JP2013545461A - 高グリセリン濃度を用いる1,3−プロパンジオール生産用微生物 - Google Patents
高グリセリン濃度を用いる1,3−プロパンジオール生産用微生物 Download PDFInfo
- Publication number
- JP2013545461A JP2013545461A JP2013538190A JP2013538190A JP2013545461A JP 2013545461 A JP2013545461 A JP 2013545461A JP 2013538190 A JP2013538190 A JP 2013538190A JP 2013538190 A JP2013538190 A JP 2013538190A JP 2013545461 A JP2013545461 A JP 2013545461A
- Authority
- JP
- Japan
- Prior art keywords
- glycerin
- population
- strain
- locus
- propanediol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/145—Clostridium
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41216210P | 2010-11-10 | 2010-11-10 | |
| EP10306234 | 2010-11-10 | ||
| US61/412,162 | 2010-11-10 | ||
| EP10306234.5 | 2010-11-10 | ||
| PCT/EP2011/069789 WO2012062832A1 (en) | 2010-11-10 | 2011-11-10 | Microorganisms for 1,3-propanediol production using high glycerine concentration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013545461A true JP2013545461A (ja) | 2013-12-26 |
| JP2013545461A5 JP2013545461A5 (enExample) | 2016-05-12 |
Family
ID=43828229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538190A Pending JP2013545461A (ja) | 2010-11-10 | 2011-11-10 | 高グリセリン濃度を用いる1,3−プロパンジオール生産用微生物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130177956A1 (enExample) |
| EP (2) | EP2638172A1 (enExample) |
| JP (1) | JP2013545461A (enExample) |
| KR (1) | KR20140005170A (enExample) |
| CN (1) | CN103298945A (enExample) |
| AR (1) | AR083799A1 (enExample) |
| BR (1) | BR112013011417A2 (enExample) |
| CA (1) | CA2814441A1 (enExample) |
| TW (1) | TWI542685B (enExample) |
| WO (1) | WO2012062832A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020529849A (ja) * | 2017-08-04 | 2020-10-15 | メタボリック エクスプローラー | グリセリン高含有培養培地上での発酵による1,3−プロパンジオールの改良された生産を行うための微生物および方法 |
| JP2021533764A (ja) * | 2018-08-10 | 2021-12-09 | メタボリック エクスプローラー | 1,3−プロパンジオールおよび酪酸の生産が改善された微生物 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9328360B2 (en) | 2013-09-06 | 2016-05-03 | The Curators Of The University Of Missouri | Conversion of glycerol to 1,3-propanediol under haloalkaline conditions |
| CA3028871A1 (en) | 2016-07-08 | 2018-01-11 | Metabolic Explorer | Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (pts) |
| CN106190901B (zh) | 2016-07-15 | 2020-06-26 | 上海交通大学 | 一种菌及其获取方法和应用 |
| CN106978380A (zh) * | 2016-12-14 | 2017-07-25 | 天津科技大学 | 一株高木糖耐性肺炎克雷伯氏菌株及其构建方法 |
| DK3583221T3 (da) * | 2017-02-20 | 2021-09-06 | Metabolic Explorer Sa | Mikrobielt konsortium omfattende clostridia til fremstilling af 1,3-propandiol ud fra glycerol |
| US11293039B2 (en) | 2017-10-02 | 2022-04-05 | Metabolic Explorer | Method for producing organic acid salts from fermentation broth |
| CN112358986B (zh) * | 2020-11-09 | 2022-10-21 | 华南理工大学 | 一种丁酸梭菌及其在固定化发酵生产1,3-丙二醇的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2796081B1 (fr) | 1999-07-09 | 2003-09-26 | Agronomique Inst Nat Rech | Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs |
| CN1327001C (zh) | 2005-06-03 | 2007-07-18 | 清华大学 | 利用生物柴油副产物甘油生产1,3-丙二醇的方法 |
| WO2008005295A2 (en) * | 2006-06-29 | 2008-01-10 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| JP5203375B2 (ja) | 2006-10-03 | 2013-06-05 | メタボリック エクスプローラー | クロストリジウム菌における染色体取り込みおよびdna配列置換法 |
| KR20090090319A (ko) | 2006-10-31 | 2009-08-25 | 메타볼릭 익스플로러 | 높은 수율로 글리세롤로부터 1,3-프로판디올을 생물학적으로 생산하는 방법 |
| WO2009068110A1 (en) | 2007-11-30 | 2009-06-04 | Metabolic Explorer | Method for purifying an alcohol from a fermentation broth |
| MY152034A (en) | 2008-10-03 | 2014-08-15 | Metabolic Explorer Sa | Method for purifying an alcohol from a fermentation broth using a falling film, a wiped film, a thin film or a short path evaporator |
| EP2248904A1 (en) * | 2009-05-05 | 2010-11-10 | Metabolic Explorer | Continuous culture for 1,3-propanediol production using high glycerine concentration |
-
2011
- 2011-11-08 AR ARP110104169A patent/AR083799A1/es unknown
- 2011-11-09 TW TW100140808A patent/TWI542685B/zh active
- 2011-11-10 BR BR112013011417A patent/BR112013011417A2/pt not_active Application Discontinuation
- 2011-11-10 JP JP2013538190A patent/JP2013545461A/ja active Pending
- 2011-11-10 US US13/823,709 patent/US20130177956A1/en not_active Abandoned
- 2011-11-10 KR KR1020137014637A patent/KR20140005170A/ko not_active Withdrawn
- 2011-11-10 CN CN2011800646210A patent/CN103298945A/zh active Pending
- 2011-11-10 WO PCT/EP2011/069789 patent/WO2012062832A1/en not_active Ceased
- 2011-11-10 CA CA2814441A patent/CA2814441A1/en not_active Abandoned
- 2011-11-10 EP EP11779682.1A patent/EP2638172A1/en not_active Ceased
- 2011-11-10 EP EP15199896.0A patent/EP3012325A1/en not_active Withdrawn
Non-Patent Citations (3)
| Title |
|---|
| JPN6015046535; GONZALEZ-PAJUELO, M., et al.: Metabolic Engineering 7, 2005, pp.329-336 * |
| JPN6015046537; GONZALEZ-PAJUELO, M., et al.: APPLIED AND ENVIRONMENTAL MICROBIOLOGY 72(1), 2006, pp.96-101 * |
| JPN6015046539; CELINSKA, E.: Biotechnology Advances 28, 20100331, pp.519-530 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020529849A (ja) * | 2017-08-04 | 2020-10-15 | メタボリック エクスプローラー | グリセリン高含有培養培地上での発酵による1,3−プロパンジオールの改良された生産を行うための微生物および方法 |
| JP7175961B2 (ja) | 2017-08-04 | 2022-11-21 | メタボリック エクスプローラー | グリセリン高含有培養培地上での発酵による1,3-プロパンジオールの改良された生産を行うための微生物および方法 |
| JP2021533764A (ja) * | 2018-08-10 | 2021-12-09 | メタボリック エクスプローラー | 1,3−プロパンジオールおよび酪酸の生産が改善された微生物 |
| JP7569783B2 (ja) | 2018-08-10 | 2024-10-18 | メタボリック エクスプローラー | 1,3-プロパンジオールおよび酪酸の生産が改善された微生物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3012325A1 (en) | 2016-04-27 |
| WO2012062832A1 (en) | 2012-05-18 |
| CA2814441A1 (en) | 2012-05-18 |
| TW201226563A (en) | 2012-07-01 |
| US20130177956A1 (en) | 2013-07-11 |
| TWI542685B (zh) | 2016-07-21 |
| AR083799A1 (es) | 2013-03-20 |
| BR112013011417A2 (pt) | 2017-04-04 |
| KR20140005170A (ko) | 2014-01-14 |
| EP2638172A1 (en) | 2013-09-18 |
| CN103298945A (zh) | 2013-09-11 |
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