AU4647889A - Insect signal peptide mediated secretion of recombinant proteins - Google Patents

Insect signal peptide mediated secretion of recombinant proteins

Info

Publication number
AU4647889A
AU4647889A AU46478/89A AU4647889A AU4647889A AU 4647889 A AU4647889 A AU 4647889A AU 46478/89 A AU46478/89 A AU 46478/89A AU 4647889 A AU4647889 A AU 4647889A AU 4647889 A AU4647889 A AU 4647889A
Authority
AU
Australia
Prior art keywords
signal peptide
recombinant proteins
peptide mediated
mediated secretion
insect signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46478/89A
Inventor
Robin Clark
Patricia E. Devlin
Edward C. O'rourke
Michael Piatak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of AU4647889A publication Critical patent/AU4647889A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
AU46478/89A 1988-11-18 1989-11-16 Insect signal peptide mediated secretion of recombinant proteins Abandoned AU4647889A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27322088A 1988-11-18 1988-11-18
US273220 1988-11-18

Publications (1)

Publication Number Publication Date
AU4647889A true AU4647889A (en) 1990-06-12

Family

ID=23043026

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46478/89A Abandoned AU4647889A (en) 1988-11-18 1989-11-16 Insect signal peptide mediated secretion of recombinant proteins

Country Status (3)

Country Link
AU (1) AU4647889A (en)
CA (1) CA2003248A1 (en)
WO (1) WO1990005783A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649177B1 (en) * 1989-06-28 1992-06-19 Pont A Mousson SEALING WITH ANNULAR ANCHOR HEEL
GB9106185D0 (en) * 1991-03-22 1991-05-08 Wellcome Found Biological control agents
US6033903A (en) * 1995-06-02 2000-03-07 Applied Research Systems, ARS Holding N.V. Method of expressing and secreting soluble extracellular domains of human gonadotropin hormone receptors
PT1975177E (en) 1996-03-01 2011-07-26 Novo Nordisk As An appetite-suppressing peptide, its compositions and use
ES2327606T3 (en) 2000-01-10 2009-11-02 Maxygen Holdings Ltd CONJUGATES OF G-CSF.
DE60138364D1 (en) 2000-02-11 2009-05-28 Bayer Healthcare Llc CLEANING FACTOR VII OR VIIA CONJUGATE
YU48703A (en) 2001-02-27 2006-05-25 Maxygen Aps New interferon beta-like molecules
EP1373493B1 (en) 2001-03-22 2013-07-31 Novo Nordisk Health Care AG Coagulation factor vii derivative
ATE532858T1 (en) 2001-09-27 2011-11-15 Novo Nordisk Healthcare Ag HUMAN CLOTTING FACTOR VII POLYPEPTIDES
CN101870729A (en) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 Coagulation factor vii polypeptides
RU2412199C2 (en) 2005-04-18 2011-02-20 Ново Нордиск А/С Versions of il-21
EP1926817A2 (en) 2005-09-14 2008-06-04 Novo Nordisk Health Care AG Human coagulation factor vii polypeptides
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
EP2454281B1 (en) 2009-07-17 2018-11-14 Omeros Corporation Masp isoforms as inhibitors of complement activation
US9815876B2 (en) 2010-03-05 2017-11-14 Omeros Corporation Chimeric inhibitor molecules of complement activation
US20110229921A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
US9551714B2 (en) 2010-06-25 2017-01-24 Abbott Laboratories Materials and methods for assay of anti-hepatitis C virus (HCV) antibodies
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
ES2676029T3 (en) 2012-02-09 2018-07-16 Var2 Pharmaceuticals Aps Chondroitin Sulfate Glycan Addressing
WO2014060401A1 (en) 2012-10-15 2014-04-24 Novo Nordisk Health Care Ag Coagulation factor vii polypeptides
EP3821244A1 (en) 2018-07-13 2021-05-19 Varct Diagnostics ApS Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa
WO2021211331A1 (en) 2020-04-13 2021-10-21 Abbott Point Of Care Inc. METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE
US20220043000A1 (en) 2020-08-04 2022-02-10 Abbott Laboratories Methods and kits for detecting sars-cov-2 protein in a sample
WO2022147147A1 (en) 2020-12-30 2022-07-07 Abbott Laboratories Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK518384A (en) * 1984-01-31 1985-07-01 Idaho Res Found VECTOR FOR THE MANUFACTURE OF A GENE PRODUCT IN INSECT CELLS, PROCEDURE FOR ITS MANUFACTURING AND ITS USE
KR950001993B1 (en) * 1985-12-18 1995-03-08 마이크로제네시스,인코포레이티드 Production of specific polypeptide in virally infected insect cells
ZA876696B (en) * 1986-09-09 1988-05-25 Genetics Inst Method for producing a heterologous protein in insect cells

Also Published As

Publication number Publication date
CA2003248A1 (en) 1990-05-18
WO1990005783A1 (en) 1990-05-31

Similar Documents

Publication Publication Date Title
AU4647889A (en) Insect signal peptide mediated secretion of recombinant proteins
AU2928789A (en) Low ph pharmaceutical compositions of recombinant beta-interferon
AU3296589A (en) Recombinant igf binding protein (ibp-1)
AU3321595A (en) Recombinant production of biologically active peptides and proteins
AU4537393A (en) Production of recombinant polypeptides by bovine species and transgenic methods
AU8292287A (en) Purification of recombinant beta-interferon incorporating rp-hplc
AU3756789A (en) Antagonists of viral transactivating proteins
AU7474787A (en) Secretion of heterologous proteins from yeast
AU1648092A (en) Defective recombinant adenoviruses expressing characteristic epstein-barr virus proteins
KR950702242A (en) Recombinant production of saporin-containing proteins
AU7034691A (en) Lipoprotein signal peptide fused to antigenic polypeptides
FI921059A0 (en) Procedure for secretion of yeast beneficial proteins
AU7635887A (en) Recombinant HTLV-III proteins and uses thereof
AU7410987A (en) Polypeptides devoid of hydrophobic amino acids
IL103462A0 (en) Preparation of recombinant borrelia proteins
AU635023B2 (en) Retrovirus-mediated secretion of recombinant products
IL116973A0 (en) Extraction of recombinant proteins
YU219289A (en) Recombinant hybride proteins of interleucine-2
AU2117388A (en) Recombinant htlv-iii proteins and uses thereof
AU2850989A (en) Recombinant human interleukin-1 alpha polypeptides
AU4076189A (en) Recombinant fusion proteins for altering hormone secretion
FI944997A0 (en) Improved production of recombinant proteins
IL91771A0 (en) Increased expression of small molecular weight recombinant proteins
GB9104596D0 (en) Production of recombinant proteins
AU7374287A (en) Secretion of proteins from yeast