JP2015517310A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015517310A5 JP2015517310A5 JP2015511775A JP2015511775A JP2015517310A5 JP 2015517310 A5 JP2015517310 A5 JP 2015517310A5 JP 2015511775 A JP2015511775 A JP 2015511775A JP 2015511775 A JP2015511775 A JP 2015511775A JP 2015517310 A5 JP2015517310 A5 JP 2015517310A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- host cell
- seq
- amino acid
- position corresponding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 17
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 10
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 10
- 150000001413 amino acids Chemical group 0.000 claims 9
- 229940024606 amino acid Drugs 0.000 claims 8
- 230000000813 microbial effect Effects 0.000 claims 8
- QPRQEDXDYOZYLA-UHFFFAOYSA-N 2-methylbutan-1-ol Chemical compound CCC(C)CO QPRQEDXDYOZYLA-UHFFFAOYSA-N 0.000 claims 6
- 238000006467 substitution reaction Methods 0.000 claims 6
- WTLNOANVTIKPEE-UHFFFAOYSA-N 2-acetyloxypropanoic acid Chemical compound OC(=O)C(C)OC(C)=O WTLNOANVTIKPEE-UHFFFAOYSA-N 0.000 claims 4
- AMIMRNSIRUDHCM-UHFFFAOYSA-N Isopropylaldehyde Chemical compound CC(C)C=O AMIMRNSIRUDHCM-UHFFFAOYSA-N 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- CTMXBOCTJPQVDZ-UHFFFAOYSA-N 2,2-dihydroxy-3-methylbutanoic acid Chemical compound CC(C)C(O)(O)C(O)=O CTMXBOCTJPQVDZ-UHFFFAOYSA-N 0.000 claims 2
- QHKABHOOEWYVLI-UHFFFAOYSA-N 3-methyl-2-oxobutanoic acid Chemical compound CC(C)C(=O)C(O)=O QHKABHOOEWYVLI-UHFFFAOYSA-N 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 102220313176 rs749459367 Human genes 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims 1
- JTEYKUFKXGDTEU-UHFFFAOYSA-N 2,3-dihydroxy-3-methylbutanoic acid Chemical compound CC(C)(O)C(O)C(O)=O JTEYKUFKXGDTEU-UHFFFAOYSA-N 0.000 claims 1
- KSAIICDEQGEQBK-UHFFFAOYSA-N 3-hydroxy-2,2-dimethylbutanedioic acid Chemical compound OC(=O)C(C)(C)C(O)C(O)=O KSAIICDEQGEQBK-UHFFFAOYSA-N 0.000 claims 1
- 239000005695 Ammonium acetate Substances 0.000 claims 1
- 102220522807 Brain acid soluble protein 1_S86A_mutation Human genes 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 239000004215 Carbon black (E152) Substances 0.000 claims 1
- 101150096607 Fosl2 gene Proteins 0.000 claims 1
- 102220630801 Interferon alpha-8_A68E_mutation Human genes 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 102220480756 Nucleotide pyrophosphatase_I13L_mutation Human genes 0.000 claims 1
- 102000004316 Oxidoreductases Human genes 0.000 claims 1
- 108090000854 Oxidoreductases Proteins 0.000 claims 1
- 102220469877 Protein argonaute-3_F50A_mutation Human genes 0.000 claims 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 230000006696 biosynthetic metabolic pathway Effects 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 102200163308 c.158T>C Human genes 0.000 claims 1
- 102200108209 c.205G>A Human genes 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 239000000446 fuel Substances 0.000 claims 1
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 229960003136 leucine Drugs 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 229940014662 pantothenate Drugs 0.000 claims 1
- 235000019161 pantothenic acid Nutrition 0.000 claims 1
- 239000011713 pantothenic acid Substances 0.000 claims 1
- 102200071829 rs34620296 Human genes 0.000 claims 1
- 102200140931 rs794727301 Human genes 0.000 claims 1
- 102220099823 rs878853788 Human genes 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
- 229960004295 valine Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645832P | 2012-05-11 | 2012-05-11 | |
| US61/645,832 | 2012-05-11 | ||
| US201361787480P | 2013-03-15 | 2013-03-15 | |
| US61/787,480 | 2013-03-15 | ||
| PCT/US2013/040627 WO2013176909A2 (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015517310A JP2015517310A (ja) | 2015-06-22 |
| JP2015517310A5 true JP2015517310A5 (enExample) | 2016-06-23 |
| JP6321631B2 JP6321631B2 (ja) | 2018-05-09 |
Family
ID=48877508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511775A Active JP6321631B2 (ja) | 2012-05-11 | 2013-05-10 | ケトール酸レダクトイソメラーゼ酵素及び使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9169467B2 (enExample) |
| EP (1) | EP2847326A2 (enExample) |
| JP (1) | JP6321631B2 (enExample) |
| KR (1) | KR20150014953A (enExample) |
| CN (1) | CN104619835B (enExample) |
| AU (1) | AU2013266727A1 (enExample) |
| BR (1) | BR112014028153A2 (enExample) |
| CA (1) | CA2873109A1 (enExample) |
| MX (2) | MX2014013446A (enExample) |
| NZ (1) | NZ701099A (enExample) |
| WO (1) | WO2013176909A2 (enExample) |
| ZA (1) | ZA201407713B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| KR101573775B1 (ko) | 2007-04-18 | 2015-12-04 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 고도 활성 케톨-산 리덕토아이소머라아제 효소를 이용한 아이소부탄올의 발효 생산 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| KR20110063576A (ko) | 2008-09-29 | 2011-06-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 효모에서 증가된 이종성 Ｆｅ-Ｓ 효소 활성 |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| US9297016B2 (en) | 2010-02-17 | 2016-03-29 | Butamax Advanced Biofuels Llc | Activity of Fe—S cluster requiring proteins |
| EP3269806B1 (en) | 2010-09-07 | 2020-05-27 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| CA2831130C (en) | 2011-03-24 | 2021-10-26 | Butamax (Tm) Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| JP6093764B2 (ja) | 2011-07-28 | 2017-03-08 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法 |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CN104284981A (zh) | 2012-03-23 | 2015-01-14 | 布特马斯先进生物燃料有限责任公司 | 在针对产丁醇生物的培养基中补充乙酸盐 |
| WO2013176909A2 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| US9512408B2 (en) | 2012-09-26 | 2016-12-06 | Butamax Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| WO2014160050A1 (en) | 2013-03-14 | 2014-10-02 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| CA2957920A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
| CN110177801B (zh) | 2016-11-09 | 2024-02-23 | 丹尼斯科美国公司 | 具有改善的醇生产的酵母 |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| KR101960501B1 (ko) * | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Ｎａｄｈ 친화적인 신규 케톨산 리덕토아이소머라제 |
| US11308274B2 (en) | 2019-05-17 | 2022-04-19 | International Business Machines Corporation | Word grouping using a plurality of models |
| CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
| WO2024197704A1 (zh) * | 2023-03-30 | 2024-10-03 | 安徽华恒生物科技股份有限公司 | 一种产泛解酸的重组微生物及其应用 |
| CN117417949B (zh) * | 2023-10-19 | 2024-12-20 | 云南农业大学 | 雪胆细胞色素氧化酶HcCYP81Q58转基因酵母工程菌及其应用 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
| FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
| CA2380616C (en) | 1999-08-18 | 2011-05-24 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high titer |
| EP1268774A2 (en) | 2000-03-21 | 2003-01-02 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
| US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
| MXPA03011813A (es) | 2001-07-02 | 2004-07-01 | Kaneka Corp | Metodo para la modificacion de enzimas y variantes de oxido reductasa. |
| MXPA05009553A (es) | 2003-03-10 | 2006-03-17 | Broin And Associates Inc | Metodo para producir etanol utilizando almidon como materia prima. |
| SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
| JP5149785B2 (ja) | 2005-04-12 | 2013-02-20 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | エタノールを得るためのバイオマスの処理 |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8273558B2 (en) * | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| NZ566406A (en) | 2005-10-26 | 2012-04-27 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| CA2678261A1 (en) | 2007-02-09 | 2008-08-14 | The Regents Of The University Of California | Biofuel production by recombinant microorganisms |
| KR101573775B1 (ko) | 2007-04-18 | 2015-12-04 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 고도 활성 케톨-산 리덕토아이소머라아제 효소를 이용한 아이소부탄올의 발효 생산 |
| EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| EP2215243A2 (en) | 2007-10-31 | 2010-08-11 | GEVO, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
| ATE495260T1 (de) | 2007-12-17 | 2011-01-15 | Suntory Holdings Ltd | Mutantes ilv5-gen und verwendung davon |
| EP2677028B1 (en) | 2007-12-20 | 2016-03-09 | Butamax (TM) Advanced Biofuels LLC | Ketol-acid reductoisomerase using NADH |
| US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| JP2011507532A (ja) | 2007-12-23 | 2011-03-10 | ジーヴォ，インコーポレイテッド | 高収率でイソブタノールを産生する酵母生物 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| US8906666B2 (en) | 2008-05-22 | 2014-12-09 | Butamax Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| KR20110063576A (ko) | 2008-09-29 | 2011-06-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 효모에서 증가된 이종성 Ｆｅ-Ｓ 효소 활성 |
| CA2735948A1 (en) | 2008-09-29 | 2011-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| MX2011003238A (es) | 2008-09-29 | 2011-04-28 | Butamax Tm Advanced Biofuels | Identificacion y uso de dihidroxiacido deshidratasas [2fe-2s] bacterianas. |
| WO2010037105A1 (en) | 2008-09-29 | 2010-04-01 | Butamax™ Advanced Biofuels LLC | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| BRPI0913680A2 (pt) | 2008-09-29 | 2019-09-24 | Butamax Advanced Biofuels Llc | "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol" |
| BRPI0914521A2 (pt) | 2008-10-27 | 2016-07-26 | Butamax Advanced Biofuels Llc | célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol |
| US20100143997A1 (en) | 2008-10-31 | 2010-06-10 | Thomas Buelter | Engineered microorganisms capable of producing target compounds under anaerobic conditions |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
| US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| US8232089B2 (en) | 2009-08-12 | 2012-07-31 | Gevo, Inc. | Cytosolic isobutanol pathway localization for the production of isobutanol |
| US20110244536A1 (en) | 2009-09-29 | 2011-10-06 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
| WO2011041426A1 (en) | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
| IN2012DN02396A (enExample) | 2009-09-29 | 2015-08-21 | Butamax Tm Advanced Biofuels | |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| BR112012012492A2 (pt) | 2009-11-24 | 2019-09-24 | Gevo Inc | métodos para aumentar atividade de diidróxi ácido desidratase para aperfeiçoar produção de combustíveis, produtos químicos e aminoácidos |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| KR20120099509A (ko) | 2009-12-29 | 2012-09-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 재조합 숙주 세포에서 육탄당 키나아제의 발현 |
| RU2012138943A (ru) | 2010-02-12 | 2014-03-20 | Джево, Инк. | Дрожжевые микроорганизмы с пониженным накоплением побочных продуктов для улучшенного производства топлив, химикатов и аминокислот |
| US9297016B2 (en) | 2010-02-17 | 2016-03-29 | Butamax Advanced Biofuels Llc | Activity of Fe—S cluster requiring proteins |
| BR112012031847A2 (pt) * | 2010-06-17 | 2016-02-16 | Butamax Tm Advanced Biofuels | cultura de produção para a produção fermentativa de butanol, método de produção de butanol, método para a produção de butanol, método para aumentar a tolerância de uma cultura de produção para a produção fermentativa de butanol e cultura de produção para produção fermentativa de butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| EP3269806B1 (en) * | 2010-09-07 | 2020-05-27 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| CA2831130C (en) | 2011-03-24 | 2021-10-26 | Butamax (Tm) Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
| CA2838519A1 (en) | 2011-06-17 | 2012-12-20 | Butamax Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
| JP6093764B2 (ja) | 2011-07-28 | 2017-03-08 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトイソ吉草酸デカルボキシラーゼ酵素およびその使用方法 |
| AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CN104284981A (zh) | 2012-03-23 | 2015-01-14 | 布特马斯先进生物燃料有限责任公司 | 在针对产丁醇生物的培养基中补充乙酸盐 |
| WO2013176909A2 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| US9512408B2 (en) | 2012-09-26 | 2016-12-06 | Butamax Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
| WO2014160050A1 (en) | 2013-03-14 | 2014-10-02 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
-
2013
- 2013-05-10 WO PCT/US2013/040627 patent/WO2013176909A2/en not_active Ceased
- 2013-05-10 CA CA2873109A patent/CA2873109A1/en not_active Abandoned
- 2013-05-10 MX MX2014013446A patent/MX2014013446A/es unknown
- 2013-05-10 CN CN201380036539.6A patent/CN104619835B/zh not_active Expired - Fee Related
- 2013-05-10 MX MX2018004620A patent/MX370134B/es unknown
- 2013-05-10 BR BR112014028153-0A patent/BR112014028153A2/pt not_active Application Discontinuation
- 2013-05-10 AU AU2013266727A patent/AU2013266727A1/en not_active Abandoned
- 2013-05-10 EP EP13742293.7A patent/EP2847326A2/en not_active Withdrawn
- 2013-05-10 US US13/891,963 patent/US9169467B2/en active Active
- 2013-05-10 KR KR1020147034485A patent/KR20150014953A/ko not_active Withdrawn
- 2013-05-10 NZ NZ701099A patent/NZ701099A/en not_active IP Right Cessation
- 2013-05-10 JP JP2015511775A patent/JP6321631B2/ja active Active
-
2014
- 2014-10-23 ZA ZA2014/07713A patent/ZA201407713B/en unknown
-
2015
- 2015-09-14 US US14/853,108 patent/US9388392B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015517310A5 (enExample) | ||
| Atsumi et al. | Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli | |
| Moon et al. | One hundred years of clostridial butanol fermentation | |
| EP2054502B1 (en) | Novel engineered microorganism producing homo-succinic acid and method for preparing succinic acid using the same | |
| Kato et al. | Complete genome sequence of Lactococcus lactis IO-1, a lactic acid bacterium that utilizes xylose and produces high levels of L-lactic acid | |
| Romano et al. | Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a | |
| JP2016521577A5 (enExample) | ||
| JP2017511156A5 (enExample) | ||
| AR083354A1 (es) | Polipeptidos variantes cbh i (celobiohidrolasas i) con reducida inhibicion de producto | |
| Dubey et al. | Methylotrophy in mycobacteria: dissection of the methanol metabolism pathway in Mycobacterium smegmatis | |
| NZ728287A (en) | Method for producing acetoin | |
| Zhang et al. | Cloning, expression and characterization of glycerol dehydrogenase involved in 2, 3-butanediol formation in Serratia marcescens H30 | |
| Yang et al. | Cell regeneration and cyclic catalysis of engineered Kluyveromyces marxianus of a D-psicose-3-epimerase gene from Agrobacterium tumefaciens for D-allulose production | |
| BR112016017092B1 (pt) | Método para produzir um produto selecionado do grupo consistindo de etanol, 2,3-butanodiol e ácido acético | |
| Tan et al. | Characterization of two novel butanol dehydrogenases involved in butanol degradation in syngas‐utilizing bacterium Clostridium ljungdahlii DSM 13528 | |
| AR075810A1 (es) | Lipasa optimizadas por par de codones (cpo) y derivados de la misma | |
| CN103930391B (zh) | 通过经改良的重组菌株来生产异丙醇 | |
| CN103740771A (zh) | 克雷伯氏肺炎杆菌生产2r,3r-丁二醇的方法 | |
| CN104774817A (zh) | 一种果糖基转移酶及其编码基因与应用 | |
| CN106755044B (zh) | 高效产氢功能基因载体pET32a-fdhF及其构建和应用 | |
| JP2018537111A5 (enExample) | ||
| CN105400711A (zh) | 一株产l-苹果酸的酿酒酵母工程菌的构建及应用 | |
| CN102660515A (zh) | 一种酶活性及热稳定性提高的谷氨酰胺转氨酶 | |
| NZ604088A (en) | Cloning and expression of the genes encoding key clostridial catalyzing mechanisms for syngas to ethanol production and functional characterization thereof | |
| Bolot et al. | Genome sequences of three atypical Xanthomonas campestris pv. campestris strains, CN14, CN15, and CN16 |