RS20090002A - Ep2 agonists - Google Patents

Ep2 agonists

Info

Publication number
RS20090002A
RS20090002A RSP-2009/0002A RSP20090002A RS20090002A RS 20090002 A RS20090002 A RS 20090002A RS P20090002 A RSP20090002 A RS P20090002A RS 20090002 A RS20090002 A RS 20090002A
Authority
RS
Serbia
Prior art keywords
agonists
compounds
methods
preparation
provides
Prior art date
Application number
RSP-2009/0002A
Other languages
English (en)
Inventor
Ganesh Prasanna
Charles Floyd Bosworth
Jennifer Anne La Fontaine
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of RS20090002A publication Critical patent/RS20090002A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Ovaj pronalazak daje EP2 agoniste, postupke za njihovo dobijanje, farmaceutske preparate koji sadrže ta jedinjenja i postupke za upotrebu tih jedinjenja i preparata u snižavanju intraokularnog pritiska i na taj način tretiranja glaukoma.
RSP-2009/0002A 2006-07-28 2007-07-16 Ep2 agonists RS20090002A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83390706P 2006-07-28 2006-07-28
US94192307P 2007-06-04 2007-06-04
PCT/IB2007/002044 WO2008015517A2 (en) 2006-07-28 2007-07-16 Ep2 agonists

Publications (1)

Publication Number Publication Date
RS20090002A true RS20090002A (en) 2010-06-30

Family

ID=38896126

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2009/0002A RS20090002A (en) 2006-07-28 2007-07-16 Ep2 agonists

Country Status (26)

Country Link
US (2) US7622475B2 (sr)
EP (1) EP2059507B1 (sr)
JP (1) JP4583500B2 (sr)
KR (1) KR101088942B1 (sr)
AP (1) AP2009004754A0 (sr)
AR (1) AR062122A1 (sr)
AU (1) AU2007280130B2 (sr)
BR (1) BRPI0714683A2 (sr)
CA (1) CA2659184C (sr)
CL (1) CL2007002207A1 (sr)
CR (1) CR10554A (sr)
EA (1) EA200970067A1 (sr)
EC (1) ECSP099071A (sr)
GT (1) GT200700064A (sr)
HK (1) HK1133876A1 (sr)
IL (1) IL196355A0 (sr)
MA (1) MA30604B1 (sr)
MX (1) MX2009001062A (sr)
NO (1) NO20090738L (sr)
NZ (1) NZ573964A (sr)
PE (1) PE20080408A1 (sr)
RS (1) RS20090002A (sr)
TN (1) TN2009000028A1 (sr)
TW (1) TWI372757B (sr)
UY (1) UY30511A1 (sr)
WO (1) WO2008015517A2 (sr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009224329B2 (en) * 2008-03-12 2013-11-07 Ube Corporation Pyridylaminoacetic acid compound
CA2757291C (en) 2009-03-30 2017-05-23 Ube Industries, Ltd. Medical composition for treatment or prophylaxis of glaucoma
WO2011030865A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 置換ベンジル化合物
CA2773998A1 (en) * 2009-09-11 2011-03-17 Ube Industries, Ltd. Substituted carbonyl compound
WO2011030873A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 ベンジル化合物
WO2011030871A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 Ｎ－置換ヘテロアリール化合物
WO2011030872A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 スルホンアミド化合物
WO2011030864A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 アニリン化合物
EP2520570A4 (en) * 2009-12-25 2013-07-17 Ube Industries AMINOPYRIDINE COMPOUND
JP2013534251A (ja) * 2010-08-17 2013-09-02 アラーガン インコーポレイテッド 角膜混濁を治療するためのｅｐ２またはｅｐ４アゴニスト
KR20140097127A (ko) 2011-09-16 2014-08-06 포비어 파마수티칼스 아닐린 유도체, 그의 제조법 및 그의 치료 용도
EP2804605A4 (en) * 2012-01-20 2015-07-08 Acucela Inc SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES
EP2844638A1 (en) 2012-05-03 2015-03-11 Takeda GmbH Novel ep2 receptor agonists
US9339496B2 (en) 2012-07-13 2016-05-17 Santen Pharmaceutical Co., Ltd. Composition for treating or preventing glaucoma comprising a sulfonamide compound, and a beta-receptor antagonist
SG11201507976YA (en) 2013-03-28 2015-10-29 Ube Industries Substituted biaryl compound
JP2017206445A (ja) * 2014-09-26 2017-11-24 宇部興産株式会社 呼吸器疾患の治療及び／又は予防のための医薬組成物
JP2017206443A (ja) * 2014-09-26 2017-11-24 宇部興産株式会社 置換ビアリール化合物及び他の医薬の組み合わせ
RU2749952C2 (ru) * 2015-07-01 2021-06-21 Сантэн Фармасьютикал Ко., Лтд. Депо-препарат, содержащий сложный эфир лимонной кислоты

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599353A (en) 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
US5296504A (en) 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
UA59384C2 (uk) 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
EP1000619A3 (en) * 1998-06-23 2002-07-24 Pfizer Products Inc. Method for treating glaucoma
EP1108426A3 (en) 1999-12-02 2002-10-02 Pfizer Products Inc. Use of prostaglandin agonists to treat erectile dysfunction or impotence
US20020161026A1 (en) 2000-11-07 2002-10-31 Paralkar Vishwas M. Combination therapies for the stimulation of bone growth
KR20040063981A (ko) 2001-11-30 2004-07-15 화이자 프로덕츠 인크. Ｅｐ2 수용체 선택성 작용제를 포함하는 제약 조성물 및투여 방법
EA200400724A1 (ru) * 2002-01-31 2004-12-30 Пфайзер Продактс Инк. Метаболиты (3-{[(4-трет-бутилбензил)-(пиридин-3-сульфонил)амино]метил}фенокси)уксусной кислоты
CN1859903A (zh) 2003-03-04 2006-11-08 辉瑞产品公司 Ep2选择性受体激动剂在药物治疗中的应用
US20050203086A1 (en) 2004-03-04 2005-09-15 Pfizer Inc. Methods of treatment using an EP2 selective receptor agonist
US7915316B2 (en) * 2005-08-22 2011-03-29 Allergan, Inc Sulfonamides
US7696235B2 (en) * 2005-08-29 2010-04-13 Allergan, Inc. EP2 receptor agonists for treating glaucoma

Also Published As

Publication number Publication date
NZ573964A (en) 2010-11-26
US20100105905A1 (en) 2010-04-29
US7622475B2 (en) 2009-11-24
WO2008015517A3 (en) 2008-06-12
NO20090738L (no) 2009-04-27
JP4583500B2 (ja) 2010-11-17
WO2008015517A2 (en) 2008-02-07
CL2007002207A1 (es) 2008-02-01
EP2059507A2 (en) 2009-05-20
CA2659184C (en) 2012-02-21
JP2009544751A (ja) 2009-12-17
AP2009004754A0 (en) 2009-02-28
UY30511A1 (es) 2008-02-29
CR10554A (es) 2009-02-10
TW200817360A (en) 2008-04-16
CA2659184A1 (en) 2008-02-07
AU2007280130B2 (en) 2011-09-22
EP2059507B1 (en) 2013-03-20
PE20080408A1 (es) 2008-04-28
BRPI0714683A2 (pt) 2013-03-26
KR101088942B1 (ko) 2011-12-01
ECSP099071A (es) 2009-02-27
MX2009001062A (es) 2009-02-06
IL196355A0 (en) 2009-09-22
HK1133876A1 (en) 2010-04-09
AR062122A1 (es) 2008-10-15
KR20090023507A (ko) 2009-03-04
MA30604B1 (fr) 2009-07-01
US20080045545A1 (en) 2008-02-21
GT200700064A (es) 2009-06-18
EA200970067A1 (ru) 2009-08-28
TN2009000028A1 (fr) 2010-08-19
AU2007280130A1 (en) 2008-02-07
TWI372757B (en) 2012-09-21

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