JP2016521577A5 - - Google Patents

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JP2016521577A5
JP2016521577A5 JP2016519714A JP2016519714A JP2016521577A5 JP 2016521577 A5 JP2016521577 A5 JP 2016521577A5 JP 2016519714 A JP2016519714 A JP 2016519714A JP 2016519714 A JP2016519714 A JP 2016519714A JP 2016521577 A5 JP2016521577 A5 JP 2016521577A5
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fatty acid
recombinant microorganism
seq
microorganism according
mutations
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JP2016519714A
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JP7004500B2 (ja
JP2016521577A (ja
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Priority claimed from PCT/US2014/042594 external-priority patent/WO2014201474A1/en
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JP2016519714A 2013-06-14 2014-06-16 ω－ヒドロキシル化脂肪酸誘導体を生産する方法 Expired - Fee Related JP7004500B2 (ja)

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JP2021129428A JP7406529B2 (ja) 2013-06-14 2021-08-06 ω－ヒドロキシル化脂肪酸誘導体を生産する方法

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US201361835464P 2013-06-14 2013-06-14
US61/835,464 2013-06-14
PCT/US2014/042594 WO2014201474A1 (en) 2013-06-14 2014-06-16 Methods of producing omega-hydroxylated fatty acid derivatives

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JP2019183765A Division JP7168539B2 (ja) 2013-06-14 2019-10-04 ω－ヒドロキシル化脂肪酸誘導体を生産する方法
JP2021129428A Division JP7406529B2 (ja) 2013-06-14 2021-08-06 ω－ヒドロキシル化脂肪酸誘導体を生産する方法

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JP2016521577A JP2016521577A (ja) 2016-07-25
JP2016521577A5 true JP2016521577A5 (enExample) 2021-09-24
JP7004500B2 JP7004500B2 (ja) 2022-02-04

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JP2016519714A Expired - Fee Related JP7004500B2 (ja) 2013-06-14 2014-06-16 ω－ヒドロキシル化脂肪酸誘導体を生産する方法
JP2019183765A Expired - Fee Related JP7168539B2 (ja) 2013-06-14 2019-10-04 ω－ヒドロキシル化脂肪酸誘導体を生産する方法
JP2021129428A Active JP7406529B2 (ja) 2013-06-14 2021-08-06 ω－ヒドロキシル化脂肪酸誘導体を生産する方法

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JP2021129428A Active JP7406529B2 (ja) 2013-06-14 2021-08-06 ω－ヒドロキシル化脂肪酸誘導体を生産する方法

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US (3) US10711288B2 (enExample)
EP (2) EP2984490B1 (enExample)
JP (3) JP7004500B2 (enExample)
KR (4) KR102387905B1 (enExample)
CN (3) CN118374462A (enExample)
AU (2) AU2014277874B2 (enExample)
BR (2) BR122020002919B1 (enExample)
CA (1) CA2915229A1 (enExample)
MX (2) MX374736B (enExample)
MY (3) MY203897A (enExample)
SI (1) SI2984490T1 (enExample)
WO (1) WO2014201474A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014277874B2 (en) 2013-06-14 2020-12-03 Genomatica, Inc. Methods of producing omega-hydroxylated fatty acid derivatives
CA2944558A1 (en) 2014-04-10 2015-10-15 REG Life Sciences, LLC Semisynthetic routes to organic compounds
WO2015176020A1 (en) 2014-05-16 2015-11-19 Provivi, Inc. Synthesis of olefinic alcohols via enzymatic terminal hydroxylation
MX372803B (es) * 2014-06-16 2020-07-03 Genomatica Inc Polipeptidos de fusion relacionados con omega-hidroxilasa con propiedades mejoradas.
CN111748511A (zh) 2014-07-18 2020-10-09 基因组股份公司 微生物的脂肪二醇产生
US11319562B2 (en) 2015-04-15 2022-05-03 Ramon Gonzalez Modified fatty acid biosynthesis with ACP-dependent thiolases
WO2016168247A1 (en) * 2015-04-15 2016-10-20 William Marsh Rice University Modified fatty acid biosynthesis with acp-dependent thiolases
US11091741B2 (en) 2015-10-27 2021-08-17 Korea Research Institute Of Bioscience And Biotechnology Method for producing medium chain diol
KR101903553B1 (ko) * 2015-10-27 2018-10-04 한국생명공학연구원 중쇄 아미노카르복시산의 생산 방법
WO2017101987A1 (en) 2015-12-15 2017-06-22 REG Life Sciences, LLC Omega-hydroxylase-related fusion polypeptide variants with improved properties
CN107201356A (zh) * 2016-03-17 2017-09-26 中国科学院青岛生物能源与过程研究所 支撑p450脂肪酸脱羧酶活性的还原伴侣蛋白组合及其应用
BR112019020784A2 (pt) 2017-04-03 2020-04-28 Genomatica, Inc. variantes de tioesterase com atividade melhorada para a produção de derivados de ácidos graxos de cadeia média
KR102170282B1 (ko) * 2017-12-15 2020-10-29 건국대학교 산학협력단 α,ω-디올류 생산하는 재조합 미생물 및 α,ω-디올류의 생산방법
TWI701040B (zh) * 2018-03-19 2020-08-11 國立臺灣大學 蛋白質的用途及包含該蛋白質之全細胞催化系統及其應用
CN111989399B (zh) 2018-04-16 2024-07-12 韩国生命工学研究院 多不饱和脂肪酸的多羟基衍生物的制备方法
EP3824071A4 (en) * 2018-07-17 2022-04-20 Conagen Inc. BIOSYNTHETIC MANUFACTURE OF GAMMA LACTONES
KR102117828B1 (ko) 2018-07-19 2020-06-02 서울대학교산학협력단 레귤론 변이를 통한 지방산 및 지방산 유도체 생산에서 불포화도 감소
WO2020047304A1 (en) 2018-08-31 2020-03-05 Genomatica, Inc. Xylr mutant for improved xylose utilization or improved co-utilization of glucose and xylose
CN111218485B (zh) * 2018-11-26 2023-01-24 中国科学院大连化学物理研究所 一种生产ω-1-羟基脂肪酸的方法
CN111218430B (zh) * 2018-11-26 2022-06-14 中国科学院大连化学物理研究所 一种nadh类似物依赖型的细胞色素p450还原酶及其应用
US20210392935A1 (en) * 2018-11-30 2021-12-23 Evonik Operations Gmbh Preparation comprising a probiotic strain of the genus bacillus megaterium and a polyunsaturated fatty acid component
CN111592996A (zh) * 2019-12-09 2020-08-28 福建省水产研究所（福建水产病害防治中心） 一种芽孢杆菌cqn-2高密度发酵培养方法
US20220025380A1 (en) * 2020-07-22 2022-01-27 The Regents Of The University Of California Host cells and methods for producing hydroxylated methyl ketone compounds
US12649937B2 (en) 2021-03-29 2026-06-09 Genomatica, Inc. Production of non-native monounsaturated fatty acids in bacteria
JP2023005283A (ja) * 2021-06-28 2023-01-18 出光興産株式会社 ペプチドタグ付加タンパク質を用いた代謝物生産
US20250207159A1 (en) 2022-03-16 2025-06-26 Genomatica, Inc. Microorganisms And Methods For Production Of Fatty Acid Derivatives With Reduced Levels Of Byproducts
CN114480513A (zh) * 2022-04-01 2022-05-13 北京林业大学 一种基因编辑酵母体外合成麝香酮的方法
CN115537369B (zh) * 2022-11-09 2024-03-01 云南农业大学 2-十二烯二酸促进蒙氏假单胞菌生长和定殖的应用
CN116064362B (zh) * 2022-12-15 2025-10-28 浙江大学 一种利用葡萄糖从头合成12-氨基月桂酸的基因工程菌及其构建和应用
CN116622544B (zh) * 2023-02-21 2026-07-28 广东海洋大学 鼻甲海神单胞菌及其应用
CN116790529B (zh) * 2023-05-24 2025-01-17 天津大学 P450 bm3蛋白突变体及其应用
CN117343970B (zh) * 2023-10-24 2025-01-21 杭州佳嘉乐生物技术有限公司 一种提升植物油脂亲肤感的油脂发酵方法
CN120699859B (zh) * 2024-11-13 2026-06-12 中国科学院深圳先进技术研究院 重组菌及其构建方法和应用
CN120254135B (zh) * 2025-06-04 2025-08-29 中国农业科学院北京畜牧兽医研究所 一种高精度、抗干扰的内毒素分析方法及试剂盒
CN120519413A (zh) * 2025-06-04 2025-08-22 齐鲁工业大学(山东省科学院) 一种提高底物耐受性及催化效率的细胞色素p450酶突变体及其应用
CN122012636A (zh) * 2026-04-14 2026-05-12 天津凯莱英生物科技有限公司 生物合成ω-羟基脂肪酸的方法和基因工程菌

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1305083C (en) 1987-02-18 1992-07-14 Yoshiharu Kimura Microorganism belonging to genus rhodococcus, and a process for producing alkene derivative and unsaturated fatty acid
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US5028539A (en) 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
US5482846A (en) 1988-08-31 1996-01-09 University Of Florida Ethanol production in Gram-positive microbes
US5424202A (en) 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
EP0528881A4 (en) 1990-04-24 1993-05-26 Stratagene Methods for phenotype creation from multiple gene populations
US5602030A (en) 1994-03-28 1997-02-11 University Of Florida Research Foundation Recombinant glucose uptake system
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US5939250A (en) 1995-12-07 1999-08-17 Diversa Corporation Production of enzymes having desired activities by mutagenesis
WO1999018224A1 (en) 1997-10-06 1999-04-15 The Centre National De Recherche Scientifique Plant fatty acid hydroxylase genes
CN100379716C (zh) 2002-04-29 2008-04-09 陶氏环球技术公司 关于种子油工业应用的综合化学方法
US20040242831A1 (en) 2003-05-30 2004-12-02 Dong Tian Enzyme catalyzed polyesters and polyol polymers
EP1811029A4 (en) * 2004-11-10 2008-03-12 Marine Biotech Inst Co Ltd PROCESS FOR ISOLATING THE P450 GENE
JP2009079057A (ja) 2005-04-22 2009-04-16 Mitsubishi Chemicals Corp ポリエステル及びその製造方法
AU2007254151A1 (en) 2006-05-19 2007-11-29 Ls9, Inc. Production of fatty acids and derivatives thereof
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
CN101558027B (zh) 2006-10-13 2013-10-16 埃莱文斯可更新科学公司 通过复分解反应制备α，ω-二羧酸烯烃衍生物的方法
US8501973B2 (en) 2006-10-13 2013-08-06 Elevance Renewable Sciences, Inc. Synthesis of terminal alkenes from internal alkenes via olefin metathesis
US8110093B2 (en) 2007-03-14 2012-02-07 Ls9, Inc. Process for producing low molecular weight hydrocarbons from renewable resources
CA3035878C (en) 2007-03-28 2023-01-03 REG Life Sciences, LLC Enhanced production of fatty acid derivatives
US20080293060A1 (en) 2007-04-23 2008-11-27 Ls9, Inc. Methods and Compositions for Identification of Hydrocarbon Response, Transport and Biosynthesis Genes
JP5912251B2 (ja) 2007-05-22 2016-06-01 アールイージー ライフ サイエンシズ リミテッド ライアビリティ カンパニー 炭化水素産生遺伝子およびその使用方法
JP5324129B2 (ja) 2007-05-25 2013-10-23 神戸天然物化学株式会社 Ｃｙｐ１５３による芳香族化合物の製造方法
WO2009009391A2 (en) 2007-07-06 2009-01-15 Ls9, Inc. Systems and methods for the production of fatty esters
FR2921362B1 (fr) 2007-09-20 2012-09-21 Arkema France Procede de synthese d'acides gras omega-insatures
WO2009042950A1 (en) 2007-09-27 2009-04-02 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
TWI351779B (en) 2007-12-03 2011-11-01 Advance Smart Ind Ltd Apparatus and method for correcting residual capac
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
JP2011522525A (ja) 2008-05-16 2011-08-04 エルエス９・インコーポレイテッド 炭化水素を製造するための方法および組成物
WO2009142983A1 (en) 2008-05-23 2009-11-26 Alliant Techsystems Inc. Broadband patch antenna and antenna system
US8273694B2 (en) 2008-07-28 2012-09-25 Jeffrey A Brown Synthetic compositions obtained from algae
WO2010021711A1 (en) 2008-08-18 2010-02-25 Ls9, Inc. Systems and methods for the production of mixed fatty esters
TW201016657A (en) 2008-08-28 2010-05-01 Mitsui Chemicals Inc Olefin production process
CA3038491A1 (en) 2008-10-07 2010-04-15 REG Life Sciences, LLC Bacterial host cells engineered to express a carboxylic acid reductase and a thioesterase
WO2010062480A2 (en) 2008-10-28 2010-06-03 Ls9, Inc. Methods and compositions for producing fatty alcohols
US7989875B2 (en) 2008-11-24 2011-08-02 Nxp B.V. BiCMOS integration of multiple-times-programmable non-volatile memories
EP3564345A1 (en) 2008-12-23 2019-11-06 REG Life Sciences, LLC Methods and compositions related to thioesterase enzymes
US8071799B2 (en) 2009-01-29 2011-12-06 Energy & Environmental Research Center Foundation Chain-selective synthesis of fuel components and chemical feedstocks
JP5353768B2 (ja) 2009-03-06 2013-11-27 国立大学法人東京工業大学 樹脂組成物
CA2758298A1 (en) 2009-04-10 2010-10-14 Ls9, Inc. Production of commercial biodiesel from genetically modified microorganisms
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos
EP2424989A2 (en) 2009-05-01 2012-03-07 The Regents of The University of California Product of fatty acid esters from biomass polymers
CN102656273B (zh) 2009-09-25 2016-05-25 Reg生命科学有限责任公司 脂肪酸衍生物的产生
US8237003B2 (en) 2009-11-09 2012-08-07 Exxonmobil Chemical Patents Inc. Metathesis catalyst and process for use thereof
US8809563B2 (en) 2009-11-09 2014-08-19 Exxonmobil Chemical Patents Inc. Metathesis catalyst and process for use thereof
US8361769B1 (en) * 2009-11-16 2013-01-29 U.S. Department Of Energy Regioselective alkane hydroxylation with a mutant CYP153A6 enzyme
US20110124071A1 (en) 2009-11-17 2011-05-26 LS9, Inc Methods and compositions for producing hydrocarbons
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
WO2011127409A2 (en) * 2010-04-08 2011-10-13 Ls9, Inc. Methods and compositions related to fatty alcohol biosynthetic enzymes
SG185780A1 (en) 2010-05-28 2013-01-30 Solazyme Inc Tailored oils produced from recombinant heterotrophic microorganisms
US8372610B2 (en) 2010-09-15 2013-02-12 Ls9, Inc. Production of odd chain fatty acid derivatives in recombinant microbial cells
JP2012097163A (ja) 2010-10-29 2012-05-24 Dainippon Printing Co Ltd ポリエステル樹脂組成物
WO2012071439A1 (en) * 2010-11-22 2012-05-31 The Regents Of The University Of California Host cells and methods for producing diacid compounds
CA2825691C (en) 2011-02-02 2020-08-25 Solazyme, Inc. Tailored oils produced from recombinant oleaginous microorganisms
CA2841796C (en) * 2011-07-06 2021-06-29 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
DE102011110946A1 (de) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen
EP2639308A1 (de) 2012-03-12 2013-09-18 Evonik Industries AG Enzymatische omega-Oxidation und -Aminierung von Fettsäuren
KR20150069015A (ko) * 2012-10-15 2015-06-22 게노마티카 인코포레이티드 특정 길이의 지방 알콜 및 관련 화합물의 생산을 위한 미생물 및 방법
FR3003577B1 (fr) 2013-03-19 2016-05-06 Ferropem Inoculant a particules de surface
AU2014277874B2 (en) 2013-06-14 2020-12-03 Genomatica, Inc. Methods of producing omega-hydroxylated fatty acid derivatives
MX372803B (es) 2014-06-16 2020-07-03 Genomatica Inc Polipeptidos de fusion relacionados con omega-hidroxilasa con propiedades mejoradas.
WO2017101987A1 (en) 2015-12-15 2017-06-22 REG Life Sciences, LLC Omega-hydroxylase-related fusion polypeptide variants with improved properties

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