JP6280546B2 - ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 - Google Patents

ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 Download PDF

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JP6280546B2
JP6280546B2 JP2015520365A JP2015520365A JP6280546B2 JP 6280546 B2 JP6280546 B2 JP 6280546B2 JP 2015520365 A JP2015520365 A JP 2015520365A JP 2015520365 A JP2015520365 A JP 2015520365A JP 6280546 B2 JP6280546 B2 JP 6280546B2
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inhibitor
phenyl
kinase
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tki
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JP2015526410A5 (enExample
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エム. ブラウン、デニス
エム. ブラウン、デニス
エイ. バシャ、ジェフリー
エイ. バシャ、ジェフリー
ジェイ. ガーナー、ウィリアム
ジェイ. ガーナー、ウィリアム
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デル マー ファーマシューティカルズ
デル マー ファーマシューティカルズ
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2015520365A 2012-06-26 2013-06-24 ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 Expired - Fee Related JP6280546B2 (ja)

Applications Claiming Priority (5)

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US201261664279P 2012-06-26 2012-06-26
US61/664,279 2012-06-26
US201361824672P 2013-05-17 2013-05-17
US61/824,672 2013-05-17
PCT/US2013/047320 WO2014004376A2 (en) 2012-06-26 2013-06-24 Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or ahi1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof

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JP2018007222A Division JP2018087205A (ja) 2012-06-26 2018-01-19 ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法

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JP2015526410A5 JP2015526410A5 (enExample) 2016-08-12
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JP2015520365A Expired - Fee Related JP6280546B2 (ja) 2012-06-26 2013-06-24 ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
JP2018007222A Pending JP2018087205A (ja) 2012-06-26 2018-01-19 ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法

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US (2) US20150182490A1 (enExample)
EP (1) EP2872161B1 (enExample)
JP (2) JP6280546B2 (enExample)
KR (2) KR102427777B1 (enExample)
CN (2) CN112755193A (enExample)
AU (2) AU2013280644B2 (enExample)
BR (1) BR112014032346A2 (enExample)
CA (1) CA2880896C (enExample)
CL (1) CL2014003526A1 (enExample)
IL (1) IL236470B (enExample)
MX (1) MX367055B (enExample)
SG (3) SG10201805807PA (enExample)
WO (1) WO2014004376A2 (enExample)

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