AU2013280644B2 - Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof - Google Patents
Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof Download PDFInfo
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Landscapes
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| US20160067241A1 (en) * | 2013-06-13 | 2016-03-10 | Dennis M. Brown | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted naphthalimides such as amonafide for the treatment of immunological, metabolic, infectious, and benign or neoplastic hyperproliferative disease conditions |
| KR102384740B1 (ko) | 2013-12-27 | 2022-04-07 | 자임워크스 인코포레이티드 | 약물 접합체를 위한 설폰아마이드-함유 연결 시스템 |
| BR112016015105A8 (pt) | 2013-12-27 | 2018-04-24 | Var2 Pharmaceuticals Aps | conjugados var2csa-droga |
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| EP3125920B1 (en) * | 2014-04-04 | 2020-12-23 | Del Mar Pharmaceuticals | Dianhydrogalactitol, diacetyldianhydrogalactitol or dibromodulcitol to treat non-small-cell carcinoma of the lung and ovarian cancer |
| JP2017523207A (ja) * | 2014-08-08 | 2017-08-17 | ファーマサイクリックス エルエルシー | ブルトン型チロシンキナーゼ阻害薬の組み合わせ及びそれらの使用 |
| RS62860B1 (sr) | 2014-09-17 | 2022-02-28 | Zymeworks Inc | Citotoksična i antimitotička jedinjenja, i postupci upotrebe istih |
| CN108024987A (zh) * | 2014-10-10 | 2018-05-11 | 德玛医药 | 用于治疗癌症的二去水卫矛醇的类似物或衍生物与含铂抗肿瘤药物的组合 |
| WO2016059590A1 (en) * | 2014-10-16 | 2016-04-21 | Piramal Enterprises Limited | Stable injectable composition of small molecule drugs and process for its preparation |
| CN108137514A (zh) * | 2015-07-30 | 2018-06-08 | 百时美施贵宝公司 | 芳基取代的二环杂芳基化合物 |
| TW201726130A (zh) * | 2015-10-02 | 2017-08-01 | 基利科學股份有限公司 | 用於治療癌症之組合療法 |
| WO2017075052A1 (en) * | 2015-10-28 | 2017-05-04 | Delmar Pharmaceuticals, Inc. | Use of dianhydrogalactitol or derivatives or analogs thereof for treatment of pediatric central nervous system malignancies |
| CN105476996B (zh) * | 2015-12-21 | 2017-12-26 | 神威药业集团有限公司 | 姜黄素与阿法替尼联合治疗非小细胞肺癌的用途 |
| CN105663028B (zh) * | 2016-02-23 | 2018-10-30 | 广西梧州制药（集团）股份有限公司 | 一种含去水卫矛醇的经直肠给药双层缓释栓剂 |
| CN105663075B (zh) * | 2016-02-23 | 2018-09-14 | 广西梧州制药（集团）股份有限公司 | 一种二溴卫矛醇肠溶片及其制备方法 |
| US10517958B2 (en) | 2016-10-04 | 2019-12-31 | Zymeworks Inc. | Compositions and methods for the treatment of platinum-drug resistant cancer |
| EP3549608A4 (en) | 2016-12-01 | 2020-08-12 | Jiangsu Hengrui Medicine Co., Ltd. | USE OF A COMBINATION OF A VEGFR INHIBITOR AND PARP INHIBITOR IN THE MANUFACTURING OF A MEDICINAL PRODUCT FOR TREATMENT OF STOMACH CANCER |
| WO2018100381A1 (en) * | 2016-12-01 | 2018-06-07 | Oxford Biodynamics Limited | Application of epigenetic chromsomal interactions in cancer diagnostics |
| US10617693B2 (en) | 2017-03-10 | 2020-04-14 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
| US20200031920A1 (en) * | 2017-04-04 | 2020-01-30 | The George Washington University | Combination Therapy for Treating Cancer |
| EP3721906A4 (en) | 2017-12-06 | 2021-08-04 | Jiangsu Hengrui Medicine Co., Ltd. | USE OF PARP INHIBITOR TO TREAT CHEMOTHERAPY RESISTANT OVAR CANCER OR BREAST CANCER |
| KR20190106315A (ko) * | 2018-03-08 | 2019-09-18 | 고려대학교 산학협력단 | 비소세포폐암의 표피성장인자 수용체 표적 항암제에 대한 민감성 증진용 조성물 |
| CN112135825A (zh) | 2018-03-13 | 2020-12-25 | 夏尔人类遗传性治疗公司 | 血浆激肽释放酶抑制剂及其用途 |
| CN108653293B (zh) * | 2018-05-29 | 2020-08-11 | 复旦大学 | Jak2抑制剂在预防和治疗印戒细胞癌中的应用 |
| WO2020200291A1 (en) * | 2019-04-02 | 2020-10-08 | Cullgen (Shanghai) , Inc. | Compounds and methods of treating cancers |
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| JP7695232B2 (ja) | 2019-09-18 | 2025-06-18 | 武田薬品工業株式会社 | ヘテロアリール血漿カリクレインインヒビター |
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| BR112022008683A2 (pt) | 2019-11-05 | 2022-07-19 | Abbvie Inc | Regimes de dosagem para uso no tratamento de mielofibrose e distúrbios relacionados a mpn com navitoclax |
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| US20150182490A1 (en) | 2015-07-02 |
| WO2014004376A3 (en) | 2014-03-27 |
| CN104797267A (zh) | 2015-07-22 |
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| WO2014004376A2 (en) | 2014-01-03 |
| KR20150034209A (ko) | 2015-04-02 |
| JP2015526410A (ja) | 2015-09-10 |
| AU2018256477A1 (en) | 2018-11-22 |
| KR20210138132A (ko) | 2021-11-18 |
| BR112014032346A2 (pt) | 2017-06-27 |
| AU2013280644A1 (en) | 2015-01-22 |
| SG10201610869TA (en) | 2017-02-27 |
| EP2872161B1 (en) | 2020-12-16 |
| EP2872161A4 (en) | 2016-07-20 |
| CL2014003526A1 (es) | 2015-08-28 |
| CN112755193A (zh) | 2021-05-07 |
| JP2018087205A (ja) | 2018-06-07 |
| EP2872161A2 (en) | 2015-05-20 |
| CA2880896C (en) | 2021-11-16 |
| MX2014015795A (es) | 2015-10-14 |
| IL236470A0 (en) | 2015-02-26 |
| SG11201408679XA (en) | 2015-01-29 |
| CA2880896A1 (en) | 2014-01-03 |
| JP6280546B2 (ja) | 2018-02-14 |
| KR102427777B1 (ko) | 2022-08-01 |
| MX367055B (es) | 2019-08-02 |
| IL236470B (en) | 2019-06-30 |
| SG10201805807PA (en) | 2018-08-30 |
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