JPS59186924A
(ja)
|
1983-04-08 |
1984-10-23 |
Kureha Chem Ind Co Ltd |
ヒト免疫グロブリン結合抗腫瘍剤
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
US5395855A
(en)
|
1990-05-07 |
1995-03-07 |
Ciba-Geigy Corporation |
Hydrazones
|
US5484612A
(en)
|
1993-09-22 |
1996-01-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
|
US6011069A
(en)
|
1995-12-26 |
2000-01-04 |
Nisshin Flour Milling Co., Ltd. |
Multidrug resistance inhibitors
|
US20020077461A1
(en)
|
1996-04-24 |
2002-06-20 |
Soren Bjorn |
Pharmaceutical formulation
|
ATE326238T1
(de)
|
1996-06-27 |
2006-06-15 |
Chugai Pharmaceutical Co Ltd |
Mittel gegen myelome, welches zusammen mit antitumorwirkstoffen auf der basis von stickstoff-senfgasen verwendet werden kann
|
US6121245A
(en)
|
1997-01-29 |
2000-09-19 |
Firshein; Richard N. |
Method of treating cancer using alkylglycerols in conjunction with chemotherapy
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
US20040072889A1
(en)
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
WO1999001118A2
(en)
|
1997-07-01 |
1999-01-14 |
Atherogenics, Inc. |
Antioxidant enhancement of therapy for hyperproliferative conditions
|
GB9721069D0
(en)
|
1997-10-03 |
1997-12-03 |
Pharmacia & Upjohn Spa |
Polymeric derivatives of camptothecin
|
US6100254A
(en)
|
1997-10-10 |
2000-08-08 |
Board Of Regents, The University Of Texas System |
Inhibitors of protein tyrosine kinases
|
AU4543899A
(en)
|
1998-06-08 |
1999-12-30 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
DE69929440T2
(de)
|
1998-07-09 |
2006-08-17 |
Cephalon, Inc. |
Zusammensetzungen zur behandlung chronischer lymphatischer leukämie
|
JP4516690B2
(ja)
|
1998-08-11 |
2010-08-04 |
ノバルティス アーゲー |
血管形成阻害活性を有するイソキノリン誘導体
|
US6326390B1
(en)
|
1998-08-25 |
2001-12-04 |
King Pharmaceuticals Reseach And Development, Inc. |
Use of adenosine A3 receptor antagonists to inhibit tumor growth
|
ES2265929T3
(es)
|
1999-03-30 |
2007-03-01 |
Novartis Ag |
Derivados de ftalazina para el tratamiento de enfermedades inflamatorias.
|
US8791081B2
(en)
|
1999-08-13 |
2014-07-29 |
Case Western Reserve University |
MGMT inhibitor combination for the treatment of neoplastic disorders
|
US7811981B2
(en)
|
1999-08-30 |
2010-10-12 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Methods of and compositions for inhibiting the proliferation of mammalian cells
|
AR030557A1
(es)
|
2000-04-14 |
2003-08-27 |
Jagotec Ag |
Una tableta en multicapa de liberacion controlada y metodo de tratamiento
|
EP1160826A3
(en)
|
2000-05-30 |
2006-12-13 |
Ebara Corporation |
Coating, modification and etching of substrate surface with particle beam irradiation
|
US20030072794A1
(en)
|
2000-06-09 |
2003-04-17 |
Teni Boulikas |
Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes
|
US6613736B2
(en)
|
2000-06-16 |
2003-09-02 |
Thomas T. Aoki |
System and method for treating eye and nerve diseases in diabetic and non-diabetic patients
|
ATE465756T1
(de)
|
2000-06-23 |
2010-05-15 |
Mitsubishi Tanabe Pharma Corp |
Antitumoreffekt-verstärker
|
CA2422367C
(en)
|
2000-09-15 |
2010-05-18 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
US6660731B2
(en)
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
US7473691B2
(en)
|
2000-09-15 |
2009-01-06 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
US6610677B2
(en)
|
2000-09-15 |
2003-08-26 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
CN1116875C
(zh)
|
2000-10-19 |
2003-08-06 |
南京振中生物工程有限公司 |
紫杉醇脂质组合物及其制备方法
|
US6503914B1
(en)
|
2000-10-23 |
2003-01-07 |
Board Of Regents, The University Of Texas System |
Thienopyrimidine-based inhibitors of the Src family
|
EP1337244A4
(en)
|
2000-10-30 |
2006-01-11 |
Euro Celtique Sa |
HYDROCODON FORMULATIONS WITH CONTROLLED RELEASE
|
US7619005B2
(en)
|
2000-11-01 |
2009-11-17 |
Cognition Pharmaceuticals Llc |
Methods for treating cognitive impairment in humans with Multiple Sclerosis
|
US20020155565A1
(en)
|
2000-11-10 |
2002-10-24 |
Pilar Garin-Chesa |
FAP-activated anti-tumor compounds
|
KR100947185B1
(ko)
|
2000-12-21 |
2010-03-15 |
버텍스 파마슈티칼스 인코포레이티드 |
단백질 키나제 억제제로서 유용한 피라졸 화합물 및 이를 포함하는 조성물
|
US20100098691A1
(en)
|
2001-01-24 |
2010-04-22 |
S'bio Pte Ltd |
Combination of benzimidazole anti-cancer agent and a second anti-cancer agent
|
IL159048A0
(en)
|
2001-06-21 |
2004-05-12 |
Genentech Inc |
Sustained release formulation
|
US7005445B2
(en)
|
2001-10-22 |
2006-02-28 |
The Research Foundation Of State University Of New York |
Protein kinase and phosphatase inhibitors and methods for designing them
|
US20030158118A1
(en)
|
2001-11-26 |
2003-08-21 |
Weidner Morten Sloth |
Combination of cimetidine and cysteine derivatives for treating cancer
|
UA76810C2
(uk)
|
2001-12-10 |
2006-09-15 |
Мерк Енд Ко., Інк. |
Фармацевтична композиція антагоніста рецептора тахікініну у формі наночастинок
|
US7045534B2
(en)
|
2002-02-12 |
2006-05-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of reducing angiogenesis
|
AU2003219796A1
(en)
|
2002-02-20 |
2003-09-09 |
Beth Israel Deaconess Medical Center |
Conjugates comprising a biodegradable polymer and uses therefor
|
US7101576B2
(en)
|
2002-04-12 |
2006-09-05 |
Elan Pharma International Limited |
Nanoparticulate megestrol formulations
|
WO2004037814A1
(en)
|
2002-10-25 |
2004-05-06 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
TW200413381A
(en)
|
2002-11-04 |
2004-08-01 |
Hoffmann La Roche |
Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
|
US7129351B2
(en)
|
2002-11-04 |
2006-10-31 |
Hoffmann-La Roche Inc. |
Pyrimido compounds having antiproliferative activity
|
EP1560931B1
(en)
|
2002-11-14 |
2011-07-27 |
Dharmacon, Inc. |
Functional and hyperfunctional sirna
|
CL2003002287A1
(es)
|
2002-11-25 |
2005-01-14 |
Wyeth Corp |
COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS
|
US7276519B2
(en)
|
2002-11-25 |
2007-10-02 |
Wyeth |
Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors
|
JP5269281B2
(ja)
|
2002-12-30 |
2013-08-21 |
セルジーン コーポレイション |
フルオロアルコキシ置換1,3−ジヒドロイソインドリル化合物およびそれらの医薬としての使用
|
CA2517256C
(en)
|
2003-02-26 |
2013-04-30 |
Sugen, Inc. |
Aminoheteroaryl compounds as protein kinase inhibitors
|
NZ567952A
(en)
|
2003-03-24 |
2009-12-24 |
Sequoia Pharmaceuticals Inc |
Long acting biologically active conjugates
|
TW200502236A
(en)
|
2003-03-28 |
2005-01-16 |
Hoffmann La Roche |
Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
|
US7220706B1
(en)
|
2003-05-14 |
2007-05-22 |
Praxair S.T. Technology, Inc. |
Enhanced melt-textured growth
|
WO2004103958A2
(en)
|
2003-05-19 |
2004-12-02 |
Michigan State University |
Preparation of hymenialdisine derivatives and use thereof
|
US7842835B2
(en)
|
2003-07-07 |
2010-11-30 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
US20050009891A1
(en)
|
2003-07-09 |
2005-01-13 |
Lee Francis Y. |
Combination of SRC Kinase inhibitors and chemotherapeutic agents for the treatment of proliferative diseases
|
JP4889489B2
(ja)
|
2003-08-06 |
2012-03-07 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
プロテインキナーゼのインヒビターとして有用なアミノトリアゾール化合物
|
MXPA06001483A
(es)
|
2003-08-07 |
2006-05-15 |
Schering Corp |
Inhibidores novedosos de la proteina farnesil transferasa como agentes antitumorales.
|
EP1673373A2
(en)
|
2003-10-02 |
2006-06-28 |
Salmedix, Inc. |
Indole derivatives
|
HUP0303313A2
(hu)
|
2003-10-09 |
2005-07-28 |
Richter Gedeon Vegyészeti Gyár Rt. |
Transzdermális gyógyszerkészítmények
|
US7169781B2
(en)
|
2003-10-17 |
2007-01-30 |
Hoffmann-La Roche Inc. |
Imidazole derivatives and their use as pharmaceutical agents
|
EP1680119A1
(en)
|
2003-11-06 |
2006-07-19 |
Wyeth |
4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)
|
US7491725B2
(en)
|
2004-02-06 |
2009-02-17 |
Bristol-Myers Squibb Company |
Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
|
JPWO2005080392A1
(ja)
|
2004-02-19 |
2007-08-02 |
武田薬品工業株式会社 |
ピラゾロキノロン誘導体およびその用途
|
KR100881050B1
(ko)
|
2004-03-15 |
2009-01-30 |
에프. 호프만-라 로슈 아게 |
신규 디클로로―페닐―피리도 [2,3-d] 피리미딘 유도체, 그들의 제조 및 약제로서의 용도
|
WO2005092326A1
(en)
|
2004-03-22 |
2005-10-06 |
The Regents Of The University Of Michigan |
Small molecule antagonists of xiap family proteins
|
JP4993374B2
(ja)
|
2004-04-05 |
2012-08-08 |
メルク エイチディーエーシー リサーチ エルエルシー |
ヒストン脱アセチル化酵素インヒビタープロドラッグ
|
TW200538149A
(en)
|
2004-05-20 |
2005-12-01 |
Telik Inc |
Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
|
TW200600091A
(en)
|
2004-05-21 |
2006-01-01 |
Telik Inc |
Sulfonylethyl phosphorodiamidates
|
KR101254815B1
(ko)
|
2004-07-20 |
2013-09-03 |
제넨테크, 인크. |
안지오포이에틴-유사 4 단백질의 저해제, 배합물, 그의용도
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
US7479561B2
(en)
|
2004-08-16 |
2009-01-20 |
Wyeth |
4-(2,4-dichloro-5-methoxyphenyl)amino-6-methoxy-7-{[5-substituted-amino)methyl]-3-furyl}-3-quinolinecarbonitriles as kinase inhibitors
|
JP2008509964A
(ja)
|
2004-08-31 |
2008-04-03 |
エフ.ホフマン−ラ ロシュ アーゲー |
7−アミノ−3−フェニル−ジヒドロピリミド[4,5−d]ピリミジノンのアミド誘導体、これらの製造、及びプロテインキナーゼ阻害剤としての使用
|
WO2006031806A2
(en)
|
2004-09-10 |
2006-03-23 |
Atherogenics, Inc. |
2-thiopyrimidinones as therapeutic agents
|
CN101014600A
(zh)
|
2004-09-21 |
2007-08-08 |
霍夫曼-拉罗奇有限公司 |
用作蛋白激酶抑制剂的6-(2-烷基-苯基)-吡啶并[2,3-d]嘧啶类
|
US7355677B2
(en)
|
2004-12-09 |
2008-04-08 |
Asml Netherlands B.V. |
System and method for an improved illumination system in a lithographic apparatus
|
AR054416A1
(es)
|
2004-12-22 |
2007-06-27 |
Incyte Corp |
Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas.
|
CN101087787A
(zh)
|
2004-12-23 |
2007-12-12 |
霍夫曼-拉罗奇有限公司 |
苯甲酰胺衍生物,它们的制备及作为药剂的应用
|
CN101830899A
(zh)
|
2004-12-23 |
2010-09-15 |
霍夫曼-拉罗奇有限公司 |
杂环氨基甲酸酯衍生物,它们的制备及作为药剂的应用
|
US7968574B2
(en)
|
2004-12-28 |
2011-06-28 |
Kinex Pharmaceuticals, Llc |
Biaryl compositions and methods for modulating a kinase cascade
|
MX2007009888A
(es)
|
2005-02-17 |
2007-10-16 |
Synta Pharmaceuticals Corp |
Compuestos para el tratamiento de trastornos proliferativos.
|
US20060229277A1
(en)
|
2005-04-08 |
2006-10-12 |
Orbus Pharma, Inc. |
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
|
WO2006123185A2
(en)
|
2005-05-19 |
2006-11-23 |
Merck Sharp & Dohme Limited |
Sulphamides for treatment of cancer
|
CN103735560A
(zh)
|
2005-06-07 |
2014-04-23 |
耶鲁大学 |
使用克来夫定和替比夫定治疗癌症和其它病症或疾病状态的方法
|
EP1915340B1
(en)
|
2005-06-15 |
2013-08-07 |
Cardiome Pharma Corp. |
Synthetic processes for the preparation of aminocyclohexyl ether compounds
|
ATE524445T1
(de)
|
2005-06-23 |
2011-09-15 |
Merck Sharp & Dohme |
Benzocycloheptapyridine als inhibitoren der tyrosinkinase met
|
HUE035853T2
(en)
|
2005-07-18 |
2018-05-28 |
Seattle Genetics Inc |
Beta-glucuronide-linker-drug conjugates
|
WO2007014707A1
(en)
|
2005-08-01 |
2007-02-08 |
F. Hoffmann-La Roche Ag |
Heterocyclic benzylamino derivatives, their manufacture and use as pharmaceutical agents
|
ES2349476T3
(es)
|
2005-09-09 |
2011-01-03 |
Schering Corporation |
Nuevos derivados de 4-ciano, 4-amino y 4-aminometilo de compuestos de pirazolo[1,5-a]piridinas, pirazolo[1,5-c]pirimidinas y 2h-indazol y derivados de 5-ciano, 5-amino y 5-aminometilo de compuestos de imidazo[1,2-a]piridinas e imidazo[1,5-a]pirazinas, como inhibidores de cinasa dependiente de ciclina.
|
RS20080167A
(en)
|
2005-10-21 |
2009-07-15 |
Panacea Biotec Limited, |
Novel improved compositions for cancer therapy
|
WO2007053452A1
(en)
|
2005-11-01 |
2007-05-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
WO2007056221A2
(en)
|
2005-11-03 |
2007-05-18 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as kinase inhibitors
|
US8148393B2
(en)
|
2005-11-18 |
2012-04-03 |
Synthon Bv |
Zolpidem tablets
|
HUE030235T2
(en)
|
2005-12-13 |
2017-04-28 |
Incyte Holdings Corp |
Heteroaryl-substituted pyrrolo [2,3-b] pyridines and pyrrolo [2,3-b] pyrimidines as Janus kinase inhibitors
|
US8014957B2
(en)
*
|
2005-12-15 |
2011-09-06 |
Fred Hutchinson Cancer Research Center |
Genes associated with progression and response in chronic myeloid leukemia and uses thereof
|
WO2007081751A2
(en)
|
2006-01-05 |
2007-07-19 |
The Johns Hopkins University |
Compositions and methods for the treatment of cancer
|
ATE439361T1
(de)
|
2006-01-31 |
2009-08-15 |
Hoffmann La Roche |
7h-pyridoä3,4-düpyrimidin-8-one, ihre herstellung und ihre verwendung als proteinkinaseinhibitoren
|
JP5220724B2
(ja)
|
2006-03-14 |
2013-06-26 |
ニューレン ファーマシューティカルズ リミテッド |
グリシル−2−メチルプロリルグルタミン酸塩の経口製剤
|
KR20080098548A
(ko)
|
2006-03-28 |
2008-11-10 |
노파르티스 아게 |
G 단백질 관련 질환의 치료를 위한 아미드 유도체 및 그의투여
|
CA2645633A1
(en)
|
2006-04-05 |
2007-11-01 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
AU2007243519A1
(en)
|
2006-04-26 |
2007-11-08 |
Merck Sharp & Dohme Corp. |
Disubstituted aniline compounds
|
US8299052B2
(en)
|
2006-05-05 |
2012-10-30 |
Shionogi Inc. |
Pharmaceutical compositions and methods for improved bacterial eradication
|
GB0609378D0
(en)
|
2006-05-11 |
2006-06-21 |
Novartis Ag |
Organic compounds
|
US7964728B2
(en)
|
2006-07-06 |
2011-06-21 |
Solvay Pharmaceuticals B.V. |
Azaindole derivatives with a combination of partial nicotinic acetyl-choline receptor agonism and dopamine reuptake inhibition
|
TW200813021A
(en)
|
2006-07-10 |
2008-03-16 |
Merck & Co Inc |
Tyrosine kinase inhibitors
|
KR20090021313A
(ko)
|
2006-07-17 |
2009-03-02 |
노파르티스 아게 |
면역조절제로서 사용하기 위한 담즙산 아미드의 술포닐아미노카르보닐 유도체
|
US8080252B2
(en)
|
2006-07-19 |
2011-12-20 |
The Cleveland Clinic Foundation |
Compounds and methods of modulating angiogenesis
|
CN101516904A
(zh)
|
2006-07-24 |
2009-08-26 |
泰特拉洛吉克药业公司 |
二聚的iap拮抗剂
|
EP2057164A1
(en)
|
2006-08-07 |
2009-05-13 |
Incyte Corporation |
Triazolotriazines as kinase inhibitors
|
US7842293B2
(en)
|
2006-08-07 |
2010-11-30 |
Facet Biotech Corporation |
Compositions and methods using anti-CS1 antibodies to treat multiple myeloma
|
CA2659425C
(en)
|
2006-08-17 |
2017-06-20 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
CA2659991A1
(en)
|
2006-08-23 |
2008-02-28 |
Novartis Ag |
Amides as sphingomyeline inhibitors
|
US8222288B2
(en)
|
2006-08-30 |
2012-07-17 |
The Regents Of The University Of Michigan |
Small molecule inhibitors of MDM2 and the uses thereof
|
CA2974246C
(en)
|
2006-09-01 |
2020-02-25 |
Senhwa Biosciences, Inc. |
Tricyclic heteroaryl compounds and their use as protein modulators
|
US8084471B2
(en)
|
2006-09-05 |
2011-12-27 |
Yale University |
Proteomimetic compounds as inhibitors of the interaction of nuclear receptor with coactivator peptides
|
JP2010502730A
(ja)
|
2006-09-05 |
2010-01-28 |
バイパー サイエンシズ,インコーポレイティド |
癌の治療法
|
US8242080B2
(en)
|
2006-10-13 |
2012-08-14 |
The Regents Of The University Of California |
Inhibitors of the EGFR kinase targeting the asymmetric activating dimer interface
|
CN103463621B
(zh)
|
2006-10-31 |
2016-01-06 |
托莱多大学 |
Src和Src家族激酶的Na+/K+-ATP酶特异性肽抑制剂/激活剂
|
JP5103604B2
(ja)
|
2006-10-31 |
2012-12-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
プロテインキナーゼ阻害剤としての2−アミノチアゾール−4−カルボン酸アミド
|
EP2086979B1
(en)
|
2006-11-06 |
2015-06-03 |
Tolero Pharmaceuticals, Inc. |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
US20120164075A1
(en)
|
2006-11-21 |
2012-06-28 |
Jina Pharmaceuticals, Inc. |
Endoxifen methods and compositions in the treatment of mammalian diseases
|
US20080125397A1
(en)
|
2006-11-28 |
2008-05-29 |
Telik, Inc. |
2 (SULFONYL)ETHYL N,N,N',N' tetrakis(2 chloroethyl)phosphorodia
|
US7655799B2
(en)
|
2006-11-29 |
2010-02-02 |
Telik, Inc. |
2{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidates
|
JP2010512413A
(ja)
|
2006-12-11 |
2010-04-22 |
ケムファーム・インコーポレーテッド |
アンフェタミンの非標準アミノ酸結合体およびそれらの製造方法および使用方法
|
EP1932820A1
(en)
|
2006-12-14 |
2008-06-18 |
Bp Oil International Limited |
Process for manufacturing neohexene
|
WO2008079973A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Egfr binding peptides and uses thereof
|
WO2008079982A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Liposome composition for targeting egfr receptor
|
US7956216B2
(en)
*
|
2006-12-21 |
2011-06-07 |
The Walter And Eliza Hall Institute Of Medical Research |
Alpha-helical mimetics
|
US20080293648A1
(en)
|
2007-01-05 |
2008-11-27 |
Saha Pharmaceuticals, Inc. |
Compositions and Methods for Cancer Treatment
|
JP2010517976A
(ja)
|
2007-02-06 |
2010-05-27 |
ノバルティス アーゲー |
Ccr9活性の阻害剤としての1−ベンゼンスルホニル−1h−インドール誘導体
|
AU2008216327A1
(en)
|
2007-02-15 |
2008-08-21 |
Novartis Ag |
Combination of LBH589 with other therapeutic agents for treating cancer
|
BRPI0808653A2
(pt)
|
2007-03-09 |
2014-08-19 |
Univ Michigan |
Composições e métodos referindo-se a novos compostos e alvos dos mesmos.
|
US8501233B2
(en)
|
2007-03-13 |
2013-08-06 |
Wake Forest University |
Compositions and methods for treating cancer
|
PL2139484T3
(pl)
|
2007-04-10 |
2013-12-31 |
Exelixis Inc |
Sposoby leczenia raka z zastosowaniem pirydopirymidynonów jako inhibitorów PI3K alfa
|
WO2008125627A1
(en)
|
2007-04-13 |
2008-10-23 |
Novartis Ag |
Pyridazine-, pyridine- and pyrane-derivatives as gpbar1 agonisis
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
US7838495B2
(en)
|
2007-04-27 |
2010-11-23 |
University Of Maryland, Baltimore |
Compositions and methods of use of EPB1, and ErbB3 binding protein
|
MX2009011810A
(es)
|
2007-05-02 |
2010-01-14 |
Vertex Pharma |
Tiazoles y pirazoles utiles como inhibidores de cinasa.
|
WO2008144506A1
(en)
|
2007-05-16 |
2008-11-27 |
University Of Maryland, Baltimore |
Apoptotic pathway targeting for the diagnosis and treatment of cancer
|
WO2008153900A1
(en)
|
2007-06-06 |
2008-12-18 |
University Of Florida Research Foundation |
Kinase inhibitor compounds
|
US20110288023A1
(en)
|
2007-06-08 |
2011-11-24 |
The Regents Of The University Of California Office Of Technology Transfer |
Cancer drug delivery using modified transferrin
|
US8273890B2
(en)
|
2007-06-29 |
2012-09-25 |
4Sc Ag |
Thiophene-imidazopyridines
|
JP2010532756A
(ja)
|
2007-07-06 |
2010-10-14 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
mTORC1及びmTORC2の両方の阻害剤を含む組み合わせ抗癌療法
|
CN102006886A
(zh)
|
2007-08-03 |
2011-04-06 |
菲赛特生物技术公司 |
抗-tweak受体抗体的治疗用途
|
HUE027443T2
(en)
|
2007-09-10 |
2016-10-28 |
Boston Biomedical Inc |
A novel class of Stat3 pathway inhibitors and tumor stem cell inhibitors
|
US20100311678A1
(en)
|
2007-10-04 |
2010-12-09 |
Bean Bruce P |
Methods and compositions for treating cancer and modulating signal transduction and metabolism pathways
|
JP5727786B2
(ja)
|
2007-10-19 |
2015-06-03 |
シアトル ジェネティクス,インコーポレーテッド |
Cd19結合性物質およびその使用
|
CA2703125C
(en)
|
2007-10-25 |
2012-08-28 |
David J. Guerin |
Pyrazinyl-substituted pyrrolo[2,3-b]pyridines, compositions thereof, and their use in the treatment of cancer
|
CA2703600C
(en)
|
2007-11-15 |
2017-04-25 |
Ym Biosciences Australia Pty Ltd |
Fused thieno or pyrrolo pyrimidine heterocyclic compounds and use thereof as jak1, jak2, and/or jak3 inhibitors
|
CN101855221B
(zh)
|
2007-11-15 |
2013-10-30 |
P.安杰莱蒂分子生物学研究所 |
作为parp抑制剂的哒嗪酮衍生物
|
NZ585139A
(en)
|
2007-11-16 |
2012-05-25 |
Incyte Corp |
4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as jak inhibitors
|
CN101444490A
(zh)
*
|
2007-11-26 |
2009-06-03 |
天津市金圭谷木糖醇有限公司 |
一种含脱水卫矛醇经注射给药的制剂及其制备方法
|
CN101450100A
(zh)
*
|
2007-11-28 |
2009-06-10 |
天津金世制药有限公司 |
一种治疗急慢性粒细胞白血病的药物组合物
|
WO2009076629A2
(en)
|
2007-12-12 |
2009-06-18 |
The Regents Of The University Of Michigan |
Compositions and methods for treating cancer
|
PL2240172T3
(pl)
|
2007-12-21 |
2014-08-29 |
Novartis Ag |
Kombinacja nilotynibu i chlorambucylu do leczenia przewlekłej białaczki limfocytowej
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
US20090275519A1
(en)
*
|
2008-02-08 |
2009-11-05 |
Aileron Therapeutics, Inc. |
Therapeutic peptidomimetic macrocycles
|
WO2009102707A2
(en)
|
2008-02-11 |
2009-08-20 |
Auspex Pharmaceuticals, Inc. |
Substituted oxazaphosphorines
|
US20090209340A1
(en)
|
2008-02-14 |
2009-08-20 |
Aruze Gaming America, Inc. |
Gaming Apparatus Capable of Conversation with Player and Control Method Thereof
|
WO2009109927A2
(en)
|
2008-03-05 |
2009-09-11 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Glp-1 receptor agonists and related active pharmaceutical ingredients for treatment of cancer
|
ES2602577T3
(es)
|
2008-03-11 |
2017-02-21 |
Incyte Holdings Corporation |
Derivados de azetidina y ciclobutano como inhibidores de JAK
|
EP2110377A1
(en)
|
2008-04-15 |
2009-10-21 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
KR20210100223A
(ko)
|
2008-04-30 |
2021-08-13 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
WO2009143018A2
(en)
|
2008-05-19 |
2009-11-26 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
CA2726317A1
(en)
|
2008-06-03 |
2009-12-10 |
Merck Sharp & Dohme Corp. |
Inhibitors of akt activity
|
GB2475183B
(en)
|
2008-06-04 |
2011-11-23 |
Gw Pharma Ltd |
Cannabinoids in combination with non-cannabinoid chemotherapeutic agent that are selective estrogen receptor modulators
|
EP2133334A1
(en)
|
2008-06-09 |
2009-12-16 |
DAC S.r.l. |
Heterocyclic derivatives as HDAC inhibitors
|
EP2915532B1
(en)
*
|
2008-06-17 |
2016-10-19 |
Wyeth LLC |
Antineoplastic combinations containing hki-272 and vinorelbine
|
US8207195B2
(en)
|
2008-06-26 |
2012-06-26 |
Inspire Pharmaceuticals, Inc. |
Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds
|
KR101927291B1
(ko)
|
2008-07-08 |
2018-12-10 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸
|
WO2010009334A1
(en)
|
2008-07-17 |
2010-01-21 |
Colorado State University Research Foundation |
Method for preparing largazole analogs and uses thereof
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
US20120230991A1
(en)
|
2008-07-29 |
2012-09-13 |
Douglas Kim Graham |
Methods and compounds for enhancing anti-cancer therapy
|
WO2010021822A2
(en)
|
2008-07-30 |
2010-02-25 |
The Regents Of The University Of California |
Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites
|
US8242106B2
(en)
|
2008-08-01 |
2012-08-14 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
NZ591113A
(en)
|
2008-08-26 |
2012-07-27 |
Boehringer Ingelheim Int |
Thienopyrimidine linked to phenyl or pyridine via an nh amine for pharmaceutical compositions
|
US20100068302A1
(en)
|
2008-09-17 |
2010-03-18 |
Traslational Cancer Drugs Pharma, S.L. |
Methods and compositions for the treatment of cancer
|
US8476282B2
(en)
|
2008-11-03 |
2013-07-02 |
Intellikine Llc |
Benzoxazole kinase inhibitors and methods of use
|
US20100111901A1
(en)
|
2008-11-03 |
2010-05-06 |
Auspex Pharmaceuticals, Inc. |
Triazole inhibitors of aromatase
|
KR101805754B1
(ko)
|
2008-12-08 |
2017-12-07 |
먼디파머 인터내셔널 코포레이션 리미티드 |
단백질 수용체 티로신 키나아제 억제제의 조성물
|
US20100150896A1
(en)
|
2008-12-12 |
2010-06-17 |
Auspex Pharmaceuticals, Inc. |
Diaminoquinazoline inhibitors of dihydrofolate reductase
|
PA8851101A1
(es)
|
2008-12-16 |
2010-07-27 |
Lilly Co Eli |
Compuesto amino pirazol
|
US20110318430A1
(en)
|
2008-12-18 |
2011-12-29 |
New York University |
Tumor therapy with antitumor agents in combination with sindbis virus-based vectors
|
US20100173013A1
(en)
|
2009-01-08 |
2010-07-08 |
Denis Drygin |
Treatment of neoplastic disorders using combination therapies
|
MX2011008221A
(es)
*
|
2009-02-04 |
2011-08-17 |
Bipar Sciences Inc |
Tratamiento de cancer de pulmon con un compuesto de nitrobenzamida en combinacion con un inhibidor de un factor de crecimieno.
|
EP3620154A1
(en)
|
2009-02-06 |
2020-03-11 |
University Of Southern California |
Therapeutic compositions comprising monoterpenes
|
US8901301B2
(en)
|
2009-03-11 |
2014-12-02 |
Plexxikon Inc. |
Pyrrolo[2,3-]pyridine kinase inhibitors
|
WO2010117668A1
(en)
|
2009-03-30 |
2010-10-14 |
Cerulean Pharma Inc. |
Polymer-agent conjugates, particles, compositions, and related methods of use
|
US8574829B2
(en)
|
2009-03-31 |
2013-11-05 |
The Trustees Of The University Of Pennsylvania |
Methods of treating cancer with phenformin
|
US8680139B2
(en)
|
2009-04-01 |
2014-03-25 |
Progenra |
Anti-neoplastic compounds, compositions and methods
|
CA2758071C
(en)
|
2009-04-06 |
2018-01-09 |
Agios Pharmaceuticals, Inc. |
Pyruvate kinase m2 modulators, therapeutic compositions and related methods of use
|
US20100291025A1
(en)
|
2009-04-13 |
2010-11-18 |
Auspex Pharmaceuticals, Inc. |
Indazole inhibitors of tyrosine kinase
|
US20110053968A1
(en)
|
2009-06-09 |
2011-03-03 |
Auspex Pharmaceuticals, Inc. |
Aminopyrimidine inhibitors of tyrosine kinase
|
US9151762B2
(en)
|
2009-06-12 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Identification of DSG-3 as a biomarker for the detection of metastasis in lymph nodes
|
US8232318B2
(en)
|
2009-07-31 |
2012-07-31 |
The General Hospital Corporation |
Approaches to treat cancer using HB-EGF inhibitors
|
PT2470546E
(pt)
|
2009-08-28 |
2013-10-14 |
Takeda Pharmaceutical |
Compostos de hexa-hidrooxazinopteridina para serem utilizados como inibidores de mtor
|
US20110071115A1
(en)
|
2009-09-11 |
2011-03-24 |
Cylene Pharmaceuticals, Inc. |
Pharmaceutically useful heterocycle-substituted lactams
|
KR20120104180A
(ko)
|
2009-09-16 |
2012-09-20 |
사일린 파마슈티칼스, 인크 |
신규한 트리시클릭 단백질 키나제 조절제
|
NZ597833A
(en)
|
2009-09-28 |
2014-01-31 |
Hoffmann La Roche |
Benzoxazepin pi3k inhibitor compounds and methods of use
|
US8304577B2
(en)
|
2009-10-09 |
2012-11-06 |
Bristol-Myers Squibb Company |
Modulators of G protein-coupled receptor 88
|
JP5099731B1
(ja)
*
|
2009-10-14 |
2012-12-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
p53活性を増大する置換ピペリジン及びその使用
|
EA201792376A3
(ru)
|
2009-10-23 |
2018-08-31 |
Милленниум Фармасьютикалз, Инк. |
Молекулы анти-gcc антитела и соответствующие композиции и способы
|
AU2010326268B2
(en)
|
2009-12-04 |
2016-11-03 |
Senhwa Biosciences, Inc. |
Pyrazolopyrimidines and related heterocycles as CK2 inhibitors
|
US8445517B2
(en)
|
2009-12-11 |
2013-05-21 |
Dana-Farber Cancer Institute |
Stat modulators
|
US20110195066A1
(en)
|
2010-02-05 |
2011-08-11 |
Auspex Pharmaceuticals, Inc. |
Quinoline inhibitors of tyrosine kinase
|
US20110206661A1
(en)
|
2010-02-24 |
2011-08-25 |
Auspex Pharmaceuticals, Inc. |
Trimethoxyphenyl inhibitors of tyrosine kinase
|
UY33241A
(es)
|
2010-02-26 |
2011-09-30 |
Boehringer Ingelheim Int |
?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
|
CA2791114A1
(en)
|
2010-02-26 |
2011-09-01 |
Boehringer Ingelheim International Gmbh |
Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions
|
WO2011109799A1
(en)
|
2010-03-05 |
2011-09-09 |
Karyopharm Therapeutics, Inc. |
Nuclear transport modulatiors and uses thereof
|
US8389525B2
(en)
|
2010-05-05 |
2013-03-05 |
Renee Desai |
Small molecules for inhibition of protein kinases
|
CA2798760A1
(en)
|
2010-05-12 |
2011-11-17 |
Vertex Pharmaceuticals Incorporated |
2-aminopyridine derivatives useful as inhibitors of atr kinase
|
CN103025353A
(zh)
*
|
2010-05-14 |
2013-04-03 |
霍夫曼-拉罗奇有限公司 |
治疗方法
|
CA2807292C
(en)
*
|
2010-08-02 |
2019-10-22 |
University Of Central Florida Research Foundation, Inc. |
Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of stat proteins
|
JP2013537552A
(ja)
*
|
2010-08-18 |
2013-10-03 |
デル マー ファーマスーティカルズ |
ジアンヒドロガラクチトール及びジアセチルジアンヒドロガラクチトール等の置換ヘキシトールを含む準最適に投与された化合物の治療的有効性を改良するための組成物及び方法
|
US9029103B2
(en)
*
|
2010-08-27 |
2015-05-12 |
Illumina Cambridge Limited |
Methods for sequencing polynucleotides
|
WO2012044832A1
(en)
|
2010-09-30 |
2012-04-05 |
Fetzer Oliver S |
Methods of treating a subject and related particles, polymers and compositions
|
EP2637669A4
(en)
|
2010-11-10 |
2014-04-02 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds and their use
|
SG182016A1
(en)
*
|
2010-12-14 |
2012-07-30 |
Univ Singapore |
Method of detecting resistance to cancer therapy
|
EP2827869A4
(en)
*
|
2012-03-23 |
2015-09-23 |
Dennis Brown |
COMPOSITIONS AND METHODS FOR IMPROVING THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ITS ANALOGUES INCLUDING MESOINDIGO
|
WO2013169600A1
(en)
*
|
2012-05-09 |
2013-11-14 |
Delmar Pharmaceuticals |
Veterinary use of dianhydrogalactitol, diacetyldianhydrogalactitol, and dibromodulcitol to treat malignancies
|
US8729286B2
(en)
*
|
2012-05-10 |
2014-05-20 |
Massachusetts Institute Of Technology |
Platinum compounds as treatment for cancers, and related methods, kits, and compositions
|