|
GB884663A
(en)
|
1958-11-06 |
1961-12-13 |
Ciba Ltd |
New amines and processes for their manufacture
|
|
CH396941A
(de)
|
1959-08-10 |
1965-08-15 |
Ciba Geigy |
Verfahren zur Herstellung neuer sekundärer Amine
|
|
GB1200886A
(en)
|
1966-09-23 |
1970-08-05 |
Allen & Hanburys Ltd |
Phenylaminoethanol derivatives
|
|
US3509153A
(en)
|
1967-03-24 |
1970-04-28 |
Miles Lab |
5-phenyl (or 5-phenylalkyl)-2-(omega-(4-phenyl-1-piperazinyl)alkyl)tetrazoles
|
|
DE2710997C3
(de)
|
1977-03-14 |
1980-08-14 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
4-Alkoxy carbonylamino-phenyläthanolamine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US4569354A
(en)
|
1982-03-22 |
1986-02-11 |
Boston University |
Method and apparatus for measuring natural retinal fluorescence
|
|
ZA848004B
(en)
*
|
1983-10-19 |
1985-06-26 |
Hoffmann La Roche |
Phenoxypropanolamines
|
|
JPH0228112A
(ja)
|
1988-04-21 |
1990-01-30 |
Kaken Pharmaceut Co Ltd |
点眼用眼圧調整剤
|
|
US5135955A
(en)
|
1988-04-25 |
1992-08-04 |
Eli Lilly And Company |
Propanamine derivatives
|
|
IT1240427B
(it)
|
1990-03-02 |
1993-12-15 |
Ministero Dall Uni E Della Ric |
Arilpropilammine ad azione antifungina
|
|
DE69224861T2
(de)
|
1991-07-30 |
1998-08-06 |
Korea Res Inst Chem Tech |
Neue Phenylacetamidderivate und Verfahren zu ihrer Herstellung
|
|
AU3481593A
(en)
|
1992-01-29 |
1993-09-01 |
Smithkline Beecham Corporation |
N-(3-phenylpropyl)oxamic acid, oxamate, and oxamide derivatives
|
|
EP0627406B1
(en)
*
|
1992-10-21 |
1998-10-28 |
Yoshitomi Pharmaceutical Industries, Ltd. |
2-amino-1,3-propanediol compound and immunosuppressant
|
|
US5958973A
(en)
*
|
1993-09-03 |
1999-09-28 |
Gilead Sciences, Inc. |
Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors
|
|
KR970700646A
(ko)
|
1994-01-19 |
1997-02-12 |
헤르베르트 루프·울리히 볼프 |
니트록시기를 포함한 벤질아민 유도체, 및 심장 혈관 질환과 안압 상승의 치료를 위한 이의 용도(nitroxy group-containing benzylamine derivatives and their use for treating cardiovascular diseases, as well as increased intra-ocular pressure)
|
|
US5541228A
(en)
|
1994-10-14 |
1996-07-30 |
Bristol-Myers Squibb Co. |
Melatonergic agents
|
|
US5693804A
(en)
*
|
1994-11-17 |
1997-12-02 |
Molecular Geriatrics Corporation |
Substituted 1-aryl-3-piperazin-1'-yl propanones
|
|
JPH0940646A
(ja)
*
|
1995-07-27 |
1997-02-10 |
Yamanouchi Pharmaceut Co Ltd |
ベンゼン縮合環誘導体又はその塩
|
|
US5641750A
(en)
|
1995-11-29 |
1997-06-24 |
Amgen Inc. |
Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product
|
|
US6090624A
(en)
|
1996-04-19 |
2000-07-18 |
Brown University Research Foundation |
Immortalized retinal cell lines and their applications
|
|
US6878544B2
(en)
|
1996-04-19 |
2005-04-12 |
Neurotech Sa |
Retinal cell lines with extended life-span and their applications
|
|
FR2747690B1
(fr)
|
1996-04-19 |
1998-06-12 |
Neurotech Sa |
Lignees immortalisees de cellules retiniennes et leurs applications au traitement de differents troubles primaires ou secondaires ophtalmologiques ou neurologiques
|
|
AUPO235996A0
(en)
|
1996-09-16 |
1996-10-10 |
Garvan Institute Of Medical Research |
Method of cell culture
|
|
CA2216439A1
(en)
|
1996-09-25 |
1998-03-25 |
Derek Van Der Kooy |
Pharmaceuticals containing retinal stem cells
|
|
DE19643592A1
(de)
|
1996-10-22 |
1998-04-23 |
Bayer Ag |
Verfahren zur Herstellung von alpha-Alkoxy-alpha-trifluormethyl-arylessigsäureestern und -arylessigsäuren
|
|
US6713300B1
(en)
|
1997-02-27 |
2004-03-30 |
University Of Utah Research Foundation |
Nucleic acid and amino acid sequences for ATP-binding cassette transporter and methods of screening for agents that modify ATP-binding cassette transporter
|
|
TW593331B
(en)
|
1997-07-25 |
2004-06-21 |
Inspire Pharmaceuticals Inc |
Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
|
|
US6051605A
(en)
|
1997-08-08 |
2000-04-18 |
Warner-Lambert Company |
Method of treating psychosis and schizophrenia
|
|
US6171837B1
(en)
|
1997-09-29 |
2001-01-09 |
The Trustees Of Columbia University In The City Of New York |
Mouse and human 9-cis-retinol dehydrogenase
|
|
AU1996599A
(en)
|
1997-12-05 |
1999-06-28 |
Board Of Trustees Of The Leland Stanford Junior University |
Long-term survival and regeneration of central nervous system neurons
|
|
US6331537B1
(en)
|
1998-06-03 |
2001-12-18 |
Gpi Nil Holdings, Inc. |
Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds
|
|
ATE402253T1
(de)
|
1999-01-05 |
2008-08-15 |
Aventis Pharma Sa |
Humane adulte astrozyten, sowie deren herstellung und verwendung
|
|
AU6391000A
(en)
|
1999-07-28 |
2001-02-19 |
Genentech Inc. |
Method of preventing the injury or death of retinal cells and treating ocular diseases
|
|
EP1107003A1
(en)
|
1999-12-09 |
2001-06-13 |
Trophos |
Methods for screening compounds active on neurons
|
|
US6406840B1
(en)
|
1999-12-17 |
2002-06-18 |
Biomosaic Systems, Inc. |
Cell arrays and the uses thereof
|
|
MXPA02006134A
(es)
|
1999-12-21 |
2002-12-13 |
Guilford Pharm Inc |
Compuestos derivados de hidantoina, composiciones farmaceuticas y metodos de uso de los mismos.
|
|
AU780364B2
(en)
|
2000-01-20 |
2005-03-17 |
Merck Sharp & Dohme Corp. |
Alpha V integrin receptor antagonists
|
|
WO2001083714A2
(en)
|
2000-05-02 |
2001-11-08 |
Central Institute For The Deaf |
Composition and methods for treating photoreceptor degeneration
|
|
US20020009713A1
(en)
|
2000-05-11 |
2002-01-24 |
Miller Freda D. |
Methods for identifying modulators of neuronal growth
|
|
BR0112484A
(pt)
*
|
2000-07-13 |
2003-09-23 |
Sankyo Co |
Composto ou um seu sal, éster ou outro derivado farmacologicamente aceitável, composição farmacêutica, uso de um composto ou de um seu sal, éster ou outro derivado farmacologicamente aceitável, e, processo para a preparação do mesmo
|
|
JP2002167382A
(ja)
*
|
2000-07-13 |
2002-06-11 |
Sankyo Co Ltd |
アミノアルコ−ル誘導体
|
|
JP2002053575A
(ja)
*
|
2000-08-09 |
2002-02-19 |
Sankyo Co Ltd |
アミノアルコ−ル類
|
|
US20030032078A1
(en)
|
2001-01-23 |
2003-02-13 |
Board Of Regents, The University Of Texas System |
Methods and compositions for the treatment of macular and retinal degenerations
|
|
DE10141018A1
(de)
|
2001-08-22 |
2003-03-13 |
Eth Zuerich Eidgenoessische Te |
Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
|
|
JP4771511B2
(ja)
*
|
2003-07-08 |
2011-09-14 |
第一三共株式会社 |
アミノアルコ−ル誘導体又はホスホン酸誘導体を含有する医薬組成物
|
|
DE60328161D1
(de)
*
|
2002-01-11 |
2009-08-13 |
Daiichi Sankyo Co Ltd |
Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
|
|
US7312025B2
(en)
|
2002-07-12 |
2007-12-25 |
University Of Washington |
Methods and systems for extended in vitro culture of neuronal cells
|
|
DE10235312A1
(de)
|
2002-08-01 |
2004-02-12 |
Basf Ag |
Verfahren zur Herstellung von Aminoalkoxybenzylaminen und Aminoalkoxybenzonitrilen als Zwischenprodukte
|
|
CN1717234A
(zh)
|
2002-12-06 |
2006-01-04 |
爱尔康公司 |
用于治疗眼紊乱和疾病的超氧化物岐化酶模拟物
|
|
KR20050105511A
(ko)
*
|
2003-03-04 |
2005-11-04 |
화이자 프로덕츠 인크. |
의학적 치료에서 ｅｐ2 선택적 수용체 효능제의 용도
|
|
EP2327401A3
(en)
|
2003-03-14 |
2011-10-19 |
University of Washington |
Retinoid Replacements and Opsin Agonists and Methods for the Use Thereof
|
|
EP1649009A2
(en)
|
2003-07-30 |
2006-04-26 |
Acucela, Inc. |
Extended primary retinal cell culture and stress models, and methods of use
|
|
ES2754221T3
(es)
|
2003-08-29 |
2020-04-16 |
Ono Pharmaceutical Co |
Compuesto capaz de unirse al receptor de S1P y uso farmacéutico del mismo
|
|
US7706863B2
(en)
|
2004-01-21 |
2010-04-27 |
University Of Washington |
Methods for assessing a physiological state of a mammalian retina
|
|
US7566808B2
(en)
|
2004-02-17 |
2009-07-28 |
President And Fellows Of Harvard College |
Management of ophthalmologic disorders, including macular degeneration
|
|
JP4242911B2
(ja)
|
2004-08-26 |
2009-03-25 |
ファイザー・インク |
プロテインキナーゼ阻害薬としてのエナンチオピュアなアミノヘテロアリール化合物
|
|
TWI359810B
(en)
*
|
2004-11-04 |
2012-03-11 |
Mitsubishi Tanabe Pharma Corp |
Carboxylic acid derivative containing thiazole rin
|
|
WO2006091796A2
(en)
|
2005-02-22 |
2006-08-31 |
Acucela, Inc. |
Compositions and methods for diagnosing and treating retinal diseases
|
|
AU2006225636A1
(en)
*
|
2005-03-22 |
2006-09-28 |
Fujifilm Corporation |
Therapeutic agent for solid tumor
|
|
US8098907B2
(en)
|
2005-07-01 |
2012-01-17 |
Siemens Corporation |
Method and system for local adaptive detection of microaneurysms in digital fundus images
|
|
TW200744567A
(en)
|
2005-09-23 |
2007-12-16 |
Alcon Inc |
Phenylethylamine analogs and their use for treating glaucoma
|
|
AU2006309173B2
(en)
*
|
2005-11-01 |
2011-08-18 |
Array Biopharma Inc. |
Glucokinase activators
|
|
CN101336229B
(zh)
*
|
2005-12-23 |
2012-06-13 |
西兰岛药物有限公司 |
改性的拟赖氨酸化合物
|
|
EP1973868B1
(en)
|
2006-01-13 |
2015-09-09 |
McGill University |
Novel elatonin ligands having antidepressant activity as well as sleep inducing properties
|
|
EP2004166A2
(en)
|
2006-03-31 |
2008-12-24 |
La Jolla Pharmaceutical Company |
Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases
|
|
JP5554988B2
(ja)
*
|
2006-04-07 |
2014-07-23 |
メチルジーン インコーポレイテッド |
ヒストンデアセチラーゼの阻害剤
|
|
KR101069089B1
(ko)
|
2006-05-23 |
2011-09-30 |
아이알엠 엘엘씨 |
채널 활성화 프로테아제 억제제로서의 화합물 및 조성물
|
|
CN101534833B
(zh)
*
|
2006-07-18 |
2013-03-13 |
贝塞斯达药理学联合有限责任公司 |
烟碱脱敏剂及选择、测试及使用它们的方法
|
|
BRPI0714683A2
(pt)
*
|
2006-07-28 |
2013-03-26 |
Pfizer Prod Inc |
agonistas ep2
|
|
MX2009011360A
(es)
|
2007-04-20 |
2010-02-12 |
Acucela Inc |
Compuestos derivados de estirenilo para tratar enfermedades y trastornos oftalmicos.
|
|
TW200906389A
(en)
*
|
2007-05-25 |
2009-02-16 |
Daiichi Sankyo Co Ltd |
Pharmaceutical composition comprising of therapeutic or prophylactic agents for hepatitis
|
|
CA2690229C
(en)
|
2007-06-29 |
2013-10-29 |
Acucela, Inc. |
Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders
|
|
US7973079B2
(en)
*
|
2007-09-27 |
2011-07-05 |
Revision Therapeutics, Inc. |
Methods and compounds for treating retinol-related diseases
|
|
WO2009045479A1
(en)
|
2007-10-05 |
2009-04-09 |
Acucela Inc. |
Alkoxy compounds for disease treatment
|
|
WO2009055696A1
(en)
*
|
2007-10-25 |
2009-04-30 |
Achaogen, Inc. |
CARBACEPHEM β-LACTAM ANTIBIOTICS
|
|
JP5592265B2
(ja)
|
2007-11-01 |
2014-09-17 |
アキュセラ インコーポレイテッド |
眼の疾患及び障害治療用のアミン誘導体化合物
|
|
WO2009113637A1
(ja)
*
|
2008-03-12 |
2009-09-17 |
東ソー株式会社 |
新規なチアゾール誘導体、チアゾール誘導体固定化マトリックス、及びそれらの製造方法
|
|
BRPI0919327A2
(pt)
|
2008-09-05 |
2019-09-24 |
Acucela Inc |
compostos ligados a enxofre para tratar doenças e distúrbios oftálmicos
|
|
NZ592993A
(en)
|
2008-10-22 |
2013-02-22 |
Acucela Inc |
Compounds for treating ophthalmic diseases and disorders
|
|
EP4000610A1
(en)
*
|
2009-07-02 |
2022-05-25 |
Acucela Inc. |
Pharmacology of visual cycle modulators
|
|
GB2474120B
(en)
|
2009-10-01 |
2011-12-21 |
Amira Pharmaceuticals Inc |
Compounds as Lysophosphatidic acid receptor antagonists
|
|
WO2013109991A1
(en)
|
2012-01-20 |
2013-07-25 |
Acucela Inc. |
Substituted heterocyclic compounds for disease treatment
|
|
TW201406707A
(zh)
|
2012-05-04 |
2014-02-16 |
Acucela Inc |
用以治療糖尿病性視網膜病變及其他眼部疾病之方法
|