hoffmann-La Roche Inc. |
Imidazole derivatives and their use as pharmaceutical agents
|
|
EP1680119A1
(en)
|
2003-11-06 |
2006-07-19 |
Wyeth |
4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)
|
|
US7491725B2
(en)
|
2004-02-06 |
2009-02-17 |
Bristol-Myers Squibb Company |
Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
|
|
EP1719771A1
(en)
|
2004-02-19 |
2006-11-08 |
Takeda Pharmaceutical Company Limited |
Pyrazoloquinolone derivative and use thereof
|
|
WO2005090344A1
(en)
|
2004-03-15 |
2005-09-29 |
F. Hoffmann-La Roche Ag |
Novel dichloro-phenyl-pyrido [2,3-d] pyrimidine derivates, their manufacture and use as pharmaceutical agents
|
|
WO2005092326A1
(en)
|
2004-03-22 |
2005-10-06 |
The Regents Of The University Of Michigan |
Small molecule antagonists of xiap family proteins
|
|
JP4993374B2
(ja)
|
2004-04-05 |
2012-08-08 |
メルク エイチディーエーシー リサーチ エルエルシー |
ヒストン脱アセチル化酵素インヒビタープロドラッグ
|
|
TW200538149A
(en)
|
2004-05-20 |
2005-12-01 |
Telik Inc |
Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
|
|
TW200600091A
(en)
|
2004-05-21 |
2006-01-01 |
Telik Inc |
Sulfonylethyl phosphorodiamidates
|
|
AU2005269716B2
(en)
|
2004-07-20 |
2011-01-27 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
|
US7479561B2
(en)
|
2004-08-16 |
2009-01-20 |
Wyeth |
4-(2,4-dichloro-5-methoxyphenyl)amino-6-methoxy-7-{[5-substituted-amino)methyl]-3-furyl}-3-quinolinecarbonitriles as kinase inhibitors
|
|
KR100853974B1
(ko)
|
2004-08-31 |
2008-08-25 |
에프. 호프만-라 로슈 아게 |
7-아미노-3-페닐 디히드로피리미도[4,5-ｄ]피리미디논의아미드 유도체, 그의 제조 방법 및 약학제로서의 용도
|
|
WO2006031806A2
(en)
|
2004-09-10 |
2006-03-23 |
Atherogenics, Inc. |
2-thiopyrimidinones as therapeutic agents
|
|
CN101014600A
(zh)
|
2004-09-21 |
2007-08-08 |
霍夫曼-拉罗奇有限公司 |
用作蛋白激酶抑制剂的6－(2－烷基－苯基)－吡啶并[2,3－d]嘧啶类
|
|
US7355677B2
(en)
|
2004-12-09 |
2008-04-08 |
Asml Netherlands B.V. |
System and method for an improved illumination system in a lithographic apparatus
|
|
AR054416A1
(es)
|
2004-12-22 |
2007-06-27 |
Incyte Corp |
Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas.
|
|
EP1833829A2
(en)
|
2004-12-23 |
2007-09-19 |
F. Hoffmann-Roche AG |
Benzamide substituted imidazo- and pyrrolo-pyridines as protein kinase inhibitors
|
|
US7786113B2
(en)
|
2004-12-23 |
2010-08-31 |
Hoffman-La Roche Inc. |
Heterocyclic carbamate derivatives, their manufacture and use as pharmaceutical agents
|
|
US7968574B2
(en)
|
2004-12-28 |
2011-06-28 |
Kinex Pharmaceuticals, Llc |
Biaryl compositions and methods for modulating a kinase cascade
|
|
CN101142198B
(zh)
|
2005-02-17 |
2012-10-31 |
辛塔制药公司 |
用于治疗疾病的异*唑坎布雷它斯丁衍生物
|
|
US20060229277A1
(en)
|
2005-04-08 |
2006-10-12 |
Orbus Pharma, Inc. |
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
|
|
US8242103B2
(en)
|
2005-05-19 |
2012-08-14 |
Merck Sharp & Dohme Limited |
Sulphamides for treatment of cancer
|
|
ES2392544T3
(es)
|
2005-06-07 |
2012-12-11 |
Yale University |
Métodos de tratamiento del cáncer y otras enfermedades o estados patológicos usando LFMAU y LDT
|
|
BRPI0612138B8
(pt)
|
2005-06-15 |
2021-05-25 |
Cardiome Pharma Corp |
compostos éter aminocicloexílicos e método para fazer os mesmos
|
|
HRP20110804T1
(hr)
|
2005-06-23 |
2011-11-30 |
Merck Sharp & Dohme Corp. |
Benzocikloheptapiridini kao inhibitori receptora tirozin kinaze met
|
|
PT3248613T
(pt)
|
2005-07-18 |
2022-03-16 |
Seagen Inc |
Conjugados de ligante de fármaco e beta-glucuronida
|
|
US7776878B2
(en)
|
2005-08-01 |
2010-08-17 |
Hoffmann-La Roche Inc. |
Heterocyclic benzylamino derivatives, their manufacture and use as pharmaceutical agents
|
|
US7700773B2
(en)
|
2005-09-09 |
2010-04-20 |
Schering Corporation |
4-cyano, 4-amino, and 4-aminomethyl derivatives of pyrazolo[1,5-a]pyridines, pyrazolo[1,5-c]pyrimidines and 2H-indazole compounds and 5-cyano, 5-amino, and 5-aminomethyl derivatives of imidazo[1,2-a]pyridines, and imidazo[1,5-a]pyrazines as cyclin dependent kinase inhibitors
|
|
CA2626016A1
(en)
|
2005-10-21 |
2007-06-21 |
Panacea Biotec Limited |
Pharmaceutical composition comprising at least one anticancer drug and at least one polymer
|
|
MY167260A
(en)
|
2005-11-01 |
2018-08-14 |
Targegen Inc |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
CN101316597B
(zh)
|
2005-11-03 |
2013-04-17 |
顶点医药品公司 |
用作激酶抑制剂的氨基嘧啶
|
|
EP1948132B1
(en)
|
2005-11-18 |
2009-08-05 |
Synhton B.V. |
Zolpidem tablets
|
|
KR101391900B1
(ko)
|
2005-12-13 |
2014-05-02 |
인사이트 코포레이션 |
야누스 키나아제 억제제로서의 헤테로아릴 치환된 피롤로［2,3-ｂ］피리딘 및 피롤로［2,3-ｂ］피리미딘
|
|
US8014957B2
(en)
*
|
2005-12-15 |
2011-09-06 |
Fred Hutchinson Cancer Research Center |
Genes associated with progression and response in chronic myeloid leukemia and uses thereof
|
|
WO2007081751A2
(en)
|
2006-01-05 |
2007-07-19 |
The Johns Hopkins University |
Compositions and methods for the treatment of cancer
|
|
ES2329419T3
(es)
|
2006-01-31 |
2009-11-25 |
F. Hoffmann-La Roche Ag |
7h-pirido(3,4-d)pirimidin-8-onas, su preparacion y uso como inhibidores de proteinas cinasas.
|
|
EP2001400B1
(en)
|
2006-03-14 |
2014-05-07 |
Neuren Pharmaceuticals Limited |
Oral formulations of glycyl-2-methylprolyl-glutamate
|
|
JP2009531364A
(ja)
|
2006-03-28 |
2009-09-03 |
ノバルティス アクチエンゲゼルシャフト |
アミド誘導体およびｇタンパク質関連疾患の処置のためのそれらの使用
|
|
CN101415409B
(zh)
|
2006-04-05 |
2012-12-05 |
诺瓦提斯公司 |
用于治疗癌症的治疗剂的组合
|
|
CA2649861A1
(en)
|
2006-04-26 |
2007-11-08 |
Merck & Co., Inc. |
Disubstituted aniline compounds
|
|
US8299052B2
(en)
|
2006-05-05 |
2012-10-30 |
Shionogi Inc. |
Pharmaceutical compositions and methods for improved bacterial eradication
|
|
GB0609378D0
(en)
|
2006-05-11 |
2006-06-21 |
Novartis Ag |
Organic compounds
|
|
US7964728B2
(en)
|
2006-07-06 |
2011-06-21 |
Solvay Pharmaceuticals B.V. |
Azaindole derivatives with a combination of partial nicotinic acetyl-choline receptor agonism and dopamine reuptake inhibition
|
|
TW200813021A
(en)
|
2006-07-10 |
2008-03-16 |
Merck & Co Inc |
Tyrosine kinase inhibitors
|
|
WO2008009407A2
(en)
|
2006-07-17 |
2008-01-24 |
Novartis Ag |
Sulphonylaminocarbonyl derivatives of bile acid amides for use as immunomodulators
|
|
US8080252B2
(en)
|
2006-07-19 |
2011-12-20 |
The Cleveland Clinic Foundation |
Compounds and methods of modulating angiogenesis
|
|
EP2049563B1
(en)
|
2006-07-24 |
2014-03-12 |
Tetralogic Pharmaceuticals Corporation |
Dimeric iap antagonists
|
|
US7683060B2
(en)
|
2006-08-07 |
2010-03-23 |
Incyte Corporation |
Triazolotriazines as kinase inhibitors
|
|
JP2010500370A
(ja)
|
2006-08-07 |
2010-01-07 |
ピーディーエル バイオファーマ，インコーポレイティド |
多発性硬化症を処置するための抗ｃｓ１抗体を用いる組成物および方法
|
|
CA2659425C
(en)
|
2006-08-17 |
2017-06-20 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
|
RU2009110243A
(ru)
|
2006-08-23 |
2010-09-27 |
Новартис АГ (CH) |
Амиды как ингибиторы сфингомиелина
|
|
US8222288B2
(en)
|
2006-08-30 |
2012-07-17 |
The Regents Of The University Of Michigan |
Small molecule inhibitors of MDM2 and the uses thereof
|
|
US7956064B2
(en)
|
2006-09-01 |
2011-06-07 |
Cylene Pharmaceuticals, Inc. |
Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
|
|
AU2007292387A1
(en)
|
2006-09-05 |
2008-03-13 |
Bipar Sciences, Inc. |
Treatment of cancer
|
|
WO2008030408A2
(en)
|
2006-09-05 |
2008-03-13 |
Yale University |
Proteomimetic compounds as inhibitors of the interaction of a nuclear receptor with coactivator peptides
|
|
US8242080B2
(en)
|
2006-10-13 |
2012-08-14 |
The Regents Of The University Of California |
Inhibitors of the EGFR kinase targeting the asymmetric activating dimer interface
|
|
CN101573345A
(zh)
|
2006-10-31 |
2009-11-04 |
先灵公司 |
作为蛋白激酶抑制剂的2-氨基噻唑-4-甲酰胺
|
|
US8283441B2
(en)
|
2006-10-31 |
2012-10-09 |
University Of Toledo |
Na+K+-ATPase-specific peptide inhibitors/activators of SRC and SRC family kinases
|
|
CA2667487C
(en)
|
2006-11-06 |
2017-04-04 |
Supergen, Inc. |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
|
US20120164075A1
(en)
|
2006-11-21 |
2012-06-28 |
Jina Pharmaceuticals, Inc. |
Endoxifen methods and compositions in the treatment of mammalian diseases
|
|
US20080125397A1
(en)
|
2006-11-28 |
2008-05-29 |
Telik, Inc. |
2 (SULFONYL)ETHYL N,N,N',N' tetrakis(2 chloroethyl)phosphorodia
|
|
US7655799B2
(en)
|
2006-11-29 |
2010-02-02 |
Telik, Inc. |
2{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidates
|
|
EP2101571B1
(en)
|
2006-12-11 |
2011-05-18 |
Kempharm, Inc. |
Ornithine conjugates of amphetamine and processes for making and using the same
|
|
EP1932820A1
(en)
|
2006-12-14 |
2008-06-18 |
Bp Oil International Limited |
Process for manufacturing neohexene
|
|
US7956216B2
(en)
*
|
2006-12-21 |
2011-06-07 |
The Walter And Eliza Hall Institute Of Medical Research |
Alpha-helical mimetics
|
|
WO2008079973A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Egfr binding peptides and uses thereof
|
|
US8834920B2
(en)
|
2006-12-21 |
2014-09-16 |
Alza Corporation |
Liposome composition for targeting egfr receptor
|
|
US20080293648A1
(en)
|
2007-01-05 |
2008-11-27 |
Saha Pharmaceuticals, Inc. |
Compositions and Methods for Cancer Treatment
|
|
CA2676145A1
(en)
|
2007-02-06 |
2008-08-14 |
Novartis Ag |
1-benzenesulfonyl-1h-indole derivatives as inhibitors of ccr9 activity
|
|
EP2491923A3
(en)
|
2007-02-15 |
2012-12-26 |
Novartis AG |
Combinations of therapeutic agents for treating cancer
|
|
CA2783589A1
(en)
|
2007-03-09 |
2008-09-18 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
|
WO2008112277A2
(en)
|
2007-03-13 |
2008-09-18 |
Wake Forest University |
Compositions and methods for treating cancer
|
|
ES2430614T3
(es)
|
2007-04-10 |
2013-11-21 |
Exelixis, Inc. |
Métodos de tratamiento del cáncer usando inhibidores de piridopirimidinona de PI3K alfa
|
|
BRPI0810195A2
(pt)
|
2007-04-13 |
2014-12-30 |
Novartis Ag |
Moduladores de gpbar1
|
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
|
US7838495B2
(en)
|
2007-04-27 |
2010-11-23 |
University Of Maryland, Baltimore |
Compositions and methods of use of EPB1, and ErbB3 binding protein
|
|
JP5389785B2
(ja)
|
2007-05-02 |
2014-01-15 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼ阻害剤として有用なチアゾールおよびピラゾール
|
|
WO2008144506A1
(en)
|
2007-05-16 |
2008-11-27 |
University Of Maryland, Baltimore |
Apoptotic pathway targeting for the diagnosis and treatment of cancer
|
|
US8367078B2
(en)
|
2007-06-06 |
2013-02-05 |
University Of Florida Research Foundation, Inc. |
Kinase inhibitor compounds
|
|
US20110288023A1
(en)
|
2007-06-08 |
2011-11-24 |
The Regents Of The University Of California Office Of Technology Transfer |
Cancer drug delivery using modified transferrin
|
|
WO2009003911A1
(en)
|
2007-06-29 |
2009-01-08 |
4Sc Ag |
Thiophene-imidazopyridines
|
|
JP2010532756A
(ja)
|
2007-07-06 |
2010-10-14 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
ｍＴＯＲＣ１及びｍＴＯＲＣ２の両方の阻害剤を含む組み合わせ抗癌療法
|
|
KR20100053607A
(ko)
|
2007-08-03 |
2010-05-20 |
패시트 바이오테크 코포레이션 |
항-ｔｗｅａｋ 수용체 항체의 치료 용도
|
|
HUE027443T2
(en)
|
2007-09-10 |
2016-10-28 |
Boston Biomedical Inc |
A novel class of Stat3 pathway inhibitors and tumor stem cell inhibitors
|
|
WO2009045504A1
(en)
|
2007-10-04 |
2009-04-09 |
President And Fellows Of Harvard College |
Methods and compositions for treating cancer and modulating signal transduction and metabolism pathways
|
|
CN101903403B
(zh)
|
2007-10-19 |
2016-03-16 |
西雅图基因公司 |
Cd19结合剂及其应用
|
|
WO2009054941A1
(en)
|
2007-10-25 |
2009-04-30 |
Merck & Co., Inc. |
Therapeutic compounds
|
|
SI2215094T1
(sl)
|
2007-11-15 |
2016-05-31 |
Ym Biosciences Australia Pty Ltd |
N vsebujoče heterociklične spojine
|
|
US8268827B2
(en)
|
2007-11-15 |
2012-09-18 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa. |
Pyridazinone derivatives as PARP inhibitors
|
|
CN101910152B
(zh)
|
2007-11-16 |
2014-08-06 |
因塞特公司 |
作为janus激酶抑制剂的4-吡唑基-n-芳基嘧啶-2-胺和4-吡唑基-n-杂芳基嘧啶-2-胺
|
|
CN101444490A
(zh)
*
|
2007-11-26 |
2009-06-03 |
天津市金圭谷木糖醇有限公司 |
一种含脱水卫矛醇经注射给药的制剂及其制备方法
|
|
CN101450100A
(zh)
*
|
2007-11-28 |
2009-06-10 |
天津金世制药有限公司 |
一种治疗急慢性粒细胞白血病的药物组合物
|
|
US8088749B2
(en)
|
2007-12-12 |
2012-01-03 |
The Regents Of The University Of Michigan |
Compositions and methods for treating cancer
|
|
WO2009082662A1
(en)
|
2007-12-21 |
2009-07-02 |
Novartis Ag |
Combination of nilotinib and a nitrogen mustard analogue for the treatment of chronic lymphocytic leukemia
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
WO2009099677A2
(en)
*
|
2008-02-08 |
2009-08-13 |
Aileron Therapeutics, Inc. |
Therapeutic peptidomimetic macrocycles
|
|
WO2009102707A2
(en)
|
2008-02-11 |
2009-08-20 |
Auspex Pharmaceuticals, Inc. |
Substituted oxazaphosphorines
|
|
US20090209340A1
(en)
|
2008-02-14 |
2009-08-20 |
Aruze Gaming America, Inc. |
Gaming Apparatus Capable of Conversation with Player and Control Method Thereof
|
|
EP2259791A2
(en)
|
2008-03-05 |
2010-12-15 |
Tel HaShomer Medical Research Infrastructure and Services Ltd. |
Glp-1 receptor agonists and related active pharmaceutical ingredients for treatment of cancer
|
|
MX2010010012A
(es)
|
2008-03-11 |
2010-10-20 |
Incyte Corp |
Derivados de azetidina y ciclobutano como inhibidores de jak.
|
|
EP2110377A1
(en)
|
2008-04-15 |
2009-10-21 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
CN102076717B
(zh)
|
2008-04-30 |
2016-02-03 |
伊缪诺金公司 |
交联剂和它们的用途
|
|
WO2009143018A2
(en)
|
2008-05-19 |
2009-11-26 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
US8207169B2
(en)
|
2008-06-03 |
2012-06-26 |
Msd K.K. |
Substituted [1,2,4]triazolo[4′,3′:1,6]pyrido[2,3-b]pyrazines of the formula D
|
|
GB2460672B
(en)
|
2008-06-04 |
2012-01-04 |
Gw Pharma Ltd |
Cannabinoids in combination with non-cannabinoid chemotherapeutic agents that are alkylating agents
|
|
EP2133334A1
(en)
|
2008-06-09 |
2009-12-16 |
DAC S.r.l. |
Heterocyclic derivatives as HDAC inhibitors
|
|
DK2310011T3
(da)
*
|
2008-06-17 |
2013-10-14 |
Wyeth Llc |
Antineoplastiske kombinationer indeholdende hki-272 og vinorelbin
|
|
US8207195B2
(en)
|
2008-06-26 |
2012-06-26 |
Inspire Pharmaceuticals, Inc. |
Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds
|
|
SG192485A1
(en)
|
2008-07-08 |
2013-08-30 |
Incyte Corp |
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
|
|
US8217076B2
(en)
|
2008-07-17 |
2012-07-10 |
Colorado State University Research Foundation |
Method for preparing largazole analogs and uses thereof
|
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
|
US20120230991A1
(en)
|
2008-07-29 |
2012-09-13 |
Douglas Kim Graham |
Methods and compounds for enhancing anti-cancer therapy
|
|
WO2010021822A2
(en)
|
2008-07-30 |
2010-02-25 |
The Regents Of The University Of California |
Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites
|
|
WO2010014913A1
(en)
|
2008-08-01 |
2010-02-04 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
NZ591113A
(en)
|
2008-08-26 |
2012-07-27 |
Boehringer Ingelheim Int |
Thienopyrimidine linked to phenyl or pyridine via an nh amine for pharmaceutical compositions
|
|
US20100068302A1
(en)
|
2008-09-17 |
2010-03-18 |
Traslational Cancer Drugs Pharma, S.L. |
Methods and compositions for the treatment of cancer
|
|
US20100111901A1
(en)
|
2008-11-03 |
2010-05-06 |
Auspex Pharmaceuticals, Inc. |
Triazole inhibitors of aromatase
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
NZ593937A
(en)
|
2008-12-08 |
2014-05-30 |
Vm Pharma Llc |
Compositions of protein receptor tyrosine kinase inhibitors
|
|
WO2010068920A2
(en)
|
2008-12-12 |
2010-06-17 |
Auspex Pharmaceutical, Inc. |
Diaminoquinazoline inhibitors of dihydrofolate reductase
|
|
PA8851101A1
(es)
|
2008-12-16 |
2010-07-27 |
Lilly Co Eli |
Compuesto amino pirazol
|
|
WO2010080570A2
(en)
|
2008-12-18 |
2010-07-15 |
New York University |
Tumor therapy with antitumor agents in combination with sindbis virus-based vectors
|
|
US20100173013A1
(en)
|
2009-01-08 |
2010-07-08 |
Denis Drygin |
Treatment of neoplastic disorders using combination therapies
|
|
WO2010091140A1
(en)
*
|
2009-02-04 |
2010-08-12 |
Bipar Sciences, Inc. |
Treatment of lung cancer with a parp inhibitor in combination with a growth factor inhibitor
|
|
CN104523661A
(zh)
|
2009-02-06 |
2015-04-22 |
南加利福尼亚大学 |
含有单萜的治疗组合物
|
|
RU2011141123A
(ru)
|
2009-03-11 |
2013-04-20 |
Плексксикон, Инк. |
ПРОИЗВОДНЫЕ ПИРРОЛО[2,3-b]ПИРИДИНА В КАЧЕСТВЕ ИНГИБИТОРОВ RAF-КИНАЗ
|
|
EP2413901A4
(en)
|
2009-03-30 |
2015-05-06 |
Cerulean Pharma Inc |
POLYMER CONCRETE CONJUGATES, PARTICLES, COMPOSITIONS AND CORRESPONDING USES
|
|
WO2010114805A1
(en)
|
2009-03-31 |
2010-10-07 |
The Trustees Of The University Of Pennsylvania |
Methods of treating cancer with phenformin
|
|
US8680139B2
(en)
|
2009-04-01 |
2014-03-25 |
Progenra |
Anti-neoplastic compounds, compositions and methods
|
|
EP2417123A2
(en)
|
2009-04-06 |
2012-02-15 |
Agios Pharmaceuticals, Inc. |
Therapeutic compositions and related methods of use
|
|
US20100291025A1
(en)
|
2009-04-13 |
2010-11-18 |
Auspex Pharmaceuticals, Inc. |
Indazole inhibitors of tyrosine kinase
|
|
US20110053968A1
(en)
|
2009-06-09 |
2011-03-03 |
Auspex Pharmaceuticals, Inc. |
Aminopyrimidine inhibitors of tyrosine kinase
|
|
US9151762B2
(en)
|
2009-06-12 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Identification of DSG-3 as a biomarker for the detection of metastasis in lymph nodes
|
|
US8232318B2
(en)
|
2009-07-31 |
2012-07-31 |
The General Hospital Corporation |
Approaches to treat cancer using HB-EGF inhibitors
|
|
EP2470546B1
(en)
|
2009-08-28 |
2013-07-24 |
Takeda Pharmaceutical Company Limited |
Hexahydrooxazinopteridine compounds for use as mtor inhibitors
|
|
CN102625803A
(zh)
|
2009-09-11 |
2012-08-01 |
赛林药物股份有限公司 |
药学上有用的杂环-取代的内酰胺
|
|
BR112012005970A2
(pt)
|
2009-09-16 |
2015-09-08 |
Cylene Pharmaceuticals Inc |
moduladores tricíclicos de proteína quinase
|
|
ES2444779T3
(es)
|
2009-09-28 |
2014-02-26 |
F. Hoffmann-La Roche Ag |
Compuestos de benzoxazepina inhibidores de la PI3K y su utilización en el tratamiento de cáncer
|
|
US8304577B2
(en)
|
2009-10-09 |
2012-11-06 |
Bristol-Myers Squibb Company |
Modulators of G protein-coupled receptor 88
|
|
MY174452A
(en)
*
|
2009-10-14 |
2020-04-19 |
Schering Corp |
Substituted piperidines that increase p53 activity and the uses thereof
|
|
WO2011050242A1
(en)
|
2009-10-23 |
2011-04-28 |
Millennium Pharmaceuticals, Inc. |
Anti-gcc antibody molecules and related compositions and methods
|
|
JP5802676B2
(ja)
|
2009-12-04 |
2015-10-28 |
センワ バイオサイエンシズ インコーポレイテッド |
Ｃｋ２阻害剤としてのピラゾロピリミジンおよび関連複素環化合物
|
|
US8445517B2
(en)
|
2009-12-11 |
2013-05-21 |
Dana-Farber Cancer Institute |
Stat modulators
|
|
US20110195066A1
(en)
|
2010-02-05 |
2011-08-11 |
Auspex Pharmaceuticals, Inc. |
Quinoline inhibitors of tyrosine kinase
|
|
US20110206661A1
(en)
|
2010-02-24 |
2011-08-25 |
Auspex Pharmaceuticals, Inc. |
Trimethoxyphenyl inhibitors of tyrosine kinase
|
|
UY33241A
(es)
|
2010-02-26 |
2011-09-30 |
Boehringer Ingelheim Int |
?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
|
|
AR080328A1
(es)
|
2010-02-26 |
2012-03-28 |
Boehringer Ingelheim Int |
Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros
|
|
CN103002742B
(zh)
|
2010-03-05 |
2016-07-13 |
卡尔约药物治疗公司 |
核转运调节剂及其应用
|
|
US8389525B2
(en)
|
2010-05-05 |
2013-03-05 |
Renee Desai |
Small molecules for inhibition of protein kinases
|
|
WO2011143422A1
(en)
|
2010-05-12 |
2011-11-17 |
Vertex Pharmaceuticals Incorporated |
2 -aminopyridine derivatives useful as inhibitors of atr kinase
|
|
MX2012012992A
(es)
*
|
2010-05-14 |
2012-12-17 |
Genentech Inc |
Metodos de tratamiento.
|
|
US8846707B2
(en)
*
|
2010-08-02 |
2014-09-30 |
Univeristy Of Central Florida Research Foundation, Inc. |
Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of stat protein
|
|
EP2605650A4
(en)
*
|
2010-08-18 |
2014-05-21 |
Del Mar Pharmaceuticals |
COMPOSITIONS AND METHODS FOR INCREASING THE THERAPEUTIC UTILITY OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS INCLUDING SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL AND DIACETYL DIANHYDROGALACTITOL
|
|
US9029103B2
(en)
*
|
2010-08-27 |
2015-05-12 |
Illumina Cambridge Limited |
Methods for sequencing polynucleotides
|
|
WO2012044832A1
(en)
|
2010-09-30 |
2012-04-05 |
Fetzer Oliver S |
Methods of treating a subject and related particles, polymers and compositions
|
|
CN103298474B
(zh)
|
2010-11-10 |
2016-06-29 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
SG182016A1
(en)
*
|
2010-12-14 |
2012-07-30 |
Univ Singapore |
Method of detecting resistance to cancer therapy
|
|
US20150087687A1
(en)
*
|
2012-03-23 |
2015-03-26 |
Dennis Brown |
Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo
|
|
US9814693B2
(en)
*
|
2012-05-09 |
2017-11-14 |
Delmar Pharmaceuticals, Inc. |
Veterinary use of dianhydrogalactitol, diacetyldianhydrogalactitol, and dibromodulcitol to treat malignancies
|
|
US8729286B2
(en)
*
|
2012-05-10 |
2014-05-20 |
Massachusetts Institute Of Technology |
Platinum compounds as treatment for cancers, and related methods, kits, and compositions
|