JP2013545461A5 - - Google Patents
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- JP2013545461A5 JP2013545461A5 JP2013538190A JP2013538190A JP2013545461A5 JP 2013545461 A5 JP2013545461 A5 JP 2013545461A5 JP 2013538190 A JP2013538190 A JP 2013538190A JP 2013538190 A JP2013538190 A JP 2013538190A JP 2013545461 A5 JP2013545461 A5 JP 2013545461A5
- Authority
- JP
- Japan
- Prior art keywords
- genbank
- locus
- atcc824
- replaced
- clostridium acetobutylicum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 claims 22
- 125000003729 nucleotide group Chemical group 0.000 claims 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 16
- 241000193401 Clostridium acetobutylicum Species 0.000 claims 15
- 235000011187 glycerol Nutrition 0.000 claims 8
- 241001112695 Clostridiales Species 0.000 claims 7
- 230000002103 transcriptional effect Effects 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims 5
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims 5
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims 5
- 239000001963 growth medium Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 108010078791 Carrier Proteins Proteins 0.000 claims 3
- 108090000069 P-type ATPases Proteins 0.000 claims 3
- 102000003697 P-type ATPases Human genes 0.000 claims 3
- 150000001768 cations Chemical class 0.000 claims 3
- 230000004060 metabolic process Effects 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000018697 Membrane Proteins Human genes 0.000 claims 2
- 108010052285 Membrane Proteins Proteins 0.000 claims 2
- 101710201576 Putative membrane protein Proteins 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 230000035897 transcription Effects 0.000 claims 2
- 238000013518 transcription Methods 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 101100116134 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) dcd gene Proteins 0.000 claims 1
- 101100398771 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ldh1 gene Proteins 0.000 claims 1
- 102100031687 Galactose mutarotase Human genes 0.000 claims 1
- 102100036284 Hepcidin Human genes 0.000 claims 1
- 108010072039 Histidine kinase Proteins 0.000 claims 1
- 101001021253 Homo sapiens Hepcidin Proteins 0.000 claims 1
- 101710124567 L-cystine-binding protein TcyJ Proteins 0.000 claims 1
- 102000003855 L-lactate dehydrogenase Human genes 0.000 claims 1
- 108700023483 L-lactate dehydrogenases Proteins 0.000 claims 1
- 102100031551 Methionine synthase Human genes 0.000 claims 1
- 101710163328 Methionine synthase Proteins 0.000 claims 1
- 108091022872 aldose 1-epimerase Proteins 0.000 claims 1
- 230000037354 amino acid metabolism Effects 0.000 claims 1
- 239000003225 biodiesel Substances 0.000 claims 1
- 239000006227 byproduct Substances 0.000 claims 1
- 230000023852 carbohydrate metabolic process Effects 0.000 claims 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 230000009087 cell motility Effects 0.000 claims 1
- 108700040031 dCTP deaminases Proteins 0.000 claims 1
- 150000002009 diols Chemical class 0.000 claims 1
- 230000037149 energy metabolism Effects 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 125000001477 organic nitrogen group Chemical group 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41216210P | 2010-11-10 | 2010-11-10 | |
| EP10306234 | 2010-11-10 | ||
| US61/412,162 | 2010-11-10 | ||
| EP10306234.5 | 2010-11-10 | ||
| PCT/EP2011/069789 WO2012062832A1 (en) | 2010-11-10 | 2011-11-10 | Microorganisms for 1,3-propanediol production using high glycerine concentration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013545461A JP2013545461A (ja) | 2013-12-26 |
| JP2013545461A5 true JP2013545461A5 (enExample) | 2016-05-12 |
Family
ID=43828229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538190A Pending JP2013545461A (ja) | 2010-11-10 | 2011-11-10 | 高グリセリン濃度を用いる１，３−プロパンジオール生産用微生物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130177956A1 (enExample) |
| EP (2) | EP2638172A1 (enExample) |
| JP (1) | JP2013545461A (enExample) |
| KR (1) | KR20140005170A (enExample) |
| CN (1) | CN103298945A (enExample) |
| AR (1) | AR083799A1 (enExample) |
| BR (1) | BR112013011417A2 (enExample) |
| CA (1) | CA2814441A1 (enExample) |
| TW (1) | TWI542685B (enExample) |
| WO (1) | WO2012062832A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9328360B2 (en) | 2013-09-06 | 2016-05-03 | The Curators Of The University Of Missouri | Conversion of glycerol to 1,3-propanediol under haloalkaline conditions |
| CA3028871A1 (en) | 2016-07-08 | 2018-01-11 | Metabolic Explorer | Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (pts) |
| CN106190901B (zh) | 2016-07-15 | 2020-06-26 | 上海交通大学 | 一种菌及其获取方法和应用 |
| CN106978380A (zh) * | 2016-12-14 | 2017-07-25 | 天津科技大学 | 一株高木糖耐性肺炎克雷伯氏菌株及其构建方法 |
| DK3583221T3 (da) * | 2017-02-20 | 2021-09-06 | Metabolic Explorer Sa | Mikrobielt konsortium omfattende clostridia til fremstilling af 1,3-propandiol ud fra glycerol |
| EP3438270A1 (en) * | 2017-08-04 | 2019-02-06 | Metabolic Explorer | Microorganism and method for improved 1,3-propanediol production by fermentation on a culture medium with high glycerine content |
| US11293039B2 (en) | 2017-10-02 | 2022-04-05 | Metabolic Explorer | Method for producing organic acid salts from fermentation broth |
| BR112021002573A2 (pt) * | 2018-08-10 | 2021-05-11 | Metabolic Explorer | microrganismos com produção de 1,3-propanediol e ácido butírico melhorada |
| CN112358986B (zh) * | 2020-11-09 | 2022-10-21 | 华南理工大学 | 一种丁酸梭菌及其在固定化发酵生产1，3-丙二醇的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2796081B1 (fr) | 1999-07-09 | 2003-09-26 | Agronomique Inst Nat Rech | Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs |
| CN1327001C (zh) | 2005-06-03 | 2007-07-18 | 清华大学 | 利用生物柴油副产物甘油生产1,3－丙二醇的方法 |
| WO2008005295A2 (en) * | 2006-06-29 | 2008-01-10 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| JP5203375B2 (ja) | 2006-10-03 | 2013-06-05 | メタボリック エクスプローラー | クロストリジウム菌における染色体取り込みおよびｄｎａ配列置換法 |
| KR20090090319A (ko) | 2006-10-31 | 2009-08-25 | 메타볼릭 익스플로러 | 높은 수율로 글리세롤로부터 1,3-프로판디올을 생물학적으로 생산하는 방법 |
| WO2009068110A1 (en) | 2007-11-30 | 2009-06-04 | Metabolic Explorer | Method for purifying an alcohol from a fermentation broth |
| MY152034A (en) | 2008-10-03 | 2014-08-15 | Metabolic Explorer Sa | Method for purifying an alcohol from a fermentation broth using a falling film, a wiped film, a thin film or a short path evaporator |
| EP2248904A1 (en) * | 2009-05-05 | 2010-11-10 | Metabolic Explorer | Continuous culture for 1,3-propanediol production using high glycerine concentration |
-
2011
- 2011-11-08 AR ARP110104169A patent/AR083799A1/es unknown
- 2011-11-09 TW TW100140808A patent/TWI542685B/zh active
- 2011-11-10 BR BR112013011417A patent/BR112013011417A2/pt not_active Application Discontinuation
- 2011-11-10 JP JP2013538190A patent/JP2013545461A/ja active Pending
- 2011-11-10 US US13/823,709 patent/US20130177956A1/en not_active Abandoned
- 2011-11-10 KR KR1020137014637A patent/KR20140005170A/ko not_active Withdrawn
- 2011-11-10 CN CN2011800646210A patent/CN103298945A/zh active Pending
- 2011-11-10 WO PCT/EP2011/069789 patent/WO2012062832A1/en not_active Ceased
- 2011-11-10 CA CA2814441A patent/CA2814441A1/en not_active Abandoned
- 2011-11-10 EP EP11779682.1A patent/EP2638172A1/en not_active Ceased
- 2011-11-10 EP EP15199896.0A patent/EP3012325A1/en not_active Withdrawn
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