JP2015513524A5 - - Google Patents
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- JP2015513524A5 JP2015513524A5 JP2014556075A JP2014556075A JP2015513524A5 JP 2015513524 A5 JP2015513524 A5 JP 2015513524A5 JP 2014556075 A JP2014556075 A JP 2014556075A JP 2014556075 A JP2014556075 A JP 2014556075A JP 2015513524 A5 JP2015513524 A5 JP 2015513524A5
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- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261596931P | 2012-02-09 | 2012-02-09 | |
| US61/596,931 | 2012-02-09 | ||
| PCT/EP2013/052557 WO2013117705A1 (en) | 2012-02-09 | 2013-02-08 | Targeting of chondroitin sulfate glycans |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017232702A Division JP2018076333A (ja) | 2012-02-09 | 2017-12-04 | コンドロイチン硫酸グリカンのターゲティング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015513524A JP2015513524A (ja) | 2015-05-14 |
| JP2015513524A5 true JP2015513524A5 (https=) | 2016-02-25 |
| JP6517018B2 JP6517018B2 (ja) | 2019-05-22 |
Family
ID=47714079
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014556075A Active JP6517018B2 (ja) | 2012-02-09 | 2013-02-08 | コンドロイチン硫酸グリカンのターゲティング |
| JP2017232702A Pending JP2018076333A (ja) | 2012-02-09 | 2017-12-04 | コンドロイチン硫酸グリカンのターゲティング |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017232702A Pending JP2018076333A (ja) | 2012-02-09 | 2017-12-04 | コンドロイチン硫酸グリカンのターゲティング |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11787844B2 (https=) |
| EP (1) | EP2812024B1 (https=) |
| JP (2) | JP6517018B2 (https=) |
| CN (1) | CN104136041B (https=) |
| AU (1) | AU2013217986B2 (https=) |
| BR (1) | BR112014018630A2 (https=) |
| CA (1) | CA2861051C (https=) |
| DK (1) | DK2812024T3 (https=) |
| EA (1) | EA031876B1 (https=) |
| ES (1) | ES2676029T3 (https=) |
| IL (1) | IL233594B (https=) |
| PL (1) | PL2812024T3 (https=) |
| SG (2) | SG10201606195UA (https=) |
| WO (1) | WO2013117705A1 (https=) |
| ZA (1) | ZA201405187B (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2968440T3 (pl) | 2013-03-15 | 2019-12-31 | Zymeworks Inc. | Związki cytotoksyczne i antymitotyczne oraz sposoby ich stosowania |
| AU2014364520B2 (en) * | 2013-12-20 | 2020-01-02 | The General Hospital Corporation | Methods and assays relating to circulating tumor cells |
| AU2014373640B2 (en) * | 2013-12-27 | 2018-08-30 | Var2 Pharmaceuticals Aps | VAR2CSA-drug conjugates |
| RU2729194C2 (ru) | 2013-12-27 | 2020-08-05 | Займворкс Инк. | Сульфонамидсодержащие связывающие системы для лекарственных конъюгатов |
| JP6246030B2 (ja) * | 2014-03-12 | 2017-12-13 | 東芝メディカルシステムズ株式会社 | 病理染色装置及び病理染色方法 |
| AU2015318556C1 (en) | 2014-09-17 | 2021-01-07 | Zymeworks Bc Inc. | Cytotoxic and anti-mitotic compounds, and methods of using the same |
| CA2977434A1 (en) * | 2015-02-26 | 2016-09-01 | Var2 Pharmaceuticals Aps | Immunotherapeutic targeting of placental-like chondroitin sulfate using chimeric antigen receptors (cars) and immunotherapeutic targeting of cancer using cars with split-protein binding systems |
| CN106459224B (zh) * | 2015-11-26 | 2019-12-27 | 广州中科蓝华生物科技有限公司 | 一种抗胎盘样硫酸软骨素的嵌合抗原受体及其应用 |
| CN105753991B (zh) * | 2015-11-26 | 2019-12-27 | 广州中科蓝华生物科技有限公司 | 一种抗胎盘样硫酸软骨素的嵌合抗原受体及其应用 |
| WO2017088623A1 (zh) * | 2015-11-26 | 2017-06-01 | 广州中科蓝华生物科技有限公司 | 一种抗胎盘样硫酸软骨素的嵌合抗原受体及其应用 |
| CN108700567B (zh) * | 2016-03-07 | 2022-05-10 | 爱丽卜塔有限公司 | 癌症生物标志物 |
| WO2017179015A1 (en) * | 2016-04-15 | 2017-10-19 | Glaxosmithkline Intellectual Property Development Limited | Compositions for the treatment of cancer |
| US10517958B2 (en) | 2016-10-04 | 2019-12-31 | Zymeworks Inc. | Compositions and methods for the treatment of platinum-drug resistant cancer |
| CN106512022B (zh) * | 2016-10-12 | 2019-09-27 | 广东艾时代生物科技有限责任公司 | 羟基红花黄色素a-红细胞黏附硫酸软骨素a受体蛋白多肽复合物在制备抗肿瘤药物的应用 |
| WO2018107930A1 (zh) * | 2016-12-14 | 2018-06-21 | 中国科学院上海巴斯德研究所 | 外周血循环肿瘤细胞检测体系及其应用 |
| WO2018162596A1 (en) * | 2017-03-07 | 2018-09-13 | Elypta Ab | Cancer biomarkers |
| CN109568596B (zh) * | 2017-09-28 | 2021-07-27 | 中国科学院深圳先进技术研究院 | 胎盘样硫酸软骨素a靶向运载体系及其制备方法和应用 |
| CN109568598B (zh) * | 2017-09-28 | 2021-07-27 | 中国科学院深圳先进技术研究院 | 用于药物流产的胎盘靶向纳米颗粒及其制备方法和应用 |
| WO2019061648A1 (zh) * | 2017-09-28 | 2019-04-04 | 中国科学院深圳先进技术研究院 | 靶向胎盘样硫酸软骨素a的多肽、靶向递送系统及其制备方法和应用 |
| CN109589413B (zh) * | 2017-09-28 | 2021-07-27 | 中国科学院深圳先进技术研究院 | 靶向胎盘样硫酸软骨素a的多肽、靶向纳米颗粒及其制备方法和应用 |
| CN109568597B (zh) * | 2017-09-28 | 2021-07-27 | 中国科学院深圳先进技术研究院 | 靶向胎盘样硫酸软骨素a的多肽药物偶联物及其制备方法和应用 |
| CN109589416B (zh) * | 2017-09-28 | 2021-07-27 | 中国科学院深圳先进技术研究院 | 胎盘样硫酸软骨素a靶向纳米投递系统及其制备方法和应用 |
| CN108570118B (zh) * | 2017-10-17 | 2020-07-03 | 中国科学院深圳先进技术研究院 | 一种胎盘样硫酸软骨素a或其衍生物的亲和层析纯化方法 |
| AU2017441551B2 (en) * | 2017-11-29 | 2024-05-16 | Guangzhou Lamgene Biomedical Technology Co., Ltd. | Chimeric antigen receptor and application thereof |
| CN108828224A (zh) * | 2018-04-24 | 2018-11-16 | 上海市第十人民医院 | 肝癌血清肿瘤标志物acan |
| US20210278406A1 (en) * | 2018-07-13 | 2021-09-09 | Varct Diagnostic Aps | Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa |
| WO2020033398A1 (en) * | 2018-08-06 | 2020-02-13 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating atii cell-dependent lung diseases |
| WO2020077532A1 (zh) * | 2018-10-16 | 2020-04-23 | 中国科学院深圳先进技术研究院 | 一种基于胎盘样硫酸软骨素a的癌症筛查和早期诊断的试剂方法 |
| CN109387627B (zh) * | 2018-10-16 | 2021-09-24 | 中国科学院深圳先进技术研究院 | 一种基于胎盘样硫酸软骨素a的癌症筛查和早期诊断的试剂方法 |
| KR102167443B1 (ko) * | 2019-03-25 | 2020-10-19 | 주식회사 카티프라임 | 체외 골관절염 모델 및 이를 이용한 골관절염 치료제 스크리닝 방법 |
| CN110124045A (zh) * | 2019-04-30 | 2019-08-16 | 云南大学 | 疟原虫var2csa蛋白在抗肿瘤药物中的应用 |
| EP4004017A4 (en) * | 2019-07-23 | 2023-11-22 | CSTS Health Care Inc. | PLATE-ENABLED DELIVERY OF THERAPEUTIC COMPOUNDS |
| CN112759654A (zh) * | 2019-11-06 | 2021-05-07 | 深圳普菲科生命科技有限公司 | 一种病毒囊膜蛋白装配系统及其方法和应用 |
| CN113318225B (zh) * | 2020-02-28 | 2024-01-19 | 无锡派列博生物医药科技有限公司 | 肿瘤免疫增强剂及其制法和应用 |
| CN113967268A (zh) * | 2020-07-21 | 2022-01-25 | 深圳先进技术研究院 | 一种子宫内膜异位症病灶靶向纳米投递系统及其制备方法和应用 |
| CN113956331A (zh) * | 2020-07-21 | 2022-01-21 | 深圳先进技术研究院 | 异位子宫内膜识别多肽及其衍生物和应用 |
| WO2022109168A2 (en) * | 2020-11-19 | 2022-05-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Novel var2csa immunogens and methods of use thereof |
| EP4015004A1 (en) * | 2020-12-18 | 2022-06-22 | Phi Pharma SA | Proteoglycan specific branched peptides |
| CN113740521A (zh) * | 2021-08-27 | 2021-12-03 | 安徽贝铭生物科技有限公司 | 检测尿液中癌胚硫酸软骨素的制剂在制备诊断泌尿系统恶性肿瘤的制剂、试剂盒中的应用 |
| WO2023118150A1 (en) * | 2021-12-22 | 2023-06-29 | Royal College Of Surgeons In Ireland | A conjugate for use in localising a molecule to the vascular endothelium. |
| CN114075298B (zh) * | 2022-01-07 | 2022-04-29 | 广州中科蓝华生物科技有限公司 | 一种索烃化的var2csa重组蛋白及其制备方法和应用 |
| US20250179211A1 (en) * | 2022-02-07 | 2025-06-05 | Var2 Pharmaceuticals Aps | Antibodies and antibody fragments and analogues specific for chondroitin sulfate |
| CN118459569B (zh) * | 2022-12-09 | 2025-06-06 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 一种var2csa重组蛋白及其制备方法和应用 |
| EP4733762A1 (en) | 2023-06-22 | 2026-04-29 | Toray Industries, Inc. | Capturing method and detection method for extracellular vesicles derived from cancer cells, and kit |
| WO2025259639A1 (en) * | 2024-06-11 | 2025-12-18 | Virginia Commonwealth University | Methods for treating cancers characterized by chondroitin sulfate expression using polynuclear platinum compounds |
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| US4203570A (en) | 1978-08-23 | 1980-05-20 | The Western States Machine Company | Power-operated loading gate for centrifugal machines incorporating an auxiliary drive device |
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4546082A (en) | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
| US4599311A (en) | 1982-08-13 | 1986-07-08 | Kawasaki Glenn H | Glycolytic promotersfor regulated protein expression: protease inhibitor |
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| NZ207926A (en) | 1983-04-25 | 1988-04-29 | Genentech Inc | Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast |
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| WO2013020090A2 (en) * | 2011-08-04 | 2013-02-07 | The Regents Of The University Of California | STREPTOCOCCAL GLcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM |
-
2013
- 2013-02-08 AU AU2013217986A patent/AU2013217986B2/en active Active
- 2013-02-08 WO PCT/EP2013/052557 patent/WO2013117705A1/en not_active Ceased
- 2013-02-08 US US14/376,295 patent/US11787844B2/en active Active
- 2013-02-08 ES ES13704077.0T patent/ES2676029T3/es active Active
- 2013-02-08 CN CN201380008730.XA patent/CN104136041B/zh active Active
- 2013-02-08 BR BR112014018630A patent/BR112014018630A2/pt not_active Application Discontinuation
- 2013-02-08 SG SG10201606195UA patent/SG10201606195UA/en unknown
- 2013-02-08 DK DK13704077.0T patent/DK2812024T3/en active
- 2013-02-08 CA CA2861051A patent/CA2861051C/en active Active
- 2013-02-08 SG SG11201403988WA patent/SG11201403988WA/en unknown
- 2013-02-08 JP JP2014556075A patent/JP6517018B2/ja active Active
- 2013-02-08 PL PL13704077T patent/PL2812024T3/pl unknown
- 2013-02-08 EA EA201491494A patent/EA031876B1/ru not_active IP Right Cessation
- 2013-02-08 EP EP13704077.0A patent/EP2812024B1/en active Active
-
2014
- 2014-07-10 IL IL233594A patent/IL233594B/en unknown
- 2014-07-15 ZA ZA2014/05187A patent/ZA201405187B/en unknown
-
2016
- 2016-10-05 US US15/285,956 patent/US9926350B2/en active Active
- 2016-10-05 US US15/285,830 patent/US9932375B2/en active Active
-
2017
- 2017-12-04 JP JP2017232702A patent/JP2018076333A/ja active Pending
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